product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Tom20
catalog :
612278
quantity :
50 µg
price :
207.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
29/Tom20
reactivity :
African green monkey, human, mouse, rat, dogs
application :
western blot, immunocytochemistry
more info or order :
citations: 30
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:200; loading ...; fig 3c
  • western blot; human; 1:1000; loading ...; fig 3s1a
Yeshaw W, van der Zwaag M, Pinto F, Lahaye L, Faber A, Gómez Sánchez R, et al. Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility. elife. 2019;8: pubmed publisher
  • western blot; human; loading ...; fig 6a
Goiran T, Duplan E, Rouland L, El Manaa W, Lauritzen I, Dunys J, et al. Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation. Cell Death Differ. 2018;25:873-884 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 1c
  • western blot; human; 1:1000; loading ...; fig s2a
Jimenez Orgaz A, Kvainickas A, Nägele H, Denner J, Eimer S, Dengjel J, et al. Control of RAB7 activity and localization through the retromer-TBC1D5 complex enables RAB7-dependent mitophagy. EMBO J. 2018;37:235-254 pubmed publisher
  • immunocytochemistry; African green monkey; 1:5000; loading ...
Newman L, Schiavon C, Zhou C, Kahn R. The abundance of the ARL2 GTPase and its GAP, ELMOD2, at mitochondria are modulated by the fusogenic activity of mitofusins and stressors. PLoS ONE. 2017;12:e0175164 pubmed publisher
  • immunocytochemistry; human; fig s12
Yi J, Manna A, Barr V, Hong J, Neuman K, Samelson L. madSTORM: a superresolution technique for large-scale multiplexing at single-molecule accuracy. Mol Biol Cell. 2016;27:3591-3600 pubmed
  • western blot; mouse; fig 4
  • western blot; human; fig 1
Zhuang H, Tian W, Li W, Zhang X, Wang J, Yang Y, et al. Autophagic Cell Death and Apoptosis Jointly Mediate Cisatracurium Besylate-Induced Cell Injury. Int J Mol Sci. 2016;17:515 pubmed publisher
  • western blot; human; 1:1000; fig 5
Marnef A, Jády B, Kiss T. Human polypyrimidine tract-binding protein interacts with mitochondrial tRNA(Thr) in the cytosol. Nucleic Acids Res. 2016;44:1342-53 pubmed publisher
  • western blot; African green monkey; 1:1000; loading ...; fig 2b
Nava C, Rupp J, Boissel J, Mignot C, Rastetter A, Amiet C, et al. Hypomorphic variants of cationic amino acid transporter 3 in males with autism spectrum disorders. Amino Acids. 2015;47:2647-58 pubmed publisher
  • immunocytochemistry; rat; fig 1a
Wang C, Du W, Su Q, Zhu M, Feng P, Li Y, et al. Dynamic tubulation of mitochondria drives mitochondrial network formation. Cell Res. 2015;25:1108-20 pubmed publisher
  • western blot; human; fig  3
Zou J, Li W, Misra A, Yue F, Song K, Chen Q, et al. The viral restriction factor tetherin prevents leucine-rich pentatricopeptide repeat-containing protein (LRPPRC) from association with beclin 1 and B-cell CLL/lymphoma 2 (Bcl-2) and enhances autophagy and mitophagy. J Biol Chem. 2015;290:7269-79 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 3
Wanet A, Remacle N, Najar M, Sokal E, Arnould T, Najimi M, et al. Mitochondrial remodeling in hepatic differentiation and dedifferentiation. Int J Biochem Cell Biol. 2014;54:174-85 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
Zou J, Yue F, Li W, Song K, Jiang X, Yi J, et al. Autophagy inhibitor LRPPRC suppresses mitophagy through interaction with mitophagy initiator Parkin. PLoS ONE. 2014;9:e94903 pubmed publisher
  • western blot; human; fig 4
Li W, Zhang X, Zhuang H, Chen H, Chen Y, Tian W, et al. MicroRNA-137 is a novel hypoxia-responsive microRNA that inhibits mitophagy via regulation of two mitophagy receptors FUNDC1 and NIX. J Biol Chem. 2014;289:10691-701 pubmed publisher
  • western blot; mouse
Baseler W, Dabkowski E, Jagannathan R, Thapa D, Nichols C, Shepherd D, et al. Reversal of mitochondrial proteomic loss in Type 1 diabetic heart with overexpression of phospholipid hydroperoxide glutathione peroxidase. Am J Physiol Regul Integr Comp Physiol. 2013;304:R553-65 pubmed publisher
Gillingham A, Bertram J, Begum F, Munro S. In vivo identification of GTPase interactors by mitochondrial relocalization and proximity biotinylation. elife. 2019;8: pubmed publisher
Almada P, Pereira P, Culley S, Caillol G, Boroni Rueda F, Dix C, et al. Automating multimodal microscopy with NanoJ-Fluidics. Nat Commun. 2019;10:1223 pubmed publisher
Zheng P, Chen Q, Tian X, Qian N, Chai P, Liu B, et al. DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling. Cell Res. 2018;28:833-854 pubmed publisher
Itoh K, Adachi Y, Yamada T, Suzuki T, Otomo T, McBride H, et al. A brain-enriched Drp1 isoform associates with lysosomes, late endosomes, and the plasma membrane. J Biol Chem. 2018;293:11809-11822 pubmed publisher
Vannocci T, Notario Manzano R, Beccalli O, Bettegazzi B, Grohovaz F, Cinque G, et al. Adding a temporal dimension to the study of Friedreich's ataxia: the effect of frataxin overexpression in a human cell model. Dis Model Mech. 2018;11: pubmed publisher
Wong Y, Ysselstein D, Krainc D. Mitochondria-lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis. Nature. 2018;554:382-386 pubmed publisher
Kumar A, Shaha C. SESN2 facilitates mitophagy by helping Parkin translocation through ULK1 mediated Beclin1 phosphorylation. Sci Rep. 2018;8:615 pubmed publisher
Yang Z, Zhao X, Xu J, Shang W, Tong C. A novel fluorescent reporter detects plastic remodeling of mitochondria-ER contact sites. J Cell Sci. 2018;131: pubmed publisher
Ito S, Asakura M, Liao Y, Min K, Takahashi A, Shindo K, et al. Identification of the Mtus1 Splice Variant as a Novel Inhibitory Factor Against Cardiac Hypertrophy. J Am Heart Assoc. 2016;5: pubmed publisher
Cullen J, Abdul Murad N, Yeo A, McKenzie M, Ward M, Chong K, et al. AarF Domain Containing Kinase 3 (ADCK3) Mutant Cells Display Signs of Oxidative Stress, Defects in Mitochondrial Homeostasis and Lysosomal Accumulation. PLoS ONE. 2016;11:e0148213 pubmed publisher
Ma J, Meng F, Li S, Liu L, Zhao L, Liu Y, et al. Autophagy Induction by Endothelial-Monocyte Activating Polypeptide II Contributes to the Inhibition of Malignant Biological Behaviors by the Combination of EMAP II with Rapamycin in Human Glioblastoma. Front Mol Neurosci. 2015;8:74 pubmed publisher
Wang W, Wang X, Fujioka H, Hoppel C, Whone A, Caldwell M, et al. Parkinson's disease-associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes. Nat Med. 2016;22:54-63 pubmed publisher
Westrate L, Drocco J, Martin K, Hlavacek W, Mackeigan J. Mitochondrial morphological features are associated with fission and fusion events. PLoS ONE. 2014;9:e95265 pubmed publisher
Macvicar T, Lane J. Impaired OMA1-dependent cleavage of OPA1 and reduced DRP1 fission activity combine to prevent mitophagy in cells that are dependent on oxidative phosphorylation. J Cell Sci. 2014;127:2313-25 pubmed publisher
Zou J, Yue F, Jiang X, Li W, Yi J, Liu L. Mitochondrion-associated protein LRPPRC suppresses the initiation of basal levels of autophagy via enhancing Bcl-2 stability. Biochem J. 2013;454:447-57 pubmed publisher
Fricker M, O Prey J, Tolkovsky A, Ryan K. Phosphorylation of Puma modulates its apoptotic function by regulating protein stability. Cell Death Dis. 2010;1:e59 pubmed publisher
product information
Cat.# :
612278
Brand :
BD Transduction Laboratories
Name :
Tom20
Format :
Purified
Clone :
29/Tom20
Isotype :
Ms IgG 1
React :
Hu , Rat , Dog
Conc :
250 µg/ml
Apps :
IF , WB
Size :
50 µg
Status :
RUO
List Price :
207.00 USD
more info or order :
company information