product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Munc-18
catalog :
610336
quantity :
50 µg
price :
207.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
31/Munc-18
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, western blot knockout validation
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; fig 2b
  • immunocytochemistry; human; fig 8
Chai Y, Sierecki E, Tomatis V, Gormal R, Giles N, Morrow I, et al. Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation. J Cell Biol. 2016;214:705-18 pubmed publisher
  • western blot; human; loading ...; fig 3b
Shen C, Liu Y, Yu H, Gulbranson D, Kogut I, Bilousova G, et al. The N-peptide-binding mode is critical to Munc18-1 function in synaptic exocytosis. J Biol Chem. 2018;293:18309-18317 pubmed publisher
  • western blot; rat; 1:1000; fig 2
Craig T, Anderson D, Evans A, Girach F, Henley J. SUMOylation of Syntaxin1A regulates presynaptic endocytosis. Sci Rep. 2015;5:17669 pubmed publisher
Yu H, Shen C, Liu Y, Menasche B, Ouyang Y, Stowell M, et al. SNARE zippering requires activation by SNARE-like peptides in Sec1/Munc18 proteins. Proc Natl Acad Sci U S A. 2018;115:E8421-E8429 pubmed publisher
Santos T, Wierda K, Broeke J, Toonen R, Verhage M. Early Golgi Abnormalities and Neurodegeneration upon Loss of Presynaptic Proteins Munc18-1, Syntaxin-1, or SNAP-25. J Neurosci. 2017;37:4525-4539 pubmed publisher
Smyth A, Yang L, Martin K, Hamilton C, Lu W, Cousin M, et al. Munc18-1 protein molecules move between membrane molecular depots distinct from vesicle docking sites. J Biol Chem. 2013;288:5102-13 pubmed publisher
product information
Cat.# :
610336
Brand :
BD Transduction Laboratories
Name :
Munc-18
Format :
Purified
Clone :
31/Munc-18
Isotype :
Ms IgG 1
React :
Hu , Ms , Rat
Conc :
250 µg/ml
Apps :
IF , IHC , IP , WB
Size :
50 µg
Status :
RUO
List Price :
207.00 USD
more info or order :
company information