product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
c-Raf-1
catalog :
610151
quantity :
50 µg
price :
207.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
53/c-Raf-1
reactivity :
human, mouse, rat, dog, chicken, baker's yeast
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • immunoprecipitation; human; loading ...; fig 6b
  • western blot; human; loading ...; fig 6b
Spencer Smith R, Koide A, Zhou Y, Eguchi R, Sha F, Gajwani P, et al. Inhibition of RAS function through targeting an allosteric regulatory site. Nat Chem Biol. 2017;13:62-68 pubmed publisher
  • immunoprecipitation; human; loading ...; fig 1l
  • western blot; human; 1:5000; loading ...; fig 1a
  • immunoprecipitation; baker's yeast; fig 2b
  • western blot; baker's yeast; 1:5000; loading ...; fig 1h
Mitra S, Ghosh B, Gayen N, Roy J, Mandal A. Bipartite Role of Heat Shock Protein 90 (Hsp90) Keeps CRAF Kinase Poised for Activation. J Biol Chem. 2016;291:24579-24593 pubmed
  • immunoprecipitation; human; tbl 3
  • western blot; human; 1:1000; tbl 2
Bhargava A, Pelech S, Woodard B, Kerwin J, Maherali N. Registered report: RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth. elife. 2016;5: pubmed publisher
  • western blot; human
  • western blot; dog
Linch M, Sanz Garcia M, Rosse C, Riou P, Peel N, Madsen C, et al. Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids. Carcinogenesis. 2014;35:396-406 pubmed publisher
Nieto P, Ambrogio C, Esteban Burgos L, Gomez Lopez G, Blasco M, Yao Z, et al. A Braf kinase-inactive mutant induces lung adenocarcinoma. Nature. 2017;548:239-243 pubmed publisher
Rose J, Huang P, Camp N, Ye J, Leidal A, Goreshnik I, et al. A computationally engineered RAS rheostat reveals RAS-ERK signaling dynamics. Nat Chem Biol. 2017;13:119-126 pubmed publisher
Margineantu D, Emerson C, Diaz D, Hockenbery D. Hsp90 inhibition decreases mitochondrial protein turnover. PLoS ONE. 2007;2:e1066 pubmed
Rodríguez Muñoz M, de la Torre Madrid E, Sánchez Blázquez P, Garzón J. Morphine induces endocytosis of neuronal mu-opioid receptors through the sustained transfer of Galpha subunits to RGSZ2 proteins. Mol Pain. 2007;3:19 pubmed
product information
Cat.# :
610151
Brand :
BD Transduction Laboratories
Name :
c-Raf-1
Format :
Purified
Clone :
53/c-Raf-1
Isotype :
Ms IgG 1
React :
Hu , Ms , Rat , Dog , Chick
Conc :
250 µg/ml
Apps :
IF , IP , WB
Size :
50 µg
Status :
RUO
List Price :
207.00 USD
more info or order :
company information