Published Application/Species/Sample/Dilution | Reference |
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- western blot; human; 1:2000; loading ...; fig 4b
| Prins M, Giugliano F, van Roest M, van de Graaf S, Koelink P, Wildenberg M. Thiopurines correct the effects of autophagy impairment on intestinal healing - a potential role for ARHGAP18/RhoA. Dis Model Mech. 2021;14: pubmed publisher
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- western blot; human; 1:1000; loading ...; fig 4a
| Cendrowski J, Kaczmarek M, Mazur M, Kuzmicz Kowalska K, Jastrzębski K, Brewińska Olchowik M, et al. Splicing variation of BMP2K balances abundance of COPII assemblies and autophagic degradation in erythroid cells. elife. 2020;9: pubmed publisher
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- western blot; human; loading ...; fig 3c
| Chen W, Wang Q, Xu X, Saxton B, Tessema M, Leng S, et al. Vasorin/ATIA Promotes Cigarette Smoke-Induced Transformation of Human Bronchial Epithelial Cells by Suppressing Autophagy-Mediated Apoptosis. Transl Oncol. 2020;13:32-41 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 1d, 1f
- western blot; human; 1:1000; loading ...; fig 8b
| Yang Y, Willis T, Button R, Strang C, Fu Y, Wen X, et al. Cytoplasmic DAXX drives SQSTM1/p62 phase condensation to activate Nrf2-mediated stress response. Nat Commun. 2019;10:3759 pubmed publisher
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- immunocytochemistry; human; 1:500; loading ...; fig 6e
- western blot; human; 1:2500; loading ...; fig 1e
| Goodwin J, Dowdle W, Dejesus R, Wang Z, Bergman P, Kobylarz M, et al. Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9. Cell Rep. 2017;20:2341-2356 pubmed publisher
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- immunocytochemistry; human; 1:2000; fig 7
- western blot; human; 1:2000; fig 3b
| Wang G, Zhou H, Strulovici Barel Y, Al Hijji M, Ou X, Salit J, et al. Role of OSGIN1 in mediating smoking-induced autophagy in the human airway epithelium. Autophagy. 2017;13:1205-1220 pubmed publisher
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- western blot; human; loading ...; fig e1c
- western blot; mouse; loading ...; fig e2d
| Ashkenazi A, Bento C, Ricketts T, Vicinanza M, Siddiqi F, Pavel M, et al. Polyglutamine tracts regulate beclin 1-dependent autophagy. Nature. 2017;545:108-111 pubmed publisher
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- reverse phase protein lysate microarray; human; loading ...; fig st6
| Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
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- reverse phase protein lysate microarray; human; loading ...; fig 3a
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- western blot; human; loading ...; fig 2a
| Zhang L, Dai F, Cui L, Zhou B, Guo Y. Up-regulation of the active form of small GTPase Rab13 promotes macroautophagy in vascular endothelial cells. Biochim Biophys Acta Mol Cell Res. 2017;1864:613-624 pubmed publisher
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- western blot; human; loading ...; fig 3a
| Van Puyenbroeck V, Claeys E, Schols D, Bell T, Vermeire K. A Proteomic Survey Indicates Sortilin as a Secondary Substrate of the ER Translocation Inhibitor Cyclotriazadisulfonamide (CADA). Mol Cell Proteomics. 2017;16:157-167 pubmed publisher
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- western blot; human; 1:500; loading ...; fig 3d
| Fernández B, Fdez E, Gomez Suaga P, Gil F, Molina Villalba I, Ferrer I, et al. Iron overload causes endolysosomal deficits modulated by NAADP-regulated 2-pore channels and RAB7A. Autophagy. 2016;12:1487-506 pubmed publisher
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| Dejesus R, Moretti F, McAllister G, Wang Z, Bergman P, Liu S, et al. Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62. elife. 2016;5: pubmed publisher
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- western blot; human; fig s1
| Karvela M, Baquero P, Kuntz E, Mukhopadhyay A, Mitchell R, Allan E, et al. ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells. Autophagy. 2016;12:936-48 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:100; loading ...; tbl 1
| Ito M, Nakamura K, Mori F, Miki Y, Tanji K, Wakabayashi K. Novel eosinophilic neuronal cytoplasmic inclusions in the external cuneate nucleus of humans. Neuropathology. 2016;36:441-447 pubmed publisher
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- immunocytochemistry; human; 1:1000; fig 2
- western blot; human; 1:1000; fig 2
| Button R, Vincent J, Strang C, Luo S. Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis. Oncotarget. 2016;7:5157-75 pubmed publisher
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- immunocytochemistry; human; fig 4
| Puvirajesinghe T, Bertucci F, Jain A, Scerbo P, Belotti E, Audebert S, et al. Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer. Nat Commun. 2016;7:10318 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 1a
- western blot; human; loading ...; fig 3d
| Ivankovic D, Chau K, Schapira A, Gegg M. Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy. J Neurochem. 2016;136:388-402 pubmed publisher
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- immunohistochemistry; rat; fig 6
- western blot; rat; fig 5
| Chen D, Tao X, Wang Y, Tian F, Wei Y, Chen G, et al. Curcumin accelerates reendothelialization and ameliorates intimal hyperplasia in balloon-injured rat carotid artery via the upregulation of endothelial cell autophagy. Int J Mol Med. 2015;36:1563-71 pubmed publisher
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- western blot; human; 1:1000; fig 2
| Bae E, Yang N, Lee C, Kim S, Lee H, Lee S. Haploinsufficiency of cathepsin D leads to lysosomal dysfunction and promotes cell-to-cell transmission of α-synuclein aggregates. Cell Death Dis. 2015;6:e1901 pubmed publisher
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- western blot; human; fig 2e
| Levin A, Koelink P, Bloemendaal F, Vos A, D Haens G, van den Brink G, et al. Autophagy Contributes to the Induction of Anti-TNF Induced Macrophages. J Crohns Colitis. 2016;10:323-9 pubmed publisher
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- western blot; human; 1:1000; fig 4
| Cañeque T, Gomes F, Mai T, Maestri G, Malacria M, Rodriguez R. Synthesis of marmycin A and investigation into its cellular activity. Nat Chem. 2015;7:744-51 pubmed publisher
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- western blot; human; loading ...; fig 2c
| Colecchia D, Rossi M, Sasdelli F, Sanzone S, Strambi A, Chiariello M. MAPK15 mediates BCR-ABL1-induced autophagy and regulates oncogene-dependent cell proliferation and tumor formation. Autophagy. 2015;11:1790-802 pubmed publisher
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- western blot; human; fig 4
| Zhang L, Dai F, Sheng P, Chen Z, Xu Q, Guo Y. Resveratrol analogue 3,4,4'-trihydroxy-trans-stilbene induces apoptosis and autophagy in human non-small-cell lung cancer cells in vitro. Acta Pharmacol Sin. 2015;36:1256-65 pubmed publisher
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- immunocytochemistry; human; 1:200
| Schraivogel D, Schindler S, Danner J, Kremmer E, Pfaff J, Hannus S, et al. Importin-β facilitates nuclear import of human GW proteins and balances cytoplasmic gene silencing protein levels. Nucleic Acids Res. 2015;43:7447-61 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 5
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| Zhang L, Dai F, Cui L, Jing H, Fan P, Tan X, et al. Novel role for TRPC4 in regulation of macroautophagy by a small molecule in vascular endothelial cells. Biochim Biophys Acta. 2015;1853:377-87 pubmed publisher
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- western blot; mouse; 1:1000
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- western blot; human; 1:5000; fig 4
| Dowdle W, Nyfeler B, Nagel J, Elling R, Liu S, Triantafellow E, et al. Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. Nat Cell Biol. 2014;16:1069-79 pubmed publisher
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- immunocytochemistry; human; 1:100; fig 2
- immunocytochemistry; mouse; 1:100; fig s5
| Zhang Y, Jansen West K, Xu Y, Gendron T, Bieniek K, Lin W, et al. Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress. Acta Neuropathol. 2014;128:505-24 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:100
| Mori F, Watanabe Y, Miki Y, Tanji K, Odagiri S, Eto K, et al. Ubiquitin-negative, eosinophilic neuronal cytoplasmic inclusions associated with stress granules and autophagy: an immunohistochemical investigation of two cases. Neuropathology. 2014;34:140-7 pubmed
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- immunohistochemistry - paraffin section; human; 1:100; fig 4
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- immunocytochemistry; human
- western blot; human
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- western blot; human; fig 1a
| Newman A, Scholefield C, Kemp A, Newman M, McIver E, Kamal A, et al. TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-κB signalling. PLoS ONE. 2012;7:e50672 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:100
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| Gleixner A, Verdone B, Otte C, Anderson E, Ramesh N, Shapiro O, et al. NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility. Nat Commun. 2022;13:3380 pubmed publisher
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| Jia R, Bonifacino J. Negative regulation of autophagy by UBA6-BIRC6-mediated ubiquitination of LC3. elife. 2019;8: pubmed publisher
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| Granato M, Gilardini Montani M, Zompetta C, Santarelli R, Gonnella R, Romeo M, et al. Quercetin Interrupts the Positive Feedback Loop Between STAT3 and IL-6, Promotes Autophagy, and Reduces ROS, Preventing EBV-Driven B Cell Immortalization. Biomolecules. 2019;9: pubmed publisher
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| Nair S, Strohecker A, Persaud A, Bissa B, Muruganandan S, McElroy C, et al. Adult stem cell deficits drive Slc29a3 disorders in mice. Nat Commun. 2019;10:2943 pubmed publisher
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| Chiramel A, Meyerson N, McNally K, Broeckel R, Montoya V, Méndez Solís O, et al. TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation. Cell Rep. 2019;27:3269-3283.e6 pubmed publisher
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| Tian Y, Wang J, Huang W, Zeng S, Jiao B, Liu Z, et al. Expansion of Human-Specific GGC Repeat in Neuronal Intranuclear Inclusion Disease-Related Disorders. Am J Hum Genet. 2019;: pubmed publisher
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| Mamelona J, Filice L, Oussedik Y, Crapoulet N, Ouellette R, Marrero A. A novel missense mutation in the MYH7 gene causes an uncharacteristic phenotype of myosin storage myopathy: a case report. BMC Med Genet. 2019;20:78 pubmed publisher
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| Valverde D, Yu S, Boggavarapu V, Kumar N, Lees J, Walz T, et al. ATG2 transports lipids to promote autophagosome biogenesis. J Cell Biol. 2019;218:1787-1798 pubmed publisher
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| Wang Y, Xiong H, Liu D, Hill C, Ertay A, Li J, et al. Autophagy inhibition specifically promotes epithelial-mesenchymal transition and invasion in RAS-mutated cancer cells. Autophagy. 2019;15:886-899 pubmed publisher
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| Birgisdottir A, Mouilleron S, Bhujabal Z, Wirth M, Sjøttem E, Evjen G, et al. Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy. 2019;15:1333-1355 pubmed publisher
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| Larson C, Sandoz K, Cockrell D, Heinzen R. Noncanonical Inhibition of mTORC1 by Coxiella burnetii Promotes Replication within a Phagolysosome-Like Vacuole. MBio. 2019;10: pubmed publisher
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| Hoffmann S, Orlando M, Andrzejak E, Bruns C, Trimbuch T, Rosenmund C, et al. Light-Activated ROS Production Induces Synaptic Autophagy. J Neurosci. 2019;39:2163-2183 pubmed publisher
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| Leonardi M, Perna E, Tronnolone S, Colecchia D, Chiariello M. Activated kinase screening identifies the IKBKE oncogene as a positive regulator of autophagy. Autophagy. 2018;:1-15 pubmed publisher
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| Pellegrini P, Serviss J, Lundbäck T, Bancaro N, Mazurkiewicz M, Kolosenko I, et al. A drug screening assay on cancer cells chronically adapted to acidosis. Cancer Cell Int. 2018;18:147 pubmed publisher
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| Mamais A, Manzoni C, Nazish I, Arber C, Sonustun B, Wray S, et al. Analysis of macroautophagy related proteins in G2019S LRRK2 Parkinson's disease brains with Lewy body pathology. Brain Res. 2018;1701:75-84 pubmed publisher
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| Meyer N, Zielke S, Michaelis J, Linder B, Warnsmann V, Rakel S, et al. AT 101 induces early mitochondrial dysfunction and HMOX1 (heme oxygenase 1) to trigger mitophagic cell death in glioma cells. Autophagy. 2018;14:1693-1709 pubmed publisher
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| Marcassa E, Kallinos A, Jardine J, Rusilowicz Jones E, Martinez A, Kuehl S, et al. Dual role of USP30 in controlling basal pexophagy and mitophagy. EMBO Rep. 2018;19: pubmed publisher
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