product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
ER Alpha / Estrogen Receptor Antibody (N-Terminus) LS-C83436
catalog :
LS-C83436
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunoprecipitation
more info or order :
LifeSpan Biosciences product webpage
product information
?AntibodyID :
84275
AntibodyName :
LS-C83436
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
ER Alpha / Estrogen Receptor Antibody (N-Terminus) LS-C83436
Specificity :
Recognizes human ER-a, a 65 kD protein and a member of the steroid family of nuclear receptors. ER-a is a ligand-activated transcription factor that, when bound to estrogen, induces a conformational change that allows dimerization and binding to estrogen response element sequences. When bound to DNA, ER-a can positively or negatively regulate gene transcription.
ClonalityDesc :
Monoclonal
AntibodyModification :
Unconjugated
AntigenModification :
N-Terminus
PresentationDesc :
PBS, pH 7.4
ImmunogenType :
Fusion protein
ImmunogenDesc :
6-His fusion protein containing the region encoding aa 1-190 of human estrogen receptor-a (ER-a) expressed in E. coli.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at -70°C, avoid freeze/thaw cycles.
IsotypeName :
IgG1
Gene :
ER Alpha / Estrogen Receptor
StandardGeneSymbol :
ESR1
gene family :
NHR
Subfamily :
NR3 Steroid receptor
Reactivity :
Human
Usage :
IP (1 - 5 µg/ml), WB
Synonyms :
ESR1, Era, ERalpha, Estrogen receptor, Estradiol receptor, ER-alpha, Estrogen receptor 1, NR3A1, ER, ESR, ESRA, Estrogen receptor alpha
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.