product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
PKA C
catalog :
610980
quantity :
50 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5B
reactivity :
human, mouse, rat, dogs
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section, other, western blot knockout validation
more info or order :
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; 1:1000; loading ...; fig 3b
Smith F, Esseltine J, Nygren P, Veesler D, Byrne D, Vonderach M, et al. Local protein kinase A action proceeds through intact holoenzymes. Science. 2017;356:1288-1293 pubmed publisher
  • immunocytochemistry; human; 1:5000; loading ...; fig 2a
  • western blot; human; 1:5000; loading ...; fig 3e
Arveseth C, Happ J, Hedeen D, Zhu J, Capener J, Klatt Shaw D, et al. Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits. PLoS Biol. 2021;19:e3001191 pubmed publisher
  • western blot; human; 1 ug/ml; fig 5j
Brzezinska P, Simpson N, Hubert F, Jacobs A, Umana M, MacKeil J, et al. Phosphodiesterase 1C integrates store-operated calcium entry and cAMP signaling in leading-edge protrusions of migrating human arterial myocytes. J Biol Chem. 2021;296:100606 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:1000; fig 1a
  • western blot; human; 1:1000; fig 2a
Weigand I, Ronchi C, Rizk Rabin M, Dalmazi G, Wild V, Bathon K, et al. Differential expression of the protein kinase A subunits in normal adrenal glands and adrenocortical adenomas. Sci Rep. 2017;7:49 pubmed publisher
  • other; human; loading ...; fig st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  • western blot; human; fig 3
Gerbaud P, Taskén K, Pidoux G. Spatiotemporal regulation of cAMP signaling controls the human trophoblast fusion. Front Pharmacol. 2015;6:202 pubmed publisher
  • western blot; mouse; 1:1000; fig 4e
Rajan S, Dickson L, Mathew E, Orr C, Ellenbroek J, Philipson L, et al. Chronic hyperglycemia downregulates GLP-1 receptor signaling in pancreatic β-cells via protein kinase A. Mol Metab. 2015;4:265-76 pubmed publisher
  • western blot; human; 1:4000
Calebiro D, Hannawacker A, Lyga S, Bathon K, Zabel U, Ronchi C, et al. PKA catalytic subunit mutations in adrenocortical Cushing's adenoma impair association with the regulatory subunit. Nat Commun. 2014;5:5680 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:1000; fig 3
  • western blot; human; fig 2
Moody S, Schinzel A, Singh S, Izzo F, Strickland M, Luo L, et al. PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling. Oncogene. 2015;34:2061-71 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
  • western blot; mouse; fig 1
Martin S, Fernandez Rojo M, Stanley A, Bastiani M, Okano S, Nixon S, et al. Caveolin-1 deficiency leads to increased susceptibility to cell death and fibrosis in white adipose tissue: characterization of a lipodystrophic model. PLoS ONE. 2012;7:e46242 pubmed publisher
Bizet A, Becker Heck A, Ryan R, Weber K, Filhol E, Krug P, et al. Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization. Nat Commun. 2015;6:8666 pubmed publisher
Sigloch F, Burk U, Biniossek M, Brabletz T, Schilling O. miR-200c dampens cancer cell migration via regulation of protein kinase A subunits. Oncotarget. 2015;6:23874-89 pubmed
Garcia Alvarez G, Lu B, Yap K, Wong L, Thevathasan J, Lim L, et al. STIM2 regulates PKA-dependent phosphorylation and trafficking of AMPARs. Mol Biol Cell. 2015;26:1141-59 pubmed publisher
product information
Cat.# :
610980
Brand :
BD Transduction Laboratories
Name :
PKA C
Format :
Purified
Clone :
5B
Isotype :
Ms IgG 2b
React :
Hu , Ms , Rat , Dog
Conc :
250 µg/ml
Apps :
IF , WB
Size :
50 µg
Status :
RUO
more info or order :
company information