product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
GSK-3
catalog :
610201
quantity :
50 µg
price :
205.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
7/GSK-3b
reactivity :
human, mouse, rat, dog
application :
western blot, immunohistochemistry, immunocytochemistry, other, western blot knockout validation
more info or order :
citations: 27
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; 1:1000; fig 1a
Chen X, Wang R, Liu X, Wu Y, Zhou T, Yang Y, et al. A Chemical-Genetic Approach Reveals the Distinct Roles of GSK3? and GSK3? in Regulating Embryonic Stem Cell Fate. Dev Cell. 2017;43:563-576.e4 pubmed publisher
  • western blot; human; loading ...; fig 7b
  • western blot; rat; loading ...; fig 7b
  • western blot; mouse; loading ...; fig 8c
Nasri I, Bonnet D, Zwarycz B, d Aldebert E, Khou S, Mezghani Jarraya R, et al. PAR2-dependent activation of GSK3? regulates the survival of colon stem/progenitor cells. Am J Physiol Gastrointest Liver Physiol. 2016;311:G221-36 pubmed publisher
  • immunohistochemistry; mouse; 1:500; fig 5d
Itoh Y, Higuchi M, Oishi K, Kishi Y, Okazaki T, Sakai H, et al. PDK1-Akt pathway regulates radial neuronal migration and microtubules in the developing mouse neocortex. Proc Natl Acad Sci U S A. 2016;113:E2955-64 pubmed publisher
  • western blot; rat; 1:2500; fig 4b
Molteni R, Rossetti A, Savino E, Racagni G, Calabrese F. Chronic Mild Stress Modulates Activity-Dependent Transcription of BDNF in Rat Hippocampal Slices. Neural Plast. 2016;2016:2592319 pubmed publisher
  • other; human; loading ...; fig st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  • western blot; human; 1:250; fig 6
Martínez Revollar G, Garay E, Martín Tapia D, Nava P, Huerta M, Lopez Bayghen E, et al. Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways. Exp Cell Res. 2015;339:67-80 pubmed publisher
  • immunocytochemistry; mouse; 1:200; fig 3
Cymerman I, Gozdz A, Urbanska M, Milek J, Dziembowska M, Jaworski J. Structural Plasticity of Dendritic Spines Requires GSK3α and GSK3β. PLoS ONE. 2015;10:e0134018 pubmed publisher
  • western blot; human; fig 3
Reis C, Chen P, Srinivasan S, Aguet F, Mettlen M, Schmid S. Crosstalk between Akt/GSK3β signaling and dynamin-1 regulates clathrin-mediated endocytosis. EMBO J. 2015;34:2132-46 pubmed publisher
  • western blot; mouse; 1:1000; fig 6
Kim A, Park Y, Pan X, Shin K, Kwak S, Bassas A, et al. Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance. Nat Commun. 2015;6:7585 pubmed publisher
  • western blot; mouse
Hu X, Li X, Zhao M, Gottesdiener A, Luo W, Paul S. Tau pathogenesis is promoted by Aβ1-42 but not Aβ1-40. Mol Neurodegener. 2014;9:52 pubmed publisher
  • western blot; mouse; fig 8
Kleinert M, Sylow L, Fazakerley D, Krycer J, Thomas K, Oxbøll A, et al. Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo. Mol Metab. 2014;3:630-41 pubmed publisher
  • western blot; mouse; 1:1000
Wallmen B, Schrempp M, Hecht A. Intrinsic properties of Tcf1 and Tcf4 splice variants determine cell-type-specific Wnt/?-catenin target gene expression. Nucleic Acids Res. 2012;40:9455-69 pubmed publisher
  • western blot; human
Rieger J, Lemke D, Maurer G, Weiler M, Frank B, Tabatabai G, et al. Enzastaurin-induced apoptosis in glioma cells is caspase-dependent and inhibited by BCL-XL. J Neurochem. 2008;106:2436-48 pubmed publisher
Tejeda Muñoz N, Albrecht L, Bui M, De Robertis E. Wnt canonical pathway activates macropinocytosis and lysosomal degradation of extracellular proteins. Proc Natl Acad Sci U S A. 2019;116:10402-10411 pubmed publisher
Albrecht L, Bui M, De Robertis E. Canonical Wnt is inhibited by targeting one-carbon metabolism through methotrexate or methionine deprivation. Proc Natl Acad Sci U S A. 2019;116:2987-2995 pubmed publisher
Agajanian M, Walker M, Axtman A, Ruela de Sousa R, Serafin D, Rabinowitz A, et al. WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop. Cell Rep. 2019;26:79-93.e8 pubmed publisher
Moon S, Kim W, Kim S, Kim Y, Song Y, Bilousov O, et al. Phosphorylation by NLK inhibits YAP-14-3-3-interactions and induces its nuclear localization. EMBO Rep. 2017;18:61-71 pubmed publisher
Kawai M, Nakashima A, Kamada S, Kikkawa U. Midostaurin preferentially attenuates proliferation of triple-negative breast cancer cell lines through inhibition of Aurora kinase family. J Biomed Sci. 2015;22:48 pubmed publisher
Hara T, Hashimoto Y, Akuzawa T, Hirai R, Kobayashi H, Sato K. Rer1 and calnexin regulate endoplasmic reticulum retention of a peripheral myelin protein 22 mutant that causes type 1A Charcot-Marie-Tooth disease. Sci Rep. 2014;4:6992 pubmed publisher
Stoica R, De Vos K, Paillusson S, Mueller S, Sancho R, Lau K, et al. ER-mitochondria associations are regulated by the VAPB-PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43. Nat Commun. 2014;5:3996 pubmed publisher
Takahashi R, Takeshita F, Honma K, Ono M, Kato K, Ochiya T. Ribophorin II regulates breast tumor initiation and metastasis through the functional suppression of GSK3?. Sci Rep. 2013;3:2474 pubmed publisher
Sarfstein R, Friedman Y, Attias Geva Z, Fishman A, Bruchim I, Werner H. Metformin downregulates the insulin/IGF-I signaling pathway and inhibits different uterine serous carcinoma (USC) cells proliferation and migration in p53-dependent or -independent manners. PLoS ONE. 2013;8:e61537 pubmed publisher
Veland I, Montjean R, Eley L, Pedersen L, Schwab A, Goodship J, et al. Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration. PLoS ONE. 2013;8:e60193 pubmed publisher
Bikkavilli R, Malbon C. Arginine methylation of G3BP1 in response to Wnt3a regulates ?-catenin mRNA. J Cell Sci. 2011;124:2310-20 pubmed publisher
Osawa Y, Seki E, Kodama Y, Suetsugu A, Miura K, Adachi M, et al. Acid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP-activated protein kinase suppression. FASEB J. 2011;25:1133-44 pubmed publisher
Weise A, Bruser K, Elfert S, Wallmen B, Wittel Y, Wöhrle S, et al. Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/beta-catenin targets. Nucleic Acids Res. 2010;38:1964-81 pubmed publisher
Prasad C, Rath G, Mathur S, Bhatnagar D, Parshad R, Ralhan R. Expression analysis of E-cadherin, Slug and GSK3beta in invasive ductal carcinoma of breast. BMC Cancer. 2009;9:325 pubmed publisher
product information
Cat.# :
610201
Brand :
BD Transduction Laboratories
Name :
GSK-3
Format :
Purified
Clone :
7/GSK-3b
Isotype :
Ms IgG 1
React :
Hu , Ms , Rat , Dog , Chick
Conc :
250 µg/ml
Apps :
Bioimg , WB
Size :
50 µg
Status :
RUO
List Price :
205.00 USD
more info or order :
company information