This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Bcl-x
catalog :
610211
quantity :
50 µg
price :
207.00 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, chicken
application :
western blot, immunohistochemistry, immunocytochemistry
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 3i
Pilar Valdecantos M, Prieto Hontoria P, Pardo V, Módol T, Santamaría B, Weber M, et al. Essential role of Nrf2 in the protective effect of lipoic acid against lipoapoptosis in hepatocytes. Free Radic Biol Med. 2015;84:263-278 pubmed publisher
  • western blot; human
Dho S, Deverman B, Lapid C, Manson S, Gan L, Riehm J, et al. Control of cellular Bcl-xL levels by deamidation-regulated degradation. PLoS Biol. 2013;11:e1001588 pubmed publisher
  • western blot; mouse
  • western blot; human
Mobasher M, Gonzalez Rodriguez A, Santamaria B, Ramos S, Martin M, Goya L, et al. Protein tyrosine phosphatase 1B modulates GSK3?/Nrf2 and IGFIR signaling pathways in acetaminophen-induced hepatotoxicity. Cell Death Dis. 2013;4:e626 pubmed publisher
Ishida S, Akiyama H, Umezawa Y, Okada K, Nogami A, Oshikawa G, et al. Mechanisms for mTORC1 activation and synergistic induction of apoptosis by ruxolitinib and BH3 mimetics or autophagy inhibitors in JAK2-V617F-expressing leukemic cells including newly established PVTL-2. Oncotarget. 2018;9:26834-26851 pubmed publisher
Dho S, Manson S, Jung S, Lim J, Weintraub S. Bcl-xL deamidation is regulated by multiple ion transporters and is intramolecularly catalyzed. Biochim Biophys Acta Mol Cell Res. 2018;1865:995-1001 pubmed publisher
Santacatterina F, Sánchez Cenizo L, Formentini L, Mobasher M, Casas E, Rueda C, et al. Down-regulation of oxidative phosphorylation in the liver by expression of the ATPase inhibitory factor 1 induces a tumor-promoter metabolic state. Oncotarget. 2016;7:490-508 pubmed publisher
Reiner T, de las Pozas A, Parrondo R, Palenzuela D, Cayuso W, Rai P, et al. Mcl-1 protects prostate cancer cells from cell death mediated by chemotherapy-induced DNA damage. Oncoscience. 2015;2:703-15 pubmed
Nogami A, Oshikawa G, Okada K, Fukutake S, Umezawa Y, Nagao T, et al. FLT3-ITD confers resistance to the PI3K/Akt pathway inhibitors by protecting the mTOR/4EBP1/Mcl-1 pathway through STAT5 activation in acute myeloid leukemia. Oncotarget. 2015;6:9189-205 pubmed
Schaller Schönitz M, Barzan D, Williamson A, Griffiths J, Dallmann I, Battmer K, et al. BCR-ABL affects STAT5A and STAT5B differentially. PLoS ONE. 2014;9:e97243 pubmed publisher
Potter D, Kelly P, Denneny O, Juvin V, Stephens L, Dive C, et al. BMX acts downstream of PI3K to promote colorectal cancer cell survival and pathway inhibition sensitizes to the BH3 mimetic ABT-737. Neoplasia. 2014;16:147-57 pubmed publisher
Parrondo R, de las Pozas A, Reiner T, Perez Stable C. ABT-737, a small molecule Bcl-2/Bcl-xL antagonist, increases antimitotic-mediated apoptosis in human prostate cancer cells. Peerj. 2013;1:e144 pubmed publisher
Reiner T, Parrondo R, de las Pozas A, Palenzuela D, Perez Stable C. Betulinic acid selectively increases protein degradation and enhances prostate cancer-specific apoptosis: possible role for inhibition of deubiquitinase activity. PLoS ONE. 2013;8:e56234 pubmed publisher
Valverde A, Miranda S, García Ramírez M, Gonzalez Rodriguez A, Hernandez C, Simo R. Proapoptotic and survival signaling in the neuroretina at early stages of diabetic retinopathy. Mol Vis. 2013;19:47-53 pubmed
Martínez Palacián A, del Castillo G, Suárez Causado A, García Álvaro M, de Morena Frutos D, Fernandez M, et al. Mouse hepatic oval cells require Met-dependent PI3K to impair TGF-?-induced oxidative stress and apoptosis. PLoS ONE. 2013;8:e53108 pubmed publisher
Thiel K, Hernandez L, Dassie J, Thiel W, Liu X, Stockdale K, et al. Delivery of chemo-sensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers. Nucleic Acids Res. 2012;40:6319-37 pubmed publisher
product information
Cat.# :
610211
Brand :
BD Transduction Laboratories
Name :
Bcl-x
Format :
Purified
Clone :
Polyclonal
Isotype :
Rab IgG
React :
Hu , Ms , Rat , Dog , Chick
Conc :
250 µg/ml
Apps :
IF , IHC , WB
Size :
50 µg
Status :
RUO
List Price :
207.00 USD
company information