product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Akt pS473
catalog :
560858
quantity :
50 Tests
price :
245.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
M89-61
reactivity :
human, mouse
application :
western blot, immunocytochemistry, flow cytometry
more info or order :
citations: 19
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 4a
  • western blot; human; loading ...; fig 5b
Fenwick C, Loredo Varela J, Joo V, Pellaton C, Farina A, Rajah N, et al. Tumor suppression of novel anti-PD-1 antibodies mediated through CD28 costimulatory pathway. J Exp Med. 2019;: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3e
Getahun A, Wemlinger S, Rudra P, Santiago M, van Dyk L, Cambier J. Impaired B cell function during viral infections due to PTEN-mediated inhibition of the PI3K pathway. J Exp Med. 2017;214:931-941 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5e
Vogel K, Bell L, Galloway A, Ahlfors H, Turner M. The RNA-Binding Proteins Zfp36l1 and Zfp36l2 Enforce the Thymic ?-Selection Checkpoint by Limiting DNA Damage Response Signaling and Cell Cycle Progression. J Immunol. 2016;197:2673-2685 pubmed publisher
  • flow cytometry; human; fig 2g
Muller Durovic B, Lanna A, Covre L, Mills R, Henson S, Akbar A. Killer Cell Lectin-like Receptor G1 Inhibits NK Cell Function through Activation of Adenosine 5'-Monophosphate-Activated Protein Kinase. J Immunol. 2016;197:2891-2899 pubmed publisher
  • flow cytometry; human; loading ...; fig 6b
Zwang N, Zhang R, Germana S, Fan M, Hastings W, Cao A, et al. Selective Sparing of Human Tregs by Pharmacologic Inhibitors of the Phosphatidylinositol 3-Kinase and MEK Pathways. Am J Transplant. 2016;16:2624-38 pubmed publisher
  • flow cytometry; human; fig 5
Rebbapragada I, Birkus G, Perry J, Xing W, Kwon H, Pflanz S. Molecular Determinants of GS-9620-Dependent TLR7 Activation. PLoS ONE. 2016;11:e0146835 pubmed publisher
  • flow cytometry; mouse; fig 7a
Tellier J, Shi W, Minnich M, Liao Y, Crawford S, Smyth G, et al. Blimp-1 controls plasma cell function through the regulation of immunoglobulin secretion and the unfolded protein response. Nat Immunol. 2016;17:323-30 pubmed publisher
  • flow cytometry; human
Setoguchi R, Matsui Y, Mouri K. mTOR signaling promotes a robust and continuous production of IFN-γ by human memory CD8+ T cells and their proliferation. Eur J Immunol. 2015;45:893-902 pubmed publisher
Labuhn M, Perkins K, Matzk S, Varghese L, Garnett C, Papaemmanuil E, et al. Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome. Cancer Cell. 2019;36:123-138.e10 pubmed publisher
Capitano M, Mor Vaknin N, Saha A, Cooper S, Legendre M, Guo H, et al. Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling. J Clin Invest. 2019;129:2555-2570 pubmed publisher
Kim C, Hu B, Jadhav R, Jin J, Zhang H, Cavanagh M, et al. Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells. Cell Rep. 2018;25:2148-2162.e5 pubmed publisher
Jensen I, Winborn C, Fosdick M, Shao P, Tremblay M, Shan Q, et al. Polymicrobial sepsis influences NK-cell-mediated immunity by diminishing NK-cell-intrinsic receptor-mediated effector responses to viral ligands or infections. PLoS Pathog. 2018;14:e1007405 pubmed publisher
Preite S, Cannons J, Radtke A, Vujkovic Cvijin I, Gomez Rodriguez J, Volpi S, et al. Hyperactivated PI3Kδ promotes self and commensal reactivity at the expense of optimal humoral immunity. Nat Immunol. 2018;19:986-1000 pubmed publisher
Agnihotri P, Robertson N, Umetsu S, Arakcheeva K, Winandy S. Lack of Ikaros cripples expression of Foxo1 and its targets in naive T cells. Immunology. 2017;152:494-506 pubmed publisher
Zhou H, Mak P, Mu H, Mak D, Zeng Z, Cortes J, et al. Combined inhibition of ?-catenin and Bcr-Abl synergistically targets tyrosine kinase inhibitor-resistant blast crisis chronic myeloid leukemia blasts and progenitors in vitro and in vivo. Leukemia. 2017;31:2065-2074 pubmed publisher
Ho C, Chhabra A, Starkl P, Schnorr P, Wilmes S, Moraga I, et al. Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling. Cell. 2017;168:1041-1052.e18 pubmed publisher
Pomeroy E, Lee L, Lee R, Schirm D, Temiz N, Ma J, et al. Ras oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS(V12) oncogene addiction in acute myeloid leukemia. Oncogene. 2017;36:3263-3273 pubmed publisher
Chen H, Händel N, Ngeow J, Muller J, Huhn M, Yang H, et al. Immune dysregulation in patients with PTEN hamartoma tumor syndrome: Analysis of FOXP3 regulatory T cells. J Allergy Clin Immunol. 2017;139:607-620.e15 pubmed publisher
Wang Y, Yang Y, You X, Deng X, Hu C, Zhu C, et al. Ex vivo nicotine stimulation augments the efficacy of human peripheral blood mononuclear cell-derived dendritic cell vaccination via activating Akt-S6 pathway. Anal Cell Pathol (Amst). 2015;2015:741487 pubmed publisher
product information
Cat.# :
560858
Brand :
BD Phosflow
Name :
Akt pS473
Format :
V450
Clone :
M89-61
Isotype :
Ms IgG 1
React :
Hu , Ms
Apps :
IC/FCM
Size :
50 Tests
Status :
RUO
List Price :
245.00 USD
more info or order :
company information