product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Ral A
catalog :
610222
quantity :
150 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
8/Ral A
reactivity :
human, mouse, rat, dogs, chicken, fruit fly
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry knockout validation
more info or order :
citations: 12
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; fruit fly ; loading ...; fig 1a
  • immunohistochemistry knockout validation; mouse; loading ...; fig 3i
Johansson J, Nászai M, Hodder M, Pickering K, Miller B, Ridgway R, et al. RAL GTPases Drive Intestinal Stem Cell Function and Regeneration through Internalization of WNT Signalosomes. Cell Stem Cell. 2019;24:592-607.e7 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 3b
Ghoroghi S, Mary B, Larnicol A, Asokan N, Klein A, Osmani N, et al. Ral GTPases promote breast cancer metastasis by controlling biogenesis and organ targeting of exosomes. elife. 2021;10: pubmed publisher
  • immunocytochemistry; rat; 1:50; loading ...; fig 1g
Galino J, Cervellini I, Zhu N, Stöberl N, Hütte M, Fricker F, et al. RalGTPases contribute to Schwann cell repair after nerve injury via regulation of process formation. J Cell Biol. 2019;: pubmed publisher
  • western blot; human; 1:1000; fig 6
O Santos A, Parrini M, Camonis J. RalGPS2 Is Essential for Survival and Cell Cycle Progression of Lung Cancer Cells Independently of Its Established Substrates Ral GTPases. PLoS ONE. 2016;11:e0154840 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
  • western blot; mouse
Peschard P, McCarthy A, Leblanc Dominguez V, Yeo M, Guichard S, Stamp G, et al. Genetic deletion of RALA and RALB small GTPases reveals redundant functions in development and tumorigenesis. Curr Biol. 2012;22:2063-8 pubmed publisher
Hinsch C, Venkata J, Hsu T, Dammai V. Controlled Plasma Membrane Delivery of FGFR1 and Modulation of Signaling by a Novel Regulated Anterograde RTK Transport Pathway. Cancers (Basel). 2023;15: pubmed publisher
Beel S, Kolloch L, Apken L, Jürgens L, Bolle A, Sudhof N, et al. κB-Ras and Ral GTPases regulate acinar to ductal metaplasia during pancreatic adenocarcinoma development and pancreatitis. Nat Commun. 2020;11:3409 pubmed publisher
Wersäll A, Williams C, Brown E, Iannitti T, Williams N, Poole A. Mouse Platelet Ral GTPases Control P-Selectin Surface Expression, Regulating Platelet-Leukocyte Interaction. Arterioscler Thromb Vasc Biol. 2018;38:787-800 pubmed publisher
Bettoun A, Joffre C, Zago G, Surdez D, Vallerand D, Gundogdu R, et al. Mitochondrial clearance by the STK38 kinase supports oncogenic Ras-induced cell transformation. Oncotarget. 2016;7:44142-44160 pubmed publisher
Reilly S, Ahmadian M, Zamarron B, Chang L, Uhm M, Poirier B, et al. A subcutaneous adipose tissue-liver signalling axis controls hepatic gluconeogenesis. Nat Commun. 2015;6:6047 pubmed publisher
Sadacca L, Bruno J, Wen J, Xiong W, McGraw T. Specialized sorting of GLUT4 and its recruitment to the cell surface are independently regulated by distinct Rabs. Mol Biol Cell. 2013;24:2544-57 pubmed publisher
Reilly S, Chiang S, Decker S, Chang L, Uhm M, Larsen M, et al. An inhibitor of the protein kinases TBK1 and IKK-? improves obesity-related metabolic dysfunctions in mice. Nat Med. 2013;19:313-21 pubmed publisher
product information
Cat.# :
610222
Brand :
BD Transduction Laboratories
Name :
Ral A
Format :
Purified
Clone :
8/Ral A
Isotype :
Ms IgG 2a
React :
Hu , Ms , Rat , Dog , Chick
Conc :
250 µg/ml
Apps :
IF , IHC(F)* , WB
Size :
150 µg
Status :
RUO
more info or order :
company information