| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry - paraffin section; mouse; loading ...; fig 2a
- immunocytochemistry; mouse; fig 1c
- western blot; mouse; fig 1a
| Eritja N, Navaridas R, Ruiz Mitjana A, Vidal Sabanés M, Egea J, Encinas M, et al. Endometrial PTEN Deficiency Leads to SMAD2/3 Nuclear Translocation. Cancers (Basel). 2021;13: pubmed publisher |
- immunocytochemistry; human; 1:300; loading ...; fig 4s1
| Butt B, Owen D, Jeffries C, Ivanova L, Hill C, Houghton J, et al. Insights into herpesvirus assembly from the structure of the pUL7:pUL51 complex. elife. 2020;9: pubmed publisher |
- immunocytochemistry; human; loading ...; fig 1a
| Taneja N, Neininger A, Burnette D. Coupling to substrate adhesions drives the maturation of muscle stress fibers into myofibrils within cardiomyocytes. Mol Biol Cell. 2020;31:1273-1288 pubmed publisher |
- immunocytochemistry; mouse; loading ...; fig s5e
| Freeman S, Uderhardt S, Saric A, Collins R, Buckley C, Mylvaganam S, et al. Lipid-gated monovalent ion fluxes regulate endocytic traffic and support immune surveillance. Science. 2020;367:301-305 pubmed publisher |
- immunocytochemistry; human; loading ...; fig s7g
| Kalappurakkal J, Anilkumar A, Patra C, van Zanten T, Sheetz M, Mayor S. Integrin Mechano-chemical Signaling Generates Plasma Membrane Nanodomains that Promote Cell Spreading. Cell. 2019;: pubmed publisher |
- immunocytochemistry; mouse; loading ...; fig s5b
| Schell C, Sabass B, Helmstaedter M, Geist F, Abed A, Yasuda Yamahara M, et al. ARP3 Controls the Podocyte Architecture at the Kidney Filtration Barrier. Dev Cell. 2018;47:741-757.e8 pubmed publisher |
- immunocytochemistry; human; fig 5c
| Chen X, Wanggou S, Bodalia A, Zhu M, Dong W, Fan J, et al. A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression. Neuron. 2018;100:799-815.e7 pubmed publisher |
- western blot; human; 1:1000; fig 2a
| Frattini V, Pagnotta S, Tala -, Fan J, Russo M, Lee S, et al. A metabolic function of FGFR3-TACC3 gene fusions in cancer. Nature. 2018;553:222-227 pubmed publisher |
- western blot; human; 1:1000; fig 3b
| Wu Y, Jhao Y, Cheng Y, Chen Y. 15-Deoxy-?12,14-prostaglandin J2 inhibits migration of human thyroid carcinoma cells by disrupting focal adhesion complex and adherens junction. Oncol Lett. 2017;13:2569-2576 pubmed publisher |
- immunocytochemistry; human; 1:100; loading ...; fig 2e
| Heim J, Squirewell E, Neu A, Zocher G, Sominidi Damodaran S, Wyles S, et al. Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix. Proc Natl Acad Sci U S A. 2017;114:3933-3938 pubmed publisher |
- immunocytochemistry; mouse; 1:300; loading ...; fig 4b
| Benito Jardón M, Klapproth S, Gimeno LLuch I, Petzold T, Bharadwaj M, Müller D, et al. The fibronectin synergy site re-enforces cell adhesion and mediates a crosstalk between integrin classes. elife. 2017;6: pubmed publisher |
- immunocytochemistry; human; loading ...; fig 3a
| Frank S, Köllmann C, van Lidth de Jeude J, Thiagarajah J, Engelholm L, Frödin M, et al. The focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion. Oncogene. 2017;36:1816-1828 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 1d
- immunocytochemistry; dogs; loading ...; fig 3e
| Taneja N, Fenix A, Rathbun L, Millis B, Tyska M, Hehnly H, et al. Focal adhesions control cleavage furrow shape and spindle tilt during mitosis. Sci Rep. 2016;6:29846 pubmed publisher |
- western blot; mouse; loading ...; fig 7a
| Hashimoto Tane A, Sakuma M, Ike H, Yokosuka T, Kimura Y, Ohara O, et al. Micro-adhesion rings surrounding TCR microclusters are essential for T cell activation. J Exp Med. 2016;213:1609-25 pubmed publisher |
- western blot; rat; 1:1000; fig s3
- immunocytochemistry; mouse; 1:200; fig 5
- western blot; mouse; 1:1000; fig 4
| Fusté N, Fernández Hernández R, Cemeli T, Mirantes C, Pedraza N, Rafel M, et al. Cytoplasmic cyclin D1 regulates cell invasion and metastasis through the phosphorylation of paxillin. Nat Commun. 2016;7:11581 pubmed publisher |
- western blot; mouse; fig 1
| Jadav R, Kumar D, Buwa N, Ganguli S, Thampatty S, Balasubramanian N, et al. Deletion of inositol hexakisphosphate kinase 1 (IP6K1) reduces cell migration and invasion, conferring protection from aerodigestive tract carcinoma in mice. Cell Signal. 2016;28:1124-36 pubmed publisher |
- western blot; human; fig 4
| Marcos Ramiro B, GarcÃa Weber D, Barroso S, Feito J, Ortega M, Cernuda Morollón E, et al. RhoB controls endothelial barrier recovery by inhibiting Rac1 trafficking to the cell border. J Cell Biol. 2016;213:385-402 pubmed publisher |
- immunohistochemistry; mouse; 1:200; loading ...; fig 2c
- western blot; mouse; 1:1000; loading ...; fig s1e
| Nader G, Ezratty E, Gundersen G. FAK, talin and PIPKI? regulate endocytosed integrin activation to polarize focal adhesion assembly. Nat Cell Biol. 2016;18:491-503 pubmed publisher |
- immunocytochemistry; zebrafish ; 1:100; fig 1
- western blot; zebrafish ; 1:1000; fig s2
| Hirth S, Bühler A, Bührdel J, Rudeck S, Dahme T, Rottbauer W, et al. Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart. PLoS ONE. 2016;11:e0150323 pubmed publisher |
- western blot; human; 1:1000; fig s5
| Kenific C, Stehbens S, Goldsmith J, Leidal A, Faure N, Ye J, et al. NBR1 enables autophagy-dependent focal adhesion turnover. J Cell Biol. 2016;212:577-90 pubmed publisher |
- immunocytochemistry; human; 1:400; fig 6
- western blot; human; 1:1000; fig 5
| Horton E, Humphries J, Stutchbury B, Jacquemet G, Ballestrem C, Barry S, et al. Modulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition. J Cell Biol. 2016;212:349-64 pubmed publisher |
- immunocytochemistry; mouse; 1:400; fig 1
- western blot; mouse; 1:1000; fig 4
| Theodosiou M, Widmaier M, Böttcher R, Rognoni E, Veelders M, Bharadwaj M, et al. Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. elife. 2016;5:e10130 pubmed publisher |
- other; human; loading ...; fig st1
| Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher |
- immunocytochemistry; human; 1:100; loading ...; fig 1a
| Calvo F, Ranftl R, Hooper S, Farrugia A, Moeendarbary E, Bruckbauer A, et al. Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts. Cell Rep. 2015;13:2699-714 pubmed publisher |
- immunocytochemistry; human; 1:400; fig s2
| Austen K, Ringer P, Mehlich A, Chrostek Grashoff A, Kluger C, Klingner C, et al. Extracellular rigidity sensing by talin isoform-specific mechanical linkages. Nat Cell Biol. 2015;17:1597-606 pubmed publisher |
- immunocytochemistry; mouse; fig 2
| Kosmalska A, Casares L, Elosegui Artola A, Thottacherry J, Moreno Vicente R, González Tarragó V, et al. Physical principles of membrane remodelling during cell mechanoadaptation. Nat Commun. 2015;6:7292 pubmed publisher |
- western blot; human; 1:1000
| Case L, Baird M, Shtengel G, Campbell S, Hess H, Davidson M, et al. Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions. Nat Cell Biol. 2015;17:880-92 pubmed publisher |
- immunocytochemistry; human
| Fukumoto M, Kurisu S, Yamada T, Takenawa T. α-Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturation. PLoS ONE. 2015;10:e0120616 pubmed publisher |
- immunocytochemistry; human; 1:200; fig 6
- western blot; mouse; 1:1000; fig 1
| Robertson J, Jacquemet G, Byron A, Jones M, Warwood S, Selley J, et al. Defining the phospho-adhesome through the phosphoproteomic analysis of integrin signalling. Nat Commun. 2015;6:6265 pubmed publisher |
| Ng D, Humphries J, Byron A, Millon Frémillon A, Humphries M. Microtubule-dependent modulation of adhesion complex composition. PLoS ONE. 2014;9:e115213 pubmed publisher |
- western blot; human; fig 6
| Gill M, Turner R, Stevenson P, Way M. KSHV-TK is a tyrosine kinase that disrupts focal adhesions and induces Rho-mediated cell contraction. EMBO J. 2015;34:448-65 pubmed publisher |
- immunocytochemistry; human; 10 ug/ml; fig 2
| Georgess D, Mazzorana M, Terrado J, Delprat C, Chamot C, Guasch R, et al. Comparative transcriptomics reveals RhoE as a novel regulator of actin dynamics in bone-resorbing osteoclasts. Mol Biol Cell. 2014;25:380-96 pubmed publisher |
| Bressan C, Pecora A, Gagnon D, Snapyan M, Labrecque S, De Koninck P, et al. The dynamic interplay between ATP/ADP levels and autophagy sustain neuronal migration in vivo. elife. 2020;9: pubmed publisher |
| Jain P, Guerreiro P, Canato S, Janody F. The spectraplakin Dystonin antagonizes YAP activity and suppresses tumourigenesis. Sci Rep. 2019;9:19843 pubmed publisher |
| Cortés E, Sarper M, Robinson B, Lachowski D, Chronopoulos A, Thorpe S, et al. GPER is a mechanoregulator of pancreatic stellate cells and the tumor microenvironment. EMBO Rep. 2019;20: pubmed publisher |
| Ikeuchi T, de Vega S, Forcinito P, Doyle A, Amaral J, Rodriguez I, et al. Extracellular Protein Fibulin-7 and Its C-Terminal Fragment Have In Vivo Antiangiogenic Activity. Sci Rep. 2018;8:17654 pubmed publisher |
| Liao G, Wang R, Rezey A, Gerlach B, Tang D. MicroRNA miR-509 Regulates ERK1/2, the Vimentin Network, and Focal Adhesions by Targeting Plk1. Sci Rep. 2018;8:12635 pubmed publisher |
| Panagiotakopoulou M, Lendenmann T, Pramotton F, Giampietro C, Stefopoulos G, Poulikakos D, et al. Cell cycle-dependent force transmission in cancer cells. Mol Biol Cell. 2018;29:2528-2539 pubmed publisher |
| Chen P, Muzumdar M, Dorans K, Robbins R, Bhutkar A, Del Rosario A, et al. Adaptive and Reversible Resistance to Kras Inhibition in Pancreatic Cancer Cells. Cancer Res. 2018;78:985-1002 pubmed publisher |
| Zhu L, Yang J, Bromberger T, Holly A, Lu F, Liu H, et al. Structure of Rap1b bound to talin reveals a pathway for triggering integrin activation. Nat Commun. 2017;8:1744 pubmed publisher |
| Mizoguchi T, Ikeda S, Watanabe S, Sugawara M, Itoh M. Mib1 contributes to persistent directional cell migration by regulating the Ctnnd1-Rac1 pathway. Proc Natl Acad Sci U S A. 2017;114:E9280-E9289 pubmed publisher |
| Luo W, Janostiak R, Tolde O, Ryzhova L, Koudelková L, Dibus M, et al. ARHGAP42 is activated by Src-mediated tyrosine phosphorylation to promote cell motility. J Cell Sci. 2017;130:2382-2393 pubmed publisher |
| Goicoechea S, Zinn A, Awadia S, Snyder K, Garcia Mata R. A RhoG-mediated signaling pathway that modulates invadopodia dynamics in breast cancer cells. J Cell Sci. 2017;130:1064-1077 pubmed publisher |
| Mercey O, Popa A, Cavard A, Paquet A, Chevalier B, Pons N, et al. Characterizing isomiR variants within the microRNA-34/449 family. FEBS Lett. 2017;591:693-705 pubmed publisher |
| Lim I, Joo H, Jeong M, Kim J, Choi S, Kim C, et al. Talin Modulation by a Synthetic N-Acylurea Derivative Reduces Angiogenesis in Human Endothelial Cells. Int J Mol Sci. 2017;18: pubmed publisher |
| Albecka A, Owen D, Ivanova L, Brun J, Liman R, Davies L, et al. Dual Function of the pUL7-pUL51 Tegument Protein Complex in Herpes Simplex Virus 1 Infection. J Virol. 2017;91: pubmed publisher |
| Chronopoulos A, Robinson B, Sarper M, Cortés E, Auernheimer V, Lachowski D, et al. ATRA mechanically reprograms pancreatic stellate cells to suppress matrix remodelling and inhibit cancer cell invasion. Nat Commun. 2016;7:12630 pubmed publisher |
| Moazzam M, Ye L, Sun P, Kynaston H, Jiang W. Knockdown of WAVE3 impairs HGF induced migration and invasion of prostate cancer cells. Cancer Cell Int. 2015;15:51 pubmed publisher |
| Moshfegh Y, Bravo Cordero J, Miskolci V, Condeelis J, Hodgson L. A Trio-Rac1-Pak1 signalling axis drives invadopodia disassembly. Nat Cell Biol. 2014;16:574-86 pubmed publisher |
| Rognoni E, Widmaier M, Jakobson M, Ruppert R, Ussar S, Katsougkri D, et al. Kindlin-1 controls Wnt and TGF-? availability to regulate cutaneous stem cell proliferation. Nat Med. 2014;20:350-9 pubmed publisher |
| Yamazaki D, Itoh T, Miki H, Takenawa T. srGAP1 regulates lamellipodial dynamics and cell migratory behavior by modulating Rac1 activity. Mol Biol Cell. 2013;24:3393-405 pubmed publisher |
| Vyas S, Chesarone Cataldo M, Todorova T, Huang Y, Chang P. A systematic analysis of the PARP protein family identifies new functions critical for cell physiology. Nat Commun. 2013;4:2240 pubmed publisher |
| Kostourou V, Lechertier T, Reynolds L, Lees D, Baker M, Jones D, et al. FAK-heterozygous mice display enhanced tumour angiogenesis. Nat Commun. 2013;4:2020 pubmed publisher |
| Tezuka Y, Okada M, Tada Y, Yamauchi J, Nishigori H, Sanbe A. Regulation of neurite growth by inorganic pyrophosphatase 1 via JNK dephosphorylation. PLoS ONE. 2013;8:e61649 pubmed publisher |
| Matthews H, Delabre U, Rohn J, Guck J, Kunda P, Baum B. Changes in Ect2 localization couple actomyosin-dependent cell shape changes to mitotic progression. Dev Cell. 2012;23:371-83 pubmed publisher |
| Lahlou H, Sanguin Gendreau V, Frame M, Muller W. Focal adhesion kinase contributes to proliferative potential of ErbB2 mammary tumour cells but is dispensable for ErbB2 mammary tumour induction in vivo. Breast Cancer Res. 2012;14:R36 pubmed |
| Hewer R, Sala Newby G, Wu Y, Newby A, Bond M. PKA and Epac synergistically inhibit smooth muscle cell proliferation. J Mol Cell Cardiol. 2011;50:87-98 pubmed publisher |
| Millan J, Cain R, Reglero Real N, Bigarella C, Marcos Ramiro B, Fernández Martín L, et al. Adherens junctions connect stress fibres between adjacent endothelial cells. BMC Biol. 2010;8:11 pubmed publisher |
| ten Klooster J, Jaffer Z, Chernoff J, Hordijk P. Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix. J Cell Biol. 2006;172:759-69 pubmed |
