| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunocytochemistry knockout validation; mouse; loading ...; fig 1b
- immunocytochemistry; human; loading ...; fig 1a
- western blot; human; loading ...; fig 1c
| Wang X, Cao W, Zhang J, Yan M, Xu Q, Wu X, et al. A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination. EMBO J. 2017;36:1243-1260 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 1c
| Brady N, Bagadion A, Singh R, Conteduca V, Van Emmenis L, Arceci E, et al. Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer. Nat Commun. 2021;12:3372 pubmed publisher |
- western blot; human; loading ...; fig 4a
| Ma W, Tummers B, van Esch E, Goedemans R, Melief C, Meyers C, et al. Human Papillomavirus Downregulates the Expression of IFITM1 and RIPK3 to Escape from IFN?- and TNF?-Mediated Antiproliferative Effects and Necroptosis. Front Immunol. 2016;7:496 pubmed |
- immunohistochemistry - frozen section; human; 1:100
- flow cytometry; human; fig 1
- western blot; human; 1:1000
| Zhao E, Maj T, Kryczek I, Li W, Wu K, Zhao L, et al. Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction. Nat Immunol. 2016;17:95-103 pubmed publisher |
- western blot; human; 1:2000; fig s2
| Peng D, Kryczek I, Nagarsheth N, Zhao L, Wei S, Wang W, et al. Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy. Nature. 2015;527:249-53 pubmed publisher |
- western blot; human; 1:1000
| Adhikary G, Grun D, Balasubramanian S, Kerr C, Huang J, Eckert R. Survival of skin cancer stem cells requires the Ezh2 polycomb group protein. Carcinogenesis. 2015;36:800-10 pubmed publisher |
- western blot; zebrafish ; 1:1000
| Tien C, Jones A, Wang H, Gerigk M, Nozell S, Chang C. Snail2/Slug cooperates with Polycomb repressive complex 2 (PRC2) to regulate neural crest development. Development. 2015;142:722-31 pubmed publisher |
- chromatin immunoprecipitation; mouse; fig 1
- western blot; mouse; fig 3
| Shi X, Zhang Z, Zhan X, Cao M, Satoh T, Akira S, et al. An epigenetic switch induced by Shh signalling regulates gene activation during development and medulloblastoma growth. Nat Commun. 2014;5:5425 pubmed publisher |
- immunohistochemistry - paraffin section; human
| Benard A, Goossens Beumer I, van Hoesel A, Horati H, Putter H, Zeestraten E, et al. Prognostic value of polycomb proteins EZH2, BMI1 and SUZ12 and histone modification H3K27me3 in colorectal cancer. PLoS ONE. 2014;9:e108265 pubmed publisher |
| Tong Q, He S, Xie F, Mochizuki K, Liu Y, Mochizuki I, et al. Ezh2 regulates transcriptional and posttranslational expression of T-bet and promotes Th1 cell responses mediating aplastic anemia in mice. J Immunol. 2014;192:5012-22 pubmed publisher |
- immunoprecipitation; human; 1:1000
- western blot; human; 1:1000
| Cao Q, Wang X, Zhao M, Yang R, Malik R, Qiao Y, et al. The central role of EED in the orchestration of polycomb group complexes. Nat Commun. 2014;5:3127 pubmed publisher |
- western blot; human; 1:1000
| Adhikary G, Grun D, Kerr C, Balasubramanian S, Rorke E, Vemuri M, et al. Identification of a population of epidermal squamous cell carcinoma cells with enhanced potential for tumor formation. PLoS ONE. 2013;8:e84324 pubmed publisher |
| Wu L, Runkle C, Jin H, Li J, Yang X, Kuzel T, et al. CCN3/NOV gene expression in human prostate cancer is directly suppressed by the androgen receptor. Oncogene. 2014;33:504-13 pubmed publisher |
| Burr M, Sparbier C, Chan K, Chan Y, Kersbergen A, Lam E, et al. An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer. Cancer Cell. 2019;36:385-401.e8 pubmed publisher |
| Li F, Zeng Z, Xing S, Gullicksrud J, Shan Q, Choi J, et al. Ezh2 programs TFH differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf. Nat Commun. 2018;9:5452 pubmed publisher |
| Yamaguchi H, Du Y, Nakai K, Ding M, Chang S, Hsu J, et al. EZH2 contributes to the response to PARP inhibitors through its PARP-mediated poly-ADP ribosylation in breast cancer. Oncogene. 2018;37:208-217 pubmed publisher |
| Kurihara H, Maruyama R, Ishiguro K, Kanno S, Yamamoto I, Ishigami K, et al. The relationship between EZH2 expression and microRNA-31 in colorectal cancer and the role in evolution of the serrated pathway. Oncotarget. 2016;7:12704-17 pubmed publisher |
| Beltran H, Prandi D, Mosquera J, Benelli M, Puca L, Cyrta J, et al. Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer. Nat Med. 2016;22:298-305 pubmed publisher |
| Boo K, Bhin J, Jeon Y, Kim J, Shin H, Park J, et al. Pontin functions as an essential coactivator for Oct4-dependent lincRNA expression in mouse embryonic stem cells. Nat Commun. 2015;6:6810 pubmed publisher |
| Ferraro A, Boni T, Pintzas A. EZH2 regulates cofilin activity and colon cancer cell migration by targeting ITGA2 gene. PLoS ONE. 2014;9:e115276 pubmed publisher |
| Fussbroich B, Wagener N, Macher Goeppinger S, Benner A, Fälth M, Sultmann H, et al. EZH2 depletion blocks the proliferation of colon cancer cells. PLoS ONE. 2011;6:e21651 pubmed publisher |
| Kunderfranco P, Mello Grand M, Cangemi R, Pellini S, Mensah A, Albertini V, et al. ETS transcription factors control transcription of EZH2 and epigenetic silencing of the tumor suppressor gene Nkx3.1 in prostate cancer. PLoS ONE. 2010;5:e10547 pubmed publisher |
