product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Cdc42
catalog :
610929
quantity :
150 µg
price :
415.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
44/CDC42
reactivity :
human, mouse, rat, dogs, zebrafish
application :
western blot, immunocytochemistry, western blot knockout validation
more info or order :
citations: 18
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; loading ...; fig 3a
Ge J, Burnier L, Adamopoulou M, Kwa M, Schaks M, Rottner K, et al. RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells. J Biol Chem. 2018;293:9358-9369 pubmed publisher
  • western blot; mouse; fig 8
Han F, Liu C, Zhang L, Zhou Y, Qin Y, Wang Y, et al. Globozoospermia and lack of acrosome formation in GM130-deficient mice. Cell Death Dis. 2017;8:e2532 pubmed publisher
  • western blot; human; fig 1s1
Mounir Z, Korn J, Westerling T, Lin F, Kirby C, Schirle M, et al. ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor. elife. 2016;5: pubmed publisher
  • western blot; human; fig s5
Hwang D, Kohl S, Fan X, Vivante A, Chan S, Dworschak G, et al. Mutations of the SLIT2-ROBO2 pathway genes SLIT2 and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract. Hum Genet. 2015;134:905-16 pubmed publisher
  • western blot; zebrafish ; fig 1d
Choi S, Baek J, Zuo X, Kim S, Dunaief J, Lipschutz J. Cdc42 and sec10 Are Required for Normal Retinal Development in Zebrafish. Invest Ophthalmol Vis Sci. 2015;56:3361-70 pubmed publisher
  • immunocytochemistry; human; fig s4g
Artym V, Swatkoski S, Matsumoto K, Campbell C, Petrie R, Dimitriadis E, et al. Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network. J Cell Biol. 2015;208:331-50 pubmed publisher
  • western blot; mouse; 1:1000
Bray K, Gillette M, Young J, Loughran E, Hwang M, Sears J, et al. Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migration. Breast Cancer Res. 2013;15:R91 pubmed
  • western blot; human
Fisher K, Pop A, Koh W, Anthis N, Saunders W, Davis G. Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling. Mol Cancer. 2006;5:69 pubmed
Singh V, Davidson A, Hume P, Koronakis V. Pathogenic Escherichia coli Hijacks GTPase-Activated p21-Activated Kinase for Actin Pedestal Formation. MBio. 2019;10: pubmed publisher
Mukhamedova N, Hoang A, Dragoljevic D, Dubrovsky L, Pushkarsky T, Low H, et al. Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells. PLoS Pathog. 2019;15:e1007907 pubmed publisher
Durré T, Morfoisse F, Erpicum C, Ebroin M, Blacher S, García Caballero M, et al. uPARAP/Endo180 receptor is a gatekeeper of VEGFR-2/VEGFR-3 heterodimerisation during pathological lymphangiogenesis. Nat Commun. 2018;9:5178 pubmed publisher
Luo W, Song Z, Sun H, Liang J, Zhao S. Bergamottin, a natural furanocoumarin abundantly present in grapefruit juice, suppresses the invasiveness of human glioma cells via inactivation of Rac1 signaling. Oncol Lett. 2018;15:3259-3266 pubmed publisher
Chang W, Liu Y, Dang Y, Jiang X, Xu H, Huang X, et al. PLAC8, a new marker for human interstitial extravillous trophoblast cells, promotes their invasion and migration. Development. 2018;145: pubmed publisher
Cho H, Hwang Y, Yoon J, Lee M, Lee H, Daar I. EphrinB1 promotes cancer cell migration and invasion through the interaction with RhoGDI1. Oncogene. 2018;37:861-872 pubmed publisher
Tsuboi M, Taniuchi K, Shimizu T, Saito M, Saibara T. The transcription factor HOXB7 regulates ERK kinase activity and thereby stimulates the motility and invasiveness of pancreatic cancer cells. J Biol Chem. 2017;292:17681-17702 pubmed publisher
Chiang T, Wu H, Lee F. ADP-ribosylation factor-like 4C binding to filamin-A modulates filopodium formation and cell migration. Mol Biol Cell. 2017;28:3013-3028 pubmed publisher
Zimmerman S, Asokan S, Kuhlman B, Bear J. Cells lay their own tracks - optogenetic Cdc42 activation stimulates fibronectin deposition supporting directed migration. J Cell Sci. 2017;130:2971-2983 pubmed publisher
Misselwitz B, Dilling S, Vonaesch P, Sacher R, Snijder B, Schlumberger M, et al. RNAi screen of Salmonella invasion shows role of COPI in membrane targeting of cholesterol and Cdc42. Mol Syst Biol. 2011;7:474 pubmed publisher
product information
Cat.# :
610929
Brand :
BD Transduction Laboratories
Name :
Cdc42
Format :
Purified
Clone :
44/CDC42
Isotype :
Ms IgG 1
React :
Hu , Ms , Rat , Dog
Conc :
250 µg/ml
Apps :
WB
Size :
150 µg
Status :
RUO
List Price :
415.00 USD
more info or order :
company information