product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Hsp90
catalog :
610418
quantity :
50 µg
price :
207.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
68/Hsp90
reactivity :
human, mouse, rat, dogs, chicken
application :
western blot, immunocytochemistry, immunoprecipitation, other
more info or order :
citations: 67
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 1d
Jachimowicz R, Beleggia F, Isensee J, Velpula B, Goergens J, Bustos M, et al. UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors. Cell. 2019;176:505-519.e22 pubmed publisher
  • western blot; human; loading ...; fig 1f
Rausch V, Bostrom J, Park J, Bravo I, Feng Y, Hay D, et al. The Hippo Pathway Regulates Caveolae Expression and Mediates Flow Response via Caveolae. Curr Biol. 2019;29:242-255.e6 pubmed publisher
  • western blot; human; loading ...; fig s11c
Bigenzahn J, Collu G, Kartnig F, Pieraks M, Vladimer G, Heinz L, et al. LZTR1 is a regulator of RAS ubiquitination and signaling. Science. 2018;362:1171-1177 pubmed publisher
  • western blot; rat; fig 1d
Rippe C, Zhu B, Krawczyk K, Bavel E, Albinsson S, Sjölund J, et al. Hypertension reduces soluble guanylyl cyclase expression in the mouse aorta via the Notch signaling pathway. Sci Rep. 2017;7:1334 pubmed publisher
  • western blot; mouse; 1:5000; loading ...; fig 1b
Melville Z, Hernández Ochoa E, Pratt S, Liu Y, Pierce A, Wilder P, et al. The Activation of Protein Kinase A by the Calcium-Binding Protein S100A1 Is Independent of Cyclic AMP. Biochemistry. 2017;56:2328-2337 pubmed publisher
  • western blot; human; 1:1000; fig 6b
Stefanowicz D, Ullah J, Lee K, Shaheen F, Olumese E, Fishbane N, et al. Epigenetic modifying enzyme expression in asthmatic airway epithelial cells and fibroblasts. BMC Pulm Med. 2017;17:24 pubmed publisher
  • western blot; mouse; loading ...; fig 1c
Stein S, Lemos V, Xu P, Demagny H, Wang X, Ryu D, et al. Impaired SUMOylation of nuclear receptor LRH-1 promotes nonalcoholic fatty liver disease. J Clin Invest. 2017;127:583-592 pubmed publisher
  • western blot; human; loading ...; fig 1b
Zhao B, Hu W, Kumar S, Gonyo P, Rana U, Liu Z, et al. The Nogo-B receptor promotes Ras plasma membrane localization and activation. Oncogene. 2017;36:3406-3416 pubmed publisher
  • western blot; rat; 1:2000; fig 7c
Grossi M, Bhattachariya A, Nordström I, Turczynska K, Svensson D, Albinsson S, et al. Pyk2 inhibition promotes contractile differentiation in arterial smooth muscle. J Cell Physiol. 2017;232:3088-3102 pubmed publisher
  • western blot; rat; fig 3a
  • western blot; mouse; fig 9h
Krawczyk K, Ekman M, Rippe C, Grossi M, Nilsson B, Albinsson S, et al. Assessing the contribution of thrombospondin-4 induction and ATF6? activation to endoplasmic reticulum expansion and phenotypic modulation in bladder outlet obstruction. Sci Rep. 2016;6:32449 pubmed publisher
  • western blot; human; loading ...; fig 4h
Galloway A, Saveliev A, Łukasiak S, Hodson D, Bolland D, Balmanno K, et al. RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence. Science. 2016;352:453-9 pubmed publisher
  • western blot; human; loading ...; fig 5e
Bigenzahn J, Fauster A, Rebsamen M, Kandasamy R, Scorzoni S, Vladimer G, et al. An Inducible Retroviral Expression System for Tandem Affinity Purification Mass-Spectrometry-Based Proteomics Identifies Mixed Lineage Kinase Domain-like Protein (MLKL) as an Heat Shock Protein 90 (HSP90) Client. Mol Cell Proteomics. 2016;15:1139-50 pubmed
  • other; human; loading ...; fig st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  • western blot; mouse; fig 4
Dimitrova N, Gocheva V, Bhutkar A, Resnick R, Jong R, Miller K, et al. Stromal Expression of miR-143/145 Promotes Neoangiogenesis in Lung Cancer Development. Cancer Discov. 2016;6:188-201 pubmed publisher
  • western blot; mouse; fig 1
Moriwaki K, Farias Luz N, Balaji S, De Rosa M, O Donnell C, Gough P, et al. The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages. J Immunol. 2016;196:407-15 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
Robles Oteiza C, Taylor S, Yates T, Cicchini M, Lauderback B, Cashman C, et al. Recombinase-based conditional and reversible gene regulation via XTR alleles. Nat Commun. 2015;6:8783 pubmed publisher
  • western blot; human; fig 2
Joshi A, Barabutis N, Birmpas C, Dimitropoulou C, Thangjam G, Cherian Shaw M, et al. Histone deacetylase inhibitors prevent pulmonary endothelial hyperpermeability and acute lung injury by regulating heat shock protein 90 function. Am J Physiol Lung Cell Mol Physiol. 2015;309:L1410-9 pubmed publisher
  • western blot; human; 1:5000; fig 3a
Ho D, Kim H, Kim J, Sim H, Ahn H, Kim J, et al. Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21(WAF1/CIP1) expression. Mol Brain. 2015;8:54 pubmed publisher
  • western blot; human; fig 2
Ashford A, Dunkley T, Cockerill M, Rowlinson R, Baak L, Gallo R, et al. Identification of DYRK1B as a substrate of ERK1/2 and characterisation of the kinase activity of DYRK1B mutants from cancer and metabolic syndrome. Cell Mol Life Sci. 2016;73:883-900 pubmed publisher
  • western blot; human; fig 1
Krawczyk K, Yao Mattisson I, Ekman M, Oskolkov N, Grantinge R, Kotowska D, et al. Myocardin Family Members Drive Formation of Caveolae. PLoS ONE. 2015;10:e0133931 pubmed publisher
  • western blot; chicken; 1:1000
Ueda S, Kokaji Y, Simizu S, Honda K, Yoshino K, Kamisoyama H, et al. Chicken heat shock protein HSPB1 increases and interacts with αB-crystallin in aged skeletal muscle. Biosci Biotechnol Biochem. 2015;79:1867-75 pubmed publisher
  • western blot; human; fig s6
Lee A, Kranzusch P, Cate J. eIF3 targets cell-proliferation messenger RNAs for translational activation or repression. Nature. 2015;522:111-4 pubmed publisher
  • western blot; human
Clark P, Kim R, Pober J, Kluger M. Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases. PLoS ONE. 2015;10:e0120075 pubmed publisher
  • western blot; mouse; fig 4
Hodgson A, Wier E, Fu K, Sun X, Yu H, Zheng W, et al. Metalloprotease NleC suppresses host NF-κB/inflammatory responses by cleaving p65 and interfering with the p65/RPS3 interaction. PLoS Pathog. 2015;11:e1004705 pubmed publisher
  • western blot; mouse; 1:1000; fig 7
Zeng J, Ekman M, Grossi M, Svensson D, Nilsson B, Jiang C, et al. Vasopressin-induced mouse urethral contraction is modulated by caveolin-1. Eur J Pharmacol. 2015;750:59-65 pubmed publisher
  • western blot; human
Cubeñas Potts C, Srikumar T, Lee C, Osula O, Subramonian D, Zhang X, et al. Identification of SUMO-2/3-modified proteins associated with mitotic chromosomes. Proteomics. 2015;15:763-72 pubmed publisher
  • western blot; mouse
Lo Sasso G, Menzies K, Mottis A, Piersigilli A, Perino A, Yamamoto H, et al. SIRT2 deficiency modulates macrophage polarization and susceptibility to experimental colitis. PLoS ONE. 2014;9:e103573 pubmed publisher
  • western blot; human
Lo Sasso G, Ryu D, Mouchiroud L, Fernando S, Anderson C, Katsyuba E, et al. Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer. PLoS ONE. 2014;9:e102495 pubmed publisher
  • western blot; human; fig 7f
Tam A, Wadsworth S, Dorscheid D, Man S, Sin D. Estradiol increases mucus synthesis in bronchial epithelial cells. PLoS ONE. 2014;9:e100633 pubmed publisher
  • western blot; human
Ballana E, Badia R, Terradas G, Torres Torronteras J, Ruiz A, Pauls E, et al. SAMHD1 specifically affects the antiviral potency of thymidine analog HIV reverse transcriptase inhibitors. Antimicrob Agents Chemother. 2014;58:4804-13 pubmed publisher
  • western blot; mouse; 1:1000
Swärd K, Albinsson S, Rippe C. Arterial dysfunction but maintained systemic blood pressure in cavin-1-deficient mice. PLoS ONE. 2014;9:e92428 pubmed publisher
  • western blot; rat; 1:1000
Ekman M, Uvelius B, Albinsson S, Swärd K. HIF-mediated metabolic switching in bladder outlet obstruction mitigates the relaxing effect of mitochondrial inhibition. Lab Invest. 2014;94:557-68 pubmed publisher
  • western blot; rat; loading ...; fig s3
Fan X, Jin W, Lu J, Wang J, Wang Y. Rapid and reversible knockdown of endogenous proteins by peptide-directed lysosomal degradation. Nat Neurosci. 2014;17:471-80 pubmed publisher
  • western blot; mouse
Swärd K, Sadegh M, Mori M, Erjefalt J, Rippe C. Elevated pulmonary arterial pressure and altered expression of Ddah1 and Arg1 in mice lacking cavin-1/PTRF. Physiol Rep. 2013;1:e00008 pubmed publisher
  • western blot; human; fig 5
Wan F, Weaver A, Gao X, Bern M, Hardwidge P, Lenardo M. IKK? phosphorylation regulates RPS3 nuclear translocation and NF-?B function during infection with Escherichia coli strain O157:H7. Nat Immunol. 2011;12:335-43 pubmed publisher
  • western blot; human
Zhong X, Ding J, Adams J, Ghosh G, Fu X. Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones. Genes Dev. 2009;23:482-95 pubmed publisher
D Amico D, Mottis A, Potenza F, Sorrentino V, Li H, Romani M, et al. The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging. Mol Cell. 2019;73:775-787.e10 pubmed publisher
Dahlmans D, Houzelle A, Andreux P, Wang X, Jorgensen J, Moullan N, et al. MicroRNA-382 silencing induces a mitonuclear protein imbalance and activates the mitochondrial unfolded protein response in muscle cells. J Cell Physiol. 2019;234:6601-6610 pubmed publisher
Katsyuba E, Mottis A, Zietak M, De Franco F, van der Velpen V, Gariani K, et al. De novo NAD+ synthesis enhances mitochondrial function and improves health. Nature. 2018;563:354-359 pubmed publisher
Krawczyk K, Skovsted G, Perisic L, Dreier R, Berg J, Hedin U, et al. Expression of endothelin type B receptors (EDNRB) on smooth muscle cells is controlled by MKL2, ternary complex factors and actin dynamics. Am J Physiol Cell Physiol. 2018;: pubmed publisher
Zhu B, Rippe C, Holmberg J, Zeng S, Perisic L, Albinsson S, et al. Nexilin/NEXN controls actin polymerization in smooth muscle and is regulated by myocardin family coactivators and YAP. Sci Rep. 2018;8:13025 pubmed publisher
St Martin A, Salamango D, Serebrenik A, Shaban N, Brown W, Donati F, et al. A fluorescent reporter for quantification and enrichment of DNA editing by APOBEC-Cas9 or cleavage by Cas9 in living cells. Nucleic Acids Res. 2018;46:e84 pubmed publisher
Petti L, Marlatt S, Luo Y, Scheideman E, Shelar A, DiMaio D. Regulation of C-C chemokine receptor 5 (CCR5) stability by Lys197 and by transmembrane protein aptamers that target it for lysosomal degradation. J Biol Chem. 2018;293:8787-8801 pubmed publisher
Chrysanthou S, Senner C, Woods L, Fineberg E, Okkenhaug H, Burge S, et al. A Critical Role of TET1/2 Proteins in Cell-Cycle Progression of Trophoblast Stem Cells. Stem Cell Reports. 2018;10:1355-1368 pubmed publisher
Peretz L, Besser E, Hajbi R, Casden N, Ziv D, Kronenberg N, et al. Combined shRNA over CRISPR/cas9 as a methodology to detect off-target effects and a potential compensatory mechanism. Sci Rep. 2018;8:93 pubmed publisher
Krawczyk K, Hansson J, Nilsson H, Krawczyk K, Swärd K, Johansson M. Injury induced expression of caveolar proteins in human kidney tubules - role of megakaryoblastic leukemia 1. BMC Nephrol. 2017;18:320 pubmed publisher
Garcia Vidal E, Castellví M, Pujantell M, Badia R, Jou A, Gomez L, et al. Evaluation of the Innate Immune Modulator Acitretin as a Strategy To Clear the HIV Reservoir. Antimicrob Agents Chemother. 2017;61: pubmed publisher
Quirós P, Prado M, Zamboni N, D Amico D, Williams R, Finley D, et al. Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals. J Cell Biol. 2017;216:2027-2045 pubmed publisher
Lee J, Koehler J, Yusta B, Bahrami J, Matthews D, Rafii M, et al. Enteroendocrine-derived glucagon-like peptide-2 controls intestinal amino acid transport. Mol Metab. 2017;6:245-255 pubmed publisher
Lee A, Kranzusch P, Doudna J, Cate J. eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation. Nature. 2016;536:96-9 pubmed
Aryal B, Rotllan N, Araldi E, Ramírez C, He S, Chousterman B, et al. ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression. Nat Commun. 2016;7:12313 pubmed publisher
Rentas S, Holzapfel N, Belew M, Pratt G, Voisin V, Wilhelm B, et al. Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells. Nature. 2016;532:508-511 pubmed publisher
Corcelle Termeau E, Vindeløv S, Hämälistö S, Mograbi B, Keldsbo A, Bräsen J, et al. Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure. Autophagy. 2016;12:833-49 pubmed publisher
Goedeke L, Rotllan N, Canfrán Duque A, Aranda J, Ramírez C, Araldi E, et al. MicroRNA-148a regulates LDL receptor and ABCA1 expression to control circulating lipoprotein levels. Nat Med. 2015;21:1280-9 pubmed publisher
Grossi M, Rippe C, Sathanoori R, Swärd K, Forte A, Erlinge D, et al. Vascular smooth muscle cell proliferation depends on caveolin-1-regulated polyamine uptake. Biosci Rep. 2014;34:e00153 pubmed publisher
Takahashi R, Takeshita F, Honma K, Ono M, Kato K, Ochiya T. Ribophorin II regulates breast tumor initiation and metastasis through the functional suppression of GSK3?. Sci Rep. 2013;3:2474 pubmed publisher
Turczynska K, Bhattachariya A, Säll J, Göransson O, Swärd K, Hellstrand P, et al. Stretch-sensitive down-regulation of the miR-144/451 cluster in vascular smooth muscle and its role in AMP-activated protein kinase signaling. PLoS ONE. 2013;8:e65135 pubmed publisher
Leung C, Shaheen F, Bernatchez P, Hackett T. Expression of myoferlin in human airway epithelium and its role in cell adhesion and zonula occludens-1 expression. PLoS ONE. 2012;7:e40478 pubmed publisher
Hensen S, Heldens L, van Enckevort C, van Genesen S, Pruijn G, Lubsen N. Heat shock factor 1 is inactivated by amino acid deprivation. Cell Stress Chaperones. 2012;17:743-55 pubmed publisher
Heldens L, van Genesen S, Hanssen L, Hageman J, Kampinga H, Lubsen N. Protein refolding in peroxisomes is dependent upon an HSF1-regulated function. Cell Stress Chaperones. 2012;17:603-13 pubmed publisher
Krzykowska Petitjean K, Małecki J, Bentke A, Ostrowska B, Laidler P. Tipifarnib and tanespimycin show synergic proapoptotic activity in U937 cells. J Cancer Res Clin Oncol. 2012;138:537-44 pubmed publisher
Morishita D, Takami M, Yoshikawa S, Katayama R, Sato S, Kukimoto Niino M, et al. Cell-permeable carboxyl-terminal p27(Kip1) peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase. J Biol Chem. 2011;286:2681-8 pubmed publisher
Hartley T, Siva M, Lai E, Teodoro T, Zhang L, Volchuk A. Endoplasmic reticulum stress response in an INS-1 pancreatic beta-cell line with inducible expression of a folding-deficient proinsulin. BMC Cell Biol. 2010;11:59 pubmed publisher
Heldens L, Dirks R, Hensen S, Onnekink C, van Genesen S, Rustenburg F, et al. Co-chaperones are limiting in a depleted chaperone network. Cell Mol Life Sci. 2010;67:4035-48 pubmed publisher
Dirks R, van Geel R, Hensen S, van Genesen S, Lubsen N. Manipulating heat shock factor-1 in Xenopus tadpoles: neuronal tissues are refractory to exogenous expression. PLoS ONE. 2010;5:e10158 pubmed publisher
Sensintaffar J, Scott F, Peach R, Hager J. XIAP is not required for human tumor cell survival in the absence of an exogenous death signal. BMC Cancer. 2010;10:11 pubmed publisher
Omran H, Kobayashi D, Olbrich H, Tsukahara T, Loges N, Hagiwara H, et al. Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins. Nature. 2008;456:611-6 pubmed publisher
product information
Cat.# :
610418
Brand :
BD Transduction Laboratories
Name :
Hsp90
Format :
Purified
Clone :
68/Hsp90
Isotype :
Ms IgG 1
React :
Hu , Ms , Rat , Dog , Chick
Conc :
250 µg/ml
Apps :
IF , IP , WB
Size :
50 µg
Status :
RUO
List Price :
207.00 USD
more info or order :
company information