product summary
company name :
Beckman Coulter
other brands :
Immunotech, Diagnostic Systems Laboratories
product type :
antibody
product name :
HIV-1 core antigen
catalog :
6604665
quantity :
100 tests
price :
Request Quote
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
KC57
reactivity :
human, mouse, Human immunodeficiency virus 1
application :
immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 12
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 1:25; loading ...; fig 1s2a
Langer S, Hammer C, Hopfensperger K, Klein L, Hotter D, De Jesus P, et al. HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses. elife. 2019;8: pubmed publisher
  • flow cytometry; human; loading ...; fig 5b, 6a
Mwimanzi F, Toyoda M, Mahiti M, Mann J, Martin J, Bangsberg D, et al. Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals. J Virol. 2018;92: pubmed publisher
  • flow cytometry; Human immunodeficiency virus 1; loading ...; fig 1b
Cenker J, Stultz R, McDonald D. Brain Microglial Cells Are Highly Susceptible to HIV-1 Infection and Spread. AIDS Res Hum Retroviruses. 2017;33:1155-1165 pubmed publisher
  • flow cytometry; human; loading ...
  • immunocytochemistry; human; loading ...; fig 6a, S5
Hammonds J, Beeman N, Ding L, Takushi S, Francis A, Wang J, et al. Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1. PLoS Pathog. 2017;13:e1006181 pubmed publisher
  • flow cytometry; Human immunodeficiency virus 1; loading ...; fig 1b
  • immunocytochemistry; Human immunodeficiency virus 1; loading ...; fig 5f
Coulon P, Richetta C, Rouers A, Blanchet F, Urrutia A, Guerbois M, et al. HIV-Infected Dendritic Cells Present Endogenous MHC Class II-Restricted Antigens to HIV-Specific CD4+ T Cells. J Immunol. 2016;197:517-32 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:250
Vassena L, Giuliani E, Koppensteiner H, Bolduan S, Schindler M, Doria M. HIV-1 Nef and Vpu Interfere with L-Selectin (CD62L) Cell Surface Expression To Inhibit Adhesion and Signaling in Infected CD4+ T Lymphocytes. J Virol. 2015;89:5687-700 pubmed publisher
  • flow cytometry; Human immunodeficiency virus 1; fig 1
Lambelé M, Koppensteiner H, Symeonides M, Roy N, Chan J, Schindler M, et al. Vpu is the main determinant for tetraspanin downregulation in HIV-1-infected cells. J Virol. 2015;89:3247-55 pubmed publisher
  • flow cytometry; Human immunodeficiency virus 1; fig 4
Li G, Cheng M, Nunoya J, Cheng L, Guo H, Yu H, et al. Plasmacytoid dendritic cells suppress HIV-1 replication but contribute to HIV-1 induced immunopathogenesis in humanized mice. PLoS Pathog. 2014;10:e1004291 pubmed publisher
Heusinger E, Deppe K, Sette P, Krapp C, Kmiec D, Kluge S, et al. Preadaptation of Simian Immunodeficiency Virus SIVsmm Facilitated Env-Mediated Counteraction of Human Tetherin by Human Immunodeficiency Virus Type 2. J Virol. 2018;92: pubmed publisher
Murakami T, Kim J, Li Y, Green G, Shikanov A, Ono A. Secondary lymphoid organ fibroblastic reticular cells mediate trans-infection of HIV-1 via CD44-hyaluronan interactions. Nat Commun. 2018;9:2436 pubmed publisher
Prasad A, Kulkarni R, Jiang S, Groopman J. Cocaine Enhances DC to T-cell HIV-1 Transmission by Activating DC-SIGN/LARG/LSP1 Complex and Facilitating Infectious Synapse Formation. Sci Rep. 2017;7:40648 pubmed publisher
Shrivastava A, Prasad A, Kuzontkoski P, Yu J, Groopman J. Slit2N Inhibits Transmission of HIV-1 from Dendritic Cells to T-cells by Modulating Novel Cytoskeletal Elements. Sci Rep. 2015;5:16833 pubmed publisher
product information
Catalog Number :
6604665
Product Name :
HIV-1 core antigen
Species Specificity :
Human
Host Species :
Mouse
Clonality :
Monoclonal
Conjugation :
FITC
Labeling :
RUO
Product Type :
Antibody
Size :
100 tests
List Price :
Request Quote
Clone :
KC57
Isotype :
IgG1
Product Description :
Mouse Anti-Human HIV-1 core antigen
Immunogen :
Purified HIV-18E5/LAV
Specificity :
The KC57 antibody identifies on Western blot the 55, 39, 33 and 24 kD proteins of the core antigens of the Human Immunodeficiency Virus Type 1 (HIV-1).
Applications :
Flow Cytometry
Storage :
2-8°C
General Research References :
1. Robey WG, Safai B, Oroszlan S, Arthur LO, Gonda MA, Gallo RC and Fischinger PJ. 1985. Science 228:593-595. 2. Chassagne J, Verrele P, Dionet C, Clavel F, Barre- Sinoussi F, Chermann JC, Montagnier L, Gluckman JC and Klatzmann D. 1986. J Immunol 136:1442-1445. 3. Schupbach J, Popovic M, Gilden RV, Gonda MA, Sargadharan MG and Gallo RC. 1984. Science 224:503-505.
more info or order :
company information
Beckman Coulter
11800 S.W. 147th Avenue
Miami FL 33196
http://www.beckmancoulter.com
305 380-3800
headquarters: United States