| Published Application/Species/Sample/Dilution | Reference |
|---|
- flow cytometry; mouse; loading ...; fig 7b, 7f
| Li F, Zeng Z, Xing S, Gullicksrud J, Shan Q, Choi J, et al. Ezh2 programs TFH differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf. Nat Commun. 2018;9:5452 pubmed publisher |
- western blot; human; fig 1d
| Wu Y, Zhang Z, Cenciarini M, Proietti C, Amasino M, Hong T, et al. Tamoxifen Resistance in Breast Cancer Is Regulated by the EZH2-ERα-GREB1 Transcriptional Axis. Cancer Res. 2018;78:671-684 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 1a
- western blot; human; 1:1000; loading ...; fig 3a
| Lu W, Liu S, Li B, Xie Y, Izban M, Ballard B, et al. SKP2 loss destabilizes EZH2 by promoting TRAF6-mediated ubiquitination to suppress prostate cancer. Oncogene. 2017;36:1364-1373 pubmed publisher |
- flow cytometry; human; fig 1
| Zhao E, Maj T, Kryczek I, Li W, Wu K, Zhao L, et al. Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction. Nat Immunol. 2016;17:95-103 pubmed publisher |
- immunohistochemistry; mouse; 1:100; fig 1b
| Khan M, Walters L, Li Q, Thomas D, Miller J, Zhang Q, et al. Characterization and pharmacologic targeting of EZH2, a fetal retinal protein and epigenetic regulator, in human retinoblastoma. Lab Invest. 2015;95:1278-90 pubmed publisher |
- western blot; human; loading ...; fig 2a
| Navarro J, Touzart A, Pradel L, Loosveld M, Koubi M, Fenouil R, et al. Site- and allele-specific polycomb dysregulation in T-cell leukaemia. Nat Commun. 2015;6:6094 pubmed publisher |
- ChIP-Seq; human; fig s7
- western blot; human; fig 6
| Xu J, Shao Z, Li D, Xie H, Kim W, Huang J, et al. Developmental control of polycomb subunit composition by GATA factors mediates a switch to non-canonical functions. Mol Cell. 2015;57:304-316 pubmed publisher |
- western blot; rat; 1:1000; fig 2
| Liu J, Magri L, Zhang F, Marsh N, Albrecht S, Huynh J, et al. Chromatin landscape defined by repressive histone methylation during oligodendrocyte differentiation. J Neurosci. 2015;35:352-65 pubmed publisher |
- immunohistochemistry - paraffin section; human; loading ...; fig 6b
- chromatin immunoprecipitation; human; loading ...; fig 4d
- western blot; human; loading ...; fig 4b
| Takayama K, Suzuki T, Tsutsumi S, Fujimura T, Urano T, Takahashi S, et al. RUNX1, an androgen- and EZH2-regulated gene, has differential roles in AR-dependent and -independent prostate cancer. Oncotarget. 2015;6:2263-76 pubmed |
- immunocytochemistry; mouse
| Zhou Q, Guo Y, Zheng B, Shao B, Jiang M, Wang G, et al. Establishment of a proteome profile and identification of molecular markers for mouse spermatogonial stem cells. J Cell Mol Med. 2015;19:521-34 pubmed publisher |
| Zhuang Y, Nguyen H, Burow M, Zhuo Y, El Dahr S, Yao X, et al. Elevated expression of long intergenic non-coding RNA HOTAIR in a basal-like variant of MCF-7 breast cancer cells. Mol Carcinog. 2015;54:1656-67 pubmed publisher |
- western blot; human; fig 5
| Van der Meulen J, Sanghvi V, Mavrakis K, Durinck K, Fang F, Matthijssens F, et al. The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia. Blood. 2015;125:13-21 pubmed publisher |
| Karoopongse E, Yeung C, Byon J, Ramakrishnan A, Holman Z, Jiang P, et al. The KDM2B- let-7b -EZH2 axis in myelodysplastic syndromes as a target for combined epigenetic therapy. PLoS ONE. 2014;9:e107817 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:100
| Sparmann A, Xie Y, Verhoeven E, Vermeulen M, Lancini C, Gargiulo G, et al. The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation. EMBO J. 2013;32:1598-612 pubmed publisher |
- immunocytochemistry; mouse; 1:500
- western blot; mouse; 1:2000
| Sarma K, Levasseur P, Aristarkhov A, Lee J. Locked nucleic acids (LNAs) reveal sequence requirements and kinetics of Xist RNA localization to the X chromosome. Proc Natl Acad Sci U S A. 2010;107:22196-201 pubmed publisher |
| Chiang S, Chang W, Chen S, Chang L. DOCK1 Regulates Growth and Motility through the RRP1B-Claudin-1 Pathway in Claudin-Low Breast Cancer Cells. Cancers (Basel). 2019;11: pubmed publisher |
| Burr M, Sparbier C, Chan K, Chan Y, Kersbergen A, Lam E, et al. An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer. Cancer Cell. 2019;36:385-401.e8 pubmed publisher |
| Du J, Kirk B, Zeng J, Ma J, Wang Q. Three classes of response elements for human PRC2 and MLL1/2-Trithorax complexes. Nucleic Acids Res. 2018;46:8848-8864 pubmed publisher |
| Bitler B, Aird K, Garipov A, Li H, Amatangelo M, Kossenkov A, et al. Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers. Nat Med. 2015;21:231-8 pubmed publisher |
| Arvey A, van der Veeken J, Samstein R, Feng Y, Stamatoyannopoulos J, Rudensky A. Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cells. Nat Immunol. 2014;15:580-587 pubmed publisher |
| Ciarapica R, Carcarino E, Adesso L, De Salvo M, Bracaglia G, Leoncini P, et al. Pharmacological inhibition of EZH2 as a promising differentiation therapy in embryonal RMS. BMC Cancer. 2014;14:139 pubmed publisher |
| Toth Z, Brulois K, Lee H, Izumiya Y, Tepper C, Kung H, et al. Biphasic euchromatin-to-heterochromatin transition on the KSHV genome following de novo infection. PLoS Pathog. 2013;9:e1003813 pubmed publisher |
| Vella S, Gnani D, Crudele A, Ceccarelli S, De Stefanis C, Gaspari S, et al. EZH2 down-regulation exacerbates lipid accumulation and inflammation in in vitro and in vivo NAFLD. Int J Mol Sci. 2013;14:24154-68 pubmed publisher |
| Kaneko S, Son J, Shen S, Reinberg D, Bonasio R. PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells. Nat Struct Mol Biol. 2013;20:1258-64 pubmed publisher |
| Greussing R, Hackl M, Charoentong P, Pauck A, Monteforte R, Cavinato M, et al. Identification of microRNA-mRNA functional interactions in UVB-induced senescence of human diploid fibroblasts. BMC Genomics. 2013;14:224 pubmed publisher |
| Vanharanta S, Shu W, Brenet F, Hakimi A, Heguy A, Viale A, et al. Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer. Nat Med. 2013;19:50-6 pubmed publisher |
| Shin Y, Kim J. The role of EZH2 in the regulation of the activity of matrix metalloproteinases in prostate cancer cells. PLoS ONE. 2012;7:e30393 pubmed publisher |
| Hayashi S, Kumai T, Matsuda Y, Aoki N, Sato K, Kimura S, et al. Six-transmembrane epithelial antigen of the prostate and enhancer of zeste homolog 2 as immunotherapeutic targets for lung cancer. J Transl Med. 2011;9:191 pubmed publisher |
| Prensner J, Iyer M, Balbin O, Dhanasekaran S, Cao Q, Brenner J, et al. Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression. Nat Biotechnol. 2011;29:742-9 pubmed publisher |
| Toth Z, Maglinte D, Lee S, Lee H, Wong L, Brulois K, et al. Epigenetic analysis of KSHV latent and lytic genomes. PLoS Pathog. 2010;6:e1001013 pubmed publisher |
