product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
HLA-DR
catalog :
561224
quantity :
100 Tests
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
G46-6
reactivity :
human, mouse, dogs, chimpanzee, rhesus macaque
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 50
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig s3b
Reis M, Willis G, Fernandez Gonzalez A, Yeung V, Taglauer E, Magaletta M, et al. Mesenchymal Stromal Cell-Derived Extracellular Vesicles Restore Thymic Architecture and T Cell Function Disrupted by Neonatal Hyperoxia. Front Immunol. 2021;12:640595 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a, 4b
Kim J, Jeong J, Jung J, Jeon H, Lee S, Lim J, et al. Immunological characteristics and possible pathogenic role of urinary CD11c+ macrophages in lupus nephritis. Rheumatology (Oxford). 2020;: pubmed publisher
  • flow cytometry; human; loading ...; fig s5c
Banga R, Rebecchini C, Procopio F, Noto A, Munoz O, Ioannidou K, et al. Lymph node migratory dendritic cells modulate HIV-1 transcription through PD-1 engagement. PLoS Pathog. 2019;15:e1007918 pubmed publisher
  • flow cytometry; mouse; loading ...
Veglia F, Tyurin V, Blasi M, De Leo A, Kossenkov A, Donthireddy L, et al. Fatty acid transport protein 2 reprograms neutrophils in cancer. Nature. 2019;569:73-78 pubmed publisher
  • flow cytometry; rhesus macaque; loading ...; fig 2d
Chea L, Wyatt L, Gangadhara S, Moss B, Amara R. Novel Modified Vaccinia Virus Ankara Vector Expressing Anti-apoptotic Gene B13R Delays Apoptosis and Enhances Humoral Responses. J Virol. 2019;93: pubmed publisher
  • flow cytometry; human; loading ...; fig 5c
Resheq Y, Menzner A, Bosch J, Tickle J, Li K, Wilhelm A, et al. Impaired Transmigration of Myeloid-Derived Suppressor Cells across Human Sinusoidal Endothelium Is Associated with Decreased Expression of CD13. J Immunol. 2017;199:1672-1681 pubmed publisher
  • flow cytometry; human; loading ...; fig S1a
Wouters K, Gaens K, Bijnen M, Verboven K, Jocken J, Wetzels S, et al. Circulating classical monocytes are associated with CD11c+ macrophages in human visceral adipose tissue. Sci Rep. 2017;7:42665 pubmed publisher
  • flow cytometry; human; loading ...; fig s2
Su S, Zou Z, Chen F, Ding N, Du J, Shao J, et al. CRISPR-Cas9-mediated disruption of PD-1 on human T cells for adoptive cellular therapies of EBV positive gastric cancer. Oncoimmunology. 2017;6:e1249558 pubmed publisher
  • flow cytometry; human; loading ...; fig 6e
Tauriainen J, Scharf L, Frederiksen J, Naji A, Ljunggren H, Sonnerborg A, et al. Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals. Sci Rep. 2017;7:40354 pubmed publisher
  • flow cytometry; human; loading ...; fig 3a
Faivre V, Lukaszewicz A, Payen D. Downregulation of Blood Monocyte HLA-DR in ICU Patients Is Also Present in Bone Marrow Cells. PLoS ONE. 2016;11:e0164489 pubmed publisher
  • flow cytometry; human; loading ...; tbl s2
Snyder Mackler N, Sanz J, Kohn J, Brinkworth J, Morrow S, Shaver A, et al. Social status alters immune regulation and response to infection in macaques. Science. 2016;354:1041-1045 pubmed
  • flow cytometry; human; loading ...; tbl 3
Casamayor Genescà A, Pla A, Oliver Vila I, Pujals Fonts N, Marín Gallén S, Caminal M, et al. Clinical-scale expansion of CD34+ cord blood cells amplifies committed progenitors and rapid scid repopulation cells. N Biotechnol. 2017;35:19-29 pubmed publisher
  • flow cytometry; human
van Haren S, Dowling D, Foppen W, Christensen D, Andersen P, Reed S, et al. Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization. J Immunol. 2016;197:4413-4424 pubmed
  • flow cytometry; human; loading ...; fig 4b
Komdeur F, Wouters M, Workel H, Tijans A, Terwindt A, Brunekreeft K, et al. CD103+ intraepithelial T cells in high-grade serous ovarian cancer are phenotypically diverse TCRαβ+ CD8αβ+ T cells that can be targeted for cancer immunotherapy. Oncotarget. 2016;7:75130-75144 pubmed publisher
  • flow cytometry; human; loading ...; fig 2a
Cheng W, van Asten S, Burns L, Evans H, Walter G, Hashim A, et al. Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses. Eur J Immunol. 2016;46:2211-21 pubmed publisher
  • flow cytometry; human; fig 1
Domingues R, de Carvalho G, Aoki V, da Silva Duarte A, Sato M. Activation of myeloid dendritic cells, effector cells and regulatory T cells in lichen planus. J Transl Med. 2016;14:171 pubmed publisher
  • flow cytometry; human; 1:200; loading ...; fig 7j
Göbel K, Pankratz S, Asaridou C, Herrmann A, Bittner S, Merker M, et al. Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells. Nat Commun. 2016;7:11626 pubmed publisher
  • flow cytometry; human; 1:100; fig 5
Cook A, McDonnell A, Lake R, Nowak A. Dexamethasone co-medication in cancer patients undergoing chemotherapy causes substantial immunomodulatory effects with implications for chemo-immunotherapy strategies. Oncoimmunology. 2016;5:e1066062 pubmed
  • flow cytometry; human; loading ...; fig 7a
Qualai J, Li L, Cantero J, Tarrats A, Fernández M, Sumoy L, et al. Expression of CD11c Is Associated with Unconventional Activated T Cell Subsets with High Migratory Potential. PLoS ONE. 2016;11:e0154253 pubmed publisher
  • flow cytometry; human; 1:40; fig 2
Johnson D, Estrada M, Salgado R, Sanchez V, Doxie D, Opalenik S, et al. Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy. Nat Commun. 2016;7:10582 pubmed publisher
  • flow cytometry; human; fig 5
Su S, Hu B, Shao J, Shen B, Du J, Du Y, et al. CRISPR-Cas9 mediated efficient PD-1 disruption on human primary T cells from cancer patients. Sci Rep. 2016;6:20070 pubmed publisher
  • flow cytometry; human; fig S1A
Waschbisch A, Schröder S, Schraudner D, Sammet L, Weksler B, Melms A, et al. Pivotal Role for CD16+ Monocytes in Immune Surveillance of the Central Nervous System. J Immunol. 2016;196:1558-67 pubmed publisher
  • flow cytometry; human; loading ...; fig s3
Li R, Rezk A, Miyazaki Y, Hilgenberg E, Touil H, Shen P, et al. Proinflammatory GM-CSF-producing B cells in multiple sclerosis and B cell depletion therapy. Sci Transl Med. 2015;7:310ra166 pubmed publisher
  • flow cytometry; human; loading ...; fig 2i
Schulz A, Mälzer J, Domingo C, Jürchott K, Grützkau A, Babel N, et al. Low Thymic Activity and Dendritic Cell Numbers Are Associated with the Immune Response to Primary Viral Infection in Elderly Humans. J Immunol. 2015;195:4699-711 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2d
Okoye Okafor U, Bartholdy B, Cartier J, Gao E, Pietrak B, Rendina A, et al. New IDH1 mutant inhibitors for treatment of acute myeloid leukemia. Nat Chem Biol. 2015;11:878-86 pubmed publisher
  • flow cytometry; human; fig 2
Ducret M, Fabre H, Farges J, Degoul O, Atzeni G, McGuckin C, et al. Production of Human Dental Pulp Cells with a Medicinal Manufacturing Approach. J Endod. 2015;41:1492-9 pubmed publisher
  • flow cytometry; human
Metcalf Pate K, Pohlmeyer C, Walker Sperling V, Foote J, Najarro K, Cryer C, et al. A Murine Viral Outgrowth Assay to Detect Residual HIV Type 1 in Patients With Undetectable Viral Loads. J Infect Dis. 2015;212:1387-96 pubmed publisher
  • flow cytometry; human; fig 2
  • immunocytochemistry; human; fig 1
Skogberg G, Lundberg V, Berglund M, Gudmundsdottir J, Telemo E, Lindgren S, et al. Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens. Immunol Cell Biol. 2015;93:727-34 pubmed publisher
  • flow cytometry; human; tbl s1
Claiborne D, Prince J, Scully E, Macharia G, Micci L, Lawson B, et al. Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4+ T cells, and disease progression. Proc Natl Acad Sci U S A. 2015;112:E1480-9 pubmed publisher
  • flow cytometry; human; fig 3
Lee J, Breton G, Oliveira T, Zhou Y, Aljoufi A, PUHR S, et al. Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow. J Exp Med. 2015;212:385-99 pubmed publisher
  • flow cytometry; human; fig 2
Rissiek A, Baumann I, Cuapio A, Mautner A, Kolster M, Arck P, et al. The expression of CD39 on regulatory T cells is genetically driven and further upregulated at sites of inflammation. J Autoimmun. 2015;58:12-20 pubmed publisher
  • flow cytometry; human
Johnson P, Challis R, Chowdhury F, Gao Y, Harvey M, Geldart T, et al. Clinical and biological effects of an agonist anti-CD40 antibody: a Cancer Research UK phase I study. Clin Cancer Res. 2015;21:1321-8 pubmed publisher
  • flow cytometry; human
Heninger A, Wentrup S, Al Saeedi M, Schiessling S, Giese T, Wartha F, et al. Immunomodulation of human intestinal T cells by the synthetic CD80 antagonist RhuDex®. Immun Inflamm Dis. 2014;2:166-80 pubmed publisher
  • flow cytometry; human
Thompson I, Mann E, Stokes M, English N, Knight S, Williamson D. Specific activation of dendritic cells enhances clearance of Bacillus anthracis following infection. PLoS ONE. 2014;9:e109720 pubmed publisher
  • flow cytometry; human; fig 2
Milne P, Bigley V, Gunawan M, Haniffa M, Collin M. CD1c+ blood dendritic cells have Langerhans cell potential. Blood. 2015;125:470-3 pubmed publisher
  • flow cytometry; human; fig 4
Fernandez C, Amarasena T, Kelleher A, Rossjohn J, McCluskey J, Godfrey D, et al. MAIT cells are depleted early but retain functional cytokine expression in HIV infection. Immunol Cell Biol. 2015;93:177-88 pubmed publisher
  • flow cytometry; human
Freeman A, Bridge J, Maruthayanar P, Overgaard N, Jung J, Simpson F, et al. Comparative immune phenotypic analysis of cutaneous Squamous Cell Carcinoma and Intraepidermal Carcinoma in immune-competent individuals: proportional representation of CD8+ T-cells but not FoxP3+ Regulatory T-cells is associated with disease stage. PLoS ONE. 2014;9:e110928 pubmed publisher
  • flow cytometry; human
O Regan N, Steinfelder S, Venugopal G, Rao G, Lucius R, Srikantam A, et al. Brugia malayi microfilariae induce a regulatory monocyte/macrophage phenotype that suppresses innate and adaptive immune responses. PLoS Negl Trop Dis. 2014;8:e3206 pubmed publisher
  • flow cytometry; human
Pritchard A, White O, Burel J, Carroll M, Phipps S, Upham J. Asthma is associated with multiple alterations in anti-viral innate signalling pathways. PLoS ONE. 2014;9:e106501 pubmed publisher
  • flow cytometry; human
Agrawal R, Wisniewski J, Yu M, Kennedy J, Platts Mills T, Heymann P, et al. Infection with human rhinovirus 16 promotes enhanced IgE responsiveness in basophils of atopic asthmatics. Clin Exp Allergy. 2014;44:1266-73 pubmed publisher
  • flow cytometry; human
Lee Chang C, Bodogai M, Moritoh K, Olkhanud P, Chan A, Croft M, et al. Accumulation of 4-1BBL+ B cells in the elderly induces the generation of granzyme-B+ CD8+ T cells with potential antitumor activity. Blood. 2014;124:1450-9 pubmed publisher
  • flow cytometry; human
Buggert M, Norstr m M, Salemi M, Hecht F, Karlsson A. Functional avidity and IL-2/perforin production is linked to the emergence of mutations within HLA-B*5701-restricted epitopes and HIV-1 disease progression. J Immunol. 2014;192:4685-96 pubmed publisher
  • flow cytometry; chimpanzee
Hodara V, Parodi L, Chavez D, Smith L, Lanford R, Giavedoni L. Characterization of ??T cells in naïve and HIV-infected chimpanzees and their responses to T-cell activators in vitro. J Med Primatol. 2014;43:258-71 pubmed publisher
  • flow cytometry; human
Søndergaard J, Vinner L, Brix S. Natural mannosylation of HIV-1 gp120 imposes no immunoregulatory effects in primary human plasmacytoid dendritic cells. Mol Immunol. 2014;59:180-7 pubmed publisher
  • flow cytometry; human; loading ...; fig 4B
Narita T, Ishida T, Masaki A, Suzuki S, Ito A, Mori F, et al. HTLV-1 bZIP factor-specific CD4 T cell responses in adult T cell leukemia/lymphoma patients after allogeneic hematopoietic stem cell transplantation. J Immunol. 2014;192:940-7 pubmed publisher
  • flow cytometry; human; 1:5
Sölder E, Böckle B, Nguyen V, Fürhapter C, Obexer P, Erdel M, et al. Isolation and characterization of CD133+CD34+VEGFR-2+CD45- fetal endothelial cells from human term placenta. Microvasc Res. 2012;84:65-73 pubmed publisher
Kogler G, Sensken S, Airey J, Trapp T, MUSCHEN M, Feldhahn N, et al. A new human somatic stem cell from placental cord blood with intrinsic pluripotent differentiation potential. J Exp Med. 2004;200:123-35 pubmed
Schaerli P, Ebert L, Willimann K, Blaser A, Roos R, Loetscher P, et al. A skin-selective homing mechanism for human immune surveillance T cells. J Exp Med. 2004;199:1265-75 pubmed
Dieckmann D, Bruett C, Ploettner H, Lutz M, Schuler G. Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected]. J Exp Med. 2002;196:247-53 pubmed
Dieckmann D, Plottner H, Berchtold S, Berger T, Schuler G. Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood. J Exp Med. 2001;193:1303-10 pubmed
product information
Cat.# :
561224
Brand :
BD Horizon
Name :
HLA-DR
Format :
V500
Clone :
G46-6
Isotype :
Ms IgG 2a
React :
Hu
Apps :
FCM
Size :
100 Tests
Status :
RUO
more info or order :
company information