product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
ALDH
catalog :
611194
quantity :
50 µg
price :
207.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
44/ALDH
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 18
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; loading ...; fig 1a
Zeng C, Weng C, Wang X, Yan Y, Li W, Xu D, et al. Functional Proteomics Identifies a PICS Complex Required for piRNA Maturation and Chromosome Segregation. Cell Rep. 2019;27:3561-3572.e3 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1a
Yasgar A, Titus S, Wang Y, Danchik C, Yang S, Vasiliou V, et al. A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity. PLoS ONE. 2017;12:e0170937 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 3a
Horimoto Y, Arakawa A, Sasahara N, Tanabe M, Sai S, Himuro T, et al. Combination of Cancer Stem Cell Markers CD44 and CD24 Is Superior to ALDH1 as a Prognostic Indicator in Breast Cancer Patients with Distant Metastases. PLoS ONE. 2016;11:e0165253 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 1A
Di Franco S, Turdo A, Benfante A, Colorito M, Gaggianesi M, Apuzzo T, et al. ?Np63 drives metastasis in breast cancer cells via PI3K/CD44v6 axis. Oncotarget. 2016;7:54157-54173 pubmed publisher
  • western blot; human; 1:1000; fig 4
Du L, LI Y, Fakih M, Wiatrek R, Duldulao M, Chen Z, et al. Role of SUMO activating enzyme in cancer stem cell maintenance and self-renewal. Nat Commun. 2016;7:12326 pubmed publisher
  • immunohistochemistry; human; 1:400; fig 1
Chene G, Ouellet V, Rahimi K, Barrès V, Meunier L, de Ladurantaye M, et al. Expression of Stem Cell Markers in Preinvasive Tubal Lesions of Ovarian Carcinoma. Biomed Res Int. 2015;2015:808531 pubmed publisher
  • immunohistochemistry; human; fig 3
Ruiz de Garibay G, Herranz C, Llorente A, Boni J, Serra Musach J, Mateo F, et al. Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness. PLoS ONE. 2015;10:e0132546 pubmed publisher
  • western blot; human; 1:1000; fig s10
Takahashi R, Miyazaki H, Takeshita F, Yamamoto Y, Minoura K, Ono M, et al. Loss of microRNA-27b contributes to breast cancer stem cell generation by activating ENPP1. Nat Commun. 2015;6:7318 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50; fig 1
  • immunocytochemistry; human; 1:50; fig 1
Honeth G, Lombardi S, Ginestier C, Hur M, Marlow R, Buchupalli B, et al. Aldehyde dehydrogenase and estrogen receptor define a hierarchy of cellular differentiation in the normal human mammary epithelium. Breast Cancer Res. 2014;16:R52 pubmed publisher
Sarvi S, Crispin R, Lu Y, Zeng L, Hurley T, Houston D, et al. ALDH1 Bio-activates Nifuroxazide to Eradicate ALDHHigh Melanoma-Initiating Cells. Cell Chem Biol. 2018;25:1456-1469.e6 pubmed publisher
Yang S, Martinez N, Yasgar A, Danchik C, Johansson C, Wang Y, et al. Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity. J Med Chem. 2018;61:4883-4903 pubmed publisher
Mateo F, Arenas E, Aguilar H, Serra Musach J, de Garibay G, Boni J, et al. Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition. Oncogene. 2017;36:2737-2749 pubmed publisher
Seo E, Kim D, Jang I, Choi E, Shin S, Lee S, et al. Hypoxia-NOTCH1-SOX2 signaling is important for maintaining cancer stem cells in ovarian cancer. Oncotarget. 2016;7:55624-55638 pubmed publisher
Choi E, Seo E, Kim D, Lee S, Kwon Y, Jang I, et al. FOXP1 functions as an oncogene in promoting cancer stem cell-like characteristics in ovarian cancer cells. Oncotarget. 2016;7:3506-19 pubmed publisher
Yan J, de Melo J, Cutz J, Aziz T, Tang D. Aldehyde dehydrogenase 3A1 associates with prostate tumorigenesis. Br J Cancer. 2014;110:2593-603 pubmed publisher
Fredebohm J, Boettcher M, Eisen C, Gaida M, Heller A, Keleg S, et al. Establishment and characterization of a highly tumourigenic and cancer stem cell enriched pancreatic cancer cell line as a well defined model system. PLoS ONE. 2012;7:e48503 pubmed publisher
Maddox J, Shakya A, South S, Shelton D, Andersen J, Chidester S, et al. Transcription factor Oct1 is a somatic and cancer stem cell determinant. PLoS Genet. 2012;8:e1003048 pubmed publisher
O Dwyer D, Ralton L, O Shea A, Murray G. The proteomics of colorectal cancer: identification of a protein signature associated with prognosis. PLoS ONE. 2011;6:e27718 pubmed publisher
product information
Cat.# :
611194
Brand :
BD Transduction Laboratories
Name :
ALDH
Format :
Purified
Clone :
44/ALDH
Isotype :
Ms IgG 1
React :
Hu
Conc :
250 µg/ml
Apps :
IF , WB
Size :
50 µg
Status :
RUO
List Price :
207.00 USD
more info or order :
company information