| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; human; fig 2
| Badia R, Pauls E, Riveira-Munoz E, Clotet B, Este J, Ballana E. Zinc finger endonuclease targeting PSIP1 inhibits HIV-1 integration. Antimicrob Agents Chemother. 2014;58:4318-27 pubmed publisher
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- immunocytochemistry; human; fig 1
- western blot; human; 1:500; fig 1
| Lopez A, Kugelman J, Garcia-Rivera J, Urias E, Salinas S, Fernandez-Zapico M, et al. The Structure-Specific Recognition Protein 1 Associates with Lens Epithelium-Derived Growth Factor Proteins and Modulates HIV-1 Replication. J Mol Biol. 2016;428:2814-31 pubmed publisher
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- western blot; human; fig 4
| Kanu N, Gronroos E, Martinez P, Burrell R, Yi Goh X, Bartkova J, et al. SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair. Oncogene. 2015;34:5699-708 pubmed publisher
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- western blot; human; 1:500
| Fadel H, Morrison J, Saenz D, Fuchs J, Kvaratskhelia M, Ekker S, et al. TALEN knockout of the PSIP1 gene in human cells: analyses of HIV-1 replication and allosteric integrase inhibitor mechanism. J Virol. 2014;88:9704-17 pubmed publisher
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- immunocytochemistry; human; 1:200
- western blot; human; 1:2000
| Morchikh M, Naughtin M, Di Nunzio F, Xavier J, Charneau P, Jacob Y, et al. TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication. PLoS ONE. 2013;8:e81217 pubmed publisher
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| Sharma A, Slaughter A, Jena N, Feng L, Kessl J, Fadel H, et al. A new class of multimerization selective inhibitors of HIV-1 integrase. PLoS Pathog. 2014;10:e1004171 pubmed publisher
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| Meehan A, Saenz D, Morrison J, Garcia-Rivera J, Peretz M, Llano M, et al. LEDGF/p75 proteins with alternative chromatin tethers are functional HIV-1 cofactors. PLoS Pathog. 2009;5:e1000522 pubmed publisher
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| Yan N, Cherepanov P, Daigle J, Engelman A, Lieberman J. The SET complex acts as a barrier to autointegration of HIV-1. PLoS Pathog. 2009;5:e1000327 pubmed publisher
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| Bhargavan B, Fatma N, Chhunchha B, Singh V, Kubo E, Singh D. LEDGF gene silencing impairs the tumorigenicity of prostate cancer DU145 cells by abating the expression of Hsp27 and activation of the Akt/ERK signaling pathway. Cell Death Dis. 2012;3:e316 pubmed publisher
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| Astiazaran P, Bueno M, Morales E, Kugelman J, Garcia-Rivera J, Llano M. HIV-1 integrase modulates the interaction of the HIV-1 cellular cofactor LEDGF/p75 with chromatin. Retrovirology. 2011;8:27 pubmed publisher
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