product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Tim23
catalog :
611222
quantity :
50 µg
price :
207.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
32/Tim23
reactivity :
African green monkey, human, mouse, rat, pig, baker's yeast
application :
western blot, immunocytochemistry
more info or order :
citations: 27
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 6a
Goiran T, Duplan E, Rouland L, El Manaa W, Lauritzen I, Dunys J, et al. Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation.. Cell Death Differ. 2018;0: pubmed publisher
  • immunocytochemistry; mouse; 1:100; loading ...; fig s1f
  • western blot; mouse; 1:1000; loading ...; fig s1e
Hammerling B, Najor R, Cortez M, Shires S, Leon L, Gonzalez E, et al. A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance. Nat Commun. 2017;8:14050 pubmed publisher
  • western blot; mouse; fig 1c
McLelland G, Lee S, McBride H, Fon E. Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system. J Cell Biol. 2016;214:275-91 pubmed publisher
  • western blot; human; loading ...; fig 8a
  • western blot; African green monkey; loading ...; fig 8a
Tábara L, Escalante R. VMP1 Establishes ER-Microdomains that Regulate Membrane Contact Sites and Autophagy. PLoS ONE. 2016;11:e0166499 pubmed publisher
  • western blot; baker's yeast; fig 1
Wrobel L, Sokol A, Chojnacka M, Chacinska A. The presence of disulfide bonds reveals an evolutionarily conserved mechanism involved in mitochondrial protein translocase assembly. Sci Rep. 2016;6:27484 pubmed publisher
  • western blot; mouse; fig s2
Schubert C, Raparelli V, Westphal C, Dworatzek E, Petrov G, Kararigas G, et al. Reduction of apoptosis and preservation of mitochondrial integrity under ischemia/reperfusion injury is mediated by estrogen receptor β. Biol Sex Differ. 2016;7:53 pubmed publisher
  • western blot; rat; 1:500; loading ...; fig 8b
de la Fuente S, Fernandez-Sanz C, Vail C, Agra E, Holmström K, Sun J, et al. Strategic Positioning and Biased Activity of the Mitochondrial Calcium Uniporter in Cardiac Muscle. J Biol Chem. 2016;291:23343-23362 pubmed
  • western blot; human; fig 1
  • western blot; mouse; fig 4
Zhuang H, Tian W, Li W, Zhang X, Wang J, Yang Y, et al. Autophagic Cell Death and Apoptosis Jointly Mediate Cisatracurium Besylate-Induced Cell Injury. Int J Mol Sci. 2016;17:515 pubmed publisher
  • western blot; human; loading ...; fig 2b
Cenini G, Rüb C, Bruderek M, Voos W. Amyloid β-peptides interfere with mitochondrial preprotein import competence by a coaggregation process. Mol Biol Cell. 2016;27:3257-3272 pubmed
  • western blot; rat; fig 4e
Wang C, Du W, Su Q, Zhu M, Feng P, Li Y, et al. Dynamic tubulation of mitochondria drives mitochondrial network formation. Cell Res. 2015;25:1108-20 pubmed publisher
  • western blot; mouse; loading ...; fig 1a
Zhang Q, Kuang H, Chen C, Yan J, Do-Umehara H, Liu X, et al. The kinase Jnk2 promotes stress-induced mitophagy by targeting the small mitochondrial form of the tumor suppressor ARF for degradation. Nat Immunol. 2015;16:458-66 pubmed publisher
  • western blot; pig; fig 4
Georgiannakis A, Burgoyne T, Lueck K, Futter C, Greenwood J, Moss S. Retinal Pigment Epithelial Cells Mitigate the Effects of Complement Attack by Endocytosis of C5b-9. J Immunol. 2015;195:3382-9 pubmed publisher
  • immunocytochemistry; mouse
  • western blot; mouse; fig 4
Tian W, Li W, Chen Y, Yan Z, Huang X, Zhuang H, et al. Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy. FEBS Lett. 2015;589:1847-54 pubmed publisher
  • western blot; human; 1:1000; fig 3
Sargsyan A, Cai J, Fandino L, Labasky M, Forostyan T, Colosimo L, et al. Rapid parallel measurements of macroautophagy and mitophagy in mammalian cells using a single fluorescent biosensor. Sci Rep. 2015;5:12397 pubmed publisher
  • western blot; human
Park S, Choi S, Yoo S, Nah J, Jeong E, Kim H, et al. Pyruvate stimulates mitophagy via PINK1 stabilization. Cell Signal. 2015;27:1824-30 pubmed publisher
  • western blot; mouse; fig 1, 6
Mauro-Lizcano M, Esteban-Martínez L, Seco E, Serrano-Puebla A, García-Ledo L, Figueiredo-Pereira C, et al. New method to assess mitophagy flux by flow cytometry. Autophagy. 2015;11:833-43 pubmed publisher
  • western blot; human; fig 5
Wang W, Wang Y, Chen H, Xing Y, Li F, Zhang Q, et al. Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway. Nat Chem Biol. 2014;10:133-40 pubmed publisher
  • western blot; human
Li W, Zhang X, Zhuang H, Chen H, Chen Y, Tian W, et al. MicroRNA-137 is a novel hypoxia-responsive microRNA that inhibits mitophagy via regulation of two mitophagy receptors FUNDC1 and NIX. J Biol Chem. 2014;289:10691-701 pubmed publisher
  • western blot; mouse
Baseler W, Dabkowski E, Jagannathan R, Thapa D, Nichols C, Shepherd D, et al. Reversal of mitochondrial proteomic loss in Type 1 diabetic heart with overexpression of phospholipid hydroperoxide glutathione peroxidase. Am J Physiol Regul Integr Comp Physiol. 2013;304:R553-65 pubmed publisher
  • western blot; human
Chaudhuri D, Sancak Y, Mootha V, Clapham D. MCU encodes the pore conducting mitochondrial calcium currents. elife. 2013;2:e00704 pubmed publisher
  • western blot; mouse
Tsika E, Glauser L, Moser R, Fiser A, Daniel G, Sheerin U, et al. Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration. Hum Mol Genet. 2014;23:4621-38 pubmed publisher
Cullen J, Abdul Murad N, Yeo A, McKenzie M, Ward M, Chong K, et al. AarF Domain Containing Kinase 3 (ADCK3) Mutant Cells Display Signs of Oxidative Stress, Defects in Mitochondrial Homeostasis and Lysosomal Accumulation. PLoS ONE. 2016;11:e0148213 pubmed publisher
Ma J, Meng F, Li S, Liu L, Zhao L, Liu Y, et al. Autophagy Induction by Endothelial-Monocyte Activating Polypeptide II Contributes to the Inhibition of Malignant Biological Behaviors by the Combination of EMAP II with Rapamycin in Human Glioblastoma. Front Mol Neurosci. 2015;8:74 pubmed publisher
Jezek J, Dlasková A, Zelenka J, Jaburek M, Jezek P. H₂O₂-Activated Mitochondrial Phospholipase iPLA₂γ Prevents Lipotoxic Oxidative Stress in Synergy with UCP2, Amplifies Signaling via G-Protein-Coupled Receptor GPR40, and Regulates Insulin Secretion in Pancreatic β-Cells. Antioxid Redox Signal. 2015;23:958-72 pubmed publisher
Guarani V, McNeill E, Paulo J, Huttlin E, Fröhlich F, Gygi S, et al. QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology. elife. 2015;4: pubmed publisher
Zhang Z, Wakabayashi N, Wakabayashi J, Tamura Y, Song W, Sereda S, et al. The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells. Mol Biol Cell. 2011;22:2235-45 pubmed publisher
Ljubicic V, Joseph A, Adhihetty P, Huang J, Saleem A, Uguccioni G, et al. Molecular basis for an attenuated mitochondrial adaptive plasticity in aged skeletal muscle. Aging (Albany NY). 2009;1:818-30 pubmed
product information
Cat.# :
611222
Brand :
BD Transduction Laboratories
Name :
Tim23
Format :
Purified
Clone :
32/Tim23
Isotype :
Ms IgG 2a
React :
Hu , Ms , Rat
Conc :
250 µg/ml
Apps :
IF , WB
Size :
50 µg
Status :
RUO
List Price :
207.00 USD
more info or order :
company information
BD Biosciences