product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Hic-5
catalog :
611164
quantity :
50 µg
price :
207.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
34/Hic-5
reactivity :
human, mouse, rat, dog
application :
western blot, immunohistochemistry, immunocytochemistry, western blot knockout validation, immunohistochemistry knockout validation
more info or order :
BD Biosciences product webpage
citations: 10
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry knockout validation; mouse; loading ...; fig 1g
  • western blot knockout validation; mouse; loading ...; fig 1i
Goreczny G, Ouderkirk Pecone J, Olson E, Krendel M, Turner C. Hic-5 remodeling of the stromal matrix promotes breast tumor progression. Oncogene. 2017;36:2693-2703 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 1d
Rashid M, Belmont J, Carpenter D, Turner C, Olson E. Neural-specific deletion of the focal adhesion adaptor protein paxillin slows migration speed and delays cortical layer formation. Development. 2017;144:4002-4014 pubmed publisher
  • immunocytochemistry; rat; fig 1
Harizanova J, Fermin Y, Malik Sheriff R, Wieczorek J, Ickstadt K, Grecco H, et al. Highly Multiplexed Imaging Uncovers Changes in Compositional Noise within Assembling Focal Adhesions. PLoS ONE. 2016;11:e0160591 pubmed publisher
  • immunocytochemistry; human; fig 2
  • western blot; human; fig 1
Dave J, Abbey C, Duran C, Seo H, Johnson G, Bayless K. Hic-5 mediates the initiation of endothelial sprouting by regulating a key surface metalloproteinase. J Cell Sci. 2016;129:743-56 pubmed publisher
  • western blot; human; fig 1
Fujikawa A, Matsumoto M, Kuboyama K, Suzuki R, Noda M. Specific dephosphorylation at tyr-554 of git1 by ptprz promotes its association with paxillin and hic-5. PLoS ONE. 2015;10:e0119361 pubmed publisher
  • western blot; rat; 1:5000
Liu F, Wang X, Hu G, Wang Y, Zhou J. The transcription factor TEAD1 represses smooth muscle-specific gene expression by abolishing myocardin function. J Biol Chem. 2014;289:3308-16 pubmed publisher
  • immunohistochemistry; human
  • western blot; human
Croke J, Pike L, MacPhee D. The focal adhesion protein Hic-5 is highly expressed in the rat myometrium during late pregnancy and labour and co-localizes with FAK. Reprod Biol Endocrinol. 2007;5:22 pubmed
Goreczny G, Forsythe I, Turner C. Hic-5 regulates fibrillar adhesion formation to control tumor extracellular matrix remodeling through interaction with tensin1. Oncogene. 2018;37:1699-1713 pubmed publisher
Ryan P, Kales S, Yadavalli R, Nau M, Zhang H, Lipkowitz S. Cbl-c ubiquitin ligase activity is increased via the interaction of its RING finger domain with a LIM domain of the paxillin homolog, Hic 5. PLoS ONE. 2012;7:e49428 pubmed publisher
Costello I, Biondi C, Taylor J, Bikoff E, Robertson E. Smad4-dependent pathways control basement membrane deposition and endodermal cell migration at early stages of mouse development. BMC Dev Biol. 2009;9:54 pubmed publisher
product information
Cat.# :
611164
Brand :
BD Transduction Laboratories
Name :
Hic-5
Format :
Purified
Clone :
34/Hic-5
Isotype :
Ms IgG 1
React :
Hu , Ms , Rat , Dog
Conc :
250 µg/ml
Apps :
IF , WB
Size :
50 µg
Status :
RUO
List Price :
207.00 USD
more info or order :
BD Biosciences product webpage
company information