product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
CD21/CD35
catalog :
562796
quantity :
0.1 mg
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
7G6
reactivity :
mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 41
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 2g, 2i, e5c
Brown G, Ca xf1 ete P, Wang H, Medhavy A, Bones J, Roco J, et al. TLR7 gain-of-function genetic variation causes human lupus. Nature. 2022;605:349-356 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2d
Luo R, Cheng Y, Chang D, Liu T, Liu L, Pei G, et al. Tertiary lymphoid organs are associated with the progression of kidney damage and regulated by interleukin-17A. Theranostics. 2021;11:117-131 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3e
Zhang Q, Xiang L, Zaman M, Dong W, He G, Deng G. Predominant Role of Immunoglobulin G in the Pathogenesis of Splenomegaly in Murine Lupus. Front Immunol. 2019;10:3020 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s9b
Zhao X, Xie H, Zhao M, Ahsan A, Li X, Wang F, et al. Fc receptor-like 1 intrinsically recruits c-Abl to enhance B cell activation and function. Sci Adv. 2019;5:eaaw0315 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3a
Hobeika E, Dautzenberg M, Levit Zerdoun E, Pelanda R, Reth M. Conditional Selection of B Cells in Mice With an Inducible B Cell Development. Front Immunol. 2018;9:1806 pubmed publisher
  • flow cytometry; mouse; 1:500; loading ...; fig s4e
Zhang C, Wang C, Jiang M, Gu C, Xiao J, Chen X, et al. Act1 is a negative regulator in T and B cells via direct inhibition of STAT3. Nat Commun. 2018;9:2745 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 2e
Inoue T, Shinnakasu R, Ise W, Kawai C, Egawa T, Kurosaki T. The transcription factor Foxo1 controls germinal center B cell proliferation in response to T cell help. J Exp Med. 2017;214:1181-1198 pubmed publisher
  • flow cytometry; mouse; fig s1b
Leeth C, Racine J, Chapman H, Arpa B, Carrillo J, Carrascal J, et al. B-lymphocytes expressing an Ig specificity recognizing the pancreatic ß-cell autoantigen peripherin are potent contributors to type 1 diabetes development in NOD mice. Diabetes. 2016;65:1977-1987 pubmed publisher
  • flow cytometry; mouse; fig 1
Fontinha D, Lopes F, Marques S, Alenquer M, Simas J. Murid Gammaherpesvirus Latency-Associated Protein M2 Promotes the Formation of Conjugates between Transformed B Lymphoma Cells and T Helper Cells. PLoS ONE. 2015;10:e0142540 pubmed publisher
  • flow cytometry; mouse
Kolhatkar N, Brahmandam A, Thouvenel C, Becker Herman S, Jacobs H, Schwartz M, et al. Altered BCR and TLR signals promote enhanced positive selection of autoreactive transitional B cells in Wiskott-Aldrich syndrome. J Exp Med. 2015;212:1663-77 pubmed publisher
  • flow cytometry; mouse
Sin S, Kim Y, Eason A, Dittmer D. KSHV Latency Locus Cooperates with Myc to Drive Lymphoma in Mice. PLoS Pathog. 2015;11:e1005135 pubmed publisher
  • immunohistochemistry; mouse; fig 3
Donaldson D, Else K, Mabbott N. The Gut-Associated Lymphoid Tissues in the Small Intestine, Not the Large Intestine, Play a Major Role in Oral Prion Disease Pathogenesis. J Virol. 2015;89:9532-47 pubmed publisher
  • flow cytometry; mouse
Jacque E, Schweighoffer E, Tybulewicz V, Ley S. BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival. J Exp Med. 2015;212:883-92 pubmed publisher
  • flow cytometry; mouse; fig 2
Yu J, Hoffman S, Beal A, Dykon A, Ringenberg M, Hughes A, et al. MALT1 Protease Activity Is Required for Innate and Adaptive Immune Responses. PLoS ONE. 2015;10:e0127083 pubmed publisher
  • immunocytochemistry; mouse
Moalli F, Proulx S, Schwendener R, Detmar M, Schlapbach C, Stein J. Intravital and whole-organ imaging reveals capture of melanoma-derived antigen by lymph node subcapsular macrophages leading to widespread deposition on follicular dendritic cells. Front Immunol. 2015;6:114 pubmed publisher
  • flow cytometry; mouse; 1:200; fig 4d
Pratama A, Srivastava M, Williams N, Papa I, Lee S, Dinh X, et al. MicroRNA-146a regulates ICOS-ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres. Nat Commun. 2015;6:6436 pubmed publisher
  • immunohistochemistry; mouse
Donaldson D, Bradford B, Artis D, Mabbott N. Reciprocal regulation of lymphoid tissue development in the large intestine by IL-25 and IL-23. Mucosal Immunol. 2015;8:582-95 pubmed publisher
  • flow cytometry; mouse
Chen M, Chen Y, Wu M, Yu G, Lin W, Tan T, et al. PP4 is essential for germinal center formation and class switch recombination in mice. PLoS ONE. 2014;9:e107505 pubmed publisher
  • flow cytometry; mouse; fig 1
Schwartz M, Kolhatkar N, Thouvenel C, Khim S, Rawlings D. CD4+ T cells and CD40 participate in selection and homeostasis of peripheral B cells. J Immunol. 2014;193:3492-502 pubmed publisher
  • flow cytometry; mouse
Honjo K, Kubagawa Y, Suzuki Y, Takagi M, Ohno H, Bucy R, et al. Enhanced auto-antibody production and Mott cell formation in Fc?R-deficient autoimmune mice. Int Immunol. 2014;26:659-72 pubmed publisher
  • flow cytometry; mouse; tbl 1
Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L, et al. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells. Nat Immunol. 2014;15:354-364 pubmed publisher
  • flow cytometry; mouse
Coffey F, Manser T. Expression of cellular FLIP by B cells is required for their participation in an immune response. J Immunol. 2010;184:4871-9 pubmed publisher
Cooley L, El Shikh M, Li W, Keim R, Zhang Z, Strauss J, et al. Impaired immunological synapse in sperm associated antigen 6 (SPAG6) deficient mice. Sci Rep. 2016;6:25840 pubmed publisher
Guikema J, Linehan E, Tsuchimoto D, Nakabeppu Y, Strauss P, Stavnezer J, et al. APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination. J Exp Med. 2007;204:3017-26 pubmed
Hövelmeyer N, Wunderlich F, Massoumi R, Jakobsen C, Song J, Wörns M, et al. Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD. J Exp Med. 2007;204:2615-27 pubmed
Horikawa K, Martin S, Pogue S, Silver K, Peng K, Takatsu K, et al. Enhancement and suppression of signaling by the conserved tail of IgG memory-type B cell antigen receptors. J Exp Med. 2007;204:759-69 pubmed
Matter M, Odermatt B, Yagita H, Nuoffer J, Ochsenbein A. Elimination of chronic viral infection by blocking CD27 signaling. J Exp Med. 2006;203:2145-55 pubmed
Wheway J, Mackay C, Newton R, Sainsbury A, Boey D, Herzog H, et al. A fundamental bimodal role for neuropeptide Y1 receptor in the immune system. J Exp Med. 2005;202:1527-38 pubmed
Chen T, Li L, Chung D, Allen C, Torti S, Torti F, et al. TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis. J Exp Med. 2005;202:955-65 pubmed
Cobas M, Wilson A, Ernst B, Mancini S, MacDonald H, Kemler R, et al. Beta-catenin is dispensable for hematopoiesis and lymphopoiesis. J Exp Med. 2004;199:221-9 pubmed
Bell J, Gray D. Antigen-capturing cells can masquerade as memory B cells. J Exp Med. 2003;197:1233-44 pubmed
Phan T, Amesbury M, Gardam S, Crosbie J, Hasbold J, Hodgkin P, et al. B cell receptor-independent stimuli trigger immunoglobulin (Ig) class switch recombination and production of IgG autoantibodies by anergic self-reactive B cells. J Exp Med. 2003;197:845-60 pubmed
Li Y, Li H, Ni D, Weigert M. Anti-DNA B cells in MRL/lpr mice show altered differentiation and editing pattern. J Exp Med. 2002;196:1543-52 pubmed
Xu S, Lam K. Delayed cellular maturation and decreased immunoglobulin kappa light chain production in immature B lymphocytes lacking B cell linker protein. J Exp Med. 2002;196:197-206 pubmed
Wardemann H, Boehm T, Dear N, Carsetti R. B-1a B cells that link the innate and adaptive immune responses are lacking in the absence of the spleen. J Exp Med. 2002;195:771-80 pubmed
Bowman E, Kuklin N, Youngman K, Lazarus N, Kunkel E, Pan J, et al. The intestinal chemokine thymus-expressed chemokine (CCL25) attracts IgA antibody-secreting cells. J Exp Med. 2002;195:269-75 pubmed
Schneider P, Takatsuka H, Wilson A, Mackay F, Tardivel A, Lens S, et al. Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen. J Exp Med. 2001;194:1691-7 pubmed
Hao Z, Rajewsky K. Homeostasis of peripheral B cells in the absence of B cell influx from the bone marrow. J Exp Med. 2001;194:1151-64 pubmed
Carvalho T, Mota Santos T, Cumano A, Demengeot J, Vieira P. Arrested B lymphopoiesis and persistence of activated B cells in adult interleukin 7(-/)- mice. J Exp Med. 2001;194:1141-50 pubmed
Ruiz Vela A, Serrano F, Gonzalez M, Abad J, Bernad A, Maki M, et al. Transplanted long-term cultured pre-BI cells expressing calpastatin are resistant to B cell receptor-induced apoptosis. J Exp Med. 2001;194:247-54 pubmed
Flaishon L, Hershkoviz R, Lantner F, Lider O, Alon R, Levo Y, et al. Autocrine secretion of interferon gamma negatively regulates homing of immature B cells. J Exp Med. 2000;192:1381-8 pubmed
product information
Cat.# :
562796
Brand :
BD Pharmingen
Name :
CD21/CD35
Format :
Biotin
Clone :
7G6
Isotype :
Rat IgG 2b
React :
Ms
Conc :
0.5 mg/ml
Apps :
FCM
Size :
0.1 mg
Status :
RUO
more info or order :
company information