product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
BiP
catalog :
610978
quantity :
50 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
40/BiP
reactivity :
African green monkey, human, mouse, rat, dogs, pigs
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, other
more info or order :
citations: 42
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 2f
Prater M, Hamilton R, Wa Yung H, Sharkey A, Robson P, Abd Hamid N, et al. RNA-Seq reveals changes in human placental metabolism, transport and endocrinology across the first-second trimester transition. Biol Open. 2021;10: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1g
Tripathi P, Guo H, Dreser A, Yamoah A, Sechi A, Jesse C, et al. Pathomechanisms of ALS8: altered autophagy and defective RNA binding protein (RBP) homeostasis due to the VAPB P56S mutation. Cell Death Dis. 2021;12:466 pubmed publisher
  • western blot; human; fig 3e
Fauster A, Rebsamen M, Willmann K, César Razquin A, Girardi E, Bigenzahn J, et al. Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking. Cell Death Differ. 2019;26:1138-1155 pubmed publisher
  • other; human; loading ...; fig 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  • western blot; mouse; 1:1000; fig 6a
Pereira R, Tadinada S, Zasadny F, Oliveira K, Pires K, Olvera A, et al. OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance. EMBO J. 2017;36:2126-2145 pubmed publisher
  • western blot; mouse; fig s10
Wassermann Dozorets R, Rubinstein M. C/EBPβ LIP augments cell death by inducing osteoglycin. Cell Death Dis. 2017;8:e2733 pubmed publisher
  • western blot; human; loading ...; fig s6a
Shi B, Huang Q, Birkett R, Doyle R, Dorfleutner A, Stehlik C, et al. SNAPIN is critical for lysosomal acidification and autophagosome maturation in macrophages. Autophagy. 2017;13:285-301 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3a
Cai Y, Yang L, Hu G, Chen X, Niu F, Yuan L, et al. Regulation of morphine-induced synaptic alterations: Role of oxidative stress, ER stress, and autophagy. J Cell Biol. 2016;215:245-258 pubmed
  • immunohistochemistry; mouse; fig 2
Yamanaka T, Tosaki A, Miyazaki H, Kurosawa M, Koike M, Uchiyama Y, et al. Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS. Sci Rep. 2016;6:34575 pubmed publisher
  • western blot; human; fig 1a
Chaveroux C, Sarcinelli C, Barbet V, Belfeki S, Barthelaix A, Ferraro Peyret C, et al. Nutrient shortage triggers the hexosamine biosynthetic pathway via the GCN2-ATF4 signalling pathway. Sci Rep. 2016;6:27278 pubmed publisher
  • western blot; rat; 1:1000; fig 6
Nosak C, Silva P, Sollazzo P, Moon K, Odisho T, Foster L, et al. Jagn1 Is Induced in Response to ER Stress and Regulates Proinsulin Biosynthesis. PLoS ONE. 2016;11:e0149177 pubmed publisher
  • western blot; human; fig 3
Cherepanova N, Gilmore R. Mammalian cells lacking either the cotranslational or posttranslocational oligosaccharyltransferase complex display substrate-dependent defects in asparagine linked glycosylation. Sci Rep. 2016;6:20946 pubmed publisher
  • western blot; human
Cavieres V, González A, Muñoz V, Yefi C, Bustamante H, Barraza R, et al. Tetrahydrohyperforin Inhibits the Proteolytic Processing of Amyloid Precursor Protein and Enhances Its Degradation by Atg5-Dependent Autophagy. PLoS ONE. 2015;10:e0136313 pubmed publisher
  • western blot; rat; 1:1000; fig 3
Wu P, Yen J, Kou M, Wu M. Luteolin and Apigenin Attenuate 4-Hydroxy-2-Nonenal-Mediated Cell Death through Modulation of UPR, Nrf2-ARE and MAPK Pathways in PC12 Cells. PLoS ONE. 2015;10:e0130599 pubmed publisher
  • western blot; mouse; 1:2000
Hou Y, Ernst S, Stuenkel E, Lentz S, Williams J. Rab27A Is Present in Mouse Pancreatic Acinar Cells and Is Required for Digestive Enzyme Secretion. PLoS ONE. 2015;10:e0125596 pubmed publisher
  • western blot; human; 1:2000; fig s2b
  • western blot; mouse; fig 3g
Das I, Krzyzosiak A, Schneider K, Wrabetz L, D Antonio M, Barry N, et al. Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit. Science. 2015;348:239-42 pubmed publisher
  • western blot; human; 1:1000; fig 2
Yang S, Yang X, Cao G. Acetyl-l-carnitine prevents homocysteine-induced suppression of Nrf2/Keap1 mediated antioxidation in human lens epithelial cells. Mol Med Rep. 2015;12:1145-50 pubmed publisher
  • western blot; rat
Matsuo R, Morihara H, Mohri T, Murasawa S, Takewaki K, Nakayama H, et al. The inhibition of N-glycosylation of glycoprotein 130 molecule abolishes STAT3 activation by IL-6 family cytokines in cultured cardiac myocytes. PLoS ONE. 2014;9:e111097 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
Zhang Y, Jansen West K, Xu Y, Gendron T, Bieniek K, Lin W, et al. Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress. Acta Neuropathol. 2014;128:505-24 pubmed publisher
  • western blot; human; fig 1,2,3,4,5,6
Cherepanova N, Shrimal S, Gilmore R. Oxidoreductase activity is necessary for N-glycosylation of cysteine-proximal acceptor sites in glycoproteins. J Cell Biol. 2014;206:525-39 pubmed publisher
  • western blot; African green monkey
Nuss J, Kehn Hall K, Benedict A, Costantino J, Ward M, Peyser B, et al. Multi-faceted proteomic characterization of host protein complement of Rift Valley fever virus virions and identification of specific heat shock proteins, including HSP90, as important viral host factors. PLoS ONE. 2014;9:e93483 pubmed publisher
  • flow cytometry; human
  • western blot; human
Chang C, Chen C, Wu M, Chen Y, Chen C, Sheu S, et al. Active Component of Antrodia cinnamomea Mycelia Targeting Head and Neck Cancer Initiating Cells through Exaggerated Autophagic Cell Death. Evid Based Complement Alternat Med. 2013;2013:946451 pubmed publisher
  • western blot; pigs
Banduseela V, Chen Y, Kultima H, Norman H, Aare S, Radell P, et al. Impaired autophagy, chaperone expression, and protein synthesis in response to critical illness interventions in porcine skeletal muscle. Physiol Genomics. 2013;45:477-86 pubmed publisher
  • western blot; human; fig 1
Wei P, Lo W, Su M, Shew J, Lee W. Non-targeting siRNA induces NPGPx expression to cooperate with exoribonuclease XRN2 for releasing the stress. Nucleic Acids Res. 2012;40:323-32 pubmed publisher
  • western blot; human
Tsaytler P, Harding H, Ron D, Bertolotti A. Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. Science. 2011;332:91-4 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
  • western blot; mouse; fig 2e
Watson G, Andley U. Activation of the unfolded protein response by a cataract-associated ?A-crystallin mutation. Biochem Biophys Res Commun. 2010;401:192-6 pubmed publisher
  • immunocytochemistry; human
Hu Q, Loeys B, Coucke P, De Paepe A, Mecham R, Choi J, et al. Fibulin-5 mutations: mechanisms of impaired elastic fiber formation in recessive cutis laxa. Hum Mol Genet. 2006;15:3379-86 pubmed
Yi J, Kim T, Pak J, Chung J. Protective Effects of Glucose-Related Protein 78 and 94 on Cisplatin-Mediated Ototoxicity. Antioxidants (Basel). 2020;9: pubmed publisher
Eyking A, Ferber F, Köhler S, Reis H, Cario E. TRIM58 Restrains Intestinal Mucosal Inflammation by Negatively Regulating TLR2 in Myeloid Cells. J Immunol. 2019;203:1636-1649 pubmed publisher
Sadleir K, Popovic J, Vassar R. ER stress is not elevated in the 5XFAD mouse model of Alzheimer's disease. J Biol Chem. 2018;293:18434-18443 pubmed publisher
Bakewell S, Rangel D, Ha D, Sethuraman J, Crouse R, Hadley E, et al. Suppression of stress induction of the 78-kilodalton glucose regulated protein (GRP78) in cancer by IT-139, an anti-tumor ruthenium small molecule inhibitor. Oncotarget. 2018;9:29698-29714 pubmed publisher
Stern A, Ghura S, Gannon P, Akay Espinoza C, Phan J, Yee A, et al. BACE1 Mediates HIV-Associated and Excitotoxic Neuronal Damage Through an APP-Dependent Mechanism. J Neurosci. 2018;38:4288-4300 pubmed publisher
Zhao Y, Liu N, Miao G, Chen Y, Zhao H, Zhang H. The ER Contact Proteins VAPA/B Interact with Multiple Autophagy Proteins to Modulate Autophagosome Biogenesis. Curr Biol. 2018;28:1234-1245.e4 pubmed publisher
Jheng J, Chen Y, Ao U, Chan D, Huang J, Hung K, et al. The double-edged sword of endoplasmic reticulum stress in uremic sarcopenia through myogenesis perturbation. J Cachexia Sarcopenia Muscle. 2018;9:570-584 pubmed publisher
Zhao Y, Chen Y, Miao G, Zhao H, Qu W, Li D, et al. The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation. Mol Cell. 2017;67:974-989.e6 pubmed publisher
Chen D, Xiang Q, Nicholas J. Human Herpesvirus 8 Interleukin-6 Interacts with Calnexin Cycle Components and Promotes Protein Folding. J Virol. 2017;91: pubmed publisher
Shrimal S, Cherepanova N, Gilmore R. DC2 and KCP2 mediate the interaction between the oligosaccharyltransferase and the ER translocon. J Cell Biol. 2017;216:3625-3638 pubmed publisher
Shen J, Ha D, Zhu G, Rangel D, Kobielak A, Gill P, et al. GRP78 haploinsufficiency suppresses acinar-to-ductal metaplasia, signaling, and mutant Kras-driven pancreatic tumorigenesis in mice. Proc Natl Acad Sci U S A. 2017;114:E4020-E4029 pubmed publisher
Panda P, Behera B, Meher B, Das D, Mukhopadhyay S, Sinha N, et al. Abrus Agglutinin, a type II ribosome inactivating protein inhibits Akt/PH domain to induce endoplasmic reticulum stress mediated autophagy-dependent cell death. Mol Carcinog. 2017;56:389-401 pubmed publisher
Kondo Y, Masutomi H, Noda Y, Ozawa Y, Takahashi K, Handa S, et al. Senescence marker protein-30/superoxide dismutase 1 double knockout mice exhibit increased oxidative stress and hepatic steatosis. FEBS Open Bio. 2014;4:522-32 pubmed publisher
Dezwaan McCabe D, Riordan J, Arensdorf A, Icardi M, Dupuy A, Rutkowski D. The stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesis. PLoS Genet. 2013;9:e1003937 pubmed publisher
Ishii T, Seike T, Nakashima T, Jüliger S, Maharaj L, Soga S, et al. Anti-tumor activity against multiple myeloma by combination of KW-2478, an Hsp90 inhibitor, with bortezomib. Blood Cancer J. 2012;2:e68 pubmed publisher
product information
Cat.# :
610978
Brand :
BD Transduction Laboratories
Name :
BiP
Format :
Purified
Clone :
40/BiP
Isotype :
Ms IgG 2a
React :
Hu , Ms , Rat , Dog
Conc :
250 µg/ml
Apps :
WB
Size :
50 µg
Status :
RUO
more info or order :
company information