product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Flotillin-1
catalog :
610820
quantity :
50 µg
price :
207.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
18/Flotillin-1
reactivity :
African green monkey, human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
citations: 37
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:500; loading ...; fig 4a
van de Vlekkert D, Demmers J, Nguyen X, Campos Y, Machado E, Annunziata I, et al. Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis. Sci Adv. 2019;5:eaav3270 pubmed publisher
  • western blot; human; loading ...; fig 1b
Jeppesen D, Fenix A, Franklin J, Higginbotham J, Zhang Q, Zimmerman L, et al. Reassessment of Exosome Composition. Cell. 2019;177:428-445.e18 pubmed publisher
  • western blot; mouse; loading ...; fig 4g
Guo H, Chitiprolu M, Roncevic L, Javalet C, Hemming F, Trung M, et al. Atg5 Disassociates the V1V0-ATPase to Promote Exosome Production and Tumor Metastasis Independent of Canonical Macroautophagy. Dev Cell. 2017;43:716-730.e7 pubmed publisher
  • western blot; human; 1:1000; fig 2c
Beltrami C, Besnier M, Shantikumar S, Shearn A, Rajakaruna C, Laftah A, et al. Human Pericardial Fluid Contains Exosomes Enriched with Cardiovascular-Expressed MicroRNAs and Promotes Therapeutic Angiogenesis. Mol Ther. 2017;25:679-693 pubmed publisher
  • western blot; mouse; fig 6c
Lu J, Chiang Y, Lin Y, Chang Y, Lu C, Chen T, et al. Disruption of Lipid Raft Function Increases Expression and Secretion of Monocyte Chemoattractant Protein-1 in 3T3-L1 Adipocytes. PLoS ONE. 2016;11:e0169005 pubmed publisher
  • western blot; human; loading ...; fig 1g
Sinha S, Hoshino D, Hong N, Kirkbride K, Grega Larson N, Seiki M, et al. Cortactin promotes exosome secretion by controlling branched actin dynamics. J Cell Biol. 2016;214:197-213 pubmed publisher
  • western blot; human; 1:500; fig 2
Wäster P, Eriksson I, Vainikka L, Rosdahl I, Ollinger K. Extracellular vesicles are transferred from melanocytes to keratinocytes after UVA irradiation. Sci Rep. 2016;6:27890 pubmed publisher
  • western blot; rat; 1:1000; fig s2
Reinhard J, Kriz A, Galic M, Angliker N, Rajalu M, Vogt K, et al. The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory. Nat Commun. 2016;7:11613 pubmed publisher
  • western blot; human; fig s1
Kowal J, Arras G, Colombo M, Jouve M, Morath J, Primdal Bengtson B, et al. Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes. Proc Natl Acad Sci U S A. 2016;113:E968-77 pubmed publisher
  • western blot; mouse; loading ...; fig 2a
Zhu J, Wang Z, Zhang N, Ma J, Xu S, Wang Y, et al. Protein Interacting C-Kinase 1 Modulates Surface Expression of P2Y6 Purinoreceptor, Actin Polymerization and Phagocytosis in Microglia. Neurochem Res. 2016;41:795-803 pubmed publisher
  • western blot; rat
Vanderwerf S, Buck D, Wilmarth P, Sears L, David L, Morton D, et al. Role for Rab10 in Methamphetamine-Induced Behavior. PLoS ONE. 2015;10:e0136167 pubmed publisher
  • western blot; human; fig 1
Dubois F, Leroy C, Simon V, Benistant C, Roche S. YES oncogenic activity is specified by its SH4 domain and regulates RAS/MAPK signaling in colon carcinoma cells. Am J Cancer Res. 2015;5:1972-87 pubmed
  • western blot; African green monkey; 1:1000; loading ...; fig 2b
Nava C, Rupp J, Boissel J, Mignot C, Rastetter A, Amiet C, et al. Hypomorphic variants of cationic amino acid transporter 3 in males with autism spectrum disorders. Amino Acids. 2015;47:2647-58 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4b
Sung B, Ketova T, Hoshino D, Zijlstra A, Weaver A. Directional cell movement through tissues is controlled by exosome secretion. Nat Commun. 2015;6:7164 pubmed publisher
  • western blot; human
Pasqualon T, Pruessmeyer J, Weidenfeld S, Babendreyer A, Groth E, Schumacher J, et al. A transmembrane C-terminal fragment of syndecan-1 is generated by the metalloproteinase ADAM17 and promotes lung epithelial tumor cell migration and lung metastasis formation. Cell Mol Life Sci. 2015;72:3783-801 pubmed publisher
  • immunoprecipitation; human
  • immunocytochemistry; human
  • western blot; human
Jang D, Kwon H, Jeong K, Lee J, Pak Y. Essential role of flotillin-1 palmitoylation in the intracellular localization and signaling function of IGF-1 receptor. J Cell Sci. 2015;128:2179-90 pubmed publisher
  • western blot; human; 1 ug/ml
Lim H, Multhaupt H, Couchman J. Cell surface heparan sulfate proteoglycans control adhesion and invasion of breast carcinoma cells. Mol Cancer. 2015;14:15 pubmed publisher
  • western blot; mouse
Chivet M, Javalet C, Laulagnier K, Blot B, Hemming F, Sadoul R. Exosomes secreted by cortical neurons upon glutamatergic synapse activation specifically interact with neurons. J Extracell Vesicles. 2014;3:24722 pubmed publisher
  • western blot; human
Orchard Webb D, Lee T, Cook G, Blair G. CUB domain containing protein 1 (CDCP1) modulates adhesion and motility in colon cancer cells. BMC Cancer. 2014;14:754 pubmed publisher
  • western blot; mouse; 1:500; fig 2g
Pannasch U, Freche D, Dallérac G, Ghezali G, Escartin C, Ezan P, et al. Connexin 30 sets synaptic strength by controlling astroglial synapse invasion. Nat Neurosci. 2014;17:549-58 pubmed publisher
  • western blot; human
Arkhipova K, Sheyderman A, Laktionov K, Mochalnikova V, Zborovskaya I. Simultaneous expression of flotillin-1, flotillin-2, stomatin and caveolin-1 in non-small cell lung cancer and soft tissue sarcomas. BMC Cancer. 2014;14:100 pubmed publisher
  • immunoprecipitation; human; 1:1000
  • western blot; human; 1:1000
Aulakh G, Balachandran Y, Liu L, Singh B. Angiostatin inhibits activation and migration of neutrophils. Cell Tissue Res. 2014;355:375-96 pubmed publisher
Sackmann V, Sinha M, Sackmann C, Civitelli L, Bergström J, Ansell Schultz A, et al. Inhibition of nSMase2 Reduces the Transfer of Oligomeric α-Synuclein Irrespective of Hypoxia. Front Mol Neurosci. 2019;12:200 pubmed publisher
Riento K, Zhang Q, Clark J, Begum F, Stephens E, Wakelam M, et al. Flotillin proteins recruit sphingosine to membranes and maintain cellular sphingosine-1-phosphate levels. PLoS ONE. 2018;13:e0197401 pubmed publisher
Hu J, Dziumbla S, Lin J, Bibli S, Zukunft S, de Mos J, et al. Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy. Nature. 2017;552:248-252 pubmed publisher
Yoon S, Kovalenko A, Bogdanov K, Wallach D. MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation. Immunity. 2017;47:51-65.e7 pubmed publisher
Luo L, Bokil N, Wall A, Kapetanovic R, Lansdaal N, Marceline F, et al. SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages. Nat Commun. 2017;8:14133 pubmed publisher
Brandstaetter H, Kishi Itakura C, Tumbarello D, Manstein D, Buss F. Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion. Autophagy. 2014;10:2310-23 pubmed publisher
Jerman S, Ward H, Lee R, Lopes C, Fry A, Macdougall M, et al. OFD1 and flotillins are integral components of a ciliary signaling protein complex organized by polycystins in renal epithelia and odontoblasts. PLoS ONE. 2014;9:e106330 pubmed publisher
Govender Y, Avenant C, Verhoog N, Ray R, Grantham N, Africander D, et al. The injectable-only contraceptive medroxyprogesterone acetate, unlike norethisterone acetate and progesterone, regulates inflammatory genes in endocervical cells via the glucocorticoid receptor. PLoS ONE. 2014;9:e96497 pubmed publisher
Yamada T, Shigemura H, Ishiguro N, Inoshima Y. Cell Infectivity in relation to bovine leukemia virus gp51 and p24 in bovine milk exosomes. PLoS ONE. 2013;8:e77359 pubmed publisher
Gagné V, Marois L, Levesque J, Galarneau H, Lahoud M, Caminschi I, et al. Modulation of monosodium urate crystal-induced responses in neutrophils by the myeloid inhibitory C-type lectin-like receptor: potential therapeutic implications. Arthritis Res Ther. 2013;15:R73 pubmed publisher
Fowler S, Akins M, Zhou H, Figeys D, Bennett S. The liver connexin32 interactome is a novel plasma membrane-mitochondrial signaling nexus. J Proteome Res. 2013;12:2597-610 pubmed publisher
Zhu H, Guariglia S, Yu R, Li W, Brancho D, Peinado H, et al. Mutation of SIMPLE in Charcot-Marie-Tooth 1C alters production of exosomes. Mol Biol Cell. 2013;24:1619-37, S1-3 pubmed publisher
Kiss K, Brozik A, Kucsma N, Toth A, Gera M, Berry L, et al. Shifting the paradigm: the putative mitochondrial protein ABCB6 resides in the lysosomes of cells and in the plasma membrane of erythrocytes. PLoS ONE. 2012;7:e37378 pubmed publisher
Yamamori S, Itakura M, Sugaya D, Katsumata O, Sakagami H, Takahashi M. Differential expression of SNAP-25 family proteins in the mouse brain. J Comp Neurol. 2011;519:916-32 pubmed publisher
Kwon H, Jeong K, Hwang E, Park J, Pak Y. A novel domain of caveolin-2 that controls nuclear targeting: regulation of insulin-specific ERK activation and nuclear translocation by caveolin-2. J Cell Mol Med. 2011;15:888-908 pubmed publisher
product information
Cat.# :
610820
Brand :
BD Transduction Laboratories
Name :
Flotillin-1
Format :
Purified
Clone :
18/Flotillin-1
Isotype :
Ms IgG 1
React :
Hu , Ms , Rat , Chick
Conc :
250 µg/ml
Apps :
IF , WB
Size :
50 µg
Status :
RUO
List Price :
207.00 USD
more info or order :
company information