product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Bcl-2
catalog :
610539
quantity :
150 µg
price :
415.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
7/Bcl-2
reactivity :
human, mouse, rat, dogs, chicken
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:500; loading ...; fig 4b
Xie Y, Ma W, Meng J, Ren X. Knockdown of ZFPL1 results in increased autophagy and autophagy‑related cell death in NCI‑N87 and BGC‑823 human gastric carcinoma cell lines. Mol Med Rep. 2017;15:2633-2642 pubmed publisher
  • western blot; mouse; loading ...; fig 1b
Schenk R, Tuzlak S, Carrington E, Zhan Y, Heinzel S, Teh C, et al. Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment. Cell Death Differ. 2017;24:534-545 pubmed publisher
  • western blot; human; fig 4
De Toni E, Ziesch A, Rizzani A, Török H, Hocke S, Lü S, et al. Inactivation of BRCA2 in human cancer cells identifies a subset of tumors with enhanced sensitivity towards death receptor-mediated apoptosis. Oncotarget. 2016;7:9477-90 pubmed publisher
  • western blot; mouse; 1:100; fig 6d, 6e
Anderson K, Russell A, Foletta V. NDRG2 promotes myoblast proliferation and caspase 3/7 activities during differentiation, and attenuates hydrogen peroxide - But not palmitate-induced toxicity. FEBS Open Bio. 2015;5:668-81 pubmed publisher
  • western blot; human; 1:1000; fig 3
Lorkova L, Scigelova M, Arrey T, Vit O, Pospisilova J, Doktorova E, et al. Detailed Functional and Proteomic Characterization of Fludarabine Resistance in Mantle Cell Lymphoma Cells. PLoS ONE. 2015;10:e0135314 pubmed publisher
  • immunoprecipitation; human
Morita A, Ariyasu S, Wang B, Asanuma T, Onoda T, Sawa A, et al. AS-2, a novel inhibitor of p53-dependent apoptosis, prevents apoptotic mitochondrial dysfunction in a transcription-independent manner and protects mice from a lethal dose of ionizing radiation. Biochem Biophys Res Commun. 2014;450:1498-504 pubmed publisher
  • western blot; human
Cen B, Xiong Y, Song J, Mahajan S, DuPont R, McEachern K, et al. The Pim-1 protein kinase is an important regulator of MET receptor tyrosine kinase levels and signaling. Mol Cell Biol. 2014;34:2517-32 pubmed publisher
  • western blot; human
Hollevoet K, Antignani A, FitzGerald D, Pastan I. Combining the antimesothelin immunotoxin SS1P with the BH3-mimetic ABT-737 induces cell death in SS1P-resistant pancreatic cancer cells. J Immunother. 2014;37:8-15 pubmed publisher
Caeser R, Di Re M, Krupka J, Gao J, Lara Chica M, Dias J, et al. Genetic modification of primary human B cells to model high-grade lymphoma. Nat Commun. 2019;10:4543 pubmed publisher
Lu C, Yang D, Sabbatini M, Colby A, Grinstaff M, Oberlies N, et al. Contrasting roles of H3K4me3 and H3K9me3 in regulation of apoptosis and gemcitabine resistance in human pancreatic cancer cells. BMC Cancer. 2018;18:149 pubmed publisher
Chen C, Chen N, Feng C, Cheng S, Hung H, Tsui K, et al. A Coral-Derived Compound Improves Functional Recovery after Spinal Cord Injury through Its Antiapoptotic and Anti-Inflammatory Effects. Mar Drugs. 2016;14: pubmed publisher
Farrugia M, Sharma S, Lin C, McLaughlin S, Vanderbilt D, Ammer A, et al. Regulation of anti-apoptotic signaling by Kruppel-like factors 4 and 5 mediates lapatinib resistance in breast cancer. Cell Death Dis. 2015;6:e1699 pubmed publisher
Liu F, Hu X, Zimmerman M, Waller J, Wu P, Hayes Jordan A, et al. TNF? cooperates with IFN-? to repress Bcl-xL expression to sensitize metastatic colon carcinoma cells to TRAIL-mediated apoptosis. PLoS ONE. 2011;6:e16241 pubmed publisher
Taylor E, Li J, Tupper J, Rossi A, Winn R, Harlan J. GEA 3162, a peroxynitrite donor, induces Bcl-2-sensitive, p53-independent apoptosis in murine bone marrow cells. Biochem Pharmacol. 2007;74:1039-49 pubmed
Nilsen J, Chen S, Irwin R, Iwamoto S, Brinton R. Estrogen protects neuronal cells from amyloid beta-induced apoptosis via regulation of mitochondrial proteins and function. BMC Neurosci. 2006;7:74 pubmed
product information
Cat.# :
610539
Brand :
BD Transduction Laboratories
Name :
Bcl-2
Format :
Purified
Clone :
7/Bcl-2
Isotype :
Ms IgG 1
React :
Hu , Ms , Rat , Dog , Chick
Conc :
250 µg/ml
Apps :
IF , IHC , IP , WB
Size :
150 µg
Status :
RUO
List Price :
415.00 USD
more info or order :
company information