product summary
company name :
Beckman Coulter
other brands :
Immunotech, Diagnostic Systems Laboratories
product type :
antibody
product name :
CD3
catalog :
A66327
quantity :
0.5 mL
price :
Request Quote
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
UCHT1
reactivity :
human
application :
immunohistochemistry, flow cytometry
more info or order :
citations: 39
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig s4a, s8a
Schafflick D, Xu C, Hartlehnert M, Cole M, Schulte Mecklenbeck A, Lautwein T, et al. Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis. Nat Commun. 2020;11:247 pubmed publisher
  • flow cytometry; human; loading ...; fig 3b
Ingegnere T, Mariotti F, Pelosi A, Quintarelli C, De Angelis B, Tumino N, et al. Human CAR NK Cells: A New Non-viral Method Allowing High Efficient Transfection and Strong Tumor Cell Killing. Front Immunol. 2019;10:957 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a
van Erp E, Feyaerts D, Duijst M, Mulder H, Wicht O, Luytjes W, et al. Respiratory Syncytial Virus Infects Primary Neonatal and Adult Natural Killer Cells and Affects Their Antiviral Effector Function. J Infect Dis. 2019;219:723-733 pubmed publisher
  • flow cytometry; human; loading ...; fig 5a
Wang E, Pjechova M, Nightingale K, Vlahava V, Patel M, Růcková E, et al. Suppression of costimulation by human cytomegalovirus promotes evasion of cellular immune defenses. Proc Natl Acad Sci U S A. 2018;115:4998-5003 pubmed publisher
  • flow cytometry; human; loading ...; fig 3d
Molnar C, Scherer A, Baraliakos X, de Hooge M, Micheroli R, Exer P, et al. TNF blockers inhibit spinal radiographic progression in ankylosing spondylitis by reducing disease activity: results from the Swiss Clinical Quality Management cohort. Ann Rheum Dis. 2018;77:63-69 pubmed publisher
  • flow cytometry; human; loading ...; fig s1a
Suliman S, Geldenhuys H, Johnson J, Hughes J, Smit E, Murphy M, et al. Bacillus Calmette-Guérin (BCG) Revaccination of Adults with Latent Mycobacterium tuberculosis Infection Induces Long-Lived BCG-Reactive NK Cell Responses. J Immunol. 2016;197:1100-1110 pubmed publisher
  • flow cytometry; human
Eichner R, Heider M, Fernández Sáiz V, van Bebber F, Garz A, Lemeer S, et al. Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity. Nat Med. 2016;22:735-43 pubmed publisher
  • flow cytometry; human; loading ...; fig s1
Graves S, Kouriba B, Diarra I, Daou M, Niangaly A, Coulibaly D, et al. Strain-specific Plasmodium falciparum multifunctional CD4(+) T cell cytokine expression in Malian children immunized with the FMP2.1/AS02A vaccine candidate. Vaccine. 2016;34:2546-55 pubmed publisher
  • flow cytometry; human; loading ...; fig 3c
Vallera D, Felices M, McElmurry R, McCullar V, Zhou X, Schmohl J, et al. IL15 Trispecific Killer Engagers (TriKE) Make Natural Killer Cells Specific to CD33+ Targets While Also Inducing Persistence, In Vivo Expansion, and Enhanced Function. Clin Cancer Res. 2016;22:3440-50 pubmed publisher
  • flow cytometry; human; loading ...; fig 6a
Hu X, Liu C, An J, Shen Y, Hu Y, Jiang J, et al. Development of a Novel Functional Monoclonal Antibody to Human CD275: Characterization and Biological Activity. Monoclon Antib Immunodiagn Immunother. 2016;35:18-24 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 2d
Tsianakas A, Brunner P, Ghoreschi K, Berger C, Loser K, Röcken M, et al. The single-chain anti-TNF-α antibody DLX105 induces clinical and biomarker responses upon local administration in patients with chronic plaque-type psoriasis. Exp Dermatol. 2016;25:428-33 pubmed publisher
  • flow cytometry; human
Rosario M, Liu B, Kong L, Collins L, Schneider S, Chen X, et al. The IL-15-Based ALT-803 Complex Enhances FcγRIIIa-Triggered NK Cell Responses and In Vivo Clearance of B Cell Lymphomas. Clin Cancer Res. 2016;22:596-608 pubmed publisher
  • flow cytometry; human
Axelsson Robertson R, Rao M, Loxton A, Walzl G, Bates M, Zumla A, et al. Frequency of Mycobacterium tuberculosis-specific CD8+ T-cells in the course of anti-tuberculosis treatment. Int J Infect Dis. 2015;32:23-9 pubmed publisher
  • flow cytometry; human
Kamburova E, Koenen H, van den Hoogen M, Baas M, Joosten I, Hilbrands L. Longitudinal analysis of T and B cell phenotype and function in renal transplant recipients with or without rituximab induction therapy. PLoS ONE. 2014;9:e112658 pubmed publisher
  • flow cytometry; human
Perreau M, Vigano S, Bellanger F, Pellaton C, Buss G, Comte D, et al. Exhaustion of bacteria-specific CD4 T cells and microbial translocation in common variable immunodeficiency disorders. J Exp Med. 2014;211:2033-45 pubmed publisher
  • flow cytometry; human; fig 7
Schneider Hohendorf T, Rossaint J, Mohan H, Böning D, Breuer J, Kuhlmann T, et al. VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells. J Exp Med. 2014;211:1833-46 pubmed publisher
  • flow cytometry; human; loading ...; tbl 1
Okimura K, Maeta K, Kobayashi N, Goto M, Kano N, Ishihara T, et al. Characterization of ASKP1240, a fully human antibody targeting human CD40 with potent immunosuppressive effects. Am J Transplant. 2014;14:1290-9 pubmed publisher
  • flow cytometry; human; fig 1
Loh L, Ivarsson M, Michaelsson J, Sandberg J, Nixon D. Invariant natural killer T cells developing in the human fetus accumulate and mature in the small intestine. Mucosal Immunol. 2014;7:1233-43 pubmed publisher
  • flow cytometry; human
Lanteri M, Diamond M, Law J, Chew G, Wu S, Inglis H, et al. Increased frequency of Tim-3 expressing T cells is associated with symptomatic West Nile virus infection. PLoS ONE. 2014;9:e92134 pubmed publisher
  • flow cytometry; human; fig 1
Salerno Goncalves R, Rezwan T, Sztein M. B cells modulate mucosal associated invariant T cell immune responses. Front Immunol. 2014;4:511 pubmed publisher
  • flow cytometry; human
Wiernik A, Foley B, Zhang B, Verneris M, Warlick E, Gleason M, et al. Targeting natural killer cells to acute myeloid leukemia in vitro with a CD16 x 33 bispecific killer cell engager and ADAM17 inhibition. Clin Cancer Res. 2013;19:3844-55 pubmed publisher
  • flow cytometry; human
Takahashi A, Torigoe T, Tamura Y, Kanaseki T, Tsukahara T, Sasaki Y, et al. Heat shock enhances the expression of cytotoxic granule proteins and augments the activities of tumor-associated antigen-specific cytotoxic T lymphocytes. Cell Stress Chaperones. 2012;17:757-63 pubmed publisher
Matsueda K, Iwamuro M, Takahashi T, Omote S, Nishida K, Tanaka T, et al. Feasibility of flow cytometric analysis of restricted light chain in endoscopic biopsy specimens from patients with gastrointestinal tract B cell lymphoma: a pilot study. BMC Res Notes. 2019;12:571 pubmed publisher
Bencsikova B, Budinska E, Selingerova I, Pilatova K, Fedorová L, Greplova K, et al. Circulating T cell subsets are associated with clinical outcome of anti-VEGF-based 1st-line treatment of metastatic colorectal cancer patients: a prospective study with focus on primary tumor sidedness. BMC Cancer. 2019;19:687 pubmed publisher
Tesini B, Kanagaiah P, Wang J, Hahn M, Halliley J, Chaves F, et al. Broad Hemagglutinin-Specific Memory B Cell Expansion by Seasonal Influenza Virus Infection Reflects Early-Life Imprinting and Adaptation to the Infecting Virus. J Virol. 2019;93: pubmed publisher
Graustein A, Misch E, Musvosvi M, Shey M, Shah J, Seshadri C, et al. Toll-like receptor chaperone HSP90B1 and the immune response to Mycobacteria. PLoS ONE. 2018;13:e0208940 pubmed publisher
Andre P, Denis C, Soulas C, Bourbon Caillet C, Lopez J, Arnoux T, et al. Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells. Cell. 2018;175:1731-1743.e13 pubmed publisher
Schmidt A, Marabita F, Kiani N, Gross C, Johansson H, Elias S, et al. Time-resolved transcriptome and proteome landscape of human regulatory T cell (Treg) differentiation reveals novel regulators of FOXP3. BMC Biol. 2018;16:47 pubmed publisher
Duployez N, Boudry Labis E, Roumier C, Boissel N, Petit A, Geffroy S, et al. SNP-array lesions in core binding factor acute myeloid leukemia. Oncotarget. 2018;9:6478-6489 pubmed publisher
Chan Y, Zuo J, Inman C, Croft W, Begum J, Croudace J, et al. NK cells produce high levels of IL-10 early after allogeneic stem cell transplantation and suppress development of acute GVHD. Eur J Immunol. 2018;48:316-329 pubmed publisher
Gaidt M, Ebert T, Chauhan D, Ramshorn K, Pinci F, Zuber S, et al. The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3. Cell. 2017;171:1110-1124.e18 pubmed publisher
Hensel M, Peng T, Cheng A, De Rosa S, Wald A, Laing K, et al. Selective Expression of CCR10 and CXCR3 by Circulating Human Herpes Simplex Virus-Specific CD8 T Cells. J Virol. 2017;91: pubmed publisher
Schofield L, Ioannidis L, Karl S, Robinson L, Tan Q, Poole D, et al. Synergistic effect of IL-12 and IL-18 induces TIM3 regulation of ?? T cell function and decreases the risk of clinical malaria in children living in Papua New Guinea. BMC Med. 2017;15:114 pubmed publisher
Cottineau J, Kottemann M, Lach F, Kang Y, Vély F, Deenick E, et al. Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency. J Clin Invest. 2017;127:1991-2006 pubmed publisher
Izawa K, Martin E, Soudais C, Bruneau J, Boutboul D, Rodriguez R, et al. Inherited CD70 deficiency in humans reveals a critical role for the CD70-CD27 pathway in immunity to Epstein-Barr virus infection. J Exp Med. 2017;214:73-89 pubmed publisher
Sekine T, Marin D, Cao K, Li L, Mehta P, Shaim H, et al. Specific combinations of donor and recipient KIR-HLA genotypes predict for large differences in outcome after cord blood transplantation. Blood. 2016;128:297-312 pubmed publisher
Foley B, Cooley S, Verneris M, Curtsinger J, Luo X, Waller E, et al. Human cytomegalovirus (CMV)-induced memory-like NKG2C(+) NK cells are transplantable and expand in vivo in response to recipient CMV antigen. J Immunol. 2012;189:5082-8 pubmed publisher
Stary G, Bangert C, Tauber M, Strohal R, Kopp T, Stingl G. Tumoricidal activity of TLR7/8-activated inflammatory dendritic cells. J Exp Med. 2007;204:1441-51 pubmed
Frumento G, Rotondo R, Tonetti M, Damonte G, Benatti U, Ferrara G. Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase. J Exp Med. 2002;196:459-68 pubmed
product information
Catalog Number :
A66327
Product Name :
CD3
Species Specificity :
Human
Host Species :
Mouse
Clonality :
Monoclonal
Conjugation :
PC5.5
Labeling :
ASR
Product Type :
Antibody
Size :
0.5 mL
List Price :
Request Quote
Clone :
UCHT1
Isotype :
IgG1
Product Description :
Mouse Anti-Human CD3
Immunogen :
Peripheral blood lymphocytes
Specificity :
Reacts with the epsilon chain of the CD3 complex
Storage :
2-8°C
General Research References :
1. Hannet, I., Erkeller-Yuksel, F., Lydyard, P., Deneys, V., DeBruyère, M., 1992, Immunol. Today, 6, 13, 215-218. 2. Thibault, G., Bardos, P., 1995, J. Immunol., 154, 3814-3820. 3. Sprent, J., 1989, Fundamental Immunology, Chap 4, 2nd Ed., 69-93. 4. Shores, E.W., Love, P.E., 1997, Cur. Opin. Immunol., 9, 380-389. 5. Ono, S., Ohno, H., Saito, T., 1995, Immunity, 2, 639-644. 6. Julius, M., Maroun, C.R., Haughn, L., 1993, Immunol. Today, 4, 14, 177-183. 7. van Agthoven, A., Terhorst, C., Reinherz, E.L., Schlossman, S.F., 1981, Eur. J. Immunol., 11, 18-21 8. Tunnacliffe, A., Olsson, C., Traunecker, A., et al., 1989, Leucocyte Typing IV, White Cell Differentiation Antigens. W. Knapp, et al., Eds., Oxford University Press, 295-296. 9. Van Lochem, E.G., Groeneveld, K., Te Marvelde, J.G., Hooijkaas, H., Van Dongen, J.J.M., 1997, Leukemia, in press, 11. 10. Urbano-Ispizua, A., Matutes, E., Villamor, N., et al., 1992, Br. J. Haematol., 81, 178-183. 11. Bernard, A., Brottier, P., Georget, E., Lepage, V., Boumsell, L., 1984, Leucocyte Typing I, Bernard, A. et al., Springer Verlag, 9-135.
more info or order :
company information
Beckman Coulter
11800 S.W. 147th Avenue
Miami FL 33196
http://www.beckmancoulter.com
305 380-3800
headquarters: United States