product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Hsp90
catalog :
610419
quantity :
150 µg
price :
415.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
68/Hsp90
reactivity :
human, mouse, rat, dogs, chicken
application :
western blot, immunocytochemistry, immunoprecipitation, other
more info or order :
citations: 50
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:2500; loading ...; fig 2j
Yao F, Zhou Z, Kim J, Hang Q, Xiao Z, Ton B, et al. SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity. Nat Commun. 2018;9:2269 pubmed publisher
  • western blot; human; 1:4000; fig 3b
Hsieh W, Hsu T, Chang Y, Lai M. IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells. Nat Commun. 2018;9:463 pubmed publisher
  • western blot; mouse; loading ...; fig s5h
Rogers Z, McFarland C, Winters I, Naranjo S, Chuang C, Petrov D, et al. A quantitative and multiplexed approach to uncover the fitness landscape of tumor suppression in vivo. Nat Methods. 2017;14:737-742 pubmed publisher
  • western blot; human; loading ...
Shizu R, Osabe M, Perera L, Moore R, Sueyoshi T, Negishi M. Phosphorylated Nuclear Receptor CAR Forms a Homodimer To Repress Its Constitutive Activity for Ligand Activation. Mol Cell Biol. 2017;37: pubmed publisher
  • western blot; mouse; loading ...; fig 6b
Yamauchi T, Nishiyama M, Moroishi T, Kawamura A, Nakayama K. FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells. Mol Cell Biol. 2017;37: pubmed publisher
  • western blot; human; loading ...; fig s6c
Matsumoto A, Pasut A, Matsumoto M, Yamashita R, Fung J, Monteleone E, et al. mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide. Nature. 2017;541:228-232 pubmed publisher
  • western blot; dogs; 1:500; loading ...; fig 3
Graner A, Hellwinkel J, Lencioni A, Madsen H, Harland T, Marchando P, et al. HSP90 inhibitors in the context of heat shock and the unfolded protein response: effects on a primary canine pulmonary adenocarcinoma cell line. Int J Hyperthermia. 2017;33:303-317 pubmed publisher
  • western blot; human; 1:5000; loading ...; fig s2a
Chaudhury A, Cheema S, Fachini J, Kongchan N, Lu G, Simon L, et al. CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT. Nat Commun. 2016;7:13362 pubmed publisher
  • western blot; mouse; loading ...; fig 2k
Jayapal S, Ang H, Wang C, Bisteau X, Caldez M, Xuan G, et al. Cyclin A2 regulates erythrocyte morphology and numbers. Cell Cycle. 2016;15:3070-3081 pubmed
  • western blot; mouse; fig 3
Diril M, Bisteau X, Kitagawa M, Caldez M, Wee S, Gunaratne J, et al. Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint. PLoS Genet. 2016;12:e1006310 pubmed publisher
  • western blot; mouse; 1:1000; fig 7f
Aryal B, Rotllan N, Araldi E, Ramírez C, He S, Chousterman B, et al. ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression. Nat Commun. 2016;7:12313 pubmed publisher
  • western blot; human; loading ...; fig 4h
Galloway A, Saveliev A, Łukasiak S, Hodson D, Bolland D, Balmanno K, et al. RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence. Science. 2016;352:453-9 pubmed publisher
  • western blot; human; fig 2
Okumura F, Uematsu K, Byrne S, Hirano M, Joo Okumura A, Nishikimi A, et al. Parallel Regulation of von Hippel-Lindau Disease by pVHL-Mediated Degradation of B-Myb and Hypoxia-Inducible Factor ?. Mol Cell Biol. 2016;36:1803-17 pubmed publisher
  • western blot; human; fig 3
Bober J, Olsnes S, Kostas M, Bogacz M, Zakrzewska M, Otlewski J. Identification of new FGF1 binding partners-Implications for its intracellular function. IUBMB Life. 2016;68:242-51 pubmed publisher
  • other; human; loading ...; fig st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  • western blot; mouse; fig 1
Moriwaki K, Farias Luz N, Balaji S, De Rosa M, O Donnell C, Gough P, et al. The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages. J Immunol. 2016;196:407-15 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
Robles Oteiza C, Taylor S, Yates T, Cicchini M, Lauderback B, Cashman C, et al. Recombinase-based conditional and reversible gene regulation via XTR alleles. Nat Commun. 2015;6:8783 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 4f
Hussein M, Shrestha E, Ouimet M, Barrett T, Leone S, Moore K, et al. LXR-Mediated ABCA1 Expression and Function Are Modulated by High Glucose and PRMT2. PLoS ONE. 2015;10:e0135218 pubmed publisher
  • western blot; mouse; fig 2
Gurt I, Artsi H, Cohen Kfir E, Hamdani G, Ben Shalom G, Feinstein B, et al. The Sirt1 Activators SRT2183 and SRT3025 Inhibit RANKL-Induced Osteoclastogenesis in Bone Marrow-Derived Macrophages and Down-Regulate Sirt3 in Sirt1 Null Cells. PLoS ONE. 2015;10:e0134391 pubmed publisher
  • western blot; mouse; fig 5
Chiou S, Winters I, Wang J, Naranjo S, Dudgeon C, Tamburini F, et al. Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing. Genes Dev. 2015;29:1576-85 pubmed publisher
  • western blot; mouse; 1:1000
Ohno M, Kanayama T, Moore R, Ray M, Negishi M. The roles of co-chaperone CCRP/DNAJC7 in Cyp2b10 gene activation and steatosis development in mouse livers. PLoS ONE. 2014;9:e115663 pubmed publisher
  • western blot; human
Ohoka N, Nagai K, Hattori T, Okuhira K, Shibata N, Cho N, et al. Cancer cell death induced by novel small molecules degrading the TACC3 protein via the ubiquitin-proteasome pathway. Cell Death Dis. 2014;5:e1513 pubmed publisher
  • western blot; human; 1:3000; fig 2
Zhang P, Wei Y, Wang L, Debeb B, Yuan Y, Zhang J, et al. ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1. Nat Cell Biol. 2014;16:864-75 pubmed publisher
  • western blot; human
Yamauchi T, Nishiyama M, Moroishi T, Yumimoto K, Nakayama K. MDM2 mediates nonproteolytic polyubiquitylation of the DEAD-Box RNA helicase DDX24. Mol Cell Biol. 2014;34:3321-40 pubmed publisher
  • western blot; human
Kitagawa K, Shibata K, Matsumoto A, Matsumoto M, Ohhata T, Nakayama K, et al. Fbw7 targets GATA3 through cyclin-dependent kinase 2-dependent proteolysis and contributes to regulation of T-cell development. Mol Cell Biol. 2014;34:2732-44 pubmed
  • western blot; human
Moroishi T, Yamauchi T, Nishiyama M, Nakayama K. HERC2 targets the iron regulator FBXL5 for degradation and modulates iron metabolism. J Biol Chem. 2014;289:16430-41 pubmed publisher
  • western blot; human; 1:3000
Chen D, Sun Y, Yuan Y, Han Z, Zhang P, Zhang J, et al. miR-100 induces epithelial-mesenchymal transition but suppresses tumorigenesis, migration and invasion. PLoS Genet. 2014;10:e1004177 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 1a
Piao H, Yuan Y, Wang M, Sun Y, Liang H, Ma L. ?-catenin acts as a tumour suppressor in E-cadherin-negative basal-like breast cancer by inhibiting NF-?B signalling. Nat Cell Biol. 2014;16:245-54 pubmed publisher
  • western blot; mouse; 1:3000
Danielson L, Park D, Rotllan N, Chamorro Jorganes A, Guijarro M, Fernandez Hernando C, et al. Cardiovascular dysregulation of miR-17-92 causes a lethal hypertrophic cardiomyopathy and arrhythmogenesis. FASEB J. 2013;27:1460-7 pubmed publisher
  • western blot; human; 1:1000; fig 7
Krzysik Walker S, González Mariscal I, Scheibye Knudsen M, Indig F, Bernier M. The biarylpyrazole compound AM251 alters mitochondrial physiology via proteolytic degradation of ERR?. Mol Pharmacol. 2013;83:157-66 pubmed publisher
  • western blot; mouse; fig 4
Diril M, Ratnacaram C, Padmakumar V, Du T, Wasser M, Coppola V, et al. Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration. Proc Natl Acad Sci U S A. 2012;109:3826-31 pubmed publisher
Hennessy E, van Solingen C, Scacalossi K, Ouimet M, Afonso M, Prins J, et al. The long noncoding RNA CHROME regulates cholesterol homeostasis in primate. Nat Metab. 2019;1:98-110 pubmed publisher
Ishii S, Matsuura A, Itakura E. Identification of a factor controlling lysosomal homeostasis using a novel lysosomal trafficking probe. Sci Rep. 2019;9:11635 pubmed publisher
Chino H, Hatta T, Natsume T, Mizushima N. Intrinsically Disordered Protein TEX264 Mediates ER-phagy. Mol Cell. 2019;74:909-921.e6 pubmed publisher
Muto Y, Moroishi T, Ichihara K, Nishiyama M, Shimizu H, Eguchi H, et al. Disruption of FBXL5-mediated cellular iron homeostasis promotes liver carcinogenesis. J Exp Med. 2019;216:950-965 pubmed publisher
Aryal B, Singh A, Zhang X, Varela L, Rotllan N, Goedeke L, et al. Absence of ANGPTL4 in adipose tissue improves glucose tolerance and attenuates atherogenesis. JCI Insight. 2018;3: pubmed publisher
Hong Z, Pedersen N, Wang L, Torgersen M, Stenmark H, Raiborg C. PtdIns3P controls mTORC1 signaling through lysosomal positioning. J Cell Biol. 2017;216:4217-4233 pubmed publisher
Windpassinger C, Piard J, Bonnard C, Alfadhel M, Lim S, Bisteau X, et al. CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays. Am J Hum Genet. 2017;101:391-403 pubmed publisher
Payen V, Hsu M, Rädecke K, Wyart E, Vazeille T, Bouzin C, et al. Monocarboxylate Transporter MCT1 Promotes Tumor Metastasis Independently of Its Activity as a Lactate Transporter. Cancer Res. 2017;77:5591-5601 pubmed publisher
Soto Feliciano Y, Bartlebaugh J, Liu Y, Sanchez Rivera F, Bhutkar A, Weintraub A, et al. PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes. Genes Dev. 2017;31:973-989 pubmed publisher
Rwigemera A, Joao F, Delbes G. Fetal testis organ culture reproduces the dynamics of epigenetic reprogramming in rat gonocytes. Epigenetics Chromatin. 2017;10:19 pubmed publisher
Artibani M, Sims A, Slight J, Aitken S, Thornburn A, Muir M, et al. WT1 expression in breast cancer disrupts the epithelial/mesenchymal balance of tumour cells and correlates with the metabolic response to docetaxel. Sci Rep. 2017;7:45255 pubmed publisher
Chuang C, Greenside P, Rogers Z, Brady J, Yang D, Ma R, et al. Molecular definition of a metastatic lung cancer state reveals a targetable CD109-Janus kinase-Stat axis. Nat Med. 2017;23:291-300 pubmed publisher
Van Hée V, Labar D, Dehon G, Grasso D, Grégoire V, Muccioli G, et al. Radiosynthesis and validation of (±)-[18F]-3-fluoro-2-hydroxypropionate ([18F]-FLac) as a PET tracer of lactate to monitor MCT1-dependent lactate uptake in tumors. Oncotarget. 2017;8:24415-24428 pubmed publisher
Rentas S, Holzapfel N, Belew M, Pratt G, Voisin V, Wilhelm B, et al. Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells. Nature. 2016;532:508-511 pubmed publisher
Cowley D, Pandya K, Khan I, Kerwin J, Owen K, Griner E. Registered report: A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. elife. 2015;4: pubmed publisher
Dyve Lingelem A, Hjelseth I, Simm R, Torgersen M, Sandvig K. Geldanamycin Enhances Retrograde Transport of Shiga Toxin in HEp-2 Cells. PLoS ONE. 2015;10:e0129214 pubmed publisher
Sletten T, Kostas M, Bober J, Sorensen V, Yadollahi M, Olsnes S, et al. Nucleolin regulates phosphorylation and nuclear export of fibroblast growth factor 1 (FGF1). PLoS ONE. 2014;9:e90687 pubmed publisher
Baselga Escudero L, Bladé C, Ribas Latre A, Casanova E, Suarez M, Torres J, et al. Resveratrol and EGCG bind directly and distinctively to miR-33a and miR-122 and modulate divergently their levels in hepatic cells. Nucleic Acids Res. 2014;42:882-92 pubmed publisher
Marconett C, Sundar S, Poindexter K, Stueve T, Bjeldanes L, Firestone G. Indole-3-carbinol triggers aryl hydrocarbon receptor-dependent estrogen receptor (ER)alpha protein degradation in breast cancer cells disrupting an ERalpha-GATA3 transcriptional cross-regulatory loop. Mol Biol Cell. 2010;21:1166-77 pubmed publisher
product information
Cat.# :
610419
Brand :
BD Transduction Laboratories
Name :
Hsp90
Format :
Purified
Clone :
68/Hsp90
Isotype :
Ms IgG 1
React :
Hu , Ms , Rat , Dog , Chick
Conc :
250 µg/ml
Apps :
IF , IP , WB
Size :
150 µg
Status :
RUO
List Price :
415.00 USD
more info or order :
company information