product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
PTP1D
catalog :
610621
quantity :
50 µg
price :
207.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
79/PTP1D/SHP2
reactivity :
human, mouse, rat, dog, chicken
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 5c
Juhasz A, Markel S, Gaur S, Liu H, Lu J, Jiang G, et al. NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction. J Biol Chem. 2017;292:7866-7887 pubmed publisher
  • western blot; human
Pavlova N, Pallasch C, Elia A, Braun C, Westbrook T, Hemann M, et al. A role for PVRL4-driven cell-cell interactions in tumorigenesis. elife. 2013;2:e00358 pubmed publisher
Ran H, Kong S, Zhang S, Cheng J, Zhou C, He B, et al. Nuclear Shp2 directs normal embryo implantation via facilitating the ERα tyrosine phosphorylation by the Src kinase. Proc Natl Acad Sci U S A. 2017;114:4816-4821 pubmed publisher
Zhang L, Zhang W, Li Y, Alvarez A, Li Z, Wang Y, et al. SHP-2-upregulated ZEB1 is important for PDGFRα-driven glioma epithelial-mesenchymal transition and invasion in mice and humans. Oncogene. 2016;35:5641-5652 pubmed publisher
Varughese E, Kasper S, Anneken E, Yadav J. SHP-2 Mediates Cryptosporidium parvum Infectivity in Human Intestinal Epithelial Cells. PLoS ONE. 2015;10:e0142219 pubmed publisher
Davies K, Mahale S, Astling D, Aisner D, Le A, Hinz T, et al. Resistance to ROS1 inhibition mediated by EGFR pathway activation in non-small cell lung cancer. PLoS ONE. 2013;8:e82236 pubmed publisher
Selimoglu Buet D, Gallais I, Denis N, Guillouf C, Moreau Gachelin F. Oncogenic kit triggers Shp2/Erk1/2 pathway to down-regulate the pro-apoptotic protein Bim and to promote apoptosis resistance in leukemic cells. PLoS ONE. 2012;7:e49052 pubmed publisher
Nabinger S, Li X, Ramdas B, He Y, Zhang X, Zeng L, et al. The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo. Leukemia. 2013;27:398-408 pubmed publisher
product information
Cat.# :
610621
Brand :
BD Transduction Laboratories
Name :
PTP1D
Format :
Purified
Clone :
79/PTP1D/SHP2
Isotype :
Ms IgG 1
React :
Hu , Ms , Rat , Dog , Chick , Frog
Conc :
250 µg/ml
Apps :
IF , IP , WB
Size :
50 µg
Status :
RUO
List Price :
207.00 USD
more info or order :
company information