HIV-1 core antigen | Beckman Coulter 6604667 product information

product summary

company name :

Beckman Coulter

other brands :

Immunotech, Diagnostic Systems Laboratories

product type :

antibody

product name :

HIV-1 core antigen

catalog :

6604667

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

KC57

reactivity :

human, mouse, Human immunodeficiency virus 1

application :

immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

Beckman Coulter product webpage

citations: 23

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:1000; loading ...; fig s8b	Wang Q, Gao H, Clark K, Mugisha C, Davis K, Tang J, et al. CARD8 is an inflammasome sensor for HIV-1 protease activity. Science. 2021;371: pubmed publisher
flow cytometry; Human immunodeficiency virus 1; loading ...; fig 1b	Lubow J, Virgilio M, Merlino M, Collins D, Mashiba M, Peterson B, et al. Mannose receptor is an HIV restriction factor counteracted by Vpr in macrophages. elife. 2020;9: pubmed publisher
flow cytometry; human; loading ...; fig s2	Clayton K, Collins D, Lengieza J, Ghebremichael M, Dotiwala F, Lieberman J, et al. Resistance of HIV-infected macrophages to CD8+ T lymphocyte-mediated killing drives activation of the immune system. Nat Immunol. 2018;19:475-486 pubmed publisher
flow cytometry; Human immunodeficiency virus 1; loading ...; fig 1b	Cenker J, Stultz R, McDonald D. Brain Microglial Cells Are Highly Susceptible to HIV-1 Infection and Spread. AIDS Res Hum Retroviruses. 2017;33:1155-1165 pubmed publisher
flow cytometry; Human immunodeficiency virus 1; loading ...	Zhen A, Rezek V, Youn C, Lam B, Chang N, Rick J, et al. Targeting type I interferon-mediated activation restores immune function in chronic HIV infection. J Clin Invest. 2017;127:260-268 pubmed publisher
flow cytometry; Human immunodeficiency virus 1; fig s4f	Ribeiro C, Sarrami Forooshani R, Setiawan L, Zijlstra Willems E, van Hamme J, Tigchelaar W, et al. Receptor usage dictates HIV-1 restriction by human TRIM5? in dendritic cell subsets. Nature. 2016;540:448-452 pubmed publisher
flow cytometry; human; 1:100; fig 3	Park A, Hong P, Won S, Thibault P, Vigant F, Oguntuyo K, et al. Sendai virus, an RNA virus with no risk of genomic integration, delivers CRISPR/Cas9 for efficient gene editing. Mol Ther Methods Clin Dev. 2016;3:16057 pubmed publisher
flow cytometry; Human immunodeficiency virus 1; loading ...; fig 1b immunocytochemistry; Human immunodeficiency virus 1; loading ...; fig 5f	Coulon P, Richetta C, Rouers A, Blanchet F, Urrutia A, Guerbois M, et al. HIV-Infected Dendritic Cells Present Endogenous MHC Class II-Restricted Antigens to HIV-Specific CD4+ T Cells. J Immunol. 2016;197:517-32 pubmed publisher
flow cytometry; Human immunodeficiency virus 1; fig 1	Tang J, DROKHLYANSKY E, Etemad B, Rudolph S, Guo B, Wang S, et al. Detection and manipulation of live antigen-expressing cells using conditionally stable nanobodies. elife. 2016;5: pubmed publisher
flow cytometry; Human immunodeficiency virus 1; fig 5	Luo X, Fan Y, Park I, He J. Exosomes are unlikely involved in intercellular Nef transfer. PLoS ONE. 2015;10:e0124436 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:250	Vassena L, Giuliani E, Koppensteiner H, Bolduan S, Schindler M, Doria M. HIV-1 Nef and Vpu Interfere with L-Selectin (CD62L) Cell Surface Expression To Inhibit Adhesion and Signaling in Infected CD4+ T Lymphocytes. J Virol. 2015;89:5687-700 pubmed publisher
flow cytometry; Human immunodeficiency virus 1; fig 1	LambelÃ© M, Koppensteiner H, Symeonides M, Roy N, Chan J, Schindler M, et al. Vpu is the main determinant for tetraspanin downregulation in HIV-1-infected cells. J Virol. 2015;89:3247-55 pubmed publisher
	Murakami T, Kim J, Li Y, Green G, Shikanov A, Ono A. Secondary lymphoid organ fibroblastic reticular cells mediate trans-infection of HIV-1 via CD44-hyaluronan interactions. Nat Commun. 2018;9:2436 pubmed publisher
	Buttler C, Pezeshkian N, Fernandez M, Aaron J, Norman S, Freed E, et al. Single molecule fate of HIV-1 envelope reveals late-stage viral lattice incorporation. Nat Commun. 2018;9:1861 pubmed publisher
	Roesch F, OhAinle M, Emerman M. A CRISPR screen for factors regulating SAMHD1 degradation identifies IFITMs as potent inhibitors of lentiviral particle delivery. Retrovirology. 2018;15:26 pubmed publisher
	Huang S, Ren Y, Thomas A, Chan D, Mueller S, Ward A, et al. Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells. J Clin Invest. 2018;128:876-889 pubmed publisher
	Mujib S, Liu J, Rahman A, Schwartz J, Bonner P, Yue F, et al. Comprehensive Cross-Clade Characterization of Antibody-Mediated Recognition, Complement-Mediated Lysis, and Cell-Mediated Cytotoxicity of HIV-1 Envelope-Specific Antibodies toward Eradication of the HIV-1 Reservoir. J Virol. 2017;91: pubmed publisher
	Park R, Wang T, Koundakjian D, Hultquist J, Lamothe Molina P, Monel B, et al. A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors. Nat Genet. 2017;49:193-203 pubmed publisher
	da Silva Santos C, Tartour K, Cimarelli A. A Novel Entry/Uncoating Assay Reveals the Presence of at Least Two Species of Viral Capsids During Synchronized HIV-1 Infection. PLoS Pathog. 2016;12:e1005897 pubmed publisher
	Alter G, Martin M, Teigen N, Carr W, Suscovich T, Schneidewind A, et al. Differential natural killer cell-mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes. J Exp Med. 2007;204:3027-36 pubmed
	Kreisberg J, Yonemoto W, Greene W. Endogenous factors enhance HIV infection of tissue naive CD4 T cells by stimulating high molecular mass APOBEC3G complex formation. J Exp Med. 2006;203:865-70 pubmed
	Lore K, Smed Sorensen A, Vasudevan J, Mascola J, Koup R. Myeloid and plasmacytoid dendritic cells transfer HIV-1 preferentially to antigen-specific CD4+ T cells. J Exp Med. 2005;201:2023-33 pubmed
	Janardhan A, Swigut T, Hill B, Myers M, Skowronski J. HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis. PLoS Biol. 2004;2:E6 pubmed

product information

Catalog Number :

6604667

Product Name :

HIV-1 core antigen

Species Specificity :

Human

Host Species :

Mouse

Clonality :

Monoclonal

Conjugation :

RD1

Labeling :

RUO

Product Type :

Antibody

Size :

100 tests

Clone :

KC57

Isotype :

IgG1

Product Description :

Mouse Anti-Human HIV-1 core antigen

Immunogen :

Purified HIV-18E5/LAV

Specificity :

The KC57 antibody identifies on Western blot the 55, 39, 33 and 24 kD proteins of the core antigens of the Human Immunodeficiency Virus Type 1 (HIV-1).

Applications :

Flow Cytometry

Storage :

2-8°C

General Research References :

1. Robey WG, Safai B, Oroszlan S, Arthur LO, Gonda MA, Gallo RC and Fischinger PJ. 1985. Science 228:593-595. 2. Chassagne J, Verrele P, Dionet C, Clavel F, Barre- Sinoussi F, Chermann JC, Montagnier L, Gluckman JC and Klatzmann D. 1986. J Immunol 136:1442-1445. 3. Schupbach J, Popovic M, Gilden RV, Gonda MA, Sargadharan MG and Gallo RC. 1984. Science 224:503-505.

more info or order :

Beckman Coulter product webpage