product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
pp120
catalog :
610134
quantity :
150 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
98/pp120
reactivity :
human, mouse, rat, dogs, chicken
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, other
more info or order :
citations: 22
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; 1:100; loading ...; fig 4b
  • western blot; mouse; 1:1000; loading ...; fig 5a
Beckmann D, Römer Hillmann A, Krause A, Hansen U, Wehmeyer C, Intemann J, et al. Lasp1 regulates adherens junction dynamics and fibroblast transformation in destructive arthritis. Nat Commun. 2021;12:3624 pubmed publisher
  • immunohistochemistry; rat; 1:250; loading ...; fig 2d
Boon N, Alves C, Mulder A, Andriessen C, Buck T, Quinn P, et al. Defining Phenotype, Tropism, and Retinal Gene Therapy Using Adeno-Associated Viral Vectors (AAVs) in New-Born Brown Norway Rats with a Spontaneous Mutation in Crb1. Int J Mol Sci. 2021;22: pubmed publisher
  • immunohistochemistry - frozen section; human; 1:2000; loading ...; fig 6b
  • western blot; human; 1:2000; loading ...; fig 6g
  • immunoprecipitation; dogs; 1:2000; loading ...; fig 1c
  • immunocytochemistry; dogs; 1:2000; loading ...; fig 2d
  • western blot; dogs; 1:2000; loading ...; fig 1c
Wu Q, Li G, Wen C, Zeng T, Fan Y, Liu C, et al. Monoubiquitination of p120-catenin is essential for TGFβ-induced epithelial-mesenchymal transition and tumor metastasis. Sci Adv. 2020;6:eaay9819 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 1a
  • immunocytochemistry; human; 1:500; loading ...; fig 1d
van de Ven R, de Groot J, Park D, van Domselaar R, de Jong D, Szuhai K, et al. p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis. Nat Commun. 2016;7:13874 pubmed publisher
  • other; human; loading ...; fig 3
Su W, Kowalczyk A. The VE-cadherin cytoplasmic domain undergoes proteolytic processing during endocytosis. Mol Biol Cell. 2017;28:76-84 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:1000
Figueira A, Gomes C, Vilhena H, Miranda S, Carvalheira J, de Matos A, et al. Characterization of α-, β- and p120-Catenin Expression in Feline Mammary Tissues and their Relation with E- and P-Cadherin. Anticancer Res. 2015;35:3361-9 pubmed
  • immunocytochemistry; human; 1:250
  • western blot; human; 1:1000
Vitiello E, Ferreira J, Maiato H, Balda M, Matter K. The tumour suppressor DLC2 ensures mitotic fidelity by coordinating spindle positioning and cell-cell adhesion. Nat Commun. 2014;5:5826 pubmed publisher
  • western blot; human; 1:1000; fig 3
Sehgal L, Mukhopadhyay A, Rajan A, Khapare N, Sawant M, Vishal S, et al. 14-3-3?-Mediated transport of plakoglobin to the cell border is required for the initiation of desmosome assembly in vitro and in vivo. J Cell Sci. 2014;127:2174-88 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100
Akins M, Greer C. Axon behavior in the olfactory nerve reflects the involvement of catenin-cadherin mediated adhesion. J Comp Neurol. 2006;499:979-89 pubmed
Teo K, Gómez Cuadrado L, Tenhagen M, Byron A, Rätze M, van Amersfoort M, et al. E-cadherin loss induces targetable autocrine activation of growth factor signalling in lobular breast cancer. Sci Rep. 2018;8:15454 pubmed publisher
de Groot J, Ratze M, van Amersfoort M, Eisemann T, Vlug E, Niklaas M, et al. αE-catenin is a candidate tumor suppressor for the development of E-cadherin-expressing lobular-type breast cancer. J Pathol. 2018;245:456-467 pubmed publisher
Fujikake K, Sawada M, Hikita T, Seto Y, Kaneko N, Herranz Pérez V, et al. Detachment of Chain-Forming Neuroblasts by Fyn-Mediated Control of cell-cell Adhesion in the Postnatal Brain. J Neurosci. 2018;38:4598-4609 pubmed publisher
Mizoguchi T, Ikeda S, Watanabe S, Sugawara M, Itoh M. Mib1 contributes to persistent directional cell migration by regulating the Ctnnd1-Rac1 pathway. Proc Natl Acad Sci U S A. 2017;114:E9280-E9289 pubmed publisher
Lázaro Diéguez F, Müsch A. Cell-cell adhesion accounts for the different orientation of columnar and hepatocytic cell divisions. J Cell Biol. 2017;216:3847-3859 pubmed publisher
Tenhagen M, Klarenbeek S, Braumuller T, Hofmann I, van der Groep P, Ter Hoeve N, et al. p120-Catenin Is Critical for the Development of Invasive Lobular Carcinoma in Mice. J Mammary Gland Biol Neoplasia. 2016;21:81-88 pubmed
Karamchandani D, Lehman H, Ohanessian S, Massé J, Welsh P, Odze R, et al. Increasing diagnostic accuracy to grade dysplasia in Barrett's esophagus using an immunohistochemical panel for CDX2, p120ctn, c-Myc and Jagged1. Diagn Pathol. 2016;11:23 pubmed publisher
van de Ven R, Tenhagen M, Meuleman W, van Riel J, Schackmann R, Derksen P. Nuclear p120-catenin regulates the anoikis resistance of mouse lobular breast cancer cells through Kaiso-dependent Wnt11 expression. Dis Model Mech. 2015;8:373-84 pubmed publisher
Zhang Y, Zhao Y, Jiang G, Zhang X, Zhao H, Wu J, et al. Impact of p120-catenin isoforms 1A and 3A on epithelial mesenchymal transition of lung cancer cells expressing E-cadherin in different subcellular locations. PLoS ONE. 2014;9:e88064 pubmed publisher
Vermeulen J, van de Ven R, Ercan C, van der Groep P, van der Wall E, Bult P, et al. Nuclear Kaiso expression is associated with high grade and triple-negative invasive breast cancer. PLoS ONE. 2012;7:e37864 pubmed publisher
Yu J, Miao Y, Xu H, Liu Y, Jiang G, Stoecker M, et al. N-terminal 1-54 amino acid sequence and Armadillo repeat domain are indispensable for P120-catenin isoform 1A in regulating E-cadherin. PLoS ONE. 2012;7:e37008 pubmed publisher
Géraud C, Evdokimov K, Straub B, Peitsch W, Demory A, Dörflinger Y, et al. Unique cell type-specific junctional complexes in vascular endothelium of human and rat liver sinusoids. PLoS ONE. 2012;7:e34206 pubmed publisher
Kümper S, Ridley A. p120ctn and P-cadherin but not E-cadherin regulate cell motility and invasion of DU145 prostate cancer cells. PLoS ONE. 2010;5:e11801 pubmed publisher
product information
Cat.# :
610134
Brand :
BD Transduction Laboratories
Name :
pp120
Format :
Purified
Clone :
98/pp120
Isotype :
Ms IgG 1
React :
Hu , Ms , Rat , Dog , Chick
Conc :
250 µg/ml
Apps :
IF , IHC , IP , WB
Size :
150 µg
Status :
RUO
more info or order :
company information