Liu Y, Du J, Liu X, Wang L, Han Y, Huang C, et al. MG149 inhibits histone acetyltransferase KAT8-mediated IL-33 acetylation to alleviate allergic airway inflammation and airway hyperresponsiveness. Signal Transduct Target Ther. 2021;6:321 pubmed publisher

Kong W, Tsuyama N, Inoue H, Guo Y, Mokuda S, Nobukiyo A, et al. Long-chain saturated fatty acids in breast milk are associated with the pathogenesis of atopic dermatitis via induction of inflammatory ILC3s. Sci Rep. 2021;11:13109 pubmed publisher

Aslam M, Alemdehy M, Kwesi Maliepaard E, Muhaimin F, Caganova M, Pardieck I, et al. Histone methyltransferase DOT1L controls state-specific identity during B cell differentiation. EMBO Rep. 2021;22:e51184 pubmed publisher

Jacome Galarza C, Percin G, Muller J, Mass E, Lazarov T, Eitler J, et al. Developmental origin, functional maintenance and genetic rescue of osteoclasts. Nature. 2019;568:541-545 pubmed publisher

Garaycoechea J, Crossan G, Langevin F, Mulderrig L, Louzada S, Yang F, et al. Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. Nature. 2018;553:171-177 pubmed publisher

Cuccarese M, Dubach J, Pfirschke C, Engblom C, Garris C, Miller M, et al. Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging. Nat Commun. 2017;8:14293 pubmed publisher

Kunimoto H, McKenney A, Meydan C, Shank K, Nazir A, Rapaport F, et al. Aid is a key regulator of myeloid/erythroid differentiation and DNA methylation in hematopoietic stem/progenitor cells. Blood. 2017;129:1779-1790 pubmed publisher

Rux D, Song J, Swinehart I, Pineault K, Schlientz A, Trulik K, et al. Regionally Restricted Hox Function in Adult Bone Marrow Multipotent Mesenchymal Stem/Stromal Cells. Dev Cell. 2016;39:653-666 pubmed publisher

Theurl I, Hilgendorf I, Nairz M, Tymoszuk P, Haschka D, Asshoff M, et al. On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver. Nat Med. 2016;22:945-51 pubmed publisher

Goto Y, Aoyama M, Sekiya T, Kakita H, Waguri Nagaya Y, Miyazawa K, et al. CXCR4+ CD45- Cells are Niche Forming for Osteoclastogenesis via the SDF-1, CXCL7, and CX3CL1 Signaling Pathways in Bone Marrow. Stem Cells. 2016;34:2733-2743 pubmed publisher

Rios A, Fu N, Jamieson P, Pal B, Whitehead L, Nicholas K, et al. Essential role for a novel population of binucleated mammary epithelial cells in lactation. Nat Commun. 2016;7:11400 pubmed publisher

Miller M, Rosten P, Lemieux M, Lai C, Humphries R. Meis1 Is Required for Adult Mouse Erythropoiesis, Megakaryopoiesis and Hematopoietic Stem Cell Expansion. PLoS ONE. 2016;11:e0151584 pubmed publisher

Lasigliè D, Boero S, Bauer I, Morando S, Damonte P, Cea M, et al. Sirt6 regulates dendritic cell differentiation, maturation, and function. Aging (Albany NY). 2016;8:34-49 pubmed

Tsukui T, Ueha S, Shichino S, Inagaki Y, Matsushima K. Intratracheal cell transfer demonstrates the profibrotic potential of resident fibroblasts in pulmonary fibrosis. Am J Pathol. 2015;185:2939-48 pubmed publisher

Zhang J, Li L, Baldwin A, Friedman A, Paz Priel I. Loss of IKKβ but Not NF-κB p65 Skews Differentiation towards Myeloid over Erythroid Commitment and Increases Myeloid Progenitor Self-Renewal and Functional Long-Term Hematopoietic Stem Cells. PLoS ONE. 2015;10:e0130441 pubmed publisher

Kim B, Lee J, Choi J, Park D, Song H, Park T, et al. Imidazole-based alkaloid derivative LCB54-0009 suppresses ocular angiogenesis and lymphangiogenesis in models of experimental retinopathy and corneal neovascularization. Br J Pharmacol. 2015;172:3875-89 pubmed publisher

Spada R, Rojas J, Pérez Yagüe S, Mulens V, Cannata Ortiz P, Bragado R, et al. NKG2D ligand overexpression in lupus nephritis correlates with increased NK cell activity and differentiation in kidneys but not in the periphery. J Leukoc Biol. 2015;97:583-98 pubmed publisher

Swee L, Lourido S, Bell G, Ingram J, Ploegh H. One-step enzymatic modification of the cell surface redirects cellular cytotoxicity and parasite tropism. ACS Chem Biol. 2015;10:460-5 pubmed publisher

Rai S, Tanaka H, Suzuki M, Ogoh H, Taniguchi Y, Morita Y, et al. Clathrin assembly protein CALM plays a critical role in KIT signaling by regulating its cellular transport from early to late endosomes in hematopoietic cells. PLoS ONE. 2014;9:e109441 pubmed publisher

Naik E, Webster J, DeVoss J, Liu J, Suriben R, Dixit V. Regulation of proximal T cell receptor signaling and tolerance induction by deubiquitinase Usp9X. J Exp Med. 2014;211:1947-55 pubmed publisher

Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L, et al. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells. Nat Immunol. 2014;15:354-364 pubmed publisher

Forand A, Beck L, Leroy C, Rousseau A, Boitez V, Cohen I, et al. EKLF-driven PIT1 expression is critical for mouse erythroid maturation in vivo and in vitro. Blood. 2013;121:666-78 pubmed publisher

Mece O, Houbaert D, Sassano M, Durré T, Maes H, Schaaf M, et al. Lipid droplet degradation by autophagy connects mitochondria metabolism to Prox1-driven expression of lymphatic genes and lymphangiogenesis. Nat Commun. 2022;13:2760 pubmed publisher

Zhao J, Xiu Y, Fu L, Dong Q, Borcherding N, Wang Y, et al. TIFAB accelerates MLL-AF9-Induced acute myeloid leukemia through upregulation of HOXA9. iScience. 2021;24:103425 pubmed publisher

Chan D, Xu J, Vujovic A, Wong N, Gordon V, de Rooij L, et al. Arhgef2 regulates mitotic spindle orientation in hematopoietic stem cells and is essential for productive hematopoiesis. Blood Adv. 2021;5:3120-3133 pubmed publisher

King A, Songdej D, Downes D, Beagrie R, Liu S, Buckley M, et al. Reactivation of a developmentally silenced embryonic globin gene. Nat Commun. 2021;12:4439 pubmed publisher

Gocho Y, Liu J, Hu J, Yang W, Dharia N, Zhang J, et al. Network-based systems pharmacology reveals heterogeneity in LCK and BCL2 signaling and therapeutic sensitivity of T-cell acute lymphoblastic leukemia. Nat Cancer. 2021;2:284-299 pubmed publisher

Sacchetti A, Teeuwssen M, Verhagen M, Joosten R, Xu T, Stabile R, et al. Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer. elife. 2021;10: pubmed publisher

Goldfarb A, Freeman K, Sahu R, Elagib K, Holy M, Arneja A, et al. Iron control of erythroid microtubule cytoskeleton as a potential target in treatment of iron-restricted anemia. Nat Commun. 2021;12:1645 pubmed publisher

Krzeptowski W, Chudy P, Sokołowski G, Zukowska M, Kusienicka A, Seretny A, et al. Proximity Ligation Assay Detection of Protein-DNA Interactions-Is There a Link between Heme Oxygenase-1 and G-quadruplexes?. Antioxidants (Basel). 2021;10: pubmed publisher

Drijvers J, Gillis J, Muijlwijk T, Nguyen T, Gaudiano E, Harris I, et al. Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells. Cancer Immunol Res. 2021;9:184-199 pubmed publisher

Robledo R, Ciciotte S, Graber J, Zhao Y, Lambert A, Gwynn B, et al. Differential effects of RASA3 mutations on hematopoiesis are profoundly influenced by genetic background and molecular variant. PLoS Genet. 2020;16:e1008857 pubmed publisher

Hung C, Wang K, Liou Y, Wang J, Huang A, Lee T, et al. Negative Regulation of the Differentiation of Flk2- CD34- LSK Hematopoietic Stem Cells by EKLF/KLF1. Int J Mol Sci. 2020;21: pubmed publisher

Chen Z, Cheng L, Zhang J, Cui X. Angelica sinensis polysaccharide prevents mitochondrial apoptosis by regulating the Treg/Th17 ratio in aplastic anemia. BMC Complement Med Ther. 2020;20:192 pubmed publisher

Yang L, Chen Z, Stout E, Delerue F, Ittner L, Wilkins M, et al. Methylation of a CGATA element inhibits binding and regulation by GATA-1. Nat Commun. 2020;11:2560 pubmed publisher

Tummers B, Mari L, Guy C, Heckmann B, Rodriguez D, Rühl S, et al. Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis. Immunity. 2020;52:994-1006.e8 pubmed publisher

D Altri T, Wilhelmson A, Schuster M, Wenzel A, Kalvisa A, Pundhir S, et al. The ASXL1-G643W variant accelerates the development of CEBPA mutant acute myeloid leukemia. Haematologica. 2020;: pubmed publisher

Knights A, Yang L, Shah M, Norton L, Green G, Stout E, et al. Krüppel-like factor 3 (KLF3) suppresses NF-κB-driven inflammation in mice. J Biol Chem. 2020;295:6080-6091 pubmed publisher

Hilchey S, Palshikar M, Emo J, Li D, Garigen J, Wang J, et al. Cyclosporine a directly affects human and mouse b cell migration in vitro by disrupting a hIF-1 αdependent, o2 sensing, molecular switch. BMC Immunol. 2020;21:13 pubmed publisher

Houri K, Mori T, Onodera Y, Tsujimoto T, Takehara T, Nakao S, et al. miR-142 induces accumulation of reactive oxygen species (ROS) by inhibiting pexophagy in aged bone marrow mesenchymal stem cells. Sci Rep. 2020;10:3735 pubmed publisher

van Gastel N, Stegen S, Eelen G, Schoors S, Carlier A, Daniëls V, et al. Lipid availability determines fate of skeletal progenitor cells via SOX9. Nature. 2020;579:111-117 pubmed publisher

Rottmann M, Jonat B, Gumpp C, Dhingra S, Giddins M, Yin X, et al. Preclinical Antimalarial Combination Study of M5717, a Plasmodium falciparum Elongation Factor 2 Inhibitor, and Pyronaridine, a Hemozoin Formation Inhibitor. Antimicrob Agents Chemother. 2020;64: pubmed publisher

Okumura G, Iguchi Manaka A, Murata R, Yamashita Kanemaru Y, Shibuya A, Shibuya K. Tumor-derived soluble CD155 inhibits DNAM-1-mediated antitumor activity of natural killer cells. J Exp Med. 2020;217: pubmed publisher

Fu R, Lv W, Xu Y, Gong M, Chen X, Jiang N, et al. Endothelial ZEB1 promotes angiogenesis-dependent bone formation and reverses osteoporosis. Nat Commun. 2020;11:460 pubmed publisher

Yoo H, Lee Y, Park C, Son D, Choi D, Park J, et al. Epigenetic priming by Dot1l in lymphatic endothelial progenitors ensures normal lymphatic development and function. Cell Death Dis. 2020;11:14 pubmed publisher

Collins K, Kang H, Matsche J, Klomp J, Rehman J, Malik A, et al. Septin2 mediates podosome maturation and endothelial cell invasion associated with angiogenesis. J Cell Biol. 2020;219: pubmed publisher

Tasdogan A, Faubert B, Ramesh V, Ubellacker J, Shen B, Solmonson A, et al. Metabolic heterogeneity confers differences in melanoma metastatic potential. Nature. 2020;577:115-120 pubmed publisher

de Roo J, Vloemans S, Vrolijk H, de Haas E, Staal F. Development of an in vivo model to study clonal lineage relationships in hematopoietic cells using Brainbow2.1/Confetti mice. Future Sci OA. 2019;5:FSO427 pubmed publisher

Beauchemin H, Shooshtharizadeh P, Pinder J, Dellaire G, Moroy T. Dominant negative Gfi1b mutations cause moderate thrombocytopenia and an impaired stress thrombopoiesis associated with mild erythropoietic abnormalities in mice. Haematologica. 2019;: pubmed publisher

Zheng W, Zhang H, Zhao D, Zhang J, Pollard J. Lung Mammary Metastases but Not Primary Tumors Induce Accumulation of Atypical Large Platelets and Their Chemokine Expression. Cell Rep. 2019;29:1747-1755.e4 pubmed publisher

Shehata L, Maurer D, Wec A, Lilov A, Champney E, Sun T, et al. Affinity Maturation Enhances Antibody Specificity but Compromises Conformational Stability. Cell Rep. 2019;28:3300-3308.e4 pubmed publisher

Onodera Y, Teramura T, Takehara T, Fukuda K. Transforming Growth Factor β-Activated Kinase 1 Regulates Mesenchymal Stem Cell Proliferation Through Stabilization of Yap1/Taz Proteins. Stem Cells. 2019;37:1595-1605 pubmed publisher

Wang N, Fan Y, Yuan C, Song J, Yao Y, Liu W, et al. Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity. BMC Cancer. 2019;19:764 pubmed publisher

Fang Y, Zhu L, An N, Jiang G, Qian J, Zhao R, et al. Blood autophagy defect causes accelerated non-hematopoietic organ aging. Aging (Albany NY). 2019;11:4910-4922 pubmed publisher

Pineault K, Song J, Kozloff K, Lucas D, Wellik D. Hox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life. Nat Commun. 2019;10:3168 pubmed publisher

Gross K, Zhou W, Breindel J, Ouyang J, Jin D, Sokol E, et al. Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium. Cell Rep. 2019;28:394-407.e6 pubmed publisher

Park S, Lee C, Dever D, Davis T, Camarena J, Srifa W, et al. Highly efficient editing of the β-globin gene in patient-derived hematopoietic stem and progenitor cells to treat sickle cell disease. Nucleic Acids Res. 2019;47:7955-7972 pubmed publisher

Borot F, Wang H, Ma Y, Jafarov T, Raza A, Ali A, et al. Gene-edited stem cells enable CD33-directed immune therapy for myeloid malignancies. Proc Natl Acad Sci U S A. 2019;116:11978-11987 pubmed publisher

Peng L, Guo H, Ma P, Sun Y, Dennison L, Aplan P, et al. HoxA9 binds and represses the Cebpa +8 kb enhancer. PLoS ONE. 2019;14:e0217604 pubmed publisher

Fernández Chacón M, Casquero García V, Luo W, Francesca Lunella F, Ferreira Rocha S, Del Olmo Cabrera S, et al. iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications. Nat Commun. 2019;10:2262 pubmed publisher

Goldstein J, Tabebordbar M, Zhu K, Wang L, Messemer K, Peacker B, et al. In Situ Modification of Tissue Stem and Progenitor Cell Genomes. Cell Rep. 2019;27:1254-1264.e7 pubmed publisher

Mayers S, Moço P, Maqbool T, Silva P, Kilkenny D, Audet J. Establishment of an erythroid progenitor cell line capable of enucleation achieved with an inducible c-Myc vector. BMC Biotechnol. 2019;19:21 pubmed publisher

Abdulhay N, Fiorini C, Verboon J, Ludwig L, Ulirsch J, Zieger B, et al. Impaired human hematopoiesis due to a cryptic intronic GATA1 splicing mutation. J Exp Med. 2019;216:1050-1060 pubmed publisher

Cheng P, Eksioglu E, Chen X, Kandell W, Le Trinh T, Cen L, et al. S100A9-induced overexpression of PD-1/PD-L1 contributes to ineffective hematopoiesis in myelodysplastic syndromes. Leukemia. 2019;: pubmed publisher

Santana Codina N, Gableske S, Quiles Del Rey M, Małachowska B, Jedrychowski M, Biancur D, et al. NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms. Haematologica. 2019;: pubmed publisher

Lu R, Czechowicz A, Seita J, Jiang D, Weissman I. Clonal-level lineage commitment pathways of hematopoietic stem cells in vivo. Proc Natl Acad Sci U S A. 2019;116:1447-1456 pubmed publisher

Selimoglu Buet D, Rivière J, Ghamlouch H, Bencheikh L, Lacout C, Morabito M, et al. A miR-150/TET3 pathway regulates the generation of mouse and human non-classical monocyte subset. Nat Commun. 2018;9:5455 pubmed publisher

Szappanos D, Tschismarov R, Perlot T, Westermayer S, Fischer K, Platanitis E, et al. The RNA helicase DDX3X is an essential mediator of innate antimicrobial immunity. PLoS Pathog. 2018;14:e1007397 pubmed publisher

Nakagawa M, RATHINAM C. Constitutive Activation of the Canonical NF-κB Pathway Leads to Bone Marrow Failure and Induction of Erythroid Signature in Hematopoietic Stem Cells. Cell Rep. 2018;25:2094-2109.e4 pubmed publisher

Cagnet S, Ataca D, Sflomos G, Aouad P, Schuepbach Mallepell S, Hugues H, et al. Oestrogen receptor α AF-1 and AF-2 domains have cell population-specific functions in the mammary epithelium. Nat Commun. 2018;9:4723 pubmed publisher

Aries I, Bodaar K, Karim S, Chonghaile T, Hinze L, Burns M, et al. PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia. J Exp Med. 2018;215:3094-3114 pubmed publisher

Kelly A, Günaltay S, McEntee C, Shuttleworth E, Smedley C, Houston S, et al. Human monocytes and macrophages regulate immune tolerance via integrin αvβ8-mediated TGFβ activation. J Exp Med. 2018;215:2725-2736 pubmed publisher

Chandra S, Gray J, Kiosses W, Khurana A, Hitomi K, Crosby C, et al. Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae. Nat Commun. 2018;9:4279 pubmed publisher

Lobo N, Zabala M, Qian D, Clarke M. Serially transplantable mammary epithelial cells express the Thy-1 antigen. Breast Cancer Res. 2018;20:121 pubmed publisher

Das P, Veazey K, Van H, Kaushik S, Lin K, Lu Y, et al. Histone methylation regulator PTIP is required to maintain normal and leukemic bone marrow niches. Proc Natl Acad Sci U S A. 2018;115:E10137-E10146 pubmed publisher

Wang A, Huen S, Luan H, Baker K, Rinder H, Booth C, et al. Glucose metabolism mediates disease tolerance in cerebral malaria. Proc Natl Acad Sci U S A. 2018;115:11042-11047 pubmed publisher

Giambra V, Gusscott S, Gracias D, Song R, Lam S, Panelli P, et al. Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity. Cell Stem Cell. 2018;23:714-726.e7 pubmed publisher

Harwood F, Klein Geltink R, O Hara B, Cardone M, Janke L, Finkelstein D, et al. ETV7 is an essential component of a rapamycin-insensitive mTOR complex in cancer. Sci Adv. 2018;4:eaar3938 pubmed publisher

Debnath S, Yallowitz A, McCormick J, Lalani S, Zhang T, Xu R, et al. Discovery of a periosteal stem cell mediating intramembranous bone formation. Nature. 2018;562:133-139 pubmed publisher

Brown J, Roberts N, Graham B, Waithe D, Lagerholm C, Telenius J, et al. A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions. Nat Commun. 2018;9:3849 pubmed publisher

Chen M, Hsu W, Hsu S, Yang Y, Chuang T, Lin W, et al. PP4 deficiency leads to DNA replication stress that impairs immunoglobulin class switch efficiency. Cell Death Differ. 2019;26:1221-1234 pubmed publisher

Singhal M, Liu X, Inverso D, Jiang K, Dai J, He H, et al. Endothelial cell fitness dictates the source of regenerating liver vasculature. J Exp Med. 2018;215:2497-2508 pubmed publisher

Hu P, Nebreda A, Hanenberg H, Kinnebrew G, Ivan M, Yoder M, et al. P38α/JNK signaling restrains erythropoiesis by suppressing Ezh2-mediated epigenetic silencing of Bim. Nat Commun. 2018;9:3518 pubmed publisher

Lei A, Xiao Q, Liu G, Shi K, Yang Q, Li X, et al. ICAM-1 controls development and function of ILC2. J Exp Med. 2018;215:2157-2174 pubmed publisher

Er E, Valiente M, Ganesh K, Zou Y, Agrawal S, Hu J, et al. Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization. Nat Cell Biol. 2018;20:966-978 pubmed publisher

Thyagarajan H, Lancaster J, Lira S, Ehrlich L. CCR8 is expressed by post-positive selection CD4-lineage thymocytes but is dispensable for central tolerance induction. PLoS ONE. 2018;13:e0200765 pubmed publisher

Wang C, Bai F, Zhang L, Scott A, Li E, Pei X. Estrogen promotes estrogen receptor negative BRCA1-deficient tumor initiation and progression. Breast Cancer Res. 2018;20:74 pubmed publisher

Liu Q, Wang Y, Wu Z, Shi Z, Wu X, Chen X, et al. High Mobility Group Protein 1 Reverses Immune System Paralysis in Late-Phase Sepsis. Infect Immun. 2018;86: pubmed publisher

Petvises S, Periasamy P, O Neill H. MCSF drives regulatory DC development in stromal co-cultures supporting hematopoiesis. BMC Immunol. 2018;19:21 pubmed publisher

Kato K, Diéguez Hurtado R, Park D, Hong S, Kato Azuma S, Adams S, et al. Pulmonary pericytes regulate lung morphogenesis. Nat Commun. 2018;9:2448 pubmed publisher

Jensen C, Åhsberg J, Sommarin M, Strid T, Somasundaram R, Okuyama K, et al. Dissection of progenitor compartments resolves developmental trajectories in B-lymphopoiesis. J Exp Med. 2018;215:1947-1963 pubmed publisher

Alonso Martin S, Aurade F, Mademtzoglou D, Rochat A, Zammit P, Relaix F. SOXF factors regulate murine satellite cell self-renewal and function through inhibition of β-catenin activity. elife. 2018;7: pubmed publisher

Ghanem L, Kromer A, Silverman I, Ji X, Gazzara M, Nguyen N, et al. Poly(C)-Binding Protein Pcbp2 Enables Differentiation of Definitive Erythropoiesis by Directing Functional Splicing of the Runx1 Transcript. Mol Cell Biol. 2018;38: pubmed publisher

Li C, Psatha N, Sova P, Gil S, Wang H, Kim J, et al. Reactivation of ?-globin in adult ?-YAC mice after ex vivo and in vivo hematopoietic stem cell genome editing. Blood. 2018;: pubmed publisher

Li C, Luo Y, Shao L, Meng A, Zhou D. NOS2 deficiency has no influence on the radiosensitivity of the hematopoietic system. Cell Biosci. 2018;8:33 pubmed publisher

Gozdecka M, Meduri E, Mazan M, Tzelepis K, Dudek M, Knights A, et al. UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs. Nat Genet. 2018;50:883-894 pubmed publisher

Adamiak M, Bujko K, Cymer M, Plonka M, Glaser T, Kucia M, et al. Novel evidence that extracellular nucleotides and purinergic signaling induce innate immunity-mediated mobilization of hematopoietic stem/progenitor cells. Leukemia. 2018;32:1920-1931 pubmed publisher

Baba O, Horie T, Nakao T, Hakuno D, Nakashima Y, Nishi H, et al. MicroRNA 33 Regulates the Population of Peripheral Inflammatory Ly6Chigh Monocytes through Dual Pathways. Mol Cell Biol. 2018;38: pubmed publisher

Fang H, El Farran C, Xing Q, Zhang L, Li H, Lim B, et al. Global H3.3 dynamic deposition defines its bimodal role in cell fate transition. Nat Commun. 2018;9:1537 pubmed publisher

Patel R, Qing Y, Kennedy L, Yan Y, Pink J, Aguila B, et al. MMR Deficiency Does Not Sensitize or Compromise the Function of Hematopoietic Stem Cells to Low and High LET Radiation. Stem Cells Transl Med. 2018;7:513-520 pubmed publisher

Zhang Y, Xia F, Liu X, Yu Z, Xie L, Liu L, et al. JAM3 maintains leukemia-initiating cell self-renewal through LRP5/AKT/?-catenin/CCND1 signaling. J Clin Invest. 2018;128:1737-1751 pubmed publisher

Rubio Patiño C, Bossowski J, De Donatis G, Mondragon L, Villa E, Aira L, et al. Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance. Cell Metab. 2018;27:828-842.e7 pubmed publisher

Zhang Y, Tech L, George L, Acs A, Durrett R, Hess H, et al. Plasma cell output from germinal centers is regulated by signals from Tfh and stromal cells. J Exp Med. 2018;215:1227-1243 pubmed publisher

Chen C, Koenig A, Saison C, Dahdal S, Rigault G, Barba T, et al. CD4+ T Cell Help Is Mandatory for Naive and Memory Donor-Specific Antibody Responses: Impact of Therapeutic Immunosuppression. Front Immunol. 2018;9:275 pubmed publisher

Gallitz I, Lofruthe N, Traeger L, Baumer N, Hoerr V, Faber C, et al. Deficiency of the BMP Type I receptor ALK3 partly protects mice from anemia of inflammation. BMC Physiol. 2018;18:3 pubmed publisher

Tusi B, Wolock S, Weinreb C, Hwang Y, Hidalgo D, Zilionis R, et al. Population snapshots predict early haematopoietic and erythroid hierarchies. Nature. 2018;555:54-60 pubmed publisher

Patra D, DeLassus E, Mueller J, Abou Ezzi G, Sandell L. Site-1 protease regulates skeletal stem cell population and osteogenic differentiation in mice. Biol Open. 2018;7: pubmed publisher

Zhang R, Ma H, Gao Y, Wu Y, Qiao Y, Geng A, et al. Th-POK regulates mammary gland lactation through mTOR-SREBP pathway. PLoS Genet. 2018;14:e1007211 pubmed publisher

Periasamy S, Harton J. Interleukin 1α (IL-1α) Promotes Pathogenic Immature Myeloid Cells and IL-1β Favors Protective Mature Myeloid Cells During Acute Lung Infection. J Infect Dis. 2018;217:1481-1490 pubmed publisher

Vo L, Kinney M, Liu X, Zhang Y, Barragan J, Sousa P, et al. Regulation of embryonic haematopoietic multipotency by EZH1. Nature. 2018;553:506-510 pubmed publisher

Mensink M, Anstee N, Robati M, Schenk R, Herold M, Cory S, et al. Anti-apoptotic A1 is not essential for lymphoma development in Eµ-Myc mice but helps sustain transplanted Eµ-Myc tumour cells. Cell Death Differ. 2018;25:795-806 pubmed publisher

Chen J, Guccini I, Di Mitri D, Brina D, Revandkar A, Sarti M, et al. Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer. Nat Genet. 2018;50:219-228 pubmed publisher

Song A, Zhu L, Gorantla G, Berdysz O, Amici S, Guerau de Arellano M, et al. Salient type 1 interleukin 1 receptor expression in peripheral non-immune cells. Sci Rep. 2018;8:723 pubmed publisher

Khalil S, Delehanty L, Grado S, Holy M, White Z, Freeman K, et al. Iron modulation of erythropoiesis is associated with Scribble-mediated control of the erythropoietin receptor. J Exp Med. 2018;215:661-679 pubmed publisher

Fang X, Shen F, Lechauve C, Xu P, Zhao G, Itkow J, et al. miR-144/451 represses the LKB1/AMPK/mTOR pathway to promote red cell precursor survival during recovery from acute anemia. Haematologica. 2018;103:406-416 pubmed publisher

Perez Villalba A, Sirerol Piquer M, Belenguer G, Soriano Cantón R, Muñoz Manchado A, Villadiego J, et al. Synaptic Regulator α-Synuclein in Dopaminergic Fibers Is Essentially Required for the Maintenance of Subependymal Neural Stem Cells. J Neurosci. 2018;38:814-825 pubmed publisher

Garcia Santos D, Hamdi A, Saxova Z, Fillebeen C, Pantopoulos K, Horvathova M, et al. Inhibition of heme oxygenase ameliorates anemia and reduces iron overload in ?-thalassemia mouse model. Blood. 2017;: pubmed publisher

Singh P, Hoggatt J, Kamocka M, Mohammad K, Saunders M, Li H, et al. Neuropeptide Y regulates a vascular gateway for hematopoietic stem and progenitor cells. J Clin Invest. 2017;127:4527-4540 pubmed publisher

Fernández Ruiz D, Lau L, Ghazanfari N, Jones C, Ng W, Davey G, et al. Development of a Novel CD4+ TCR Transgenic Line That Reveals a Dominant Role for CD8+ Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-Stage Malaria. J Immunol. 2017;199:4165-4179 pubmed publisher

Hua W, Qi J, Cai Q, Carnahan E, Ayala Ramirez M, Li L, et al. HDAC8 regulates long-term hematopoietic stem-cell maintenance under stress by modulating p53 activity. Blood. 2017;130:2619-2630 pubmed publisher

Lee M, Tanabe O, Shi L, Jearawiriyapaisarn N, Lucas D, Engel J. The orphan nuclear receptor TR4 regulates erythroid cell proliferation and maturation. Blood. 2017;130:2537-2547 pubmed publisher

Mello S, Valente L, Raj N, Seoane J, Flowers B, McClendon J, et al. A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer. Cancer Cell. 2017;32:460-473.e6 pubmed publisher

Degn S, Alicot E, Carroll M. B cell tolerance to epidermal ribonuclear-associated neo-autoantigen in vivo. Clin Exp Immunol. 2017;: pubmed publisher

Dominguez S, Montgomery A, Haines G, Bloomfield C, Cuda C. The caspase-8/RIPK3 signaling axis in antigen presenting cells controls the inflammatory arthritic response. Arthritis Res Ther. 2017;19:224 pubmed publisher

Isoda T, Moore A, He Z, Chandra V, Aida M, Denholtz M, et al. Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate. Cell. 2017;171:103-119.e18 pubmed publisher

Xiao S, Shterev I, Zhang W, Young L, Shieh J, Moore M, et al. Sublethal Total Body Irradiation Causes Long-Term Deficits in Thymus Function by Reducing Lymphoid Progenitors. J Immunol. 2017;199:2701-2712 pubmed publisher

Jung K, Heishi T, Incio J, Huang Y, Beech E, Pinter M, et al. Targeting CXCR4-dependent immunosuppressive Ly6Clow monocytes improves antiangiogenic therapy in colorectal cancer. Proc Natl Acad Sci U S A. 2017;114:10455-10460 pubmed publisher

Lee J, Tammela T, Hofree M, Choi J, Marjanovic N, Han S, et al. Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6. Cell. 2017;170:1149-1163.e12 pubmed publisher

Wang Y, Newman M, Ackun Farmmer M, Baranello M, Sheu T, Puzas J, et al. Fracture-Targeted Delivery of β-Catenin Agonists via Peptide-Functionalized Nanoparticles Augments Fracture Healing. ACS Nano. 2017;11:9445-9458 pubmed publisher

Nawaz A, Aminuddin A, Kado T, Takikawa A, Yamamoto S, Tsuneyama K, et al. CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors. Nat Commun. 2017;8:286 pubmed publisher

Kim J, Kim Y, Kim J, Park D, Bae H, Lee D, et al. YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation. J Clin Invest. 2017;127:3441-3461 pubmed publisher

Wiede F, Dudakov J, Lu K, Dodd G, Butt T, Godfrey D, et al. PTPN2 regulates T cell lineage commitment and αβ versus γδ specification. J Exp Med. 2017;214:2733-2758 pubmed publisher

Shi X, Lin Y, Gao B, Zhang P. Impairment of Hematopoietic Precursor Cell Activation during the Granulopoietic Response to Bacteremia in Mice with Chronic-Plus-Binge Alcohol Administration. Infect Immun. 2017;85: pubmed publisher

Karmaus P, Herrada A, Guy C, Neale G, Dhungana Y, Long L, et al. Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF-mediated myelopoiesis. J Exp Med. 2017;214:2629-2647 pubmed publisher

Sui Z, Gokhin D, Nowak R, Guo X, An X, Fowler V. Stabilization of F-actin by tropomyosin isoforms regulates the morphology and mechanical behavior of red blood cells. Mol Biol Cell. 2017;28:2531-2542 pubmed publisher

Kaushik S, Liu F, Veazey K, Gao G, Das P, Neves L, et al. Genetic deletion or small-molecule inhibition of the arginine methyltransferase PRMT5 exhibit anti-tumoral activity in mouse models of MLL-rearranged AML. Leukemia. 2018;32:499-509 pubmed publisher

Freire A, Waghray A, Soares da Silva F, Resende T, Lee D, Pereira C, et al. Transient HES5 Activity Instructs Mesodermal Cells toward a Cardiac Fate. Stem Cell Reports. 2017;9:136-148 pubmed publisher

Stik G, Crequit S, Petit L, Durant J, Charbord P, Jaffredo T, et al. Extracellular vesicles of stromal origin target and support hematopoietic stem and progenitor cells. J Cell Biol. 2017;216:2217-2230 pubmed publisher

Dudakov J, Mertelsmann A, O Connor M, Jenq R, Velardi E, Young L, et al. Loss of thymic innate lymphoid cells leads to impaired thymopoiesis in experimental graft-versus-host disease. Blood. 2017;130:933-942 pubmed publisher

Matte Martone C, Liu J, Zhou M, Chikina M, Green D, Harty J, et al. Differential requirements for myeloid leukemia IFN-γ conditioning determine graft-versus-leukemia resistance and sensitivity. J Clin Invest. 2017;127:2765-2776 pubmed publisher

Ilsley M, Gillinder K, Magor G, Huang S, Bailey T, Crossley M, et al. Krüppel-like factors compete for promoters and enhancers to fine-tune transcription. Nucleic Acids Res. 2017;45:6572-6588 pubmed publisher

Cunningham C, Bergsbaken T, Fink P. Cutting Edge: Defective Aerobic Glycolysis Defines the Distinct Effector Function in Antigen-Activated CD8+ Recent Thymic Emigrants. J Immunol. 2017;198:4575-4580 pubmed publisher

Elagib K, Lu C, Mosoyan G, Khalil S, Zasadzińska E, Foltz D, et al. Neonatal expression of RNA-binding protein IGF2BP3 regulates the human fetal-adult megakaryocyte transition. J Clin Invest. 2017;127:2365-2377 pubmed publisher

Ganuza M, Hadland B, Chabot A, Li C, Kang G, Bernstein I, et al. Murine hemogenic endothelial precursors display heterogeneous hematopoietic potential ex vivo. Exp Hematol. 2017;51:25-35.e6 pubmed publisher

Eddens T, Elsegeiny W, Garcia Hernadez M, Castillo P, Trevejo Nuñez G, Serody K, et al. Pneumocystis-Driven Inducible Bronchus-Associated Lymphoid Tissue Formation Requires Th2 and Th17 Immunity. Cell Rep. 2017;18:3078-3090 pubmed publisher

Wang H, Qian L, Zhao Y, Mengarelli J, Adrianto I, Montgomery C, et al. Downregulation of E Protein Activity Augments an ILC2 Differentiation Program in the Thymus. J Immunol. 2017;198:3149-3156 pubmed publisher

Guidi N, Sacma M, Ständker L, Soller K, Marka G, Eiwen K, et al. Osteopontin attenuates aging-associated phenotypes of hematopoietic stem cells. EMBO J. 2017;36:840-853 pubmed publisher

Arthur C, Patel S, Smith N, Bennett A, Kamili N, Mener A, et al. Antigen Density Dictates Immune Responsiveness following Red Blood Cell Transfusion. J Immunol. 2017;198:2671-2680 pubmed publisher

Pleines I, Woods J, Chappaz S, Kew V, Foad N, Ballester Beltrán J, et al. Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia. J Clin Invest. 2017;127:814-829 pubmed publisher

Mohapatra B, Zutshi N, An W, Goetz B, Arya P, Bielecki T, et al. An essential role of CBL and CBL-B ubiquitin ligases in mammary stem cell maintenance. Development. 2017;144:1072-1086 pubmed publisher

Dev A, Asch R, Jachimowicz E, Rainville N, Johnson A, Greenfest Allen E, et al. Governing roles for Trib3 pseudokinase during stress erythropoiesis. Exp Hematol. 2017;49:48-55.e5 pubmed publisher

Ijaz F, Hatanaka Y, Hatanaka T, Tsutsumi K, Iwaki T, Umemura K, et al. Proper cytoskeletal architecture beneath the plasma membrane of red blood cells requires Ttll4. Mol Biol Cell. 2017;28:535-544 pubmed publisher

Dong Q, Gao H, Shi Y, Zhang F, Gu X, Wu A, et al. Aging is associated with an expansion of CD49fhi mammary stem cells that show a decline in function and increased transformation potential. Aging (Albany NY). 2016;8:2754-2776 pubmed publisher

Liu W, Yu W, Zhang J, Chan R, Loh M, Zhang Z, et al. Inhibition of the Gab2/PI3K/mTOR signaling ameliorates myeloid malignancy caused by Ptpn11 (Shp2) gain-of-function mutations. Leukemia. 2017;31:1415-1422 pubmed publisher

Zhang J, McCastlain K, Yoshihara H, Xu B, Chang Y, Churchman M, et al. Deregulation of DUX4 and ERG in acute lymphoblastic leukemia. Nat Genet. 2016;48:1481-1489 pubmed publisher

Mupo A, Seiler M, Sathiaseelan V, Pance A, Yang Y, Agrawal A, et al. Hemopoietic-specific Sf3b1-K700E knock-in mice display the splicing defect seen in human MDS but develop anemia without ring sideroblasts. Leukemia. 2017;31:720-727 pubmed publisher

Wilhelm K, Happel K, Eelen G, Schoors S, Oellerich M, Lim R, et al. FOXO1 couples metabolic activity and growth state in the vascular endothelium. Nature. 2016;529:216-20 pubmed publisher

Acar M, Kocherlakota K, Murphy M, Peyer J, Oguro H, Inra C, et al. Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal. Nature. 2015;526:126-30 pubmed publisher

Mandal M, Hamel K, Maienschein Cline M, Tanaka A, Teng G, Tuteja J, et al. Histone reader BRWD1 targets and restricts recombination to the Igk locus. Nat Immunol. 2015;16:1094-103 pubmed publisher

Åšmieszek A, Czyrek A, Basińska K, Trynda J, SkaradziÅ„ska A, SiudziÅ„ska A, et al. Effect of Metformin on Viability, Morphology, and Ultrastructure of Mouse Bone Marrow-Derived Multipotent Mesenchymal Stromal Cells and Balb/3T3 Embryonic Fibroblast Cell Line. Biomed Res Int. 2015;2015:769402 pubmed publisher

Cicchini M, Chakrabarti R, Kongara S, Price S, Nahar R, Lozy F, et al. Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity. Autophagy. 2014;10:2036-52 pubmed publisher

Saurabh K, Scherzer M, Shah P, Mims A, Lockwood W, Kraft A, et al. The PIM family of oncoproteins: small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets. Oncotarget. 2014;5:8503-14 pubmed

Vares G, Wang B, Ishii Ohba H, Nenoi M, Nakajima T. Diet-induced obesity modulates epigenetic responses to ionizing radiation in mice. PLoS ONE. 2014;9:e106277 pubmed publisher

Adorno M, Sikandar S, Mitra S, Kuo A, Nicolis Di Robilant B, Haro Acosta V, et al. Usp16 contributes to somatic stem-cell defects in Down's syndrome. Nature. 2013;501:380-4 pubmed publisher

Tanaka R, Vaynrub M, Masuda H, Ito R, Kobori M, Miyasaka M, et al. Quality-control culture system restores diabetic endothelial progenitor cell vasculogenesis and accelerates wound closure. Diabetes. 2013;62:3207-17 pubmed publisher

Gillis L, Berry D, Minden M, McGlade C, Barber D. Gads (Grb2-related adaptor downstream of Shc) is required for BCR-ABL-mediated lymphoid leukemia. Leukemia. 2013;27:1666-76 pubmed publisher

Mandal M, Powers S, Maienschein Cline M, Bartom E, Hamel K, Kee B, et al. Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2. Nat Immunol. 2011;12:1212-20 pubmed publisher

Au Yeung B, Levin S, Zhang C, Hsu L, Cheng D, Killeen N, et al. A genetically selective inhibitor demonstrates a function for the kinase Zap70 in regulatory T cells independent of its catalytic activity. Nat Immunol. 2010;11:1085-92 pubmed publisher

Luth E, Jun S, Wessen M, Liadaki K, Gussoni E, Kunkel L. Bone marrow side population cells are enriched for progenitors capable of myogenic differentiation. J Cell Sci. 2008;121:1426-34 pubmed publisher

Cho H, Lee N, Lee J, Choi Y, Ii M, Wecker A, et al. Role of host tissues for sustained humoral effects after endothelial progenitor cell transplantation into the ischemic heart. J Exp Med. 2007;204:3257-69 pubmed

Iwakoshi N, Pypaert M, Glimcher L. The transcription factor XBP-1 is essential for the development and survival of dendritic cells. J Exp Med. 2007;204:2267-75 pubmed

Leung C, Xu Y, Mularski B, Liu H, Gurbuxani S, Crispino J. Requirements for survivin in terminal differentiation of erythroid cells and maintenance of hematopoietic stem and progenitor cells. J Exp Med. 2007;204:1603-11 pubmed

Karlsson G, Blank U, Moody J, Ehinger M, Singbrant S, Deng C, et al. Smad4 is critical for self-renewal of hematopoietic stem cells. J Exp Med. 2007;204:467-74 pubmed

Krueger A, Garbe A, von Boehmer H. Phenotypic plasticity of T cell progenitors upon exposure to Notch ligands. J Exp Med. 2006;203:1977-84 pubmed

Blery M, Tze L, Miosge L, Jun J, Goodnow C. Essential role of membrane cholesterol in accelerated BCR internalization and uncoupling from NF-kappa B in B cell clonal anergy. J Exp Med. 2006;203:1773-83 pubmed

You H, Pellegrini M, Tsuchihara K, Yamamoto K, Hacker G, Erlacher M, et al. FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal. J Exp Med. 2006;203:1657-63 pubmed

Yamada Y, Takakura N. Physiological pathway of differentiation of hematopoietic stem cell population into mural cells. J Exp Med. 2006;203:1055-65 pubmed

Matsushita H, Scaglioni P, Bhaumik M, Rego E, Cai L, Majid S, et al. In vivo analysis of the role of aberrant histone deacetylase recruitment and RAR alpha blockade in the pathogenesis of acute promyelocytic leukemia. J Exp Med. 2006;203:821-8 pubmed

Ye M, Ermakova O, Graf T. PU.1 is not strictly required for B cell development and its absence induces a B-2 to B-1 cell switch. J Exp Med. 2005;202:1411-22 pubmed

Sacco A, Doyonnas R, Labarge M, Hammer M, Kraft P, Blau H. IGF-I increases bone marrow contribution to adult skeletal muscle and enhances the fusion of myelomonocytic precursors. J Cell Biol. 2005;171:483-92 pubmed

Tomita Y, Matsumura K, Wakamatsu Y, Matsuzaki Y, Shibuya I, Kawaguchi H, et al. Cardiac neural crest cells contribute to the dormant multipotent stem cell in the mammalian heart. J Cell Biol. 2005;170:1135-46 pubmed

Kato Y, Iwama A, Tadokoro Y, Shimoda K, Minoguchi M, Akira S, et al. Selective activation of STAT5 unveils its role in stem cell self-renewal in normal and leukemic hematopoiesis. J Exp Med. 2005;202:169-79 pubmed

Benz C, Bleul C. A multipotent precursor in the thymus maps to the branching point of the T versus B lineage decision. J Exp Med. 2005;202:21-31 pubmed

Ueda Y, Kondo M, Kelsoe G. Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow. J Exp Med. 2005;201:1771-80 pubmed

Stier S, Ko Y, Forkert R, Lutz C, Neuhaus T, Grünewald E, et al. Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size. J Exp Med. 2005;201:1781-91 pubmed

Dakic A, Metcalf D, Di Rago L, Mifsud S, Wu L, Nutt S. PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis. J Exp Med. 2005;201:1487-502 pubmed

Gautier G, Humbert M, Deauvieau F, Scuiller M, Hiscott J, Bates E, et al. A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells. J Exp Med. 2005;201:1435-46 pubmed

Mandal M, Borowski C, Palomero T, Ferrando A, Oberdoerffer P, Meng F, et al. The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival. J Exp Med. 2005;201:603-14 pubmed

Nutt S, Metcalf D, D Amico A, Polli M, Wu L. Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors. J Exp Med. 2005;201:221-31 pubmed

Ling K, Ottersbach K, van Hamburg J, Oziemlak A, Tsai F, Orkin S, et al. GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells. J Exp Med. 2004;200:871-82 pubmed

Seet C, Brumbaugh R, Kee B. Early B cell factor promotes B lymphopoiesis with reduced interleukin 7 responsiveness in the absence of E2A. J Exp Med. 2004;199:1689-700 pubmed

Lee K, McNerney M, Stepp S, Mathew P, Schatzle J, Bennett M, et al. 2B4 acts as a non-major histocompatibility complex binding inhibitory receptor on mouse natural killer cells. J Exp Med. 2004;199:1245-54 pubmed

Schmidt U, van den Akker E, Parren van Amelsvoort M, Litos G, de Bruijn M, Gutierrez L, et al. Btk is required for an efficient response to erythropoietin and for SCF-controlled protection against TRAIL in erythroid progenitors. J Exp Med. 2004;199:785-95 pubmed

Shibayama H, Takai E, Matsumura I, Kouno M, Morii E, Kitamura Y, et al. Identification of a cytokine-induced antiapoptotic molecule anamorsin essential for definitive hematopoiesis. J Exp Med. 2004;199:581-92 pubmed

Okada H, Bakal C, Shahinian A, Elia A, Wakeham A, Suh W, et al. Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death. J Exp Med. 2004;199:399-410 pubmed

Langer J, Henckaerts E, Orenstein J, Snoeck H. Quantitative trait analysis reveals transforming growth factor-beta2 as a positive regulator of early hematopoietic progenitor and stem cell function. J Exp Med. 2004;199:5-14 pubmed

Santiago Raber M, Baccala R, Haraldsson K, Choubey D, Stewart T, Kono D, et al. Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice. J Exp Med. 2003;197:777-88 pubmed

Migliaccio A, Rana R, Sanchez M, Lorenzini R, Centurione L, Bianchi L, et al. GATA-1 as a regulator of mast cell differentiation revealed by the phenotype of the GATA-1low mouse mutant. J Exp Med. 2003;197:281-96 pubmed

Boonstra A, Asselin Paturel C, Gilliet M, Crain C, Trinchieri G, Liu Y, et al. Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligation. J Exp Med. 2003;197:101-9 pubmed

Kolbus A, Pilat S, Husak Z, Deiner E, Stengl G, Beug H, et al. Raf-1 antagonizes erythroid differentiation by restraining caspase activation. J Exp Med. 2002;196:1347-53 pubmed

Gugasyan R, Quilici C, I S, Grail D, Verhagen A, Roberts A, et al. Dok-related protein negatively regulates T cell development via its RasGTPase-activating protein and Nck docking sites. J Cell Biol. 2002;158:115-25 pubmed

Hirasawa R, Shimizu R, Takahashi S, Osawa M, Takayanagi S, Kato Y, et al. Essential and instructive roles of GATA factors in eosinophil development. J Exp Med. 2002;195:1379-86 pubmed

Ohta H, Sawada A, Kim J, Tokimasa S, Nishiguchi S, Humphries R, et al. Polycomb group gene rae28 is required for sustaining activity of hematopoietic stem cells. J Exp Med. 2002;195:759-70 pubmed

Suzuki A, Zheng Y, Kaneko S, Onodera M, Fukao K, Nakauchi H, et al. Clonal identification and characterization of self-renewing pluripotent stem cells in the developing liver. J Cell Biol. 2002;156:173-84 pubmed

Nakano H, Yanagita M, Gunn M. CD11c(+)B220(+)Gr-1(+) cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells. J Exp Med. 2001;194:1171-8 pubmed

Bryder D, Ramsfjell V, Dybedal I, Theilgaard Monch K, Högerkorp C, Adolfsson J, et al. Self-renewal of multipotent long-term repopulating hematopoietic stem cells is negatively regulated by Fas and tumor necrosis factor receptor activation. J Exp Med. 2001;194:941-52 pubmed

Ruiz Vela A, Serrano F, Gonzalez M, Abad J, Bernad A, Maki M, et al. Transplanted long-term cultured pre-BI cells expressing calpastatin are resistant to B cell receptor-induced apoptosis. J Exp Med. 2001;194:247-54 pubmed

Doyonnas R, Kershaw D, Duhme C, Merkens H, Chelliah S, Graf T, et al. Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin. J Exp Med. 2001;194:13-27 pubmed

Villunger A, O Reilly L, Holler N, Adams J, Strasser A. Fas ligand, Bcl-2, granulocyte colony-stimulating factor, and p38 mitogen-activated protein kinase: Regulators of distinct cell death and survival pathways in granulocytes. J Exp Med. 2000;192:647-58 pubmed

Nagaoka H, Takahashi Y, Hayashi R, Nakamura T, Ishii K, Matsuda J, et al. Ras mediates effector pathways responsible for pre-B cell survival, which is essential for the developmental progression to the late pre-B cell stage. J Exp Med. 2000;192:171-82 pubmed

Gress C, Jacenko O. Growth plate compressions and altered hematopoiesis in collagen X null mice. J Cell Biol. 2000;149:983-93 pubmed