CD28 | Beckman Coulter IM1376 product information

product summary

company name :

Beckman Coulter

other brands :

Immunotech, Diagnostic Systems Laboratories

product type :

antibody

product name :

CD28

catalog :

IM1376

quantity :

1.0 mL

price :

Request Quote

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CD28.2

reactivity :

human, Rhesus monkey

application :

flow cytometry, blocking or activating experiments

more info or order :

Beckman Coulter product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
flow cytometry; Rhesus monkey; loading ...; fig s8a	Roberts E, Carnathan D, Li H, Shaw G, Silvestri G, Betts M. Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques. PLoS Pathog. 2016;12:e1006135 pubmed publisher
flow cytometry; Rhesus monkey; loading ...; fig 2a	DeGottardi M, Okoye A, Vaidya M, Talla A, Konfe A, Reyes M, et al. Effect of Anti-IL-15 Administration on T Cell and NK Cell Homeostasis in Rhesus Macaques. J Immunol. 2016;197:1183-98 pubmed publisher
blocking or activating experiments; human; loading ...; fig 2	Maki Y, Nishimura Y, Toyooka S, Soh J, Tsukuda K, Shien K, et al. The proliferative effects of asbestos-exposed peripheral blood mononuclear cells on mesothelial cells. Oncol Lett. 2016;11:3308-3316 pubmed
flow cytometry; Rhesus monkey	Vierboom M, Breedveld E, Kap Y, Mary C, Poirier N, t Hart B, et al. Clinical efficacy of a new CD28-targeting antagonist of T cell co-stimulation in a non-human primate model of collagen-induced arthritis. Clin Exp Immunol. 2016;183:405-18 pubmed publisher
flow cytometry; Rhesus monkey; fig 4	Chowdhury A, Hayes T, Bosinger S, Lawson B, Vanderford T, Schmitz J, et al. Differential Impact of In Vivo CD8+ T Lymphocyte Depletion in Controller versus Progressor Simian Immunodeficiency Virus-Infected Macaques. J Virol. 2015;89:8677-86 pubmed publisher
flow cytometry; human; 0.2 ug/ml; fig 1	NouÃ«l A, Pochard P, Simon Q, SÃ©galen I, Le Meur Y, Pers J, et al. B-Cells induce regulatory T cells through TGF-Î²/IDO production in A CTLA-4 dependent manner. J Autoimmun. 2015;59:53-60 pubmed publisher
flow cytometry; human; tbl s5	Dimova T, Brouwer M, Gosselin F, Tassignon J, Leo O, Donner C, et al. Effector VÎ³9VÎ´2 T cells dominate the human fetal Î³Î´ T-cell repertoire. Proc Natl Acad Sci U S A. 2015;112:E556-65 pubmed publisher
flow cytometry; Rhesus monkey	Del Prete G, Shoemaker R, Oswald K, Lara A, Trubey C, Fast R, et al. Effect of suberoylanilide hydroxamic acid (SAHA) administration on the residual virus pool in a model of combination antiretroviral therapy-mediated suppression in SIVmac239-infected indian rhesus macaques. Antimicrob Agents Chemother. 2014;58:6790-806 pubmed publisher
flow cytometry; Rhesus monkey	Cartwright E, McGary C, Cervasi B, Micci L, Lawson B, Elliott S, et al. Divergent CD4+ T memory stem cell dynamics in pathogenic and nonpathogenic simian immunodeficiency virus infections. J Immunol. 2014;192:4666-73 pubmed publisher
	Henriksson J, Chen X, Gomes T, Ullah U, Meyer K, Miragaia R, et al. Genome-wide CRISPR Screens in T Helper Cells Reveal Pervasive Crosstalk between Activation and Differentiation. Cell. 2019;176:882-896.e18 pubmed publisher
	Izawa K, Martin E, Soudais C, Bruneau J, Boutboul D, Rodriguez R, et al. Inherited CD70 deficiency in humans reveals a critical role for the CD70-CD27 pathway in immunity to Epstein-Barr virus infection. J Exp Med. 2017;214:73-89 pubmed publisher
	Aijö T, Edelman S, Lönnberg T, Larjo A, Kallionpää H, Tuomela S, et al. An integrative computational systems biology approach identifies differentially regulated dynamic transcriptome signatures which drive the initiation of human T helper cell differentiation. BMC Genomics. 2012;13:572 pubmed publisher
	Di Bartolo V, Montagne B, Salek M, Jungwirth B, Carrette F, Fourtane J, et al. A novel pathway down-modulating T cell activation involves HPK-1-dependent recruitment of 14-3-3 proteins on SLP-76. J Exp Med. 2007;204:681-91 pubmed
	Dong S, Corre B, Foulon E, Dufour E, Veillette A, Acuto O, et al. T cell receptor for antigen induces linker for activation of T cell-dependent activation of a negative signaling complex involving Dok-2, SHIP-1, and Grb-2. J Exp Med. 2006;203:2509-18 pubmed
	Blanchet F, Cardona A, Letimier F, Hershfield M, Acuto O. CD28 costimulatory signal induces protein arginine methylation in T cells. J Exp Med. 2005;202:371-7 pubmed

product information

Catalog Number :

IM1376

Product Name :

CD28

Species Specificity :

Human

Host Species :

Mouse

Clonality :

Monoclonal

Conjugation :

Purified

Labeling :

ASR

Product Type :

Antibody

Size :

1.0 mL

List Price :

Request Quote

Clone :

CD28.2

Isotype :

IgG1

Product Description :

Mouse Anti-Human CD28

Immunogen :

Transfected murine cell line

Specificity :

Induces T-cell proliferation in costimulation with CD2 monoclonal antibodies. It also inhibits the CD4+ proliferation in the allogeneic T-cell response

Storage :

2-8°C

General Research References :

1. McMichael, A.J. and Gotch, F.M., 1987, in Leucocyte Typing III, White Cell Differentiation Antigens, A. J. McMichael et al., Eds., Oxford University Press, p. 30-62. 2. Olive D., Cerdan C., Costello R., Sielleur I., Ragueneau M., Pages F., Klasen S. Nunès J., Imbert J., 1995, in Leucocyte Typing V, White Cell Differentiation Antigens, S.F. Schlossman et al., Eds., Oxford University Press, p. 360-370. 3. Tan, R., Teh, S.J., Ledbetter, J.A, Linsley, P., Teh, H.S. 1992, J. Immunol., 149, 3217-3224. 4. Nunès J., Klasen S., Ragueneau M., Pavon C., Couez D., Mawas C., Bagnasco M., Olive D., 1993, International Immunology, 5, 3, 311-315.

more info or order :

Beckman Coulter product webpage