product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Stat5 pY694
catalog :
611964
quantity :
50 µg
price :
288.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
47/Stat5
reactivity :
human, mouse
application :
western blot, immunocytochemistry, flow cytometry
more info or order :
citations: 21
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 4c
Gorvel L, Korenfeld D, Tung T, Klechevsky E. Dendritic Cell-Derived IL-32?: A Novel Inhibitory Cytokine of NK Cell Function. J Immunol. 2017;199:1290-1300 pubmed publisher
  • flow cytometry; human; loading ...; fig s18a
Kagoya Y, Nakatsugawa M, Yamashita Y, Ochi T, Guo T, Anczurowski M, et al. BET bromodomain inhibition enhances T cell persistence and function in adoptive immunotherapy models. J Clin Invest. 2016;126:3479-94 pubmed publisher
  • western blot; mouse; 1:5000
McDonald P, Read K, Baker C, Anderson A, Powell M, Ballesteros Tato A, et al. IL-7 signalling represses Bcl-6 and the TFH gene program. Nat Commun. 2016;7:10285 pubmed publisher
  • western blot; human; fig s7
Goodman C, Sato T, Peck A, Girondo M, Yang N, Liu C, et al. Steroid induction of therapy-resistant cytokeratin-5-positive cells in estrogen receptor-positive breast cancer through a BCL6-dependent mechanism. Oncogene. 2016;35:1373-85 pubmed publisher
  • western blot; mouse; fig 6c
Krysiak K, Tibbitts J, Shao J, Liu T, Ndonwi M, Walter M. Reduced levels of Hspa9 attenuate Stat5 activation in mouse B cells. Exp Hematol. 2015;43:319-30.e10 pubmed publisher
  • western blot; mouse; fig 1
Chou C, Pinto A, Curtis J, Persaud S, Cella M, Lin C, et al. c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells. Nat Immunol. 2014;15:884-93 pubmed publisher
  • western blot; mouse; fig 2
Oestreich K, Mohn S, Weinmann A. Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile. Nat Immunol. 2012;13:405-11 pubmed publisher
  • western blot; human; fig 5
Modi H, Li L, Chu S, Rossi J, Yee J, Bhatia R. Inhibition of Grb2 expression demonstrates an important role in BCR-ABL-mediated MAPK activation and transformation of primary human hematopoietic cells. Leukemia. 2011;25:305-12 pubmed publisher
Labuhn M, Perkins K, Matzk S, Varghese L, Garnett C, Papaemmanuil E, et al. Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome. Cancer Cell. 2019;36:123-138.e10 pubmed publisher
Yang B, Wang K, Wan S, Liang Y, Yuan X, Dong Y, et al. TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune Diseases. Cell Rep. 2019;27:3629-3645.e6 pubmed publisher
Lun X, Szklarczyk D, Gábor A, Dobberstein N, Zanotelli V, Saez Rodriguez J, et al. Analysis of the Human Kinome and Phosphatome by Mass Cytometry Reveals Overexpression-Induced Effects on Cancer-Related Signaling. Mol Cell. 2019;74:1086-1102.e5 pubmed publisher
Mann E, Gabryšová L, Pfeffer P, O GARRA A, Hawrylowicz C. High-Dose IL-2 Skews a Glucocorticoid-Driven IL-17+IL-10+ Memory CD4+ T Cell Response towards a Single IL-10-Producing Phenotype. J Immunol. 2019;202:684-693 pubmed publisher
Fistonich C, Zehentmeier S, Bednarski J, Miao R, Schjerven H, Sleckman B, et al. Cell circuits between B cell progenitors and IL-7+ mesenchymal progenitor cells control B cell development. J Exp Med. 2018;215:2586-2599 pubmed publisher
Davies R, Hammenfors D, Bergum B, Vogelsang P, Gavasso S, Brun J, et al. Aberrant cell signalling in PBMCs upon IFN-α stimulation in primary Sjögren's syndrome patients associates with type I interferon signature. Eur J Immunol. 2018;48:1217-1227 pubmed publisher
Maseda D, Johnson E, Nyhoff L, Baron B, Kojima F, Wilhelm A, et al. mPGES1-Dependent Prostaglandin E2 (PGE2) Controls Antigen-Specific Th17 and Th1 Responses by Regulating T Autocrine and Paracrine PGE2 Production. J Immunol. 2018;200:725-736 pubmed publisher
Carpenter A, Wohlfert E, Chopp L, Vacchio M, Nie J, Zhao Y, et al. Control of Regulatory T Cell Differentiation by the Transcription Factors Thpok and LRF. J Immunol. 2017;199:1716-1728 pubmed publisher
Jeffery H, Jeffery L, Lutz P, Corrigan M, Webb G, Hirschfield G, et al. Low-dose interleukin-2 promotes STAT-5 phosphorylation, Treg survival and CTLA-4-dependent function in autoimmune liver diseases. Clin Exp Immunol. 2017;188:394-411 pubmed publisher
Cooley I, Read K, Oestreich K. Trans-presentation of IL-15 modulates STAT5 activation and Bcl-6 expression in TH1 cells. Sci Rep. 2015;5:15722 pubmed publisher
Berger A, Hoelbl Kovacic A, Bourgeais J, Hoefling L, Warsch W, Grundschober E, et al. PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis. Leukemia. 2014;28:629-41 pubmed publisher
Roll J, Reuther G. ALK-activating homologous mutations in LTK induce cellular transformation. PLoS ONE. 2012;7:e31733 pubmed publisher
Han L, Wierenga A, Rozenveld Geugien M, van de Lande K, Vellenga E, Schuringa J. Single-cell STAT5 signal transduction profiling in normal and leukemic stem and progenitor cell populations reveals highly distinct cytokine responses. PLoS ONE. 2009;4:e7989 pubmed publisher
product information
Cat.# :
611964
Brand :
BD Transduction Laboratories
Name :
Stat5 pY694
Format :
Purified
Clone :
47/Stat5(pY694
Isotype :
Ms IgG 1
React :
Hu
Conc :
250 µg/ml
Apps :
IC/FCM , WB
Size :
50 µg
Status :
RUO
List Price :
288.00 USD
more info or order :
company information