product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
CD27
catalog :
561222
quantity :
100 Tests
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
M-T271
reactivity :
African green monkey, human, rhesus macaque
application :
flow cytometry
more info or order :
citations: 59
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig s2a
Reijm S, Kissel T, Stoeken Rijsbergen G, Slot L, Wortel C, van Dooren H, et al. Cross-reactivity of IgM anti-modified protein antibodies in rheumatoid arthritis despite limited mutational load. Arthritis Res Ther. 2021;23:230 pubmed publisher
  • flow cytometry; human; loading ...
Bohannon C, Ende Z, Cao W, Mboko W, Ranjan P, Kumar A, et al. Influenza Virus Infects and Depletes Activated Adaptive Immune Responders. Adv Sci (Weinh). 2021;8:e2100693 pubmed publisher
  • flow cytometry; human; 1:200; loading ...; fig s2a
Biswas S, Mandal G, Payne K, Anadon C, Gatenbee C, Chaurio R, et al. IgA transcytosis and antigen recognition govern ovarian cancer immunity. Nature. 2021;591:464-470 pubmed publisher
  • flow cytometry; human; loading ...; fig 2
Armas González E, Domínguez Luis M, Díaz Martín A, Arce Franco M, Castro Hernandez J, Danelon G, et al. Role of CXCL13 and CCL20 in the recruitment of B cells to inflammatory foci in chronic arthritis. Arthritis Res Ther. 2018;20:114 pubmed publisher
  • flow cytometry; human; loading ...; fig 4a
Han S, Yang S, Jo H, Oh Y, Park M, Kim J, et al. BAFF and APRIL expression as an autoimmune signature of membranous nephropathy. Oncotarget. 2018;9:3292-3302 pubmed publisher
  • flow cytometry; human; loading ...; fig 2
Hutten T, Norde W, Woestenenk R, Wang R, Maas F, Kester M, et al. Increased Coexpression of PD-1, TIGIT, and KLRG-1 on Tumor-Reactive CD8+ T Cells During Relapse after Allogeneic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2018;24:666-677 pubmed publisher
  • flow cytometry; human; loading ...; fig st1
Cerboni S, Jeremiah N, Gentili M, Gehrmann U, Conrad C, Stolzenberg M, et al. Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes. J Exp Med. 2017;214:1769-1785 pubmed publisher
  • flow cytometry; rhesus macaque; loading ...; fig s16b
Dowling D, van Haren S, Scheid A, Bergelson I, Kim D, Mancuso C, et al. TLR7/8 adjuvant overcomes newborn hyporesponsiveness to pneumococcal conjugate vaccine at birth. JCI Insight. 2017;2:e91020 pubmed publisher
  • flow cytometry; human; loading ...; fig s3a
Martin Gayo E, Cronin J, Hickman T, Ouyang Z, Lindqvist M, Kolb K, et al. Circulating CXCR5+CXCR3+PD-1lo Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth. JCI Insight. 2017;2:e89574 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a, s2f
Oon S, Huynh H, Tai T, Ng M, Monaghan K, Biondo M, et al. A cytotoxic anti-IL-3Rα antibody targets key cells and cytokines implicated in systemic lupus erythematosus. JCI Insight. 2016;1:e86131 pubmed publisher
  • flow cytometry; human; loading ...; fig 5
Toro J, Salgado D, Vega R, Rodríguez J, Rodríguez L, Angel J, et al. Total and Envelope Protein-Specific Antibody-Secreting Cell Response in Pediatric Dengue Is Highly Modulated by Age and Subsequent Infections. PLoS ONE. 2016;11:e0161795 pubmed publisher
  • flow cytometry; human; loading ...; fig 3a
Schade H, Sen S, Neff C, Freed B, Gao D, Gutman J, et al. Programmed Death 1 Expression on CD4+ T Cells Predicts Mortality after Allogeneic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2016;22:2172-2179 pubmed publisher
  • flow cytometry; human; loading ...; fig s2d
Xu Y, Chaudhury A, Zhang M, Savoldo B, Metelitsa L, Rodgers J, et al. Glycolysis determines dichotomous regulation of T cell subsets in hypoxia. J Clin Invest. 2016;126:2678-88 pubmed publisher
  • flow cytometry; African green monkey; loading ...; fig 2b
Neumann B, Shi T, Gan L, Klippert A, Daskalaki M, Stolte Leeb N, et al. Comprehensive panel of cross-reacting monoclonal antibodies for analysis of different immune cells and their distribution in the common marmoset (Callithrix jacchus). J Med Primatol. 2016;45:139-46 pubmed publisher
  • flow cytometry; human; fig 2
Yu C, Liu Y, Chan J, Tong J, Li Z, Shi M, et al. Identification of human plasma cells with a lamprey monoclonal antibody. JCI Insight. 2016;1: pubmed
  • flow cytometry; human; loading ...; fig s2
Yamashita K, Kawata K, Matsumiya H, Kamekura R, Jitsukawa S, Nagaya T, et al. Bob1 limits cellular frequency of T-follicular helper cells. Eur J Immunol. 2016;46:1361-70 pubmed publisher
  • flow cytometry; human; fig 1
Simon S, Vignard V, Florenceau L, Dreno B, Khammari A, Lang F, et al. PD-1 expression conditions T cell avidity within an antigen-specific repertoire. Oncoimmunology. 2016;5:e1104448 pubmed
  • flow cytometry; human; loading ...
Jabara H, Boyden S, Chou J, Ramesh N, Massaad M, Benson H, et al. A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency. Nat Genet. 2016;48:74-8 pubmed publisher
  • flow cytometry; human; loading ...; fig 3a
Campi Azevedo A, Costa Pereira C, Antonelli L, Fonseca C, Teixeira Carvalho A, Villela Rezende G, et al. Booster dose after 10 years is recommended following 17DD-YF primary vaccination. Hum Vaccin Immunother. 2016;12:491-502 pubmed publisher
  • flow cytometry; human; fig 3a
Chen X, Li W, Zhang Y, Song X, Xu L, Xu Z, et al. Distribution of Peripheral Memory T Follicular Helper Cells in Patients with Schistosomiasis Japonica. PLoS Negl Trop Dis. 2015;9:e0004015 pubmed publisher
  • flow cytometry; human; tbl s1
Weinberg A, Muresan P, Richardson K, Fenton T, Domínguez T, Bloom A, et al. Determinants of vaccine immunogenicity in HIV-infected pregnant women: analysis of B and T cell responses to pandemic H1N1 monovalent vaccine. PLoS ONE. 2015;10:e0122431 pubmed publisher
  • flow cytometry; human; tbl s1
Claiborne D, Prince J, Scully E, Macharia G, Micci L, Lawson B, et al. Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4+ T cells, and disease progression. Proc Natl Acad Sci U S A. 2015;112:E1480-9 pubmed publisher
  • flow cytometry; human; tbl s5
Dimova T, Brouwer M, Gosselin F, Tassignon J, Leo O, Donner C, et al. Effector Vγ9Vδ2 T cells dominate the human fetal γδ T-cell repertoire. Proc Natl Acad Sci U S A. 2015;112:E556-65 pubmed publisher
  • flow cytometry; human
Weihrauch M, Richly H, von Bergwelt Baildon M, Becker H, Schmidt M, Hacker U, et al. Phase I clinical study of the toll-like receptor 9 agonist MGN1703 in patients with metastatic solid tumours. Eur J Cancer. 2015;51:146-56 pubmed publisher
  • flow cytometry; human
Willmann K, Klaver S, DoÄŸu F, Santos Valente E, Garncarz W, Bilic I, et al. Biallelic loss-of-function mutation in NIK causes a primary immunodeficiency with multifaceted aberrant lymphoid immunity. Nat Commun. 2014;5:5360 pubmed publisher
  • flow cytometry; rhesus macaque
Neumann B, Klippert A, Raue K, Sopper S, Stahl Hennig C. Characterization of B and plasma cells in blood, bone marrow, and secondary lymphoid organs of rhesus macaques by multicolor flow cytometry. J Leukoc Biol. 2015;97:19-30 pubmed publisher
  • flow cytometry; human
Davey M, Morgan M, Liuzzi A, Tyler C, Khan M, Szakmany T, et al. Microbe-specific unconventional T cells induce human neutrophil differentiation into antigen cross-presenting cells. J Immunol. 2014;193:3704-3716 pubmed publisher
Brouwer P, Brinkkemper M, Maisonnasse P, Dereuddre Bosquet N, Grobben M, Claireaux M, et al. Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection. Cell. 2021;184:1188-1200.e19 pubmed publisher
Tanno H, McDaniel J, Stevens C, Voss W, Li J, Durrett R, et al. A facile technology for the high-throughput sequencing of the paired VH:VL and TCRβ:TCRα repertoires. Sci Adv. 2020;6:eaay9093 pubmed publisher
Farmer J, Allard Chamard H, Sun N, Ahmad M, Bertocchi A, Mahajan V, et al. Induction of metabolic quiescence defines the transitional to follicular B cell switch. Sci Signal. 2019;12: pubmed publisher
Serwas N, Hoeger B, Ardy R, Stulz S, Sui Z, Memaran N, et al. Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis. Nat Commun. 2019;10:3106 pubmed publisher
Yamamoto T, Lee P, Vodnala S, Gurusamy D, Kishton R, Yu Z, et al. T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy. J Clin Invest. 2019;129:1551-1565 pubmed publisher
Stephenson S, Care M, Fan I, Zougman A, Westhead D, Doody G, et al. Growth Factor-like Gene Regulation Is Separable from Survival and Maturation in Antibody-Secreting Cells. J Immunol. 2019;202:1287-1300 pubmed publisher
Embers M, Krishnavajhala A, Armstrong B, Curtis M, Pahar B, Wilder H, et al. Immunological Responses to the Relapsing Fever Spirochete Borrelia turicatae in Infected Rhesus Macaques: Implications for Pathogenesis and Diagnosis. Infect Immun. 2019;87: pubmed publisher
Luo Z, Ogunrinde E, Li M, Zhang L, Martin L, Zhou Z, et al. Increased influenza-specific antibody avidity in HIV-infected women compared with HIV-infected men on antiretroviral therapy. AIDS. 2019;33:33-44 pubmed publisher
Egui A, Ledesma D, Pérez Antón E, Montoya A, Gómez I, Robledo S, et al. Phenotypic and Functional Profiles of Antigen-Specific CD4+ and CD8+ T Cells Associated With Infection Control in Patients With Cutaneous Leishmaniasis. Front Cell Infect Microbiol. 2018;8:393 pubmed publisher
Kong X, Martinez Barricarte R, Kennedy J, Mele F, Lazarov T, Deenick E, et al. Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency. Nat Immunol. 2018;19:973-985 pubmed publisher
Laksono B, Grosserichter Wagener C, de Vries R, Langeveld S, Brem M, van Dongen J, et al. In Vitro Measles Virus Infection of Human Lymphocyte Subsets Demonstrates High Susceptibility and Permissiveness of both Naive and Memory B Cells. J Virol. 2018;92: pubmed publisher
Tsuda B, Miyamoto A, Yokoyama K, Ogiya R, Oshitanai R, Terao M, et al. B-cell populations are expanded in breast cancer patients compared with healthy controls. Breast Cancer. 2018;25:284-291 pubmed publisher
Scherer E, Smith R, Carter J, Wipf G, Gallego D, Stern M, et al. Analysis of memory B cell responses reveals suboptimal dosing schedule of a licensed vaccine. J Infect Dis. 2017;: pubmed publisher
Scally S, Murugan R, Bosch A, Triller G, Costa G, Mordmuller B, et al. Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection. J Exp Med. 2018;215:63-75 pubmed publisher
Wasiuk A, Testa J, Weidlick J, Sisson C, Vitale L, Widger J, et al. CD27-Mediated Regulatory T Cell Depletion and Effector T Cell Costimulation Both Contribute to Antitumor Efficacy. J Immunol. 2017;199:4110-4123 pubmed publisher
Luo Z, Zhou Z, Ogunrinde E, Zhang T, Li Z, Martin L, et al. The effect of plasma auto-IgGs on CD4+ T cell apoptosis and recovery in HIV-infected patients under antiretroviral therapy. J Leukoc Biol. 2017;102:1481-1486 pubmed publisher
Callender L, Carroll E, Beal R, Chambers E, Nourshargh S, Akbar A, et al. Human CD8+ EMRA T cells display a senescence-associated secretory phenotype regulated by p38 MAPK. Aging Cell. 2017;: pubmed publisher
Bogaert D, Kuehn H, Bonroy C, Calvo K, Dehoorne J, Vanlander A, et al. A novel IKAROS haploinsufficiency kindred with unexpectedly late and variable B-cell maturation defects. J Allergy Clin Immunol. 2018;141:432-435.e7 pubmed publisher
Ramos C, Ballard B, Zhang H, Dakhova O, Gee A, Mei Z, et al. Clinical and immunological responses after CD30-specific chimeric antigen receptor-redirected lymphocytes. J Clin Invest. 2017;127:3462-3471 pubmed publisher
Papa I, Saliba D, Ponzoni M, Bustamante S, Canete P, Gonzalez Figueroa P, et al. TFH-derived dopamine accelerates productive synapses in germinal centres. Nature. 2017;547:318-323 pubmed publisher
van Nierop G, van Luijn M, Michels S, Melief M, Janssen M, Langerak A, et al. Phenotypic and functional characterization of T cells in white matter lesions of multiple sclerosis patients. Acta Neuropathol. 2017;134:383-401 pubmed publisher
Zhao X, Howell K, He S, Brannan J, Wec A, Davidson E, et al. Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability. Cell. 2017;169:891-904.e15 pubmed publisher
Arumugakani G, Stephenson S, Newton D, Rawstron A, Emery P, Doody G, et al. Early Emergence of CD19-Negative Human Antibody-Secreting Cells at the Plasmablast to Plasma Cell Transition. J Immunol. 2017;198:4618-4628 pubmed publisher
Moy R, Huffman A, Richman L, Crisalli L, Wang X, Hoxie J, et al. Clinical and immunologic impact of CCR5 blockade in graft-versus-host disease prophylaxis. Blood. 2017;129:906-916 pubmed publisher
van Andel H, Ren Z, Koopmans I, Joosten S, Kocemba K, de Lau W, et al. Aberrantly expressed LGR4 empowers Wnt signaling in multiple myeloma by hijacking osteoblast-derived R-spondins. Proc Natl Acad Sci U S A. 2017;114:376-381 pubmed publisher
Baldan V, Griffiths R, Hawkins R, Gilham D. Efficient and reproducible generation of tumour-infiltrating lymphocytes for renal cell carcinoma. Br J Cancer. 2015;112:1510-8 pubmed publisher
Mateus J, Lasso P, Pavia P, Rosas F, Roa N, Valencia Hernández C, et al. Low frequency of circulating CD8+ T stem cell memory cells in chronic chagasic patients with severe forms of the disease. PLoS Negl Trop Dis. 2015;9:e3432 pubmed publisher
Schaerli P, Ebert L, Willimann K, Blaser A, Roos R, Loetscher P, et al. A skin-selective homing mechanism for human immune surveillance T cells. J Exp Med. 2004;199:1265-75 pubmed
Dieli F, Poccia F, Lipp M, Sireci G, Caccamo N, Di Sano C, et al. Differentiation of effector/memory Vdelta2 T cells and migratory routes in lymph nodes or inflammatory sites. J Exp Med. 2003;198:391-7 pubmed
Kruetzmann S, Rosado M, Weber H, Germing U, Tournilhac O, Peter H, et al. Human immunoglobulin M memory B cells controlling Streptococcus pneumoniae infections are generated in the spleen. J Exp Med. 2003;197:939-45 pubmed
Reignat S, Webster G, Brown D, Ogg G, King A, Seneviratne S, et al. Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus infection. J Exp Med. 2002;195:1089-101 pubmed
Kim C, Rott L, Clark Lewis I, Campbell D, Wu L, Butcher E. Subspecialization of CXCR5+ T cells: B helper activity is focused in a germinal center-localized subset of CXCR5+ T cells. J Exp Med. 2001;193:1373-81 pubmed
product information
Cat.# :
561222
Brand :
BD Horizon
Name :
CD27
Format :
V500
Clone :
M-T271
Isotype :
Ms IgG 1
React :
Hu
Apps :
FCM
Size :
100 Tests
Status :
RUO
more info or order :
company information