product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Catenin
catalog :
610153
quantity :
50 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
14/Beta-Catenin
reactivity :
African green monkey, Nile tilapia, human, mouse, rat, dogs, chicken, pigs , zebrafish , rhesus macaque
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section, other
more info or order :
citations: 236
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:100; loading ...; fig 5d
Tan X, Zhang L, Li T, Zhan J, Qiao K, Wu H, et al. Lgr4 Regulates Oviductal Epithelial Secretion Through the WNT Signaling Pathway. Front Cell Dev Biol. 2021;9:666303 pubmed publisher
  • immunohistochemistry; rat; loading ...; fig 1f
Chen Y, Li J, Menon R, Jayaraman A, Lee K, Huang Y, et al. Dietary spinach reshapes the gut microbiome in an Apc-mutant genetic background: mechanistic insights from integrated multi-omics. Gut Microbes. 2021;13:1972756 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 4
  • western blot; human; loading ...; fig 3d
Mygland L, Brinch S, Strand M, Olsen P, Aizenshtadt A, Lund K, et al. Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines. iScience. 2021;24:102807 pubmed publisher
  • immunoprecipitation; mouse; 1:1000; loading ...; fig 5a
Beckmann D, Römer Hillmann A, Krause A, Hansen U, Wehmeyer C, Intemann J, et al. Lasp1 regulates adherens junction dynamics and fibroblast transformation in destructive arthritis. Nat Commun. 2021;12:3624 pubmed publisher
  • immunocytochemistry; human; 1:400; loading ...; fig 4g
  • western blot; human; 1:2000; loading ...; fig 2a
Goswami S, Balasubramanian I, D Agostino L, Bandyopadhyay S, Patel R, Avasthi S, et al. RAB11A-mediated YAP localization to adherens and tight junctions is essential for colonic epithelial integrity. J Biol Chem. 2021;297:100848 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig s8-2b
Zewdu R, Mehrabad E, Ingram K, Fang P, Gillis K, Camolotto S, et al. An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma. elife. 2021;10: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 3e
Zheng F, Chen Z, Tang Q, Wang X, Chong D, Zhang T, et al. Cholesterol metabolic enzyme Ggpps regulates epicardium development and ventricular wall architecture integrity in mice. J Mol Cell Biol. 2021;13:445-454 pubmed publisher
  • immunocytochemistry; human; 1:250; loading ...; fig 4b
  • western blot; human; loading ...; fig 4a
Wijshake T, Zou Z, Chen B, Zhong L, Xiao G, Xie Y, et al. Tumor-suppressor function of Beclin 1 in breast cancer cells requires E-cadherin. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
  • immunocytochemistry; human; fig 5d
Lu M, Qin X, Zhou Y, Li G, Liu Z, Geng X, et al. Long non-coding RNA LINC00665 promotes gemcitabine resistance of Cholangiocarcinoma cells via regulating EMT and stemness properties through miR-424-5p/BCL9L axis. Cell Death Dis. 2021;12:72 pubmed publisher
  • immunohistochemistry; human; 1:100; loading ...; fig 1b
Christgen M, Bartels S, van Luttikhuizen J, Bublitz J, Rieger L, Christgen H, et al. E-cadherin to P-cadherin switching in lobular breast cancer with tubular elements. Mod Pathol. 2020;33:2483-2498 pubmed publisher
  • immunohistochemistry; mouse; 1:300; loading ...; fig 2a
Borges K, Pignatti E, Leng S, Kariyawasam D, Ruiz Babot G, Ramalho F, et al. Wnt/β-catenin activation cooperates with loss of p53 to cause adrenocortical carcinoma in mice. Oncogene. 2020;39:5282-5291 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 1a
Waaler J, Mygland L, Tveita A, Strand M, Solberg N, Olsen P, et al. Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models. Commun Biol. 2020;3:196 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2b
Zhang S, Kim B, Zhu X, Gui X, Wang Y, Lan Z, et al. Glial type specific regulation of CNS angiogenesis by HIFα-activated different signaling pathways. Nat Commun. 2020;11:2027 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 3i
Eom T, Han S, Kim J, Blundon J, Wang Y, Yu J, et al. Schizophrenia-related microdeletion causes defective ciliary motility and brain ventricle enlargement via microRNA-dependent mechanisms in mice. Nat Commun. 2020;11:912 pubmed publisher
  • immunohistochemistry; mouse; 1:2000; loading ...; fig 6b
Kjell J, Fischer Sternjak J, Thompson A, Friess C, Sticco M, Salinas F, et al. Defining the Adult Neural Stem Cell Niche Proteome Identifies Key Regulators of Adult Neurogenesis. Cell Stem Cell. 2020;26:277-293.e8 pubmed publisher
  • immunocytochemistry; mouse; 1:400; loading ...; fig 4a
  • immunocytochemistry; human; 1:400; loading ...; fig 4a
Diaz Cuadros M, Wagner D, Budjan C, Hubaud A, Tarazona O, Donelly S, et al. In vitro characterization of the human segmentation clock. Nature. 2020;580:113-118 pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig 5s1a
Dos Santos Carvalho S, Moreau M, Hien Y, Garcia M, Aubailly N, Henderson D, et al. Vangl2 acts at the interface between actin and N-cadherin to modulate mammalian neuronal outgrowth. elife. 2020;9: pubmed publisher
  • immunocytochemistry; mouse; 1:5000; loading ...; fig 4c
  • western blot; mouse; loading ...; fig 4h
Pedone E, Postiglione L, Aulicino F, Rocca D, Montes Olivas S, Khazim M, et al. A tunable dual-input system for on-demand dynamic gene expression regulation. Nat Commun. 2019;10:4481 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 4b
Morris J, Yashinskie J, Koche R, Chandwani R, Tian S, Chen C, et al. α-Ketoglutarate links p53 to cell fate during tumour suppression. Nature. 2019;573:595-599 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 1v
Quilichini E, Fabre M, Dirami T, Stedman A, De Vas M, Ozguc O, et al. Pancreatic ductal deletion of Hnf1b disrupts exocrine homeostasis, leads to pancreatitis and facilitates tumorigenesis. Cell Mol Gastroenterol Hepatol. 2019;: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6a
Chaves Pérez A, Yilmaz M, Perna C, de la Rosa S, Djouder N. URI is required to maintain intestinal architecture during ionizing radiation. Science. 2019;364: pubmed publisher
  • immunohistochemistry; mouse; 1:300; loading ...; fig 3a
Storti F, Klee K, Todorova V, Steiner R, Othman A, van der Velde Visser S, et al. Impaired ABCA1/ABCG1-mediated lipid efflux in the mouse retinal pigment epithelium (RPE) leads to retinal degeneration. elife. 2019;8: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 3c
Johansson J, Nászai M, Hodder M, Pickering K, Miller B, Ridgway R, et al. RAL GTPases Drive Intestinal Stem Cell Function and Regeneration through Internalization of WNT Signalosomes. Cell Stem Cell. 2019;24:592-607.e7 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 4b
Shah A, Melhuish T, Fox T, Frierson H, Wotton D. TGIF transcription factors repress acetyl CoA metabolic gene expression and promote intestinal tumor growth. Genes Dev. 2019;33:388-402 pubmed publisher
  • western blot; human; loading ...; fig 7a
Birgisdottir A, Mouilleron S, Bhujabal Z, Wirth M, Sjøttem E, Evjen G, et al. Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy. 2019;15:1333-1355 pubmed publisher
  • immunohistochemistry; mouse; 1:2000; loading ...; fig 6j
Hoefert J, Bjerke G, Wang D, Yi R. The microRNA-200 family coordinately regulates cell adhesion and proliferation in hair morphogenesis. J Cell Biol. 2018;217:2185-2204 pubmed publisher
  • immunoprecipitation; mouse; fig 5d
  • western blot; mouse; 1:1000; fig 1a
Chen X, Wang R, Liu X, Wu Y, Zhou T, Yang Y, et al. A Chemical-Genetic Approach Reveals the Distinct Roles of GSK3? and GSK3? in Regulating Embryonic Stem Cell Fate. Dev Cell. 2017;43:563-576.e4 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 3c
Wanet A, Caruso M, Domelevo Entfellner J, Najar M, Fattaccioli A, Demazy C, et al. The Transcription Factor 7-Like 2-Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Axis Connects Mitochondrial Biogenesis and Metabolic Shift with Stem Cell Commitment to Hepatic Differentiation. Stem Cells. 2017;35:2184-2197 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 2c
  • immunohistochemistry; human; loading ...; fig s3j
Tammela T, Sanchez Rivera F, Cetinbas N, Wu K, Joshi N, Helenius K, et al. A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma. Nature. 2017;545:355-359 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 5a
Wu Y, Jhao Y, Cheng Y, Chen Y. 15-Deoxy-?12,14-prostaglandin J2 inhibits migration of human thyroid carcinoma cells by disrupting focal adhesion complex and adherens junction. Oncol Lett. 2017;13:2569-2576 pubmed publisher
  • immunocytochemistry; mouse; fig 6e
  • immunocytochemistry; chicken; fig 5e
Li Y, Urban A, Midura D, Simon H, Wang Q. Proteomic characterization of epicardial-myocardial signaling reveals novel regulatory networks including a role for NF-κB in epicardial EMT. PLoS ONE. 2017;12:e0174563 pubmed publisher
  • immunohistochemistry; human; 1:100; loading ...; fig 3e
Ojeh N, Akgul B, Tomic Canic M, Philpott M, Navsaria H. In vitro skin models to study epithelial regeneration from the hair follicle. PLoS ONE. 2017;12:e0174389 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig s4a
Fumagalli A, Drost J, Suijkerbuijk S, van Boxtel R, de Ligt J, Offerhaus G, et al. Genetic dissection of colorectal cancer progression by orthotopic transplantation of engineered cancer organoids. Proc Natl Acad Sci U S A. 2017;114:E2357-E2364 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 5a
  • western blot; human; 1:1000; loading ...; fig 6c
  • western blot; mouse; 1:1000; fig 4e
Subramaniam M, Cicek M, Pitel K, Bruinsma E, Nelson Holte M, Withers S, et al. TIEG1 modulates ?-catenin sub-cellular localization and enhances Wnt signaling in bone. Nucleic Acids Res. 2017;45:5170-5182 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig st2
Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol. 2017;30:79-107 pubmed publisher
  • western blot; mouse; 1:200; fig s7a
Kechele D, Blue R, Zwarycz B, Espenschied S, Mah A, Siegel M, et al. Orphan Gpr182 suppresses ERK-mediated intestinal proliferation during regeneration and adenoma formation. J Clin Invest. 2017;127:593-607 pubmed publisher
  • immunohistochemistry - paraffin section; dogs; 0.8 ug/ml; fig 4m
Yokoyama N, Ohta H, Kagawa Y, Leela Arporn R, Dermlim A, Nisa K, et al. Expression of apical junction complex proteins in colorectal mucosa of miniature dachshunds with inflammatory colorectal polyps. J Vet Med Sci. 2017;79:456-463 pubmed publisher
  • western blot; human; 1:5000; fig 1f
Bruurs L, Zwakenberg S, van der Net M, Zwartkruis F, Bos J. A Two-Tiered Mechanism Enables Localized Cdc42 Signaling during Enterocyte Polarization. Mol Cell Biol. 2017;37: pubmed publisher
  • western blot; human; fig 5b
van Andel H, Ren Z, Koopmans I, Joosten S, Kocemba K, de Lau W, et al. Aberrantly expressed LGR4 empowers Wnt signaling in multiple myeloma by hijacking osteoblast-derived R-spondins. Proc Natl Acad Sci U S A. 2017;114:376-381 pubmed publisher
  • immunocytochemistry; human; loading ...; fig e5b
  • immunohistochemistry - paraffin section; mouse; loading ...; fig e5h
Harper K, Sosa M, Entenberg D, Hosseini H, Cheung J, Nobre R, et al. Mechanism of early dissemination and metastasis in Her2+ mammary cancer. Nature. 2016;540:588-592 pubmed publisher
  • western blot; human; fig 5
Kumazoe M, Takai M, Bae J, Hiroi S, Huang Y, Takamatsu K, et al. FOXO3 is essential for CD44 expression in pancreatic cancer cells. Oncogene. 2017;36:2643-2654 pubmed publisher
  • western blot; mouse; loading ...; fig 1a
Kim W, Khan S, Gvozdenovic Jeremic J, Kim Y, Dahlman J, Kim H, et al. Hippo signaling interactions with Wnt/?-catenin and Notch signaling repress liver tumorigenesis. J Clin Invest. 2017;127:137-152 pubmed publisher
  • immunocytochemistry; mouse; 1:100; loading ...; fig s8b
  • immunohistochemistry; mouse; 1:100; loading ...; fig 7a
Lian G, Dettenhofer M, Lu J, Downing M, Chenn A, Wong T, et al. Filamin A- and formin 2-dependent endocytosis regulates proliferation via the canonical Wnt pathway. Development. 2016;143:4509-4520 pubmed
  • western blot; mouse; 1:1000; loading ...; fig 7a
Powis R, Karyka E, Boyd P, Côme J, Jones R, Zheng Y, et al. Systemic restoration of UBA1 ameliorates disease in spinal muscular atrophy. JCI Insight. 2016;1:e87908 pubmed publisher
  • immunocytochemistry; human; 2.5 ug/ml; loading ...; fig 4e
Matos M, Lapyckyj L, Rosso M, Besso M, Mencucci M, Briggiler C, et al. Identification of a Novel Human E-Cadherin Splice Variant and Assessment of Its Effects Upon EMT-Related Events. J Cell Physiol. 2017;232:1368-1386 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3b
Kikuchi I, Takahashi Kanemitsu A, Sakiyama N, Tang C, Tang P, Noda S, et al. Dephosphorylated parafibromin is a transcriptional coactivator of the Wnt/Hedgehog/Notch pathways. Nat Commun. 2016;7:12887 pubmed publisher
  • western blot; human; 1:1000; fig 2c
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 1b
  • western blot; mouse; 1:1000; loading ...; fig 2d
  • western blot; African green monkey; 1:1000; loading ...; fig 2c
Drelon C, Berthon A, Sahut Barnola I, Mathieu M, Dumontet T, Rodriguez S, et al. PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development. Nat Commun. 2016;7:12751 pubmed publisher
  • western blot; human; 1:1000; fig 3
Sousa A, Rei M, Freitas R, Ricardo S, Caffrey T, David L, et al. Effect of MUC1/?-catenin interaction on the tumorigenic capacity of pancreatic CD133+ cells. Oncol Lett. 2016;12:1811-1817 pubmed
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 6
Perdigoto C, Dauber K, Bar C, Tsai P, Valdes V, Cohen I, et al. Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development. PLoS Genet. 2016;12:e1006151 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:1000; tbl 3
Frohwitter G, Buerger H, van Diest P, Korsching E, Kleinheinz J, Fillies T. Cytokeratin and protein expression patterns in squamous cell carcinoma of the oral cavity provide evidence for two distinct pathogenetic pathways. Oncol Lett. 2016;12:107-113 pubmed
  • western blot; mouse; fig 2
Fagnocchi L, Cherubini A, Hatsuda H, Fasciani A, Mazzoleni S, Poli V, et al. A Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identity. Nat Commun. 2016;7:11903 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:150; fig 4
  • western blot; mouse
Hey F, Giblett S, Forrest S, Herbert C, Pritchard C. Phosphorylations of Serines 21/9 in Glycogen Synthase Kinase 3α/β Are Not Required for Cell Lineage Commitment or WNT Signaling in the Normal Mouse Intestine. PLoS ONE. 2016;11:e0156877 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 3c
Parang B, Bradley A, Mittal M, Short S, Thompson J, Barrett C, et al. Myeloid translocation genes differentially regulate colorectal cancer programs. Oncogene. 2016;35:6341-6349 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:250; fig 7
De Cian M, Pauper E, Bandiera R, Vidal V, Sacco S, Gregoire E, et al. Amplification of R-spondin1 signaling induces granulosa cell fate defects and cancers in mouse adult ovary. Oncogene. 2017;36:208-218 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 1
Park J, Kotani T, Konno T, Setiawan J, Kitamura Y, Imada S, et al. Promotion of Intestinal Epithelial Cell Turnover by Commensal Bacteria: Role of Short-Chain Fatty Acids. PLoS ONE. 2016;11:e0156334 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 4e
Jacobsen A, Heijmans N, Verkaar F, Smit M, Heringa J, van Amerongen R, et al. Construction and Experimental Validation of a Petri Net Model of Wnt/β-Catenin Signaling. PLoS ONE. 2016;11:e0155743 pubmed publisher
  • western blot; mouse; fig 6
Zeng L, Cai C, Li S, Wang W, Li Y, Chen J, et al. Essential Roles of Cyclin Y-Like 1 and Cyclin Y in Dividing Wnt-Responsive Mammary Stem/Progenitor Cells. PLoS Genet. 2016;12:e1006055 pubmed publisher
  • immunocytochemistry; pigs ; fig 1
  • western blot; pigs ; 1:1000; fig 1
  • immunocytochemistry; human; fig 1
  • western blot; human; 1:1000; fig 1
Inada M, Izawa G, Kobayashi W, Ozawa M. 293 cells express both epithelial as well as mesenchymal cell adhesion molecules. Int J Mol Med. 2016;37:1521-7 pubmed publisher
  • immunocytochemistry; human; 1:400; loading ...; fig s7b
  • immunohistochemistry - paraffin section; mouse; fig s4a
Oudhoff M, Braam M, Freeman S, Wong D, Rattray D, Wang J, et al. SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/?-Catenin and Hippo/YAP Signaling. Dev Cell. 2016;37:47-57 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 4e
Holloway K, Sinha V, Bu W, Toneff M, Dong J, Peng Y, et al. Targeting Oncogenes into a Defined Subset of Mammary Cells Demonstrates That the Initiating Oncogenic Mutation Defines the Resulting Tumor Phenotype. Int J Biol Sci. 2016;12:381-8 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:800; fig 2
Kim H, Kim J, Nam K, Kim W. Clinical significance of midkine expression in sporadic desmoid tumors. Oncol Lett. 2016;11:1677-1684 pubmed
  • immunohistochemistry - paraffin section; human; 1:500; fig s1
Koussounadis A, Langdon S, Um I, Kay C, Francis K, Harrison D, et al. Dynamic modulation of phosphoprotein expression in ovarian cancer xenograft models. BMC Cancer. 2016;16:205 pubmed publisher
  • western blot; human; 1:10,000; fig s1
Clifford R, Maryon E, Kaplan J. Dynamic internalization and recycling of a metal ion transporter: Cu homeostasis and CTR1, the human Cu⁺ uptake system. J Cell Sci. 2016;129:1711-21 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 7
Kabat A, Harrison O, Riffelmacher T, Moghaddam A, Pearson C, Laing A, et al. The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation. elife. 2016;5:e12444 pubmed publisher
  • immunocytochemistry; human; 1:500; fig 2
  • western blot; human; 1:2500; fig 2
Weyemi U, Redon C, Choudhuri R, Aziz T, Maeda D, Boufraqech M, et al. The histone variant H2A.X is a regulator of the epithelial-mesenchymal transition. Nat Commun. 2016;7:10711 pubmed publisher
  • immunohistochemistry; mouse; 1:400; fig 2
  • western blot; mouse; fig 4
Zhang Y, Fan J, Ho J, Hu T, Kneeland S, Fan X, et al. Crim1 regulates integrin signaling in murine lens development. Development. 2016;143:356-66 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
Ye S, Zhang D, Cheng F, Wilson D, Mackay J, He K, et al. Wnt/β-catenin and LIF-Stat3 signaling pathways converge on Sp5 to promote mouse embryonic stem cell self-renewal. J Cell Sci. 2016;129:269-76 pubmed publisher
  • immunocytochemistry; mouse; 1:200; fig 6
Bizet A, Becker Heck A, Ryan R, Weber K, Filhol E, Krug P, et al. Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization. Nat Commun. 2015;6:8666 pubmed publisher
  • immunohistochemistry; mouse
Arya P, Rainey M, Bhattacharyya S, Mohapatra B, George M, Kuracha M, et al. The endocytic recycling regulatory protein EHD1 Is required for ocular lens development. Dev Biol. 2015;408:41-55 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig st1
Hwang J, Sung W, Tu H, Hsieh K, Yeh C, Chen C, et al. The Overexpression of FEN1 and RAD54B May Act as Independent Prognostic Factors of Lung Adenocarcinoma. PLoS ONE. 2015;10:e0139435 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; fig s4
Nemazanyy I, Montagnac G, Russell R, Morzyglod L, Burnol A, Guan K, et al. Class III PI3K regulates organismal glucose homeostasis by providing negative feedback on hepatic insulin signalling. Nat Commun. 2015;6:8283 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 6a
Basak P, Dillon R, Leslie H, Raouf A, Mowat M. The Deleted in Liver Cancer 1 (Dlc1) tumor suppressor is haploinsufficient for mammary gland development and epithelial cell polarity. BMC Cancer. 2015;15:630 pubmed publisher
  • western blot; human
Sivaraj K, Li R, Albarrán Juárez J, Wang S, Tischner D, Grimm M, et al. Endothelial Gαq/11 is required for VEGF-induced vascular permeability and angiogenesis. Cardiovasc Res. 2015;108:171-80 pubmed publisher
  • immunohistochemistry; mouse
Ohata S, Herranz Pérez V, Nakatani J, Boletta A, García Verdugo J, Álvarez Buylla A. Mechanosensory Genes Pkd1 and Pkd2 Contribute to the Planar Polarization of Brain Ventricular Epithelium. J Neurosci. 2015;35:11153-68 pubmed publisher
  • immunocytochemistry; human; fig 7
  • western blot; human; fig 6
Yang G, Xu Z, Lu W, Li X, Sun C, Guo J, et al. Quantitative Analysis of Differential Proteome Expression in Bladder Cancer vs. Normal Bladder Cells Using SILAC Method. PLoS ONE. 2015;10:e0134727 pubmed publisher
  • western blot; mouse; fig 6
Hamazaki J, Hirayama S, Murata S. Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis. PLoS Genet. 2015;11:e1005401 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1a
Piccolo E, Tinari N, D Addario D, Rossi C, Iacobelli V, La Sorda R, et al. Prognostic relevance of LGALS3BP in human colorectal carcinoma. J Transl Med. 2015;13:248 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; tbl 2
Takahashi S, Kohashi K, Yamamoto H, Hirahashi M, Kumagai R, Takizawa N, et al. Expression of adhesion molecules and epithelial-mesenchymal transition factors in medullary carcinoma of the colorectum. Hum Pathol. 2015;46:1257-66 pubmed publisher
  • western blot; human; 1:400; fig 3
Kontro H, Cannino G, Rustin P, Dufour E, Kainulainen H. DAPIT Over-Expression Modulates Glucose Metabolism and Cell Behaviour in HEK293T Cells. PLoS ONE. 2015;10:e0131990 pubmed publisher
  • western blot; human; fig 4
Grikscheit K, Frank T, Wang Y, Grosse R. Junctional actin assembly is mediated by Formin-like 2 downstream of Rac1. J Cell Biol. 2015;209:367-76 pubmed publisher
  • immunocytochemistry; rat
Overgaard C, Schlingmann B, Dorsainvil White S, Ward C, Fan X, Swarnakar S, et al. The relative balance of GM-CSF and TGF-β1 regulates lung epithelial barrier function. Am J Physiol Lung Cell Mol Physiol. 2015;308:L1212-23 pubmed publisher
  • immunohistochemistry - paraffin section; Nile tilapia
Hsiao C, Wu Y, Nan F, Huang S, Chen L, Chen S. Immunomodulator 'mushroom beta glucan' induces Wnt/β catenin signalling and improves wound recovery in tilapia and rat skin: a histopathological study. Int Wound J. 2016;13:1116-1128 pubmed publisher
  • immunocytochemistry; human; 1:150; fig 2
Kubelt C, Hattermann K, Sebens S, Mehdorn H, Held Feindt J. Epithelial-to-mesenchymal transition in paired human primary and recurrent glioblastomas. Int J Oncol. 2015;46:2515-25 pubmed publisher
  • western blot; human
Tsukiyama T, Fukui A, Terai S, Fujioka Y, Shinada K, Takahashi H, et al. Molecular Role of RNF43 in Canonical and Noncanonical Wnt Signaling. Mol Cell Biol. 2015;35:2007-23 pubmed publisher
  • immunohistochemistry; human; fig 3
Bazellières E, Conte V, Elosegui Artola A, Serra Picamal X, Bintanel Morcillo M, Roca Cusachs P, et al. Control of cell-cell forces and collective cell dynamics by the intercellular adhesome. Nat Cell Biol. 2015;17:409-20 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:20; fig 8
  • western blot; mouse; 1:1000; fig 8
Iervolino A, Trepiccione F, Petrillo F, Spagnuolo M, Scarfò M, Frezzetti D, et al. Selective dicer suppression in the kidney alters GSK3β/β-catenin pathways promoting a glomerulocystic disease. PLoS ONE. 2015;10:e0119142 pubmed publisher
  • immunohistochemistry; human; 1:100
Geels Y, van der Putten L, van Tilborg A, Lurkin I, Zwarthoff E, Pijnenborg J, et al. Immunohistochemical and genetic profiles of endometrioid endometrial carcinoma arising from atrophic endometrium. Gynecol Oncol. 2015;137:245-51 pubmed publisher
  • chromatin immunoprecipitation; human; fig s6
Walker M, Stopford C, Cederlund M, Fang F, Jahn C, Rabinowitz A, et al. FOXP1 potentiates Wnt/β-catenin signaling in diffuse large B cell lymphoma. Sci Signal. 2015;8:ra12 pubmed publisher
  • western blot; mouse
Cai K, Wang Y, Smith E, Smedberg J, Yang D, Yang W, et al. Global deletion of Trp53 reverts ovarian tumor phenotype of the germ cell-deficient white spotting variant (Wv) mice. Neoplasia. 2015;17:89-100 pubmed publisher
  • other; human; loading ...; fig 3a
  • immunoprecipitation; human; loading ...; fig 7b
  • western blot; human; loading ...; fig 4a
Traenkle B, Emele F, Anton R, Poetz O, Haeussler R, Maier J, et al. Monitoring interactions and dynamics of endogenous beta-catenin with intracellular nanobodies in living cells. Mol Cell Proteomics. 2015;14:707-23 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 4
López Escobar B, Cano D, Rojas A, De Felipe B, Palma F, Sánchez Alcázar J, et al. The effect of maternal diabetes on the Wnt-PCP pathway during embryogenesis as reflected in the developing mouse eye. Dis Model Mech. 2015;8:157-68 pubmed publisher
  • immunocytochemistry; human; 1:2000
  • western blot; human; 1:2000
Olsen P, Solberg N, Lund K, Vehus T, Gelazauskaite M, Wilson S, et al. Implications of targeted genomic disruption of β-catenin in BxPC-3 pancreatic adenocarcinoma cells. PLoS ONE. 2014;9:e115496 pubmed publisher
  • western blot; human; 1:500; fig s2d
Yokoi N, Fukata Y, Kase D, Miyazaki T, Jaegle M, Ohkawa T, et al. Chemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial epilepsy. Nat Med. 2015;21:19-26 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200
  • chromatin immunoprecipitation; human
Isobe T, Hisamori S, Hogan D, Zabala M, Hendrickson D, Dalerba P, et al. miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway. elife. 2014;3: pubmed publisher
  • western blot; rat; 1:800
Pérez Alvarez M, Mateos L, Alonso A, Wandosell F. Estradiol and Progesterone Administration After pMCAO Stimulates the Neurological Recovery and Reduces the Detrimental Effect of Ischemia Mainly in Hippocampus. Mol Neurobiol. 2015;52:1690-1703 pubmed publisher
  • western blot; human; 1:1000
Li F, Song N, Tombran Tink J, Niyibizi C. Pigment epithelium derived factor suppresses expression of Sost/Sclerostin by osteocytes: implication for its role in bone matrix mineralization. J Cell Physiol. 2015;230:1243-9 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Raap M, Antonopoulos W, Dämmrich M, Christgen H, Steinmann D, Länger F, et al. High frequency of lobular breast cancer in distant metastases to the orbit. Cancer Med. 2015;4:104-11 pubmed publisher
  • immunohistochemistry; mouse; 1:200
de Andrade G, Kunzelman L, Merrill M, Fuerst P. Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina. Mol Vis. 2014;20:1422-33 pubmed
  • western blot; human; loading ...; fig 3c
Kim H, Park J, Won H, Lee J, Kong G. CBX7 inhibits breast tumorigenicity through DKK-1-mediated suppression of the Wnt/β-catenin pathway. FASEB J. 2015;29:300-13 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 5a
Jansen S, Holman R, Hedemann I, Frankes E, Elzinga C, Timens W, et al. Prostaglandin E2 promotes MYCN non-amplified neuroblastoma cell survival via β-catenin stabilization. J Cell Mol Med. 2015;19:210-26 pubmed publisher
  • immunohistochemistry - paraffin section; human
O Shea C, Fitzpatrick J, Koch P. Desmosomal defects in acantholytic squamous cell carcinomas. J Cutan Pathol. 2014;41:873-9 pubmed publisher
  • western blot; human; 1:500
Fan C, Jiang G, Zhang X, Miao Y, Lin X, Luan L, et al. Zbed3 contributes to malignant phenotype of lung cancer via regulating β-catenin and P120-catenin 1. Mol Carcinog. 2015;54 Suppl 1:E138-47 pubmed publisher
  • western blot; human
Jia D, Yang W, Li L, Liu H, Tan Y, Ooi S, et al. β-Catenin and NF-κB co-activation triggered by TLR3 stimulation facilitates stem cell-like phenotypes in breast cancer. Cell Death Differ. 2015;22:298-310 pubmed publisher
  • immunocytochemistry; human
Rubashkin M, Cassereau L, Bainer R, DuFort C, Yui Y, Ou G, et al. Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate. Cancer Res. 2014;74:4597-611 pubmed publisher
  • immunohistochemistry; human; 1:2500; fig s3
Van Brocklyn J, Wojton J, Meisen W, Kellough D, Ecsedy J, Kaur B, et al. Aurora-A inhibition offers a novel therapy effective against intracranial glioblastoma. Cancer Res. 2014;74:5364-70 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 3
Wanet A, Remacle N, Najar M, Sokal E, Arnould T, Najimi M, et al. Mitochondrial remodeling in hepatic differentiation and dedifferentiation. Int J Biochem Cell Biol. 2014;54:174-85 pubmed publisher
  • immunocytochemistry; human
Crespi A, Bertoni A, Ferrari I, Padovano V, Della Mina P, Berti E, et al. POF1B localizes to desmosomes and regulates cell adhesion in human intestinal and keratinocyte cell lines. J Invest Dermatol. 2015;135:192-201 pubmed publisher
  • western blot; dogs; fig 1
Ohta H, Sunden Y, Yokoyama N, Osuga T, Lim S, Tamura Y, et al. Expression of apical junction complex proteins in duodenal mucosa of dogs with inflammatory bowel disease. Am J Vet Res. 2014;75:746-51 pubmed publisher
  • western blot; human
Ohkawa T, Satake S, Yokoi N, Miyazaki Y, Ohshita T, Sobue G, et al. Identification and characterization of GABA(A) receptor autoantibodies in autoimmune encephalitis. J Neurosci. 2014;34:8151-63 pubmed publisher
  • western blot; human
Zhu Z, Liu Y, Li K, Liu J, Wang H, Sun B, et al. Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility. Carcinogenesis. 2014;35:1901-10 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Godde N, Sheridan J, Smith L, Pearson H, Britt K, Galea R, et al. Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland. PLoS Genet. 2014;10:e1004323 pubmed publisher
  • immunoprecipitation; mouse
  • immunohistochemistry; mouse
  • western blot; mouse
Durak O, de Anda F, Singh K, Leussis M, Petryshen T, Sklar P, et al. Ankyrin-G regulates neurogenesis and Wnt signaling by altering the subcellular localization of ?-catenin. Mol Psychiatry. 2015;20:388-97 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500
  • western blot; mouse; 1:500
Hatakeyama J, Wakamatsu Y, Nagafuchi A, Kageyama R, Shigemoto R, Shimamura K. Cadherin-based adhesions in the apical endfoot are required for active Notch signaling to control neurogenesis in vertebrates. Development. 2014;141:1671-82 pubmed publisher
  • immunohistochemistry - free floating section; rhesus macaque; 1:500
Alfaro Cervello C, Cebrian Silla A, Soriano Navarro M, García Tárraga P, Matías Guiu J, Gomez Pinedo U, et al. The adult macaque spinal cord central canal zone contains proliferative cells and closely resembles the human. J Comp Neurol. 2014;522:1800-17 pubmed publisher
  • immunohistochemistry - paraffin section; human
Ramaiahgari S, den Braver M, Herpers B, Terpstra V, Commandeur J, van de Water B, et al. A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies. Arch Toxicol. 2014;88:1083-95 pubmed publisher
  • immunohistochemistry - paraffin section; human
Boin A, Couvelard A, Couderc C, Brito I, Filipescu D, Kalamarides M, et al. Proteomic screening identifies a YAP-driven signaling network linked to tumor cell proliferation in human schwannomas. Neuro Oncol. 2014;16:1196-209 pubmed publisher
  • immunocytochemistry; mouse
Martianov I, Cler E, Duluc I, Vicaire S, Philipps M, Freund J, et al. TAF4 inactivation reveals the 3 dimensional growth promoting activities of collagen 6A3. PLoS ONE. 2014;9:e87365 pubmed publisher
  • western blot; human
Kriz V, Pospichalova V, Masek J, Kilander M, Slavík J, Tanneberger K, et al. ?-arrestin promotes Wnt-induced low density lipoprotein receptor-related protein 6 (Lrp6) phosphorylation via increased membrane recruitment of Amer1 protein. J Biol Chem. 2014;289:1128-41 pubmed publisher
  • immunohistochemistry; rat
Dawes L, Sugiyama Y, Lovicu F, Harris C, Shelley E, McAvoy J. Interactions between lens epithelial and fiber cells reveal an intrinsic self-assembly mechanism. Dev Biol. 2014;385:291-303 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:8000; fig 3
Müller M, Florian S, Pommer S, Osterhoff M, Esworthy R, Chu F, et al. Deletion of glutathione peroxidase-2 inhibits azoxymethane-induced colon cancer development. PLoS ONE. 2013;8:e72055 pubmed publisher
  • chromatin immunoprecipitation; mouse
  • western blot; mouse
Lu H, Hu L, Yu L, Wang X, Urvalek A, Li T, et al. KLF8 and FAK cooperatively enrich the active MMP14 on the cell surface required for the metastatic progression of breast cancer. Oncogene. 2014;33:2909-17 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500
King S, Mohiuddin J, Dekaney C. Paneth cells expand from newly created and preexisting cells during repair after doxorubicin-induced damage. Am J Physiol Gastrointest Liver Physiol. 2013;305:G151-62 pubmed publisher
  • immunoprecipitation; human; 2 ug/time
  • western blot; human; 1:2000; fig 7a
Li Y, Zheng Y, Izumi K, Ishiguro H, Ye B, Li F, et al. Androgen activates ?-catenin signaling in bladder cancer cells. Endocr Relat Cancer. 2013;20:293-304 pubmed publisher
  • immunohistochemistry; mouse; 1:200
  • western blot; mouse; 1:1000
Lang J, Maeda Y, Bannerman P, Xu J, Horiuchi M, Pleasure D, et al. Adenomatous polyposis coli regulates oligodendroglial development. J Neurosci. 2013;33:3113-30 pubmed publisher
  • western blot; rat
Dawes L, Sugiyama Y, Tanedo A, Lovicu F, McAvoy J. Wnt-frizzled signaling is part of an FGF-induced cascade that promotes lens fiber differentiation. Invest Ophthalmol Vis Sci. 2013;54:1582-90 pubmed publisher
  • western blot; human; fig 1
  • immunohistochemistry; mouse
  • western blot; mouse
Han J, Soletti R, Sadarangani A, Sridevi P, Ramirez M, Eckmann L, et al. Nuclear expression of ?-catenin promotes RB stability and resistance to TNF-induced apoptosis in colon cancer cells. Mol Cancer Res. 2013;11:207-18 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100
Nakanishi Y, Seno H, Fukuoka A, Ueo T, Yamaga Y, Maruno T, et al. Dclk1 distinguishes between tumor and normal stem cells in the intestine. Nat Genet. 2013;45:98-103 pubmed publisher
  • immunocytochemistry; human; 1:500; fig 3
McClain C, Sim F, Goldman S. Pleiotrophin suppression of receptor protein tyrosine phosphatase-?/? maintains the self-renewal competence of fetal human oligodendrocyte progenitor cells. J Neurosci. 2012;32:15066-75 pubmed publisher
  • western blot; mouse
Curtis C, Griffin C. The chromatin-remodeling enzymes BRG1 and CHD4 antagonistically regulate vascular Wnt signaling. Mol Cell Biol. 2012;32:1312-20 pubmed publisher
  • immunohistochemistry; mouse; 0.8 ug/ml; loading ...; fig 2i
  • western blot; dogs; 0.08 ug/ml; loading ...; fig 1
Ohta H, Yamaguchi T, Rajapakshage B, Murakami M, Sasaki N, Nakamura K, et al. Expression and subcellular localization of apical junction proteins in canine duodenal and colonic mucosa. Am J Vet Res. 2011;72:1046-51 pubmed publisher
  • western blot; mouse; 1:2000; fig 6a
Gladden A, Hebert A, Schneeberger E, McClatchey A. The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex. Dev Cell. 2010;19:727-39 pubmed publisher
  • western blot; human; fig 3
Revet I, Huizenga G, Koster J, Volckmann R, van Sluis P, Versteeg R, et al. MSX1 induces the Wnt pathway antagonist genes DKK1, DKK2, DKK3, and SFRP1 in neuroblastoma cells, but does not block Wnt3 and Wnt5A signalling to DVL3. Cancer Lett. 2010;289:195-207 pubmed publisher
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Kurek D, Garinis G, van Doorninck J, van der Wees J, Grosveld F. Transcriptome and phenotypic analysis reveals Gata3-dependent signalling pathways in murine hair follicles. Development. 2007;134:261-72 pubmed
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Sayedyahossein S, Huang K, Li Z, Zhang C, Kozlov A, Johnston D, et al. Pannexin 1 binds β-catenin to modulate melanoma cell growth and metabolism. J Biol Chem. 2021;296:100478 pubmed publisher
Morenilla Palao C, López Cascales M, Lopez Atalaya J, Baeza D, Calvo Díaz L, Barco A, et al. A Zic2-regulated switch in a noncanonical Wnt/βcatenin pathway is essential for the formation of bilateral circuits. Sci Adv. 2020;6: pubmed publisher
Li T, Ren J, Husmann D, Coan J, Gozani O, Chua K. Multivalent tumor suppressor adenomatous polyposis coli promotes Axin biomolecular condensate formation and efficient β-catenin degradation. Sci Rep. 2020;10:17425 pubmed publisher
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product information
Cat.# :
610153
Brand :
BD Transduction Laboratories
Name :
Catenin
Format :
Purified
Clone :
14/Beta-Catenin
Isotype :
Ms IgG 1
React :
Hu , Ms , Rat , Dog , Chick
Conc :
250 µg/ml
Apps :
IF , IHC , IP , WB
Size :
50 µg
Status :
RUO
more info or order :
company information