product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Ran
catalog :
610340
quantity :
50 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
20/Ran
reactivity :
human, mouse, rat, dogs, chicken
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, other
more info or order :
citations: 21
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...; fig s8e
Van Alstyne M, Tattoli I, Delestrée N, Recinos Y, Workman E, Shihabuddin L, et al. Gain of toxic function by long-term AAV9-mediated SMN overexpression in the sensorimotor circuit. Nat Neurosci. 2021;24:930-940 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 8d
Gasset Rosa F, Lu S, Yu H, Chen C, Melamed Z, Guo L, et al. Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death. Neuron. 2019;102:339-357.e7 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig s1b
Desrochers L, Bordeleau F, Reinhart King C, Cerione R, Antonyak M. Microvesicles provide a mechanism for intercellular communication by embryonic stem cells during embryo implantation. Nat Commun. 2016;7:11958 pubmed publisher
  • western blot; human; fig 5
Cekan P, Hasegawa K, Pan Y, Tubman E, Odde D, Chen J, et al. RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage-induced cell senescence. Mol Biol Cell. 2016;27:1346-57 pubmed publisher
  • other; human; loading ...; fig st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  • western blot; human; 1:10,000; fig 4
  • western blot; mouse; 1:1000; fig 4
Cohen D, Won K, Nguyen N, Lazar M, Chen C, Steger D. ATF4 licenses C/EBPβ activity in human mesenchymal stem cells primed for adipogenesis. elife. 2015;4:e06821 pubmed publisher
  • western blot; human; 1:10,000; fig 1
Khuperkar D, Helen M, Magre I, Joseph J. Inter-cellular transport of ran GTPase. PLoS ONE. 2015;10:e0125506 pubmed publisher
  • western blot; mouse
DiSpirito J, Fang B, Wang F, Lazar M. Pruning of the adipocyte peroxisome proliferator-activated receptor ? cistrome by hematopoietic master regulator PU.1. Mol Cell Biol. 2013;33:3354-64 pubmed publisher
  • western blot; human
Pavlova N, Pallasch C, Elia A, Braun C, Westbrook T, Hemann M, et al. A role for PVRL4-driven cell-cell interactions in tumorigenesis. elife. 2013;2:e00358 pubmed publisher
  • western blot; mouse
Freudenberg J, Ghosh S, Lackford B, Yellaboina S, Zheng X, Li R, et al. Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity. Nucleic Acids Res. 2012;40:3364-77 pubmed publisher
Yuen G, Khan F, Gao S, Stommel J, Batchelor E, Wu X, et al. CRISPR/Cas9-mediated gene knockout is insensitive to target copy number but is dependent on guide RNA potency and Cas9/sgRNA threshold expression level. Nucleic Acids Res. 2017;45:12039-12053 pubmed publisher
Soccio R, Li Z, Chen E, Foong Y, Benson K, DiSpirito J, et al. Targeting PPAR? in the epigenome rescues genetic metabolic defects in mice. J Clin Invest. 2017;127:1451-1462 pubmed publisher
Prokesch A, Graef F, Madl T, Kahlhofer J, Heidenreich S, Schümann A, et al. Liver p53 is stabilized upon starvation and required for amino acid catabolism and gluconeogenesis. FASEB J. 2017;31:732-742 pubmed publisher
Hsu T, Simon L, Neill N, Marcotte R, Sayad A, Bland C, et al. The spliceosome is a therapeutic vulnerability in MYC-driven cancer. Nature. 2015;525:384-8 pubmed publisher
Yang W, Cooke M, Duckett C, Yang X, Dorsey J. Distinctive effects of the cellular inhibitor of apoptosis protein c-IAP2 through stabilization by XIAP in glioblastoma multiforme cells. Cell Cycle. 2014;13:992-1005 pubmed publisher
Sitnick M, Basantani M, Cai L, Schoiswohl G, Yazbeck C, Distefano G, et al. Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity. Diabetes. 2013;62:3350-61 pubmed publisher
Comstock C, Augello M, Goodwin J, de Leeuw R, Schiewer M, Ostrander W, et al. Targeting cell cycle and hormone receptor pathways in cancer. Oncogene. 2013;32:5481-91 pubmed publisher
Feeley E, Sims J, John S, Chin C, Pertel T, Chen L, et al. IFITM3 inhibits influenza A virus infection by preventing cytosolic entry. PLoS Pathog. 2011;7:e1002337 pubmed publisher
Dishinger J, Kee H, Jenkins P, Fan S, Hurd T, Hammond J, et al. Ciliary entry of the kinesin-2 motor KIF17 is regulated by importin-beta2 and RanGTP. Nat Cell Biol. 2010;12:703-10 pubmed publisher
Medendorp K, van Groningen J, Vreede L, Hetterschijt L, van den Hurk W, de Bruijn D, et al. The mitotic arrest deficient protein MAD2B interacts with the small GTPase RAN throughout the cell cycle. PLoS ONE. 2009;4:e7020 pubmed publisher
Sekiguchi T, Hayano T, Yanagida M, Takahashi N, Nishimoto T. NOP132 is required for proper nucleolus localization of DEAD-box RNA helicase DDX47. Nucleic Acids Res. 2006;34:4593-608 pubmed
product information
Cat.# :
610340
Brand :
BD Transduction Laboratories
Name :
Ran
Format :
Purified
Clone :
20/Ran
Isotype :
Ms IgG 2a
React :
Hu , Ms , Rat , Dog , Chick
Conc :
250 µg/ml
Apps :
IF , IHC , IP , WB
Size :
50 µg
Status :
RUO
more info or order :
company information