product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
CD3
catalog :
561417
quantity :
25 Tests
price :
177.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
UCHT1
reactivity :
human, mouse, rhesus macaque
application :
immunocytochemistry, flow cytometry, immunohistochemistry - frozen section, blocking or activating experiments
more info or order :
citations: 165
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig s3a
Le Nours J, Gherardin N, Ramarathinam S, Awad W, Wiede F, Gully B, et al. A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1. Science. 2019;366:1522-1527 pubmed publisher
  • immunohistochemistry - frozen section; human; loading ...; fig 1b
Dang A, Teles R, Weiss D, Parvatiyar K, Sarno E, Ochoa M, et al. IL-26 contributes to host defense against intracellular bacteria. J Clin Invest. 2019;129:1926-1939 pubmed publisher
  • flow cytometry; human; loading ...; fig s1a
Remmerswaal E, Hombrink P, Nota B, Pircher H, ten Berge I, van Lier R, et al. Expression of IL-7Rα and KLRG1 defines functionally distinct CD8+ T-cell populations in humans. Eur J Immunol. 2019;49:694-708 pubmed publisher
  • flow cytometry; human; loading ...; fig s1a
Dias J, Boulouis C, Gorin J, van den Biggelaar R, Lal K, Gibbs A, et al. The CD4-CD8- MAIT cell subpopulation is a functionally distinct subset developmentally related to the main CD8+ MAIT cell pool. Proc Natl Acad Sci U S A. 2018;115:E11513-E11522 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a
Desimio M, Giuliani E, Ferraro A, Adorno G, Doria M. In Vitro Exposure to Prostratin but Not Bryostatin-1 Improves Natural Killer Cell Functions Including Killing of CD4+ T Cells Harboring Reactivated Human Immunodeficiency Virus. Front Immunol. 2018;9:1514 pubmed publisher
  • flow cytometry; human; loading ...; fig 6h, 6i
Jung I, Kim Y, Yu H, Lee M, Kim S, Lee J. CRISPR/Cas9-Mediated Knockout of DGK Improves Antitumor Activities of Human T Cells. Cancer Res. 2018;78:4692-4703 pubmed publisher
  • immunohistochemistry - frozen section; human; loading ...; fig 2a
  • flow cytometry; human; fig 1b
Sayin I, Radtke A, Vella L, Jin W, Wherry E, Buggert M, et al. Spatial distribution and function of T follicular regulatory cells in human lymph nodes. J Exp Med. 2018;215:1531-1542 pubmed publisher
  • flow cytometry; human; loading ...; fig 14
Messlinger H, Sebald H, Heger L, Dudziak D, Bogdan C, Schleicher U. Monocyte-Derived Signals Activate Human Natural Killer Cells in Response to Leishmania Parasites. Front Immunol. 2018;9:24 pubmed publisher
  • flow cytometry; human; fig 1a
Jeong J, Hong S, Kwon O, Ghang B, Hwang I, Kim Y, et al. CD14+ Cells with the Phenotype of Infiltrated Monocytes Consist of Distinct Populations Characterized by Anti-inflammatory as well as Pro-inflammatory Activity in Gouty Arthritis. Front Immunol. 2017;8:1260 pubmed publisher
  • flow cytometry; human; loading ...; fig s4a
Salio M, Gasser O, González López C, Martens A, Veerapen N, Gileadi U, et al. Activation of Human Mucosal-Associated Invariant T Cells Induces CD40L-Dependent Maturation of Monocyte-Derived and Primary Dendritic Cells. J Immunol. 2017;199:2631-2638 pubmed publisher
  • flow cytometry; human; loading ...; fig 5a
Gaggianesi M, Turdo A, Chinnici A, Lipari E, Apuzzo T, Benfante A, et al. IL4 Primes the Dynamics of Breast Cancer Progression via DUSP4 Inhibition. Cancer Res. 2017;77:3268-3279 pubmed publisher
  • flow cytometry; human; loading ...; tbl 2
van der Velden V, Flores Montero J, Perez Andres M, Martin Ayuso M, Crespo O, Blanco E, et al. Optimization and testing of dried antibody tube: The EuroFlow LST and PIDOT tubes as examples. J Immunol Methods. 2017;: pubmed publisher
  • flow cytometry; human; loading ...; fig 5
O CONNOR D, Clutterbuck E, Thompson A, Snape M, Ramasamy M, Kelly D, et al. High-dimensional assessment of B-cell responses to quadrivalent meningococcal conjugate and plain polysaccharide vaccine. Genome Med. 2017;9:11 pubmed publisher
  • flow cytometry; human; loading ...
Tauriainen J, Scharf L, Frederiksen J, Naji A, Ljunggren H, Sonnerborg A, et al. Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals. Sci Rep. 2017;7:40354 pubmed publisher
  • flow cytometry; human; 1:100; loading ...; fig 2a
Siegers G, Barreira C, Postovit L, Dekaban G. CD11d ?2 integrin expression on human NK, B, and ?? T cells. J Leukoc Biol. 2017;101:1029-1035 pubmed publisher
  • flow cytometry; human; loading ...; fig 6
Gabanti E, Bruno F, Scaramuzzi L, Mangione F, Zelini P, Gerna G, et al. Predictive value of human cytomegalovirus (HCMV) T-cell response in the control of HCMV infection by seropositive solid-organ transplant recipients according to different assays and stimuli. New Microbiol. 2016;39:247-258 pubmed
  • flow cytometry; human; loading ...
Wang Y, Ma C, Ling Y, Bousfiha A, Camcioglu Y, Jacquot S, et al. Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations. J Exp Med. 2016;213:2413-2435 pubmed
  • flow cytometry; human; loading ...; fig 1a
Wahid R, Fresnay S, Levine M, Sztein M. Cross-reactive multifunctional CD4+ T cell responses against Salmonella enterica serovars Typhi, Paratyphi A and Paratyphi B in humans following immunization with live oral typhoid vaccine Ty21a. Clin Immunol. 2016;173:87-95 pubmed publisher
  • flow cytometry; human; loading ...; fig 2e
Paquin Proulx D, Gibbs A, Bachle S, Checa A, Introini A, Leeansyah E, et al. Innate Invariant NKT Cell Recognition of HIV-1-Infected Dendritic Cells Is an Early Detection Mechanism Targeted by Viral Immune Evasion. J Immunol. 2016;197:1843-51 pubmed publisher
  • flow cytometry; human; fig s3
van der Heiden M, van Zelm M, Bartol S, de Rond L, Berbers G, Boots A, et al. Differential effects of Cytomegalovirus carriage on the immune phenotype of middle-aged males and females. Sci Rep. 2016;6:26892 pubmed publisher
  • flow cytometry; human; loading ...; fig 5e
Loyon R, Picard E, Mauvais O, Queiroz L, Mougey V, Pallandre J, et al. IL-21-Induced MHC Class II+ NK Cells Promote the Expansion of Human Uncommitted CD4+ Central Memory T Cells in a Macrophage Migration Inhibitory Factor-Dependent Manner. J Immunol. 2016;197:85-96 pubmed publisher
  • flow cytometry; human; fig s1a
Yamashita K, Kawata K, Matsumiya H, Kamekura R, Jitsukawa S, Nagaya T, et al. Bob1 limits cellular frequency of T-follicular helper cells. Eur J Immunol. 2016;46:1361-70 pubmed publisher
  • flow cytometry; human; fig 4
Komori M, Lin Y, Cortese I, Blake A, Ohayon J, Cherup J, et al. Insufficient disease inhibition by intrathecal rituximab in progressive multiple sclerosis. Ann Clin Transl Neurol. 2016;3:166-79 pubmed publisher
  • flow cytometry; human; loading ...
Garcia Bates T, Kim E, Concha Benavente F, Trivedi S, Mailliard R, Gambotto A, et al. Enhanced Cytotoxic CD8 T Cell Priming Using Dendritic Cell-Expressing Human Papillomavirus-16 E6/E7-p16INK4 Fusion Protein with Sequenced Anti-Programmed Death-1. J Immunol. 2016;196:2870-8 pubmed publisher
  • blocking or activating experiments; human; 1 ug/ml; loading ...
Cao Y, Amezquita R, Kleinstein S, Stathopoulos P, Nowak R, O Connor K. Autoreactive T Cells from Patients with Myasthenia Gravis Are Characterized by Elevated IL-17, IFN-γ, and GM-CSF and Diminished IL-10 Production. J Immunol. 2016;196:2075-84 pubmed publisher
  • flow cytometry; human; fig 1
Deisting W, Raum T, Kufer P, Baeuerle P, Münz M. Impact of Diverse Immune Evasion Mechanisms of Cancer Cells on T Cells Engaged by EpCAM/CD3-Bispecific Antibody Construct AMG 110. PLoS ONE. 2015;10:e0141669 pubmed publisher
  • flow cytometry; human; fig 1
Leeansyah E, Svärd J, Dias J, Buggert M, Nyström J, Quigley M, et al. Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection. PLoS Pathog. 2015;11:e1005072 pubmed publisher
  • flow cytometry; human
Stenger E, Chiang K, Haight A, Qayed M, Kean L, Horan J. Use of Alefacept for Preconditioning in Multiply Transfused Pediatric Patients with Nonmalignant Diseases. Biol Blood Marrow Transplant. 2015;21:1845-52 pubmed publisher
  • flow cytometry; rhesus macaque
Soares A, Müller T, Chege G, Williamson A, Burgers W. Transient global T cell activation after vaccination of rhesus macaques with a DNA-poxvirus vaccine regimen for HIV. Vaccine. 2015;33:3435-9 pubmed publisher
  • flow cytometry; human; fig 4
McCully M, Collins P, Hughes T, Thomas C, Billen J, O Donnell V, et al. Skin Metabolites Define a New Paradigm in the Localization of Skin Tropic Memory T Cells. J Immunol. 2015;195:96-104 pubmed publisher
  • flow cytometry; human; loading ...; fig S1
DaFonseca S, Niessl J, Pouvreau S, Wacleche V, Gosselin A, Cleret Buhot A, et al. Impaired Th17 polarization of phenotypically naive CD4(+) T-cells during chronic HIV-1 infection and potential restoration with early ART. Retrovirology. 2015;12:38 pubmed publisher
  • flow cytometry; human
Zhou J, Amran F, Kramski M, Angelovich T, Elliott J, Hearps A, et al. An NK Cell Population Lacking FcRγ Is Expanded in Chronically Infected HIV Patients. J Immunol. 2015;194:4688-97 pubmed publisher
  • flow cytometry; human
Yukl S, Shergill A, Girling V, Li Q, Killian M, Epling L, et al. Site-specific differences in T cell frequencies and phenotypes in the blood and gut of HIV-uninfected and ART-treated HIV+ adults. PLoS ONE. 2015;10:e0121290 pubmed publisher
  • flow cytometry; human; fig 1e
Ohnuma K, Hatano R, Aune T, Otsuka H, Iwata S, Dang N, et al. Regulation of pulmonary graft-versus-host disease by IL-26+CD26+CD4 T lymphocytes. J Immunol. 2015;194:3697-712 pubmed publisher
  • flow cytometry; human
Strick Marchand H, Dusséaux M, Darche S, Huntington N, Legrand N, Masse Ranson G, et al. A novel mouse model for stable engraftment of a human immune system and human hepatocytes. PLoS ONE. 2015;10:e0119820 pubmed publisher
  • flow cytometry; human
Weihrauch M, Richly H, von Bergwelt Baildon M, Becker H, Schmidt M, Hacker U, et al. Phase I clinical study of the toll-like receptor 9 agonist MGN1703 in patients with metastatic solid tumours. Eur J Cancer. 2015;51:146-56 pubmed publisher
  • blocking or activating experiments; human; 1 ug/ml
Dominguez Villar M, Gautron A, de Marcken M, Keller M, Hafler D. TLR7 induces anergy in human CD4(+) T cells. Nat Immunol. 2015;16:118-28 pubmed publisher
  • flow cytometry; human
Thompson I, Mann E, Stokes M, English N, Knight S, Williamson D. Specific activation of dendritic cells enhances clearance of Bacillus anthracis following infection. PLoS ONE. 2014;9:e109720 pubmed publisher
  • flow cytometry; human
Luetke Eversloh M, Hammer Q, Durek P, Nordström K, Gasparoni G, Pink M, et al. Human cytomegalovirus drives epigenetic imprinting of the IFNG locus in NKG2Chi natural killer cells. PLoS Pathog. 2014;10:e1004441 pubmed publisher
  • flow cytometry; human
Spaan M, Kreefft K, de Graav G, Brouwer W, de Knegt R, ten Kate F, et al. CD4+ CXCR5+ T cells in chronic HCV infection produce less IL-21, yet are efficient at supporting B cell responses. J Hepatol. 2015;62:303-10 pubmed publisher
  • flow cytometry; human
  • immunocytochemistry; human
Yu C, Becker C, Metang P, Marches F, Wang Y, Toshiyuki H, et al. Human CD141+ dendritic cells induce CD4+ T cells to produce type 2 cytokines. J Immunol. 2014;193:4335-43 pubmed publisher
  • flow cytometry; human
Landy J, Al Hassi H, Ronde E, English N, Mann E, Bernardo D, et al. Innate immune factors in the development and maintenance of pouchitis. Inflamm Bowel Dis. 2014;20:1942-9 pubmed publisher
  • immunocytochemistry; mouse
Yu J, Zuo Z, Zhang W, Yang Q, Zhang Y, Tang Y, et al. Identification of immunophenotypic subtypes with different prognoses in extranodal natural killer/T-cell lymphoma, nasal type. Hum Pathol. 2014;45:2255-62 pubmed publisher
  • flow cytometry; human
Davey M, Morgan M, Liuzzi A, Tyler C, Khan M, Szakmany T, et al. Microbe-specific unconventional T cells induce human neutrophil differentiation into antigen cross-presenting cells. J Immunol. 2014;193:3704-3716 pubmed publisher
  • flow cytometry; human
Kreiser S, Eckhardt J, Kuhnt C, Stein M, Krzyzak L, Seitz C, et al. Murine CD83-positive T cells mediate suppressor functions in vitro and in vivo. Immunobiology. 2015;220:270-9 pubmed publisher
  • flow cytometry; human
Ohue Y, Kurose K, Mizote Y, Matsumoto H, Nishio Y, Isobe M, et al. Prolongation of overall survival in advanced lung adenocarcinoma patients with the XAGE1 (GAGED2a) antibody. Clin Cancer Res. 2014;20:5052-63 pubmed publisher
  • flow cytometry; human
Bending D, Pesenacker A, Ursu S, Wu Q, Lom H, Thirugnanabalan B, et al. Hypomethylation at the regulatory T cell-specific demethylated region in CD25hi T cells is decoupled from FOXP3 expression at the inflamed site in childhood arthritis. J Immunol. 2014;193:2699-708 pubmed publisher
  • flow cytometry; human; fig s1
Arlehamn C, Seumois G, Gerasimova A, Huang C, Fu Z, Yue X, et al. Transcriptional profile of tuberculosis antigen-specific T cells reveals novel multifunctional features. J Immunol. 2014;193:2931-40 pubmed publisher
  • flow cytometry; human
Laurent A, Bindslev N, Johansson B, Berg L. Synergistic effects of ethanol and isopentenyl pyrophosphate on expansion of ?? T cells in synovial fluid from patients with arthritis. PLoS ONE. 2014;9:e103683 pubmed publisher
  • flow cytometry; human
Lee Chang C, Bodogai M, Moritoh K, Olkhanud P, Chan A, Croft M, et al. Accumulation of 4-1BBL+ B cells in the elderly induces the generation of granzyme-B+ CD8+ T cells with potential antitumor activity. Blood. 2014;124:1450-9 pubmed publisher
  • flow cytometry; human
Kawasaki N, Rillahan C, Cheng T, Van Rhijn I, Macauley M, Moody D, et al. Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation. J Immunol. 2014;193:1560-6 pubmed publisher
  • flow cytometry; human
Barbosa R, Silva S, Silva S, Melo A, Pereira Santos M, Barata J, et al. Reduced BAFF-R and increased TACI expression in common variable immunodeficiency. J Clin Immunol. 2014;34:573-83 pubmed publisher
  • flow cytometry; human
Itoua Maïga R, Lemieux J, Roy A, Simard C, Néron S. Flow cytometry assessment of in vitro generated CD138+ human plasma cells. Biomed Res Int. 2014;2014:536482 pubmed publisher
  • flow cytometry; human; 1.6:100
Gros A, Robbins P, Yao X, Li Y, Turcotte S, Tran E, et al. PD-1 identifies the patient-specific CD8? tumor-reactive repertoire infiltrating human tumors. J Clin Invest. 2014;124:2246-59 pubmed publisher
  • flow cytometry; human
Prinz P, Mendler A, Brech D, Masouris I, Oberneder R, Noessner E. NK-cell dysfunction in human renal carcinoma reveals diacylglycerol kinase as key regulator and target for therapeutic intervention. Int J Cancer. 2014;135:1832-41 pubmed publisher
  • flow cytometry; human
Cairo C, Longinaker N, Cappelli G, Leke R, Ondo M, Djokam R, et al. Cord blood V?2V?2 T cells provide a molecular marker for the influence of pregnancy-associated malaria on neonatal immunity. J Infect Dis. 2014;209:1653-62 pubmed publisher
  • flow cytometry; human; loading ...
Krishnan S, Wilson E, Sheikh V, Rupert A, Mendoza D, Yang J, et al. Evidence for innate immune system activation in HIV type 1-infected elite controllers. J Infect Dis. 2014;209:931-9 pubmed publisher
  • flow cytometry; human
Li H, Pauza C. Critical roles for Akt kinase in controlling HIV envelope-mediated depletion of CD4 T cells. Retrovirology. 2013;10:60 pubmed publisher
  • flow cytometry; human
Melis L, Van Praet L, Pircher H, Venken K, Elewaut D. Senescence marker killer cell lectin-like receptor G1 (KLRG1) contributes to TNF-? production by interaction with its soluble E-cadherin ligand in chronically inflamed joints. Ann Rheum Dis. 2014;73:1223-31 pubmed publisher
Cogswell A, Maski K, Scammell T, Tucker D, Orban Z, Koralnik I. Children with Narcolepsy type 1 have increased T-cell responses to orexins. Ann Clin Transl Neurol. 2019;6:2566-2572 pubmed publisher
Canete P, Sweet R, Gonzalez Figueroa P, Papa I, Ohkura N, Bolton H, et al. Regulatory roles of IL-10-producing human follicular T cells. J Exp Med. 2019;: pubmed publisher
Baeuerle P, Ding J, Patel E, Thorausch N, Horton H, Gierut J, et al. Synthetic TRuC receptors engaging the complete T cell receptor for potent anti-tumor response. Nat Commun. 2019;10:2087 pubmed publisher
Hård J, Al Hakim E, Kindblom M, Björklund A, Sennblad B, Demirci I, et al. Conbase: a software for unsupervised discovery of clonal somatic mutations in single cells through read phasing. Genome Biol. 2019;20:68 pubmed publisher
Finney O, Brakke H, Rawlings Rhea S, Hicks R, Doolittle D, López M, et al. CD19 CAR T cell product and disease attributes predict leukemia remission durability. J Clin Invest. 2019;129:2123-2132 pubmed publisher
Heidt S, Vergunst M, Anholts J, Swings G, Gielis E, Groeneweg K, et al. Presence of intragraft B cells during acute renal allograft rejection is accompanied by changes in peripheral blood B cell subsets. Clin Exp Immunol. 2019;196:403-414 pubmed publisher
Yamamoto T, Lee P, Vodnala S, Gurusamy D, Kishton R, Yu Z, et al. T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy. J Clin Invest. 2019;129:1551-1565 pubmed publisher
Dollery S, Santiago Crespo R, Chatterjee D, Berger E. Glycoprotein K8.1A of Kaposi's Sarcoma-Associated Herpesvirus Is a Critical B Cell Tropism Determinant Independent of Its Heparan Sulfate Binding Activity. J Virol. 2019;93: pubmed publisher
Kimble J, Malherbe D, Meyer M, Gunn B, Karim M, Ilinykh P, et al. Antibody-Mediated Protective Mechanisms Induced by a Trivalent Parainfluenza Virus-Vectored Ebolavirus Vaccine. J Virol. 2019;93: pubmed publisher
Yurick D, Khoury G, Clemens B, Loh L, Pham H, Kedzierska K, et al. Multiplex Droplet Digital PCR Assay for Quantification of Human T-Cell Leukemia Virus Type 1 Subtype c DNA Proviral Load and T Cells from Blood and Respiratory Exudates Sampled in a Remote Setting. J Clin Microbiol. 2019;57: pubmed publisher
Kwaa A, Talana C, Blankson J. Interferon Alpha Enhances NK Cell Function and the Suppressive Capacity of HIV-Specific CD8+ T Cells. J Virol. 2019;93: pubmed publisher
Mulati K, Hamanishi J, Matsumura N, Chamoto K, Mise N, Abiko K, et al. VISTA expressed in tumour cells regulates T cell function. Br J Cancer. 2019;120:115-127 pubmed publisher
Anastasiadou E, Stroopinsky D, Alimperti S, Jiao A, Pyzer A, Cippitelli C, et al. Epstein-Barr virus-encoded EBNA2 alters immune checkpoint PD-L1 expression by downregulating miR-34a in B-cell lymphomas. Leukemia. 2019;33:132-147 pubmed publisher
Lajoie J, Tjernlund A, Omollo K, Edfeldt G, Röhl M, Boily Larouche G, et al. Increased cervical CD4+CCR5+ T cells among Kenyan sex working women using depot medroxyprogesterone acetate. AIDS Res Hum Retroviruses. 2018;: pubmed publisher
Kaszubowska L, Foerster J, Schetz D, Kmiec Z. CD56bright cells respond to stimulation until very advanced age revealing increased expression of cellular protective proteins SIRT1, HSP70 and SOD2. Immun Ageing. 2018;15:31 pubmed publisher
Egui A, Ledesma D, Pérez Antón E, Montoya A, Gómez I, Robledo S, et al. Phenotypic and Functional Profiles of Antigen-Specific CD4+ and CD8+ T Cells Associated With Infection Control in Patients With Cutaneous Leishmaniasis. Front Cell Infect Microbiol. 2018;8:393 pubmed publisher
He Z, Zhang J, Huang Z, Du Q, Li N, Zhang Q, et al. Sumoylation of RORγt regulates TH17 differentiation and thymocyte development. Nat Commun. 2018;9:4870 pubmed publisher
Petrillo C, Thorne L, Unali G, Schiroli G, Giordano A, Piras F, et al. Cyclosporine H Overcomes Innate Immune Restrictions to Improve Lentiviral Transduction and Gene Editing In Human Hematopoietic Stem Cells. Cell Stem Cell. 2018;23:820-832.e9 pubmed publisher
Acres M, Gothe F, Grainger A, Skelton A, Swan D, Willet J, et al. STAT5B deficiency due to a novel missense mutation in the coiled-coil domain. J Allergy Clin Immunol. 2018;: pubmed publisher
Richard A, Peters J, Savinykh N, Lee J, Hawley E, Meylan F, et al. Reduced monocyte and macrophage TNFSF15/TL1A expression is associated with susceptibility to inflammatory bowel disease. PLoS Genet. 2018;14:e1007458 pubmed publisher
Rosato R, Dávila González D, Choi D, Qian W, Chen W, Kozielski A, et al. Evaluation of anti-PD-1-based therapy against triple-negative breast cancer patient-derived xenograft tumors engrafted in humanized mouse models. Breast Cancer Res. 2018;20:108 pubmed publisher
Ilinykh P, Santos R, Gunn B, Kuzmina N, Shen X, Huang K, et al. Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and glycan cap. PLoS Pathog. 2018;14:e1007204 pubmed publisher
Smith C, Beckermann K, Bortone D, de Cubas A, Bixby L, Lee S, et al. Endogenous retroviral signatures predict immunotherapy response in clear cell renal cell carcinoma. J Clin Invest. 2018;128:4804-4820 pubmed publisher
Qi Z, Zhang Q, Liu B, Shao H, Li C. Early Changes in Circulatory T Helper Type 1, 2, and 17 Cells of Patients with Out-of-Hospital Cardiac Arrest after Successful Cardiopulmonary Resuscitation. Chin Med J (Engl). 2018;131:2071-2079 pubmed publisher
Sibener L, Fernandes R, Kolawole E, Carbone C, Liu F, McAffee D, et al. Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding. Cell. 2018;174:672-687.e27 pubmed publisher
Gilchuk P, Kuzmina N, Ilinykh P, Huang K, Gunn B, Bryan A, et al. Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein. Immunity. 2018;49:363-374.e10 pubmed publisher
Murakami T, Kim J, Li Y, Green G, Shikanov A, Ono A. Secondary lymphoid organ fibroblastic reticular cells mediate trans-infection of HIV-1 via CD44-hyaluronan interactions. Nat Commun. 2018;9:2436 pubmed publisher
Cornwell W, Kim V, Fan X, Vega M, Ramsey F, Criner G, et al. Activation and polarization of circulating monocytes in severe chronic obstructive pulmonary disease. BMC Pulm Med. 2018;18:101 pubmed publisher
Veneziani I, Brandetti E, Ognibene M, Pezzolo A, Pistoia V, Cifaldi L. Neuroblastoma Cell Lines Are Refractory to Genotoxic Drug-Mediated Induction of Ligands for NK Cell-Activating Receptors. J Immunol Res. 2018;2018:4972410 pubmed publisher
Le Roy A, Prebet T, Castellano R, Goubard A, Riccardi F, Fauriat C, et al. Immunomodulatory Drugs Exert Anti-Leukemia Effects in Acute Myeloid Leukemia by Direct and Immunostimulatory Activities. Front Immunol. 2018;9:977 pubmed publisher
Rezaei S, Lu H, Chang J, Rhodes A, Lewin S, Cameron P. The Pathway To Establishing HIV Latency Is Critical to How Latency Is Maintained and Reversed. J Virol. 2018;92: pubmed publisher
Keller B, Shoukier M, Schulz K, Bhatt A, Heine I, Strohmeier V, et al. Germline deletion of CIN85 in humans with X chromosome-linked antibody deficiency. J Exp Med. 2018;215:1327-1336 pubmed publisher
Kebir H, Carmant L, Fontaine F, Beland K, Bosoi C, Sanon N, et al. Humanized mouse model of Rasmussen's encephalitis supports the immune-mediated hypothesis. J Clin Invest. 2018;128:2000-2009 pubmed publisher
Guittard G, Dios Esponera A, Palmer D, Akpan I, Barr V, Manna A, et al. The Cish SH2 domain is essential for PLC-γ1 regulation in TCR stimulated CD8+ T cells. Sci Rep. 2018;8:5336 pubmed publisher
Correnti C, Laszlo G, de van der Schueren W, Godwin C, Bandaranayake A, Busch M, et al. Simultaneous multiple interaction T-cell engaging (SMITE) bispecific antibodies overcome bispecific T-cell engager (BiTE) resistance via CD28 co-stimulation. Leukemia. 2018;32:1239-1243 pubmed publisher
Tamosiuniene R, Manouvakhova O, Mésange P, Saito T, Qian J, Sanyal M, et al. Dominant Role for Regulatory T Cells in Protecting Females Against Pulmonary Hypertension. Circ Res. 2018;122:1689-1702 pubmed publisher
Chen C, Koenig A, Saison C, Dahdal S, Rigault G, Barba T, et al. CD4+ T Cell Help Is Mandatory for Naive and Memory Donor-Specific Antibody Responses: Impact of Therapeutic Immunosuppression. Front Immunol. 2018;9:275 pubmed publisher
Chitre A, Kattah M, Rosli Y, Pao M, Deswal M, Deeks S, et al. A20 upregulation during treated HIV disease is associated with intestinal epithelial cell recovery and function. PLoS Pathog. 2018;14:e1006806 pubmed publisher
Wagstaffe H, Nielsen C, Riley E, Goodier M. IL-15 Promotes Polyfunctional NK Cell Responses to Influenza by Boosting IL-12 Production. J Immunol. 2018;200:2738-2747 pubmed publisher
Hain A, Krämer M, Linka R, Nakhaei Rad S, Ahmadian M, Häussinger D, et al. IL-2 Inducible Kinase ITK is Critical for HIV-1 Infection of Jurkat T-cells. Sci Rep. 2018;8:3217 pubmed publisher
Laksono B, Grosserichter Wagener C, de Vries R, Langeveld S, Brem M, van Dongen J, et al. In Vitro Measles Virus Infection of Human Lymphocyte Subsets Demonstrates High Susceptibility and Permissiveness of both Naive and Memory B Cells. J Virol. 2018;92: pubmed publisher
Otta D, de Araújo F, de Rezende V, Souza Fagundes E, Eloi Santos S, Costa Silva M, et al. Identification of Anti-Trypanosoma cruzi Lead Compounds with Putative Immunomodulatory Activity. Antimicrob Agents Chemother. 2018;62: pubmed publisher
Blum L, Cao R, Sweatt A, Bill M, Lahey L, Hsi A, et al. Circulating plasmablasts are elevated and produce pathogenic anti-endothelial cell autoantibodies in idiopathic pulmonary arterial hypertension. Eur J Immunol. 2018;48:874-884 pubmed publisher
Vo L, Kinney M, Liu X, Zhang Y, Barragan J, Sousa P, et al. Regulation of embryonic haematopoietic multipotency by EZH1. Nature. 2018;553:506-510 pubmed publisher
Magalhaes I, Kalland I, Kochenderfer J, Osterborg A, Uhlin M, Mattsson J. CD19 Chimeric Antigen Receptor T Cells From Patients With Chronic Lymphocytic Leukemia Display an Elevated IFN-γ Production Profile. J Immunother. 2018;41:73-83 pubmed publisher
Mouloungui E, Zver T, Roux C, Amiot C. A protocol to isolate and qualify purified human preantral follicles in cases of acute leukemia, for future clinical applications. J Ovarian Res. 2018;11:4 pubmed publisher
Fan Y, Howden A, Sarhan A, Lis P, Ito G, Martinez T, et al. Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils. Biochem J. 2018;475:23-44 pubmed publisher
Bogaert D, Kuehn H, Bonroy C, Calvo K, Dehoorne J, Vanlander A, et al. A novel IKAROS haploinsufficiency kindred with unexpectedly late and variable B-cell maturation defects. J Allergy Clin Immunol. 2018;141:432-435.e7 pubmed publisher
Scherer E, Smith R, Carter J, Wipf G, Gallego D, Stern M, et al. Analysis of memory B cell responses reveals suboptimal dosing schedule of a licensed vaccine. J Infect Dis. 2017;: pubmed publisher
Molgora M, Bonavita E, Ponzetta A, Riva F, Barbagallo M, Jaillon S, et al. IL-1R8 is a checkpoint in NK cells regulating anti-tumour and anti-viral activity. Nature. 2017;551:110-114 pubmed publisher
Younan P, Iampietro M, Nishida A, Ramanathan P, Santos R, Dutta M, et al. Ebola Virus Binding to Tim-1 on T Lymphocytes Induces a Cytokine Storm. MBio. 2017;8: pubmed publisher
Gov L, Schneider C, Lima T, Pandori W, Lodoen M. NLRP3 and Potassium Efflux Drive Rapid IL-1β Release from Primary Human Monocytes during Toxoplasma gondii Infection. J Immunol. 2017;199:2855-2864 pubmed publisher
Sharma N, Trinidad C, Trembath A, Markiewicz M. NKG2D Signaling between Human NK Cells Enhances TACE-Mediated TNF-α Release. J Immunol. 2017;199:2865-2872 pubmed publisher
Magnani D, Silveira C, Ricciardi M, Gonzalez Nieto L, Pedreño Lopez N, Bailey V, et al. Potent Plasmablast-Derived Antibodies Elicited by the National Institutes of Health Dengue Vaccine. J Virol. 2017;91: pubmed publisher
Jiménez Sánchez A, Memon D, Pourpe S, Veeraraghavan H, Li Y, Vargas H, et al. Heterogeneous Tumor-Immune Microenvironments among Differentially Growing Metastases in an Ovarian Cancer Patient. Cell. 2017;170:927-938.e20 pubmed publisher
Ogunjimi B, Zhang S, Sørensen K, Skipper K, Carter Timofte M, Kerner G, et al. Inborn errors in RNA polymerase III underlie severe varicella zoster virus infections. J Clin Invest. 2017;127:3543-3556 pubmed publisher
Day C, Abrahams D, Harris L, van Rooyen M, Stone L, de Kock M, et al. HIV-1 Infection Is Associated with Depletion and Functional Impairment of Mycobacterium tuberculosis-Specific CD4 T Cells in Individuals with Latent Tuberculosis Infection. J Immunol. 2017;199:2069-2080 pubmed publisher
Schwerd T, Twigg S, Aschenbrenner D, Manrique S, Miller K, Taylor I, et al. A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis. J Exp Med. 2017;214:2547-2562 pubmed publisher
Gorvel L, Korenfeld D, Tung T, Klechevsky E. Dendritic Cell-Derived IL-32?: A Novel Inhibitory Cytokine of NK Cell Function. J Immunol. 2017;199:1290-1300 pubmed publisher
Papa I, Saliba D, Ponzoni M, Bustamante S, Canete P, Gonzalez Figueroa P, et al. TFH-derived dopamine accelerates productive synapses in germinal centres. Nature. 2017;547:318-323 pubmed publisher
Sulzer D, Alcalay R, Garretti F, Cote L, Kanter E, Agin Liebes J, et al. T cells from patients with Parkinson's disease recognize α-synuclein peptides. Nature. 2017;546:656-661 pubmed publisher
van Nierop G, van Luijn M, Michels S, Melief M, Janssen M, Langerak A, et al. Phenotypic and functional characterization of T cells in white matter lesions of multiple sclerosis patients. Acta Neuropathol. 2017;134:383-401 pubmed publisher
McDonnell A, Cook A, Robinson B, Lake R, Nowak A. Serial immunomonitoring of cancer patients receiving combined antagonistic anti-CD40 and chemotherapy reveals consistent and cyclical modulation of T cell and dendritic cell parameters. BMC Cancer. 2017;17:417 pubmed publisher
Iampietro M, Younan P, Nishida A, Dutta M, Lubaki N, Santos R, et al. Ebola virus glycoprotein directly triggers T lymphocyte death despite of the lack of infection. PLoS Pathog. 2017;13:e1006397 pubmed publisher
Gay C, Bosch R, Ritz J, Hataye J, Aga E, Tressler R, et al. Clinical Trial of the Anti-PD-L1 Antibody BMS-936559 in HIV-1 Infected Participants on Suppressive Antiretroviral Therapy. J Infect Dis. 2017;215:1725-1733 pubmed publisher
Cottineau J, Kottemann M, Lach F, Kang Y, Vély F, Deenick E, et al. Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency. J Clin Invest. 2017;127:1991-2006 pubmed publisher
Darboe A, Danso E, Clarke E, Umesi A, Touray E, Wegmüller R, et al. Enhancement of cytokine-driven NK cell IFN-γ production after vaccination of HCMV infected Africans. Eur J Immunol. 2017;47:1040-1050 pubmed publisher
Bi X, Li F, Liu S, Jin Y, Zhang X, Yang T, et al. ?-3 polyunsaturated fatty acids ameliorate type 1 diabetes and autoimmunity. J Clin Invest. 2017;127:1757-1771 pubmed publisher
Breuning J, Brown M. T Cell Costimulation by CD6 Is Dependent on Bivalent Binding of a GADS/SLP-76 Complex. Mol Cell Biol. 2017;37: pubmed publisher
Franchi L, Monteleone I, Hao L, Spahr M, Zhao W, Liu X, et al. Inhibiting Oxidative Phosphorylation In Vivo Restrains Th17 Effector Responses and Ameliorates Murine Colitis. J Immunol. 2017;198:2735-2746 pubmed publisher
Chaturvedi A, Herbst L, Pusch S, Klett L, Goparaju R, Stichel D, et al. Pan-mutant-IDH1 inhibitor BAY1436032 is highly effective against human IDH1 mutant acute myeloid leukemia in vivo. Leukemia. 2017;31:2020-2028 pubmed publisher
Yin Q, Sivina M, Robins H, Yusko E, Vignali M, O Brien S, et al. Ibrutinib Therapy Increases T Cell Repertoire Diversity in Patients with Chronic Lymphocytic Leukemia. J Immunol. 2017;198:1740-1747 pubmed publisher
Moy R, Huffman A, Richman L, Crisalli L, Wang X, Hoxie J, et al. Clinical and immunologic impact of CCR5 blockade in graft-versus-host disease prophylaxis. Blood. 2017;129:906-916 pubmed publisher
Gieseler Halbach S, Meltendorf S, Pierau M, Weinert S, Heidel F, Fischer T, et al. RSK-mediated nuclear accumulation of the cold-shock Y-box protein-1 controls proliferation of T cells and T-ALL blasts. Cell Death Differ. 2017;24:371-383 pubmed publisher
Sierzega M, Lenart M, Rutkowska M, Surman M, Mytar B, Matyja A, et al. Preoperative Neutrophil-Lymphocyte and Lymphocyte-Monocyte Ratios Reflect Immune Cell Population Rearrangement in Resectable Pancreatic Cancer. Ann Surg Oncol. 2017;24:808-815 pubmed publisher
Yi J, Manna A, Barr V, Hong J, Neuman K, Samelson L. madSTORM: a superresolution technique for large-scale multiplexing at single-molecule accuracy. Mol Biol Cell. 2016;27:3591-3600 pubmed
Oh Y, Park H, Shin J, Lee J, Park H, Kho D, et al. Ndrg1 is a T-cell clonal anergy factor negatively regulated by CD28 costimulation and interleukin-2. Nat Commun. 2015;6:8698 pubmed publisher
Mazzeo C, Calvo V, Alonso R, Mérida I, Izquierdo M. Protein kinase D1/2 is involved in the maturation of multivesicular bodies and secretion of exosomes in T and B lymphocytes. Cell Death Differ. 2016;23:99-109 pubmed publisher
Anderson A, Pratt A, Sedhom M, Doran J, Routledge C, Hargreaves B, et al. IL-6-driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anticitrullinated peptide antibody-negative rheumatoid arthritis. Ann Rheum Dis. 2016;75:466-73 pubmed publisher
Reissfelder C, Stamova S, Gossmann C, Braun M, Bonertz A, Walliczek U, et al. Tumor-specific cytotoxic T lymphocyte activity determines colorectal cancer patient prognosis. J Clin Invest. 2015;125:739-51 pubmed publisher
Alcázar I, Marqués M, Kumar A, Hirsch E, Wymann M, Carrera A, et al. Phosphoinositide 3-kinase gamma participates in T cell receptor-induced T cell activation. J Exp Med. 2007;204:2977-87 pubmed
Asperti Boursin F, Real E, Bismuth G, Trautmann A, Donnadieu E. CCR7 ligands control basal T cell motility within lymph node slices in a phosphoinositide 3-kinase-independent manner. J Exp Med. 2007;204:1167-79 pubmed
Le Floc h A, Jalil A, Vergnon I, Le Maux Chansac B, Lazar V, Bismuth G, et al. Alpha E beta 7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis. J Exp Med. 2007;204:559-70 pubmed
Koguchi K, Anderson D, Yang L, O Connor K, Kuchroo V, Hafler D. Dysregulated T cell expression of TIM3 in multiple sclerosis. J Exp Med. 2006;203:1413-8 pubmed
Bryceson Y, March M, Barber D, Ljunggren H, Long E. Cytolytic granule polarization and degranulation controlled by different receptors in resting NK cells. J Exp Med. 2005;202:1001-12 pubmed
Feske S, Prakriya M, Rao A, Lewis R. A severe defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients. J Exp Med. 2005;202:651-62 pubmed
Myers M, Dragone L, Weiss A. Src-like adaptor protein down-regulates T cell receptor (TCR)-CD3 expression by targeting TCRzeta for degradation. J Cell Biol. 2005;170:285-94 pubmed
Mehandru S, Poles M, Tenner Racz K, Horowitz A, Hurley A, Hogan C, et al. Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract. J Exp Med. 2004;200:761-70 pubmed
Schaerli P, Ebert L, Willimann K, Blaser A, Roos R, Loetscher P, et al. A skin-selective homing mechanism for human immune surveillance T cells. J Exp Med. 2004;199:1265-75 pubmed
Metelitsa L, Wu H, Wang H, Yang Y, Warsi Z, Asgharzadeh S, et al. Natural killer T cells infiltrate neuroblastomas expressing the chemokine CCL2. J Exp Med. 2004;199:1213-21 pubmed
Viglietta V, Baecher Allan C, Weiner H, Hafler D. Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis. J Exp Med. 2004;199:971-9 pubmed
Luhder F, Huang Y, Dennehy K, Guntermann C, Muller I, Winkler E, et al. Topological requirements and signaling properties of T cell-activating, anti-CD28 antibody superagonists. J Exp Med. 2003;197:955-66 pubmed
Galli G, Nuti S, Tavarini S, Galli Stampino L, de Lalla C, Casorati G, et al. CD1d-restricted help to B cells by human invariant natural killer T lymphocytes. J Exp Med. 2003;197:1051-7 pubmed
Liu X, Adams A, Wildt K, Aronow B, Feigenbaum L, Bosselut R. Restricting Zap70 expression to CD4+CD8+ thymocytes reveals a T cell receptor-dependent proofreading mechanism controlling the completion of positive selection. J Exp Med. 2003;197:363-73 pubmed
Bunnell S, Hong D, Kardon J, Yamazaki T, McGlade C, Barr V, et al. T cell receptor ligation induces the formation of dynamically regulated signaling assemblies. J Cell Biol. 2002;158:1263-75 pubmed
Dieckmann D, Bruett C, Ploettner H, Lutz M, Schuler G. Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected]. J Exp Med. 2002;196:247-53 pubmed
Darlington P, Baroja M, Chau T, Siu E, Ling V, Carreno B, et al. Surface cytotoxic T lymphocyte-associated antigen 4 partitions within lipid rafts and relocates to the immunological synapse under conditions of inhibition of T cell activation. J Exp Med. 2002;195:1337-47 pubmed
Chen X, Laur O, Kambayashi T, Li S, Bray R, Weber D, et al. Regulated expression of human histocompatibility leukocyte antigen (HLA)-DO during antigen-dependent and antigen-independent phases of B cell development. J Exp Med. 2002;195:1053-62 pubmed
McGavin M, Badour K, Hardy L, Kubiseski T, Zhang J, Siminovitch K. The intersectin 2 adaptor links Wiskott Aldrich Syndrome protein (WASp)-mediated actin polymerization to T cell antigen receptor endocytosis. J Exp Med. 2001;194:1777-87 pubmed
Carlin L, Eleme K, McCann F, Davis D. Intercellular transfer and supramolecular organization of human leukocyte antigen C at inhibitory natural killer cell immune synapses. J Exp Med. 2001;194:1507-17 pubmed
Kim C, Rott L, Clark Lewis I, Campbell D, Wu L, Butcher E. Subspecialization of CXCR5+ T cells: B helper activity is focused in a germinal center-localized subset of CXCR5+ T cells. J Exp Med. 2001;193:1373-81 pubmed
Dieckmann D, Plottner H, Berchtold S, Berger T, Schuler G. Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood. J Exp Med. 2001;193:1303-10 pubmed
Jonuleit H, Schmitt E, Stassen M, Tuettenberg A, Knop J, Enk A. Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood. J Exp Med. 2001;193:1285-94 pubmed
Kirchgessner H, Dietrich J, Scherer J, Isomaki P, Korinek V, Hilgert I, et al. The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain. J Exp Med. 2001;193:1269-84 pubmed
Freeman G, Long A, Iwai Y, Bourque K, Chernova T, Nishimura H, et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med. 2000;192:1027-34 pubmed
Kunkel E, Campbell J, Haraldsen G, Pan J, Boisvert J, Roberts A, et al. Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity. J Exp Med. 2000;192:761-8 pubmed
product information
Cat.# :
561417
Brand :
BD Horizon
Name :
CD3
Format :
V500
Clone :
UCHT1
Isotype :
Ms IgG 1
React :
Hu
Apps :
FCM
Size :
25 Tests
Status :
RUO
List Price :
177.00 USD
more info or order :
company information