product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Clathrin Heavy Chain
catalog :
610500
quantity :
150 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
23/Clathrin Heavy Chain
reactivity :
human, mouse, rat, dogs, chicken, pigs
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, other
more info or order :
citations: 19
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 4a, 4g
Kimura H, Sada R, Takada N, Harada A, Doki Y, Eguchi H, et al. The Dickkopf1 and FOXM1 positive feedback loop promotes tumor growth in pancreatic and esophageal cancers. Oncogene. 2021;40:4486-4502 pubmed publisher
  • western blot; human; loading ...; fig 1c
Van Puyenbroeck V, Claeys E, Schols D, Bell T, Vermeire K. A Proteomic Survey Indicates Sortilin as a Secondary Substrate of the ER Translocation Inhibitor Cyclotriazadisulfonamide (CADA). Mol Cell Proteomics. 2017;16:157-167 pubmed publisher
  • other; human; loading ...; fig 3
Su W, Kowalczyk A. The VE-cadherin cytoplasmic domain undergoes proteolytic processing during endocytosis. Mol Biol Cell. 2017;28:76-84 pubmed publisher
  • western blot; mouse; fig 2c
Muhsin Sharafaldine M, Saunderson S, Dunn A, Faed J, Kleffmann T, McLellan A. Procoagulant and immunogenic properties of melanoma exosomes, microvesicles and apoptotic vesicles. Oncotarget. 2016;7:56279-56294 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 4
  • western blot; human; 1:1000; fig s1
Rao S, Flores Rodriguez N, Page S, Wong C, Robinson P, Chircop M. The Clathrin-dependent Spindle Proteome. Mol Cell Proteomics. 2016;15:2537-53 pubmed publisher
  • western blot; pigs ; 1:1000; loading ...; fig 1c
Hernaez B, Guerra M, Salas M, Andres G. African Swine Fever Virus Undergoes Outer Envelope Disruption, Capsid Disassembly and Inner Envelope Fusion before Core Release from Multivesicular Endosomes. PLoS Pathog. 2016;12:e1005595 pubmed publisher
  • western blot; human; fig 1
Dumas A, Lê Bury G, Marie Anaïs F, Herit F, Mazzolini J, Guilbert T, et al. The HIV-1 protein Vpr impairs phagosome maturation by controlling microtubule-dependent trafficking. J Cell Biol. 2015;211:359-72 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 4,5
Gingras S, Earls L, Howell S, Smeyne R, Zakharenko S, Pelletier S. SCYL2 Protects CA3 Pyramidal Neurons from Excitotoxicity during Functional Maturation of the Mouse Hippocampus. J Neurosci. 2015;35:10510-22 pubmed publisher
  • western blot; chicken; fig 1
Burgess S, Peset I, Joseph N, Cavazza T, Vernos I, Pfuhl M, et al. Aurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle Assembly. PLoS Genet. 2015;11:e1005345 pubmed publisher
  • western blot; human; 1:5000; fig 6
Renard H, Simunovic M, Lemière J, Boucrot E, Garcia Castillo M, Arumugam S, et al. Endophilin-A2 functions in membrane scission in clathrin-independent endocytosis. Nature. 2015;517:493-6 pubmed publisher
  • western blot; human
Devadas D, Koithan T, Diestel R, Prank U, Sodeik B, Döhner K. Herpes simplex virus internalization into epithelial cells requires Na+/H+ exchangers and p21-activated kinases but neither clathrin- nor caveolin-mediated endocytosis. J Virol. 2014;88:13378-95 pubmed publisher
  • western blot; human; 1:5000
Rydell G, Renard H, Garcia Castillo M, Dingli F, Loew D, Lamaze C, et al. Rab12 localizes to Shiga toxin-induced plasma membrane invaginations and controls toxin transport. Traffic. 2014;15:772-87 pubmed publisher
  • western blot; rat; 1:10,000; fig 2d
Li P, Fu Z, Zhang Y, Zhang J, Xu C, Ma Y, et al. The clathrin adaptor Numb regulates intestinal cholesterol absorption through dynamic interaction with NPC1L1. Nat Med. 2014;20:80-6 pubmed publisher
  • immunocytochemistry; rat
Hiroyasu S, Ozawa T, Kobayashi H, Ishii M, Aoyama Y, Kitajima Y, et al. Bullous pemphigoid IgG induces BP180 internalization via a macropinocytic pathway. Am J Pathol. 2013;182:828-40 pubmed publisher
  • western blot; human
Henne W, Boucrot E, Meinecke M, Evergren E, Vallis Y, Mittal R, et al. FCHo proteins are nucleators of clathrin-mediated endocytosis. Science. 2010;328:1281-4 pubmed publisher
Ni Y, Zhou N, Xue W, Rong L, Yung W, Lin R, et al. A new role of anterograde motor Kif5b in facilitating large clathrin-coated vesicle mediated endocytosis via regulating clathrin uncoating. Cell Discov. 2018;4:65 pubmed publisher
Martinez Soria N, McKenzie L, Draper J, Ptasinska A, Issa H, Potluri S, et al. The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation. Cancer Cell. 2018;34:626-642.e8 pubmed publisher
Ma M, Robinson P, Chircop M. Sorting nexin 9 recruits clathrin heavy chain to the mitotic spindle for chromosome alignment and segregation. PLoS ONE. 2013;8:e68387 pubmed publisher
Norambuena A, Metz C, Jung J, Silva A, Otero C, Cancino J, et al. Phosphatidic acid induces ligand-independent epidermal growth factor receptor endocytic traffic through PDE4 activation. Mol Biol Cell. 2010;21:2916-29 pubmed publisher
product information
Cat.# :
610500
Brand :
BD Transduction Laboratories
Name :
Clathrin Heavy Chain
Format :
Purified
Clone :
23/Clathrin Heavy Chain
Isotype :
Ms IgG 1
React :
Hu , Ms , Rat , Dog , Chick
Conc :
250 µg/ml
Apps :
Bioimg , IF , IHC , IP , WB
Size :
150 µg
Status :
RUO
more info or order :
company information