product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
CD11b
catalog :
561098
quantity :
25 µg
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
M1/70
reactivity :
human, mouse
application :
immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section, other
more info or order :
citations: 37
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...
Chi R, Yao C, Chen S, Liu Y, He Y, Zhang J, et al. Elevated BCAA Suppresses the Development and Metastasis of Breast Cancer. Front Oncol. 2022;12:887257 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4a
Puntambekar S, Moutinho M, Lin P, Jadhav V, Tumbleson Brink D, Balaji A, et al. CX3CR1 deficiency aggravates amyloid driven neuronal pathology and cognitive decline in Alzheimer's disease. Mol Neurodegener. 2022;17:47 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig s6h
Xiong W, Gao X, Zhang T, Jiang B, Hu M, Bu X, et al. USP8 inhibition reshapes an inflamed tumor microenvironment that potentiates the immunotherapy. Nat Commun. 2022;13:1700 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1g, s1h, s5f
Liu M, Wu C, Luo S, Hua Q, Chen H, Weng Y, et al. PERK reprograms hematopoietic progenitor cells to direct tumor-promoting myelopoiesis in the spleen. J Exp Med. 2022;219: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 3c
  • flow cytometry; mouse; loading ...; fig 3b
Chuang H, Chen M, Chen Y, Yang H, Ciou Y, Hsueh C, et al. BPI overexpression suppresses Treg differentiation and induces exosome-mediated inflammation in systemic lupus erythematosus. Theranostics. 2021;11:9953-9966 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s4b
Zhang Y, McGrath K, Ayoub E, Kingsley P, Yu H, Fegan K, et al. Mds1CreERT2, an inducible Cre allele specific to adult-repopulating hematopoietic stem cells. Cell Rep. 2021;36:109562 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5
Mathä L, Romera Hernandez M, Steer C, Yin Y, Orangi M, Shim H, et al. Migration of Lung Resident Group 2 Innate Lymphoid Cells Link Allergic Lung Inflammation and Liver Immunity. Front Immunol. 2021;12:679509 pubmed publisher
  • flow cytometry; mouse; loading ...; fig ds1a
Ortega Molina A, Lebrero Fernández C, Sanz A, Deleyto Seldas N, Plata Gómez A, Menéndez C, et al. Inhibition of Rag GTPase signaling in mice suppresses B cell responses and lymphomagenesis with minimal detrimental trade-offs. Cell Rep. 2021;36:109372 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 1b
McKinsey G, Lizama C, Keown Lang A, Niu A, Santander N, Larpthaveesarp A, et al. A new genetic strategy for targeting microglia in development and disease. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; 1:500; loading ...; fig 1s2
Madel M, Ibáñez L, Ciucci T, Halper J, Rouleau M, Boutin A, et al. Dissecting the phenotypic and functional heterogeneity of mouse inflammatory osteoclasts by the expression of Cx3cr1. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; 1:400; loading ...
Ortega Molina A, Deleyto Seldas N, Carreras J, Sanz A, Lebrero Fernández C, Menéndez C, et al. Oncogenic Rag GTPase signaling enhances B cell activation and drives follicular lymphoma sensitive to pharmacological inhibition of mTOR. Nat Metab. 2019;1:775-789 pubmed publisher
  • flow cytometry; mouse; 1:1600; loading ...; fig 4g
Jacome Galarza C, Percin G, Muller J, Mass E, Lazarov T, Eitler J, et al. Developmental origin, functional maintenance and genetic rescue of osteoclasts. Nature. 2019;568:541-545 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a
Mikolajczyk T, Nosalski R, Skiba D, Koziol J, Mazur M, Justo Junior A, et al. 1,2,3,4,6-Penta-O-galloyl-β-d-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension. Br J Pharmacol. 2019;176:1951-1965 pubmed publisher
  • flow cytometry; mouse; fig 2e
Cabron A, El Azzouzi K, Boss M, Arnold P, Schwarz J, Rosas M, et al. Structural and Functional Analyses of the Shedding Protease ADAM17 in HoxB8-Immortalized Macrophages and Dendritic-like Cells. J Immunol. 2018;201:3106-3118 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s5
Grist J, Marro B, Skinner D, Syage A, Worne C, Doty D, et al. Induced CNS expression of CXCL1 augments neurologic disease in a murine model of multiple sclerosis via enhanced neutrophil recruitment. Eur J Immunol. 2018;48:1199-1210 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2c
Supramaniam A, Liu X, Ferro V, Herrero L. Prophylactic Antiheparanase Activity by PG545 Is Antiviral In Vitro and Protects against Ross River Virus Disease in Mice. Antimicrob Agents Chemother. 2018;62: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4d
Garaycoechea J, Crossan G, Langevin F, Mulderrig L, Louzada S, Yang F, et al. Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. Nature. 2018;553:171-177 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s5
Stremmel C, Schuchert R, Wagner F, Thaler R, Weinberger T, Pick R, et al. Yolk sac macrophage progenitors traffic to the embryo during defined stages of development. Nat Commun. 2018;9:75 pubmed publisher
  • other; mouse; fig 5l
Tsai F, Homan P, Agrawal H, Misharin A, Abdala Valencia H, Haines G, et al. Bim suppresses the development of SLE by limiting myeloid inflammatory responses. J Exp Med. 2017;214:3753-3773 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4b
Ellman D, Degn M, Lund M, Clausen B, Novrup H, Flæng S, et al. Genetic Ablation of Soluble TNF Does Not Affect Lesion Size and Functional Recovery after Moderate Spinal Cord Injury in Mice. Mediators Inflamm. 2016;2016:2684098 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 1a
Zhao S, Yu Z, Liu Y, Bai Y, Jiang Y, van Leyen K, et al. CD47 deficiency improves neurological outcomes of traumatic brain injury in mice. Neurosci Lett. 2017;643:125-130 pubmed publisher
  • flow cytometry; mouse; loading ...
Thompson J, Hardin D, Glass J, Dziba J, Campion J, Brown S. The Inflammatory Cytokine IL-21 is Expressed by Splenic Neutrophils in Response to Transplantation of Allogeneic Cells. SOJ Immunol. 2016;4:1-9 pubmed
  • flow cytometry; mouse; fig 1c
Clausen B, Degn M, Sivasaravanaparan M, Fogtmann T, Andersen M, Trojanowsky M, et al. Conditional ablation of myeloid TNF increases lesion volume after experimental stroke in mice, possibly via altered ERK1/2 signaling. Sci Rep. 2016;6:29291 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 2g
Ruhland M, Loza A, Capietto A, Luo X, Knolhoff B, Flanagan K, et al. Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis. Nat Commun. 2016;7:11762 pubmed publisher
  • flow cytometry; mouse
Acharya M, Sokolovska A, Tam J, Conway K, Stefani C, Raso F, et al. αv Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells. Nat Commun. 2016;7:10917 pubmed publisher
  • flow cytometry; mouse; fig 2
Montufar Solis D, Klein J. Splenic Leukocytes Traffic to the Thyroid and Produce a Novel TSHβ Isoform during Acute Listeria monocytogenes Infection in Mice. PLoS ONE. 2016;11:e0146111 pubmed publisher
  • flow cytometry; mouse; tbl 1
Black L, Srivastava R, Schoeb T, Moore R, Barnes S, KABAROWSKI J. Cholesterol-Independent Suppression of Lymphocyte Activation, Autoimmunity, and Glomerulonephritis by Apolipoprotein A-I in Normocholesterolemic Lupus-Prone Mice. J Immunol. 2015;195:4685-98 pubmed publisher
  • flow cytometry; mouse; 1:100; fig s4
Mikucki M, Fisher D, Matsuzaki J, Skitzki J, Gaulin N, Muhitch J, et al. Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints. Nat Commun. 2015;6:7458 pubmed publisher
  • flow cytometry; mouse; loading ...; fig S3d
Steinckwich N, Myers P, Janardhan K, Flagler N, King D, Petranka J, et al. Role of the store-operated calcium entry protein, STIM1, in neutrophil chemotaxis and infiltration into a murine model of psoriasis-inflamed skin. FASEB J. 2015;29:3003-13 pubmed publisher
  • flow cytometry; mouse; fig s1f
Van Den Ham K, Shio M, Rainone A, Fournier S, Krawczyk C, Olivier M. Iron prevents the development of experimental cerebral malaria by attenuating CXCR3-mediated T cell chemotaxis. PLoS ONE. 2015;10:e0118451 pubmed publisher
  • flow cytometry; mouse; fig 4
Karsten C, Laumonnier Y, Eurich B, Ender F, Bröker K, Roy S, et al. Monitoring and cell-specific deletion of C5aR1 using a novel floxed GFP-C5aR1 reporter knock-in mouse. J Immunol. 2015;194:1841-55 pubmed publisher
  • flow cytometry; human
Freeman A, Bridge J, Maruthayanar P, Overgaard N, Jung J, Simpson F, et al. Comparative immune phenotypic analysis of cutaneous Squamous Cell Carcinoma and Intraepidermal Carcinoma in immune-competent individuals: proportional representation of CD8+ T-cells but not FoxP3+ Regulatory T-cells is associated with disease stage. PLoS ONE. 2014;9:e110928 pubmed publisher
  • flow cytometry; mouse
Parker K, Sinha P, Horn L, Clements V, Yang H, Li J, et al. HMGB1 enhances immune suppression by facilitating the differentiation and suppressive activity of myeloid-derived suppressor cells. Cancer Res. 2014;74:5723-33 pubmed publisher
  • flow cytometry; mouse
Grymula K, Tarnowski M, Piotrowska K, Suszynska M, Mierzejewska K, Borkowska S, et al. Evidence that the population of quiescent bone marrow-residing very small embryonic/epiblast-like stem cells (VSELs) expands in response to neurotoxic treatment. J Cell Mol Med. 2014;18:1797-806 pubmed publisher
  • flow cytometry; mouse
Syu L, El Zaatari M, Eaton K, Liu Z, Tetarbe M, Keeley T, et al. Transgenic expression of interferon-? in mouse stomach leads to inflammation, metaplasia, and dysplasia. Am J Pathol. 2012;181:2114-25 pubmed publisher
Meng J, Zou X, Wu R, Zhong R, Zhu D, Zhang Y. Accelerated regeneration of the skeletal muscle in RNF13-knockout mice is mediated by macrophage-secreted IL-4/IL-6. Protein Cell. 2014;5:235-47 pubmed publisher
El Zaatari M, Kao J, Tessier A, Bai L, Hayes M, Fontaine C, et al. Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets. PLoS ONE. 2013;8:e58935 pubmed publisher
product information
Cat.# :
561098
Brand :
BD Pharmingen
Name :
CD11b
Format :
PE-Cy™7
Clone :
M1/70
Isotype :
Rat IgG 2b
React :
Ms
Conc :
0.2 mg/ml
Apps :
FCM
Size :
25 µg
Status :
RUO
more info or order :
company information