product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Stat3
catalog :
610189
quantity :
50 µg
price :
207.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
84/Stat3
reactivity :
human, mouse, rat, dog, chicken
application :
western blot, immunohistochemistry, immunoprecipitation, western blot knockout validation
more info or order :
citations: 17
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; 1:500; fig 2
Yang H, Yamazaki T, Pietrocola F, Zhou H, Zitvogel L, Ma Y, et al. STAT3 Inhibition Enhances the Therapeutic Efficacy of Immunogenic Chemotherapy by Stimulating Type 1 Interferon Production by Cancer Cells. Cancer Res. 2015;75:3812-22 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4c
Granato M, Rizzello C, Gilardini Montani M, Cuomo L, Vitillo M, Santarelli R, et al. Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways. J Nutr Biochem. 2017;41:124-136 pubmed publisher
  • western blot; human; fig 3
Peng H, Cheng Y, Hsu Y, Wu G, Kuo C, Liou J, et al. MPT0B098, a Microtubule Inhibitor, Suppresses JAK2/STAT3 Signaling Pathway through Modulation of SOCS3 Stability in Oral Squamous Cell Carcinoma. PLoS ONE. 2016;11:e0158440 pubmed publisher
  • western blot; human; fig 4
Ardini E, Menichincheri M, Banfi P, Bosotti R, De Ponti C, Pulci R, et al. Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications. Mol Cancer Ther. 2016;15:628-39 pubmed publisher
  • western blot; dog; 1:2000; fig 5
Clemente Vicario F, Alvarez C, ROWELL J, Roy S, London C, Kisseberth W, et al. Human Genetic Relevance and Potent Antitumor Activity of Heat Shock Protein 90 Inhibition in Canine Lung Adenocarcinoma Cell Lines. PLoS ONE. 2015;10:e0142007 pubmed publisher
  • western blot; human; 1:1000; fig 2
Granato M, Gilardini Montani M, Filardi M, Faggioni A, Cirone M. Capsaicin triggers immunogenic PEL cell death, stimulates DCs and reverts PEL-induced immune suppression. Oncotarget. 2015;6:29543-54 pubmed publisher
  • western blot; mouse; 1:2500; loading ...; fig 4d
Sheshadri P, Ashwini A, Jahnavi S, Bhonde R, Prasanna J, Kumar A. Novel role of mitochondrial manganese superoxide dismutase in STAT3 dependent pluripotency of mouse embryonic stem cells. Sci Rep. 2015;5:9516 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig s1c
  • immunohistochemistry; human; 1:200; loading ...; fig 1e
Grabner B, Schramek D, Mueller K, Moll H, Svinka J, Hoffmann T, et al. Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis. Nat Commun. 2015;6:6285 pubmed publisher
  • western blot; mouse
Cansby E, Nerstedt A, Amrutkar M, Durán E, Smith U, Mahlapuu M. Partial hepatic resistance to IL-6-induced inflammation develops in type 2 diabetic mice, while the anti-inflammatory effect of AMPK is maintained. Mol Cell Endocrinol. 2014;393:143-51 pubmed publisher
  • western blot; mouse
Hashimoto M, Nasser H, Chihara T, Suzu S. Macropinocytosis and TAK1 mediate anti-inflammatory to pro-inflammatory macrophage differentiation by HIV-1 Nef. Cell Death Dis. 2014;5:e1267 pubmed publisher
Abdalla B, Li Z, Ouyang H, Jebessa E, Sun T, Yu J, et al. A Novel Dnmt3a1 Transcript Inhibits Adipogenesis. Front Physiol. 2018;9:1270 pubmed publisher
Olesen M, Christiansen J, Petersen S, Jensen P, Paslawski W, Romero Ramos M, et al. CD4 T cells react to local increase of α-synuclein in a pathology-associated variant-dependent manner and modify brain microglia in absence of brain pathology. Heliyon. 2018;4:e00513 pubmed publisher
D Eliseo D, Di Renzo L, Santoni A, Velotti F. Docosahexaenoic acid (DHA) promotes immunogenic apoptosis in human multiple myeloma cells, induces autophagy and inhibits STAT3 in both tumor and dendritic cells. Genes Cancer. 2017;8:426-437 pubmed publisher
Rozo C, Chinenov Y, Maharaj R, Gupta S, Leuenberger L, Kirou K, et al. Targeting the RhoA-ROCK pathway to reverse T-cell dysfunction in SLE. Ann Rheum Dis. 2017;76:740-747 pubmed publisher
Santarelli R, Gonnella R, Di Giovenale G, Cuomo L, Capobianchi A, Granato M, et al. STAT3 activation by KSHV correlates with IL-10, IL-6 and IL-23 release and an autophagic block in dendritic cells. Sci Rep. 2014;4:4241 pubmed publisher
Irtegun S, Wood R, Ormsby A, Mulhern T, Hatters D. Tyrosine 416 is phosphorylated in the closed, repressed conformation of c-Src. PLoS ONE. 2013;8:e71035 pubmed publisher
Kotb A, Hierholzer A, Kemler R. Replacement of E-cadherin by N-cadherin in the mammary gland leads to fibrocystic changes and tumor formation. Breast Cancer Res. 2011;13:R104 pubmed publisher
product information
Cat.# :
610189
Brand :
BD Transduction Laboratories
Name :
Stat3
Format :
Purified
Clone :
84/Stat3
Isotype :
Ms IgG 1
React :
Hu , Ms , Rat , Dog , Chick , Frog
Conc :
250 µg/ml
Apps :
IP , WB
Size :
50 µg
Status :
RUO
List Price :
207.00 USD
more info or order :
company information