CD28 | Beckman Coulter 6607108 product information

product summary

company name :

Beckman Coulter

other brands :

Immunotech, Diagnostic Systems Laboratories

product type :

antibody

product name :

CD28

catalog :

6607108

quantity :

100 tests

price :

Request Quote

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CD28.2

reactivity :

human, rhesus macaque

application :

flow cytometry

more info or order :

Beckman Coulter product webpage

citations: 16

Published Application/Species/Sample/Dilution	Reference
flow cytometry; rhesus macaque; loading ...; fig s8a	Roberts E, Carnathan D, Li H, Shaw G, Silvestri G, Betts M. Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques. PLoS Pathog. 2016;12:e1006135 pubmed publisher
flow cytometry; rhesus macaque; loading ...; fig 2a	DeGottardi M, Okoye A, Vaidya M, Talla A, Konfe A, Reyes M, et al. Effect of Anti-IL-15 Administration on T Cell and NK Cell Homeostasis in Rhesus Macaques. J Immunol. 2016;197:1183-98 pubmed publisher
flow cytometry; rhesus macaque	Vierboom M, Breedveld E, Kap Y, Mary C, Poirier N, t Hart B, et al. Clinical efficacy of a new CD28-targeting antagonist of T cell co-stimulation in a non-human primate model of collagen-induced arthritis. Clin Exp Immunol. 2016;183:405-18 pubmed publisher
flow cytometry; rhesus macaque; fig 4	Chowdhury A, Hayes T, Bosinger S, Lawson B, Vanderford T, Schmitz J, et al. Differential Impact of In Vivo CD8+ T Lymphocyte Depletion in Controller versus Progressor Simian Immunodeficiency Virus-Infected Macaques. J Virol. 2015;89:8677-86 pubmed publisher
flow cytometry; human; 0.2 ug/ml; fig 1	NouÃ«l A, Pochard P, Simon Q, SÃ©galen I, Le Meur Y, Pers J, et al. B-Cells induce regulatory T cells through TGF-Î²/IDO production in A CTLA-4 dependent manner. J Autoimmun. 2015;59:53-60 pubmed publisher
flow cytometry; human; tbl s5	Dimova T, Brouwer M, Gosselin F, Tassignon J, Leo O, Donner C, et al. Effector VÎ³9VÎ´2 T cells dominate the human fetal Î³Î´ T-cell repertoire. Proc Natl Acad Sci U S A. 2015;112:E556-65 pubmed publisher
flow cytometry; rhesus macaque	Del Prete G, Shoemaker R, Oswald K, Lara A, Trubey C, Fast R, et al. Effect of suberoylanilide hydroxamic acid (SAHA) administration on the residual virus pool in a model of combination antiretroviral therapy-mediated suppression in SIVmac239-infected indian rhesus macaques. Antimicrob Agents Chemother. 2014;58:6790-806 pubmed publisher
flow cytometry; rhesus macaque	Cartwright E, McGary C, Cervasi B, Micci L, Lawson B, Elliott S, et al. Divergent CD4+ T memory stem cell dynamics in pathogenic and nonpathogenic simian immunodeficiency virus infections. J Immunol. 2014;192:4666-73 pubmed publisher
	Mavigner M, Habib J, Deléage C, Rosen E, Mattingly C, Bricker K, et al. Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques. J Virol. 2018;92: pubmed publisher
	Xiao P, Gumber S, Marzinke M, Date A, Hoang T, Hanes J, et al. Hypo-osmolar Formulation of Tenofovir (TFV) Enema Promotes Uptake and Metabolism of TFV in Tissues, Leading to Prevention of SHIV/SIV Infection. Antimicrob Agents Chemother. 2018;62: pubmed publisher
	Zhang Y, Kurupati R, Liu L, Zhou X, Zhang G, Hudaihed A, et al. Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy. Cancer Cell. 2017;32:377-391.e9 pubmed publisher
	Fujino M, Sato H, Okamura T, Uda A, Takeda S, Ahmed N, et al. Simian Immunodeficiency Virus Targeting of CXCR3+ CD4+ T Cells in Secondary Lymphoid Organs Is Associated with Robust CXCL10 Expression in Monocyte/Macrophage Subsets. J Virol. 2017;91: pubmed publisher
	Izawa K, Martin E, Soudais C, Bruneau J, Boutboul D, Rodriguez R, et al. Inherited CD70 deficiency in humans reveals a critical role for the CD70-CD27 pathway in immunity to Epstein-Barr virus infection. J Exp Med. 2017;214:73-89 pubmed publisher
	Di Bartolo V, Montagne B, Salek M, Jungwirth B, Carrette F, Fourtane J, et al. A novel pathway down-modulating T cell activation involves HPK-1-dependent recruitment of 14-3-3 proteins on SLP-76. J Exp Med. 2007;204:681-91 pubmed
	Dong S, Corre B, Foulon E, Dufour E, Veillette A, Acuto O, et al. T cell receptor for antigen induces linker for activation of T cell-dependent activation of a negative signaling complex involving Dok-2, SHIP-1, and Grb-2. J Exp Med. 2006;203:2509-18 pubmed
	Blanchet F, Cardona A, Letimier F, Hershfield M, Acuto O. CD28 costimulatory signal induces protein arginine methylation in T cells. J Exp Med. 2005;202:371-7 pubmed

product information

Catalog Number :

6607108

Product Name :

CD28

Species Specificity :

Human

Host Species :

Mouse

Clonality :

Monoclonal

Conjugation :

PC5

Labeling :

RUO

Product Type :

Antibody

Size :

100 tests

List Price :

Request Quote

Clone :

CD28.2

Isotype :

IgG1

Product Description :

Mouse Anti-Human CD28

Immunogen :

Transfected murine cell line

Specificity :

Induces T-cell proliferation in costimulation with CD2 monoclonal antibodies. It also inhibits the CD4+ proliferation in the allogeneic T-cell response

Applications :

Flow Cytometry

Storage :

2-8°C

General Research References :

1. McMichael, A.J. and Gotch, F.M., 1987, in Leucocyte Typing III, White Cell Differentiation Antigens, A. J. McMichael et al., Eds., Oxford University Press, p. 30-62. 2. Olive D., Cerdan C., Costello R., Sielleur I., Ragueneau M., Pages F., Klasen S. Nunès J., Imbert J., 1995, in Leucocyte Typing V, White Cell Differentiation Antigens, S.F. Schlossman et al., Eds., Oxford University Press, p. 360-370. 3. Tan, R., Teh, S.J., Ledbetter, J.A, Linsley, P., Teh, H.S. 1992, J. Immunol., 149, 3217-3224. 4. Nunès J., Klasen S., Ragueneau M., Pavon C., Couez D., Mawas C., Bagnasco M., Olive D., 1993, International Immunology, 5, 3, 311-315.

more info or order :

Beckman Coulter product webpage