product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
PKC
catalog :
610175
quantity :
50 µg
price :
207.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
23/PKC
reactivity :
human, mouse, brown rat, dogs
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, other, western blot knockout validation, immunohistochemistry knockout validation
more info or order :
BD Biosciences product webpage
citations: 10
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry knockout validation; mouse; fig 2
Sugiyama Y, Akimoto K, Robinson M, Ohno S, Quinlan R. A cell polarity protein aPKClambda is required for eye lens formation and growth. Dev Biol. 2009;336:246-56 pubmed publisher
  • western blot knockout validation; mouse; 1:1000
Imai F, Hirai S, Akimoto K, Koyama H, Miyata T, Ogawa M, et al. Inactivation of aPKClambda results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex. Development. 2006;133:1735-44 pubmed
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 3s1a
Bendriem R, Singh S, Aleem A, Antonetti D, Ross M. Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex. elife. 2019;8: pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 6c
  • western blot; human; 1:1000; fig 2a
Phillips E, Lang V, Bohlen J, Bethke F, Puccio L, Tichy D, et al. Targeting atypical protein kinase C iota reduces viability in glioblastoma stem-like cells via a notch signaling mechanism. Int J Cancer. 2016;139:1776-87 pubmed publisher
  • other; human; loading ...; fig st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  • western blot; mouse; fig 2
Yamanaka T, Tosaki A, Kurosawa M, Akimoto K, Hirose T, Ohno S, et al. Loss of aPKC? in differentiated neurons disrupts the polarity complex but does not induce obvious neuronal loss or disorientation in mouse brains. PLoS ONE. 2013;8:e84036 pubmed publisher
Kim K, Chung C, Kim J, Lee D, Cho S, Lee T, et al. Clinical significance of atypical protein kinase C (PKCι and PKCζ) and its relationship with yes-associated protein in lung adenocarcinoma. BMC Cancer. 2019;19:804 pubmed publisher
Halaoui R, Rejon C, Chatterjee S, Szymborski J, Meterissian S, Muller W, et al. Progressive polarity loss and luminal collapse disrupt tissue organization in carcinoma. Genes Dev. 2017;31:1573-1587 pubmed publisher
Forteza R, Wald F, Mashukova A, Kozhekbaeva Z, SALAS P. Par-complex aPKC and Par3 cross-talk with innate immunity NF-κB pathway in epithelial cells. Biol Open. 2013;2:1264-9 pubmed publisher
Kikuchi K, Soundararajan A, Zarzabal L, Weems C, Nelon L, Hampton S, et al. Protein kinase C iota as a therapeutic target in alveolar rhabdomyosarcoma. Oncogene. 2013;32:286-95 pubmed publisher
product information
Cat.# :
610175
Brand :
BD Transduction Laboratories
Name :
PKC
Format :
Purified
Clone :
23/PKC
Isotype :
Ms IgG 2b
React :
Hu , Ms , Rat , Dog , Chick
Conc :
250 µg/ml
Apps :
IF , IHC , IP , WB
Size :
50 µg
Status :
RUO
List Price :
207.00 USD
more info or order :
BD Biosciences product webpage
company information