product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
BiP
catalog :
610979
quantity :
150 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
40/BiP
reactivity :
human, mouse, rat, dogs, pigs
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry
more info or order :
citations: 27
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig s6b
Zhu J, Pittman S, Dhavale D, French R, Patterson J, Kaleelurrrahuman M, et al. VCP suppresses proteopathic seeding in neurons. Mol Neurodegener. 2022;17:30 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 5f
  • western blot; human; 1:1000; loading ...; fig 4f
Lebeau P, Byun J, Platko K, Saliba P, Sguazzin M, Macdonald M, et al. Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance. Nat Commun. 2022;13:770 pubmed publisher
  • western blot; mouse; loading ...; fig 6f
Wani A, Zhu J, ULRICH J, Eteleeb A, Sauerbeck A, Reitz S, et al. Neuronal VCP loss of function recapitulates FTLD-TDP pathology. Cell Rep. 2021;36:109399 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1c
Jang I, Pottekat A, Poothong J, Yong J, Lagunas Acosta J, Charbono A, et al. PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity. elife. 2019;8: pubmed publisher
  • western blot; human; loading ...; fig 5a
  • western blot; mouse; loading ...; fig 1m
Zhao Y, Chen Y, Miao G, Zhao H, Qu W, Li D, et al. The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation. Mol Cell. 2017;67:974-989.e6 pubmed publisher
  • western blot; mouse; 1:5000; loading ...
Cao L, Riascos Bernal D, Chinnasamy P, Dunaway C, Hou R, Pujato M, et al. Control of mitochondrial function and cell growth by the atypical cadherin Fat1. Nature. 2016;539:575-578 pubmed publisher
  • flow cytometry; human; 1:100; fig 3
Gebremariam T, Lin L, Liu M, Kontoyiannis D, French S, Edwards J, et al. Bicarbonate correction of ketoacidosis alters host-pathogen interactions and alleviates mucormycosis. J Clin Invest. 2016;126:2280-94 pubmed publisher
  • western blot; mouse; 1:10,000; fig 6
Jones F, Bailey M, Murray L, Lu Y, McNeilly S, Schlötzer Schrehardt U, et al. ER stress and basement membrane defects combine to cause glomerular and tubular renal disease resulting from Col4a1 mutations in mice. Dis Model Mech. 2016;9:165-76 pubmed publisher
  • western blot; mouse; fig 2c
Ito S, Nagata K. Mutants of collagen-specific molecular chaperone Hsp47 causing osteogenesis imperfecta are structurally unstable with weak binding affinity to collagen. Biochem Biophys Res Commun. 2016;469:437-42 pubmed publisher
  • western blot; mouse; fig 3
Wang J, Lu R, Yang J, Li H, He Z, Jing N, et al. TRPC6 specifically interacts with APP to inhibit its cleavage by γ-secretase and reduce Aβ production. Nat Commun. 2015;6:8876 pubmed publisher
  • immunocytochemistry; human; fig 4
  • western blot; human; fig 4
Adomako A, Calvo V, Biran N, Osman K, Chari A, Paton J, et al. Identification of markers that functionally define a quiescent multiple myeloma cell sub-population surviving bortezomib treatment. BMC Cancer. 2015;15:444 pubmed publisher
  • western blot; mouse
Van B, Nishi M, Komazaki S, Ichimura A, Kakizawa S, Nakanaga K, et al. Mitsugumin 56 (hedgehog acyltransferase-like) is a sarcoplasmic reticulum-resident protein essential for postnatal muscle maturation. FEBS Lett. 2015;589:1095-104 pubmed publisher
  • western blot; human; 1:1000; fig 7
Honegger A, Schilling D, Bastian S, Sponagel J, Kuryshev V, Sultmann H, et al. Dependence of intracellular and exosomal microRNAs on viral E6/E7 oncogene expression in HPV-positive tumor cells. PLoS Pathog. 2015;11:e1004712 pubmed publisher
  • immunoprecipitation; human; loading ...; fig 3
  • western blot; human; loading ...; fig 1c
  • immunoprecipitation; pigs ; loading ...; fig 3
  • western blot; pigs ; loading ...; fig 1d,3
Betzer C, Movius A, Shi M, Gai W, Zhang J, Jensen P. Identification of synaptosomal proteins binding to monomeric and oligomeric α-synuclein. PLoS ONE. 2015;10:e0116473 pubmed publisher
  • western blot; rat; fig 1
  • western blot; mouse; fig s1
Wang S, Park S, Kodali V, Han J, Yip T, Chen Z, et al. Identification of protein disulfide isomerase 1 as a key isomerase for disulfide bond formation in apolipoprotein B100. Mol Biol Cell. 2015;26:594-604 pubmed publisher
Eyking A, Ferber F, Köhler S, Reis H, Cario E. TRIM58 Restrains Intestinal Mucosal Inflammation by Negatively Regulating TLR2 in Myeloid Cells. J Immunol. 2019;203:1636-1649 pubmed publisher
Fang C, Kuo H, Hsu S, Yih L. HSP70 is required for the proper assembly of pericentriolar material and function of mitotic centrosomes. Cell Div. 2019;14:4 pubmed publisher
Zavodszky E, Hegde R. Misfolded GPI-anchored proteins are escorted through the secretory pathway by ER-derived factors. elife. 2019;8: pubmed publisher
Sundaram A, Appathurai S, Plumb R, Mariappan M. Dynamic changes in complexes of IRE1α, PERK, and ATF6α during endoplasmic reticulum stress. Mol Biol Cell. 2018;29:1376-1388 pubmed publisher
Wang X, Bi X, Zhang G, Deng Y, Luo X, Xu L, et al. Glucose-regulated protein 78 is essential for cardiac myocyte survival. Cell Death Differ. 2018;25:2181-2194 pubmed publisher
Zhao Y, Liu N, Miao G, Chen Y, Zhao H, Zhang H. The ER Contact Proteins VAPA/B Interact with Multiple Autophagy Proteins to Modulate Autophagosome Biogenesis. Curr Biol. 2018;28:1234-1245.e4 pubmed publisher
Lebeau P, Platko K, Al Hashimi A, Byun J, Lhotak S, Holzapfel N, et al. Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained. J Biol Chem. 2018;293:7329-7343 pubmed publisher
Dupuis Maurin V, Brinza L, Baguet J, Plantamura E, Schicklin S, Chambion S, et al. Overexpression of the transcription factor Sp1 activates the OAS-RNAse L-RIG-I pathway. PLoS ONE. 2015;10:e0118551 pubmed publisher
Drevinge C, Karlsson L, Ståhlman M, Larsson T, Perman Sundelin J, Grip L, et al. Cholesteryl esters accumulate in the heart in a porcine model of ischemia and reperfusion. PLoS ONE. 2013;8:e61942 pubmed publisher
Fowler S, Akins M, Zhou H, Figeys D, Bennett S. The liver connexin32 interactome is a novel plasma membrane-mitochondrial signaling nexus. J Proteome Res. 2013;12:2597-610 pubmed publisher
Ohshima K, Inoue K, Fujiwara A, Hatakeyama K, Kanto K, Watanabe Y, et al. Let-7 microRNA family is selectively secreted into the extracellular environment via exosomes in a metastatic gastric cancer cell line. PLoS ONE. 2010;5:e13247 pubmed publisher
Scriven P, Coulson S, Haines R, Balasubramanian S, Cross S, Wyld L. Activation and clinical significance of the unfolded protein response in breast cancer. Br J Cancer. 2009;101:1692-8 pubmed publisher
product information
Cat.# :
610979
Brand :
BD Transduction Laboratories
Name :
BiP
Format :
Purified
Clone :
40/BiP
Isotype :
Ms IgG 2a
React :
Hu , Ms , Rat , Dog
Conc :
250 µg/ml
Apps :
WB
Size :
150 µg
Status :
RUO
more info or order :
company information