product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
53BP1
catalog :
612522
quantity :
50 µg
price :
198.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
19/53BP1
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig 3a
  • immunohistochemistry; human; loading ...; fig 3a
Mirman Z, Lottersberger F, Takai H, Kibe T, Gong Y, Takai K, et al. 53BP1-RIF1-shieldin counteracts DSB resection through CST- and Polα-dependent fill-in. Nature. 2018;560:112-116 pubmed publisher
  • immunocytochemistry; human; 1:1000; loading ...; fig s4b
  • western blot; human; 1:1000; loading ...; fig s7c
Xu H, Di Antonio M, McKinney S, Mathew V, Ho B, O Neil N, et al. CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours. Nat Commun. 2017;8:14432 pubmed publisher
  • immunocytochemistry; human; 1:1000; loading ...; fig 4a
Kumari A, Owen N, Juarez E, McCullough A. BLM protein mitigates formaldehyde-induced genomic instability. DNA Repair (Amst). 2015;28:73-82 pubmed publisher
  • flow cytometry; mouse
Hu H, Wang B, Borde M, Nardone J, Maika S, Allred L, et al. Foxp1 is an essential transcriptional regulator of B cell development. Nat Immunol. 2006;7:819-26 pubmed
Byrum A, Carvajal Maldonado D, Mudge M, Valle García D, Majid M, Patel R, et al. Mitotic regulators TPX2 and Aurora A protect DNA forks during replication stress by counteracting 53BP1 function. J Cell Biol. 2019;218:422-432 pubmed publisher
Maachani U, Shankavaram U, Kramp T, Tofilon P, Camphausen K, Tandle A. FOXM1 and STAT3 interaction confers radioresistance in glioblastoma cells. Oncotarget. 2016;7:77365-77377 pubmed publisher
Leung J, Agarwal P, Canny M, Gong F, Robison A, Finkelstein I, et al. Nucleosome acidic patch promotes RNF168- and RING1B/BMI1-dependent H2AX and H2A ubiquitination and DNA damage signaling. PLoS Genet. 2014;10:e1004178 pubmed publisher
Vadnais C, Davoudi S, Afshin M, Harada R, Dudley R, Clermont P, et al. CUX1 transcription factor is required for optimal ATM/ATR-mediated responses to DNA damage. Nucleic Acids Res. 2012;40:4483-95 pubmed publisher
product information
Cat.# :
612522
Brand :
BD Transduction Laboratories
Name :
53BP1
Format :
Purified
Clone :
19/53BP1
Isotype :
Ms IgG 2b
React :
Hu
Conc :
250 µg/ml
Apps :
Bioimg , WB
Size :
50 µg
Status :
RUO
List Price :
198.00 USD
more info or order :
company information