product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Stat3 pY705
catalog :
612357
quantity :
150 µg
price :
490.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4/P-STAT3
reactivity :
human, mouse
application :
western blot, immunocytochemistry, flow cytometry
more info or order :
citations: 17
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 3a
van Andel H, Ren Z, Koopmans I, Joosten S, Kocemba K, de Lau W, et al. Aberrantly expressed LGR4 empowers Wnt signaling in multiple myeloma by hijacking osteoblast-derived R-spondins. Proc Natl Acad Sci U S A. 2017;114:376-381 pubmed publisher
  • flow cytometry; mouse; 1:25; fig 2
  • flow cytometry; human; 1:25; fig 1h
Wan C, Li P, Spolski R, Oh J, Andraski A, Du N, et al. IL-21-mediated non-canonical pathway for IL-1β production in conventional dendritic cells. Nat Commun. 2015;6:7988 pubmed publisher
  • flow cytometry; human; loading ...; fig 2a
Rasmussen T, Andersen T, Bak R, Yiu G, Sørensen C, Stengaard Pedersen K, et al. Overexpression of microRNA-155 increases IL-21 mediated STAT3 signaling and IL-21 production in systemic lupus erythematosus. Arthritis Res Ther. 2015;17:154 pubmed publisher
  • western blot; mouse; fig 6
  • western blot; human; fig 6
Hernández P, Mahlakõiv T, Yang I, Schwierzeck V, Nguyen N, Guendel F, et al. Interferon-λ and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infection. Nat Immunol. 2015;16:698-707 pubmed publisher
  • flow cytometry; mouse; fig s5
Shrestha S, Yang K, Guy C, Vogel P, Neale G, Chi H. Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses. Nat Immunol. 2015;16:178-87 pubmed publisher
Kim J, Kim S, Park J, Hwang S, Choi J, Jung K, et al. Metformin improves salivary gland inflammation and hypofunction in murine Sjögren's syndrome. Arthritis Res Ther. 2019;21:136 pubmed publisher
Lun X, Szklarczyk D, Gábor A, Dobberstein N, Zanotelli V, Saez Rodriguez J, et al. Analysis of the Human Kinome and Phosphatome by Mass Cytometry Reveals Overexpression-Induced Effects on Cancer-Related Signaling. Mol Cell. 2019;74:1086-1102.e5 pubmed publisher
Shastri A, Choudhary G, Teixeira M, Gordon Mitchell S, Ramachandra N, Bernard L, et al. Antisense STAT3 inhibitor decreases viability of myelodysplastic and leukemic stem cells. J Clin Invest. 2018;128:5479-5488 pubmed publisher
Niu Q, Huang Z, Wu X, Jin Y, An Y, Li Y, et al. Enhanced IL-6/phosphorylated STAT3 signaling is related to the imbalance of circulating T follicular helper/T follicular regulatory cells in patients with rheumatoid arthritis. Arthritis Res Ther. 2018;20:200 pubmed publisher
Deason K, Troutman T, Jain A, Challa D, Mandraju R, Brewer T, et al. BCAP links IL-1R to the PI3K-mTOR pathway and regulates pathogenic Th17 cell differentiation. J Exp Med. 2018;215:2413-2428 pubmed publisher
Davies R, Hammenfors D, Bergum B, Vogelsang P, Gavasso S, Brun J, et al. Aberrant cell signalling in PBMCs upon IFN-α stimulation in primary Sjögren's syndrome patients associates with type I interferon signature. Eur J Immunol. 2018;48:1217-1227 pubmed publisher
Maseda D, Johnson E, Nyhoff L, Baron B, Kojima F, Wilhelm A, et al. mPGES1-Dependent Prostaglandin E2 (PGE2) Controls Antigen-Specific Th17 and Th1 Responses by Regulating T Autocrine and Paracrine PGE2 Production. J Immunol. 2018;200:725-736 pubmed publisher
Noel J, Ramser B, Cancelas J, McCormack F, Gardner J. Thermal injury of the skin induces G-CSF-dependent attenuation of EPO-mediated STAT signaling and erythroid differentiation arrest in mice. Exp Hematol. 2017;56:16-30 pubmed publisher
Schwerd T, Twigg S, Aschenbrenner D, Manrique S, Miller K, Taylor I, et al. A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis. J Exp Med. 2017;214:2547-2562 pubmed publisher
Brahmakshatriya V, Kuang Y, Devarajan P, Xia J, Zhang W, Vong A, et al. IL-6 Production by TLR-Activated APC Broadly Enhances Aged Cognate CD4 Helper and B Cell Antibody Responses In Vivo. J Immunol. 2017;198:2819-2833 pubmed publisher
Pahari S, Khan N, Aqdas M, Negi S, Kaur J, Agrewala J. Infergen Stimulated Macrophages Restrict Mycobacterium tuberculosis Growth by Autophagy and Release of Nitric Oxide. Sci Rep. 2016;6:39492 pubmed publisher
Anderson A, Pratt A, Sedhom M, Doran J, Routledge C, Hargreaves B, et al. IL-6-driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anticitrullinated peptide antibody-negative rheumatoid arthritis. Ann Rheum Dis. 2016;75:466-73 pubmed publisher
product information
Cat.# :
612357
Brand :
BD Transduction Laboratories
Name :
Stat3 pY705
Format :
Purified
Clone :
4/P-STAT3
Isotype :
Ms IgG 2a
React :
Hu , Ms
Conc :
250 µg/ml
Apps :
IC/FCM , WB
Size :
150 µg
Status :
RUO
List Price :
490.00 USD
more info or order :
company information