product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Bcl-2
catalog :
610538
quantity :
50 µg
price :
207.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
7/Bcl-2
reactivity :
human, mouse, rat, dogs, chicken
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 17
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 1b
Schenk R, Tuzlak S, Carrington E, Zhan Y, Heinzel S, Teh C, et al. Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment. Cell Death Differ. 2017;24:534-545 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 6b
Torres A, Vargas Y, Uribe D, Jaramillo C, Gleisner A, Salazar Onfray F, et al. Adenosine A3 receptor elicits chemoresistance mediated by multiple resistance-associated protein-1 in human glioblastoma stem-like cells. Oncotarget. 2016;7:67373-67386 pubmed publisher
  • western blot; human; fig 4a
Ahmed N, Murakami M, Hirose Y, Nakashima M. Therapeutic Potential of Dental Pulp Stem Cell Secretome for Alzheimer's Disease Treatment: An In Vitro Study. Stem Cells Int. 2016;2016:8102478 pubmed publisher
  • western blot; human; 1:500; fig 6
Conway A, Van Nostrand E, Pratt G, Aigner S, Wilbert M, Sundararaman B, et al. Enhanced CLIP Uncovers IMP Protein-RNA Targets in Human Pluripotent Stem Cells Important for Cell Adhesion and Survival. Cell Rep. 2016;15:666-679 pubmed publisher
  • western blot; human; loading ...; fig 5a,5c
Farrugia M, Sharma S, Lin C, McLaughlin S, Vanderbilt D, Ammer A, et al. Regulation of anti-apoptotic signaling by Kruppel-like factors 4 and 5 mediates lapatinib resistance in breast cancer. Cell Death Dis. 2015;6:e1699 pubmed publisher
  • western blot; human; fig 5
Huang P, Hung S, Pao C, Wang T. N-(1-pyrenyl) maleimide induces bak oligomerization and mitochondrial dysfunction in Jurkat Cells. Biomed Res Int. 2015;2015:798489 pubmed publisher
  • immunoprecipitation; human
Morita A, Ariyasu S, Wang B, Asanuma T, Onoda T, Sawa A, et al. AS-2, a novel inhibitor of p53-dependent apoptosis, prevents apoptotic mitochondrial dysfunction in a transcription-independent manner and protects mice from a lethal dose of ionizing radiation. Biochem Biophys Res Commun. 2014;450:1498-504 pubmed publisher
  • western blot; human
Dho S, Deverman B, Lapid C, Manson S, Gan L, Riehm J, et al. Control of cellular Bcl-xL levels by deamidation-regulated degradation. PLoS Biol. 2013;11:e1001588 pubmed publisher
  • western blot; human; 1:500
Thompson R, Vardinogiannis I, Gilmore T. The sensitivity of diffuse large B-cell lymphoma cell lines to histone deacetylase inhibitor-induced apoptosis is modulated by BCL-2 family protein activity. PLoS ONE. 2013;8:e62822 pubmed publisher
Caeser R, Di Re M, Krupka J, Gao J, Lara Chica M, Dias J, et al. Genetic modification of primary human B cells to model high-grade lymphoma. Nat Commun. 2019;10:4543 pubmed publisher
Pomeroy E, Lee L, Lee R, Schirm D, Temiz N, Ma J, et al. Ras oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS(V12) oncogene addiction in acute myeloid leukemia. Oncogene. 2017;36:3263-3273 pubmed publisher
Eckfeldt C, Pomeroy E, Lee R, Hazen K, Lee L, Moriarity B, et al. RALB provides critical survival signals downstream of Ras in acute myeloid leukemia. Oncotarget. 2016;7:65147-65156 pubmed publisher
Prysyazhna O, Burgoyne J, Scotcher J, Grover S, Kass D, Eaton P. Phosphodiesterase 5 Inhibition Limits Doxorubicin-induced Heart Failure by Attenuating Protein Kinase G I? Oxidation. J Biol Chem. 2016;291:17427-36 pubmed publisher
Xue T, Tao L, Zhang J, Zhang P, Liu X, Chen G, et al. Intestinal ischemic preconditioning reduces liver ischemia reperfusion injury in rats. Mol Med Rep. 2016;13:2511-7 pubmed publisher
Liu X, Chen X, Rycaj K, Chao H, Deng Q, Jeter C, et al. Systematic dissection of phenotypic, functional, and tumorigenic heterogeneity of human prostate cancer cells. Oncotarget. 2015;6:23959-86 pubmed
Woodcock J, Coolen C, Goodwin K, Baek D, Bittman R, Samuel M, et al. Destabilisation of dimeric 14-3-3 proteins as a novel approach to anti-cancer therapeutics. Oncotarget. 2015;6:14522-36 pubmed
Stratos I, Li Z, Rotter R, Herlyn P, Mittlmeier T, Vollmar B. Inhibition of caspase mediated apoptosis restores muscle function after crush injury in rat skeletal muscle. Apoptosis. 2012;17:269-77 pubmed publisher
product information
Cat.# :
610538
Brand :
BD Transduction Laboratories
Name :
Bcl-2
Format :
Purified
Clone :
7/Bcl-2
Isotype :
Ms IgG 1
React :
Hu , Ms , Rat , Dog , Chick
Conc :
250 µg/ml
Apps :
IF , IHC , IP , WB
Size :
50 µg
Status :
RUO
List Price :
207.00 USD
more info or order :
company information