product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
IFN
catalog :
560661
quantity :
50 µg
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
XMG1.2
reactivity :
human, mouse
application :
western blot, ELISA, immunocytochemistry, flow cytometry, blocking or activating experiments
more info or order :
citations: 287
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; fig 5b
Zhu Y, Elsheikha H, Wang J, Fang S, He J, Zhu X, et al. Synergy between Toxoplasma gondii type I ΔGRA17 immunotherapy and PD-L1 checkpoint inhibition triggers the regression of targeted and distal tumors. J Immunother Cancer. 2021;9: pubmed publisher
  • flow cytometry; mouse; loading ...
Yang C, Kwon D, Kim M, Im S, Lee Y. Commensal Microbiome Expands Tγδ17 Cells in the Lung and Promotes Particulate Matter-Induced Acute Neutrophilia. Front Immunol. 2021;12:645741 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a, 3b
Horiuchi H, Parajuli B, Komiya H, Ogawa Y, Jin S, Takahashi K, et al. Interleukin-19 Abrogates Experimental Autoimmune Encephalomyelitis by Attenuating Antigen-Presenting Cell Activation. Front Immunol. 2021;12:615898 pubmed publisher
  • flow cytometry; mouse; fig 1c
Zhao L, Hu S, Davila M, Yang J, Lin Y, Albanese J, et al. Coordinated co-migration of CCR10+ antibody-producing B cells with helper T cells for colonic homeostatic regulation. Mucosal Immunol. 2021;14:420-430 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4b
Gibaldi D, Vilar Pereira G, Pereira I, Silva A, Barrios L, Ramos I, et al. CCL3/Macrophage Inflammatory Protein-1α Is Dually Involved in Parasite Persistence and Induction of a TNF- and IFNγ-Enriched Inflammatory Milieu in Trypanosoma cruzi-Induced Chronic Cardiomyopathy. Front Immunol. 2020;11:306 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1m
Choi S, Bae H, Jeong S, Park I, Cho H, Hong S, et al. YAP/TAZ direct commitment and maturation of lymph node fibroblastic reticular cells. Nat Commun. 2020;11:519 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1c
Thiele Née Schrewe L, Guse K, Tietz S, Remlinger J, Demir S, Pedreiturria X, et al. Functional relevance of the multi-drug transporter abcg2 on teriflunomide therapy in an animal model of multiple sclerosis. J Neuroinflammation. 2020;17:9 pubmed publisher
  • flow cytometry; mouse; fig 3c
Cheng M, Chen Y, Huang D, Chen W, Xu W, Chen Y, et al. Intrinsically altered lung-resident γδT cells control lung melanoma by producing interleukin-17A in the elderly. Aging Cell. 2020;19:e13099 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2d
Leone R, Zhao L, Englert J, Sun I, Oh M, Sun I, et al. Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion. Science. 2019;366:1013-1021 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2f
Chen Z, Ji Z, Ngiow S, Manne S, Cai Z, Huang A, et al. TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision. Immunity. 2019;51:840-855.e5 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3a
Sharma N, Vacher J, Allison J. TLR1/2 ligand enhances antitumor efficacy of CTLA-4 blockade by increasing intratumoral Treg depletion. Proc Natl Acad Sci U S A. 2019;116:10453-10462 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4b
Mikolajczyk T, Nosalski R, Skiba D, Koziol J, Mazur M, Justo Junior A, et al. 1,2,3,4,6-Penta-O-galloyl-β-d-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension. Br J Pharmacol. 2019;176:1951-1965 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5d
Ha D, Tanaka A, Kibayashi T, Tanemura A, Sugiyama D, Wing J, et al. Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti-CTLA-4 antibody. Proc Natl Acad Sci U S A. 2019;116:609-618 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1e
Qu J, Li L, Xie H, Zhang X, Yang Q, Qiu H, et al. TLR3 Modulates the Response of NK Cells against Schistosoma japonicum. J Immunol Res. 2018;2018:7519856 pubmed publisher
  • flow cytometry; mouse; 1:400; loading ...; fig s7a
Wang H, D Souza C, Lim X, Kostenko L, Pediongco T, Eckle S, et al. MAIT cells protect against pulmonary Legionella longbeachae infection. Nat Commun. 2018;9:3350 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig s3c
Zhao D, Kim Y, Jeong S, Greenson J, Chaudhry M, Hoepting M, et al. Survival signal REG3α prevents crypt apoptosis to control acute gastrointestinal graft-versus-host disease. J Clin Invest. 2018;128:4970-4979 pubmed publisher
  • flow cytometry; human; loading ...; fig 1d
Khan A, Srivastava R, Vahed H, Roy S, Walia S, Kim G, et al. Human Asymptomatic Epitope Peptide/CXCL10-Based Prime/Pull Vaccine Induces Herpes Simplex Virus-Specific Gamma Interferon-Positive CD107+ CD8+ T Cells That Infiltrate the Corneas and Trigeminal Ganglia of Humanized HLA Transgenic Rabbits and Protect . J Virol. 2018;92: pubmed publisher
  • flow cytometry; human; loading ...; fig 1d
Ludtmann M, Angelova P, Horrocks M, Choi M, Rodrigues M, Baev A, et al. α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson's disease. Nat Commun. 2018;9:2293 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s3g
Ma C, Han M, Heinrich B, Fu Q, Zhang Q, Sandhu M, et al. Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells. Science. 2018;360: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5a
Drobek A, Moudra A, Mueller D, Huranová M, Horková V, Pribikova M, et al. Strong homeostatic TCR signals induce formation of self-tolerant virtual memory CD8 T cells. EMBO J. 2018;37: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 7a
Dipiazza A, Laniewski N, Rattan A, Topham D, Miller J, Sant A. CD4 T Cell Epitope Specificity and Cytokine Potential Are Preserved as Cells Transition from the Lung Vasculature to Lung Tissue following Influenza Virus Infection. J Virol. 2018;92: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
Kling J, Jordan M, Pitt L, Meiners J, Thanh Tran T, Tran L, et al. Temporal Regulation of Natural Killer T Cell Interferon Gamma Responses by β-Catenin-Dependent and -Independent Wnt Signaling. Front Immunol. 2018;9:483 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5e
Xiao F, Ai G, Yan W, Wan X, Luo X, Ning Q. Intrahepatic recruitment of cytotoxic NK cells contributes to autoimmune hepatitis progression. Cell Immunol. 2018;327:13-20 pubmed publisher
  • flow cytometry; mouse; 1:50; loading ...; fig 7e
Mencarelli A, Khameneh H, Fric J, Vacca M, El Daker S, Janela B, et al. Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis. Nat Commun. 2018;9:1102 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5b
Westhorpe C, Norman M, Hall P, Snelgrove S, Finsterbusch M, Li A, et al. Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes. Nat Commun. 2018;9:747 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 2a
Guimarães G, Gomes M, Campos P, Marinho F, de Assis N, Silveira T, et al. Immunoproteasome Subunits Are Required for CD8+ T Cell Function and Host Resistance to Brucella abortus Infection in Mice. Infect Immun. 2018;86: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b
Maseda D, Johnson E, Nyhoff L, Baron B, Kojima F, Wilhelm A, et al. mPGES1-Dependent Prostaglandin E2 (PGE2) Controls Antigen-Specific Th17 and Th1 Responses by Regulating T Autocrine and Paracrine PGE2 Production. J Immunol. 2018;200:725-736 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1c
Whitney P, Makhlouf C, MacLeod B, Ma J, Gressier E, Greyer M, et al. Effective Priming of Herpes Simplex Virus-Specific CD8+ T Cells In Vivo Does Not Require Infected Dendritic Cells. J Virol. 2018;92: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s6b
Bouziat R, Hinterleitner R, Brown J, Stencel Baerenwald J, Ikizler M, Mayassi T, et al. Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease. Science. 2017;356:44-50 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 6b
Bhattacharyya M, Penaloza MacMaster P. T regulatory cells are critical for the maintenance, anamnestic expansion and protection elicited by vaccine-induced CD8 T cells. Immunology. 2017;151:340-348 pubmed publisher
  • flow cytometry; mouse; fig 4d
Baranek T, Morello E, Valayer A, Aimar R, Bréa D, Henry C, et al. FHL2 Regulates Natural Killer Cell Development and Activation during Streptococcus pneumoniae Infection. Front Immunol. 2017;8:123 pubmed publisher
  • flow cytometry; mouse; fig 6m
Knudson K, Pritzl C, Saxena V, Altman A, Daniels M, Teixeiro E. NFκB-Pim-1-Eomesodermin axis is critical for maintaining CD8 T-cell memory quality. Proc Natl Acad Sci U S A. 2017;114:E1659-E1667 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a
Pardi N, Hogan M, Pelc R, Muramatsu H, Andersen H, Demaso C, et al. Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination. Nature. 2017;543:248-251 pubmed publisher
  • flow cytometry; human; fig 7b
Welsby I, Detienne S, N kuli F, Thomas S, Wouters S, Bechtold V, et al. Lysosome-Dependent Activation of Human Dendritic Cells by the Vaccine Adjuvant QS-21. Front Immunol. 2016;7:663 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5e
Nowyhed H, Chandra S, Kiosses W, Marcovecchio P, Andary F, Zhao M, et al. ATP Binding Cassette Transporter ABCA7 Regulates NKT Cell Development and Function by Controlling CD1d Expression and Lipid Raft Content. Sci Rep. 2017;7:40273 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 4A
Troegeler A, Mercier I, Cougoule C, Pietretti D, Colom A, Duval C, et al. C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells. Proc Natl Acad Sci U S A. 2017;114:E540-E549 pubmed publisher
  • ELISA; mouse; loading ...; fig 3c
Rowe A, Yun H, Hendricks R. Exposure Stress Induces Reversible Corneal Graft Opacity in Recipients With Herpes Simplex Virus-1 Infections. Invest Ophthalmol Vis Sci. 2017;58:35-41 pubmed publisher
  • flow cytometry; mouse; 0.5 ug/ml; fig st4
van der Weyden L, Arends M, Campbell A, Bald T, Wardle Jones H, Griggs N, et al. Genome-wide in vivo screen identifies novel host regulators of metastatic colonization. Nature. 2017;541:233-236 pubmed publisher
  • blocking or activating experiments; mouse; loading ...
  • flow cytometry; mouse; loading ...
Hayakawa M, Hayakawa H, Petrova T, Ritprajak P, Sutavani R, Jiménez Andrade G, et al. Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction. J Biol Chem. 2017;292:1762-1772 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig s4a
Griffiths K, Ahmed M, Das S, Gopal R, Horne W, Connell T, et al. Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy. Nat Commun. 2016;7:13894 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 2e
Ohs I, Van Den Broek M, Nussbaum K, MUNZ C, Arnold S, Quezada S, et al. Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis. Nat Commun. 2016;7:13708 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3e
Sektioglu I, Carretero R, Bulbuc N, Bald T, Tüting T, Rudensky A, et al. Basophils Promote Tumor Rejection via Chemotaxis and Infiltration of CD8+ T Cells. Cancer Res. 2017;77:291-302 pubmed publisher
  • flow cytometry; human; loading ...; fig 4h
Srivastava R, Khan A, Garg S, Syed S, Furness J, Vahed H, et al. Human Asymptomatic Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP13/14 (UL47) Preferentially Recall Polyfunctional Effector Memory CD44high CD62Llow CD8+ TEM Cells and Protect Humanized HLA-A*02:01 Transgenic Mice against Ocula. J Virol. 2017;91: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4d
Park K, Mikulski Z, Seo G, Andreyev A, Marcovecchio P, Blatchley A, et al. The transcription factor NR4A3 controls CD103+ dendritic cell migration. J Clin Invest. 2016;126:4603-4615 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s6
Laurent C, Dorothee G, Hunot S, Martin E, Monnet Y, Duchamp M, et al. Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy. Brain. 2017;140:184-200 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 7c
Kwong Chung C, Ronchi F, Geuking M. Detrimental effect of systemic antimicrobial CD4+ T-cell reactivity on gut epithelial integrity. Immunology. 2017;150:221-235 pubmed publisher
  • flow cytometry; mouse; fig s3
Hrdinka M, Sudan K, Just S, Drobek A, Stepanek O, Schluter D, et al. Normal Development and Function of T Cells in Proline Rich 7 (Prr7) Deficient Mice. PLoS ONE. 2016;11:e0162863 pubmed publisher
  • blocking or activating experiments; mouse; 10 ug/ml; fig s6c
Lexmond W, Goettel J, Lyons J, Jacobse J, Deken M, Lawrence M, et al. FOXP3+ Tregs require WASP to restrain Th2-mediated food allergy. J Clin Invest. 2016;126:4030-4044 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2b
Le Gars M, Haustant M, Klezovich Bénard M, Paget C, Trottein F, Goossens P, et al. Mechanisms of Invariant NKT Cell Activity in Restraining Bacillus anthracis Systemic Dissemination. J Immunol. 2016;197:3225-3232 pubmed
  • flow cytometry; mouse; loading ...; fig 5b
Papadaki G, Kambas K, Choulaki C, Vlachou K, Drakos E, Bertsias G, et al. Neutrophil extracellular traps exacerbate Th1-mediated autoimmune responses in rheumatoid arthritis by promoting DC maturation. Eur J Immunol. 2016;46:2542-2554 pubmed publisher
  • flow cytometry; mouse; loading ...
Ladle B, Li K, Phillips M, Pucsek A, Haile A, Powell J, et al. De novo DNA methylation by DNA methyltransferase 3a controls early effector CD8+ T-cell fate decisions following activation. Proc Natl Acad Sci U S A. 2016;113:10631-6 pubmed publisher
  • flow cytometry; mouse; fig 1a
Ulges A, Witsch E, Pramanik G, Klein M, Birkner K, Bühler U, et al. Protein kinase CK2 governs the molecular decision between encephalitogenic TH17 cell and Treg cell development. Proc Natl Acad Sci U S A. 2016;113:10145-50 pubmed publisher
  • flow cytometry; mouse; fig 1
Wang H, Li M, Hung C, Sinha M, Lee L, Wiesner D, et al. MyD88 Shapes Vaccine Immunity by Extrinsically Regulating Survival of CD4+ T Cells during the Contraction Phase. PLoS Pathog. 2016;12:e1005787 pubmed publisher
  • flow cytometry; mouse; 1:400; loading ...; tbl s2
Leong Y, Chen Y, Ong H, Wu D, Man K, Deléage C, et al. CXCR5(+) follicular cytotoxic T cells control viral infection in B cell follicles. Nat Immunol. 2016;17:1187-96 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b
Cheng H, Gaddis D, Wu R, McSkimming C, Haynes L, Taylor A, et al. Loss of ABCG1 influences regulatory T cell differentiation and atherosclerosis. J Clin Invest. 2016;126:3236-46 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4a
Ferreirinha P, Pérez Cabezas B, Correia A, Miyazawa B, França A, Carvalhais V, et al. Poly-N-Acetylglucosamine Production by Staphylococcus epidermidis Cells Increases Their In Vivo Proinflammatory Effect. Infect Immun. 2016;84:2933-43 pubmed publisher
  • flow cytometry; mouse; fig 5
Kritikou J, Dahlberg C, Baptista M, Wagner A, Banerjee P, Gwalani L, et al. IL-2 in the tumor microenvironment is necessary for Wiskott-Aldrich syndrome protein deficient NK cells to respond to tumors in vivo. Sci Rep. 2016;6:30636 pubmed publisher
  • flow cytometry; mouse; fig 3f
Biton J, Khaleghparast Athari S, Thiolat A, Santinon F, Lemeiter D, Hervé R, et al. In Vivo Expansion of Activated Foxp3+ Regulatory T Cells and Establishment of a Type 2 Immune Response upon IL-33 Treatment Protect against Experimental Arthritis. J Immunol. 2016;197:1708-19 pubmed publisher
  • flow cytometry; mouse; 1:50; loading ...; fig s5b
Göbel K, Pankratz S, Asaridou C, Herrmann A, Bittner S, Merker M, et al. Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells. Nat Commun. 2016;7:11626 pubmed publisher
  • flow cytometry; mouse; fig 7
Brandstätter O, Schanz O, Vorac J, König J, Mori T, Maruyama T, et al. Balancing intestinal and systemic inflammation through cell type-specific expression of the aryl hydrocarbon receptor repressor. Sci Rep. 2016;6:26091 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 1c
O Leary C, Riling C, Spruce L, Ding H, Kumar S, Deng G, et al. Ndfip-mediated degradation of Jak1 tunes cytokine signalling to limit expansion of CD4+ effector T cells. Nat Commun. 2016;7:11226 pubmed publisher
  • flow cytometry; mouse; fig 4
Sim C, Cho Y, Kim B, Baek I, Kim Y, Lee M. 2'-5' Oligoadenylate synthetase-like 1 (OASL1) deficiency in mice promotes an effective anti-tumor immune response by enhancing the production of type I interferons. Cancer Immunol Immunother. 2016;65:663-75 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
Smith R, Reyes N, Khandelwal P, Schlereth S, Lee H, Masli S, et al. Secondary allergic T cell responses are regulated by dendritic cell-derived thrombospondin-1 in the setting of allergic eye disease. J Leukoc Biol. 2016;100:371-80 pubmed publisher
  • ELISA; mouse; fig 2
Haque M, Song J, Fino K, Sandhu P, Song X, Lei F, et al. Stem cell-derived tissue-associated regulatory T cells ameliorate the development of autoimmunity. Sci Rep. 2016;6:20588 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5c
Foks A, Engelbertsen D, Kuperwaser F, Alberts Grill N, Gonen A, Witztum J, et al. Blockade of Tim-1 and Tim-4 Enhances Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice. Arterioscler Thromb Vasc Biol. 2016;36:456-65 pubmed publisher
  • flow cytometry; mouse; fig 3
Maelfait J, Roose K, Vereecke L, Mc Guire C, Sze M, Schuijs M, et al. A20 Deficiency in Lung Epithelial Cells Protects against Influenza A Virus Infection. PLoS Pathog. 2016;12:e1005410 pubmed publisher
  • flow cytometry; mouse; fig 2
Catarinella M, Monestiroli A, Escobar G, Fiocchi A, Tran N, Aiolfi R, et al. IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment. EMBO Mol Med. 2016;8:155-70 pubmed publisher
  • flow cytometry; mouse; fig 4
Vivar O, Masi G, Carpier J, Magalhaes J, Galgano D, Pazour G, et al. IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo. Proc Natl Acad Sci U S A. 2016;113:386-91 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1A; 2D
Everts B, Tussiwand R, Dreesen L, Fairfax K, Huang S, Smith A, et al. Migratory CD103+ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12. J Exp Med. 2016;213:35-51 pubmed publisher
  • flow cytometry; mouse; fig 5
Okada K, Sato S, Sato A, Mandelboim O, Yamasoba T, Kiyono H. Identification and Analysis of Natural Killer Cells in Murine Nasal Passages. PLoS ONE. 2015;10:e0142920 pubmed publisher
  • flow cytometry; mouse; fig 5
Fontinha D, Lopes F, Marques S, Alenquer M, Simas J. Murid Gammaherpesvirus Latency-Associated Protein M2 Promotes the Formation of Conjugates between Transformed B Lymphoma Cells and T Helper Cells. PLoS ONE. 2015;10:e0142540 pubmed publisher
  • flow cytometry; mouse; fig 3
Verma S, Weiskopf D, Gupta A, McDonald B, Peters B, Sette A, et al. Cytomegalovirus-Specific CD4 T Cells Are Cytolytic and Mediate Vaccine Protection. J Virol. 2016;90:650-8 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
Manlove L, Berquam Vrieze K, Pauken K, Williams R, Jenkins M, Farrar M. Adaptive Immunity to Leukemia Is Inhibited by Cross-Reactive Induced Regulatory T Cells. J Immunol. 2015;195:4028-37 pubmed publisher
  • ELISA; mouse; fig 5
Poncini C, Ilarregui J, Batalla E, Engels S, Cerliani J, Cucher M, et al. Trypanosoma cruzi Infection Imparts a Regulatory Program in Dendritic Cells and T Cells via Galectin-1-Dependent Mechanisms. J Immunol. 2015;195:3311-24 pubmed publisher
  • flow cytometry; mouse
Redpath S, Van Der Werf N, MacDonald A, Maizels R, Taylor M. Schistosoma mansoni Larvae Do Not Expand or Activate Foxp3+ Regulatory T Cells during Their Migratory Phase. Infect Immun. 2015;83:3881-9 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3a
Abt M, Lewis B, Caballero S, Xiong H, Carter R, Sušac B, et al. Innate Immune Defenses Mediated by Two ILC Subsets Are Critical for Protection against Acute Clostridium difficile Infection. Cell Host Microbe. 2015;18:27-37 pubmed publisher
  • flow cytometry; mouse
  • ELISA; mouse; 1 ug/ml
Puntambekar S, Hinton D, Yin X, Savarin C, Bergmann C, Trapp B, et al. Interleukin-10 is a critical regulator of white matter lesion containment following viral induced demyelination. Glia. 2015;63:2106-2120 pubmed publisher
  • flow cytometry; mouse
Ackerknecht M, Hauser M, Legler D, Stein J. In vivo TCR Signaling in CD4(+) T Cells Imprints a Cell-Intrinsic, Transient Low-Motility Pattern Independent of Chemokine Receptor Expression Levels, or Microtubular Network, Integrin, and Protein Kinase C Activity. Front Immunol. 2015;6:297 pubmed publisher
  • flow cytometry; mouse; fig 2c
Moguche A, Shafiani S, Clemons C, Larson R, Dinh C, Higdon L, et al. ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis. J Exp Med. 2015;212:715-28 pubmed publisher
  • flow cytometry; mouse
Dahlgren M, Gustafsson Hedberg T, Livingston M, Cucak H, Alsén S, Yrlid U, et al. T follicular helper, but not Th1, cell differentiation in the absence of conventional dendritic cells. J Immunol. 2015;194:5187-99 pubmed publisher
  • flow cytometry; mouse
Sakala I, Chaudhri G, Eldi P, Buller R, Karupiah G. Deficiency in Th2 cytokine responses exacerbate orthopoxvirus infection. PLoS ONE. 2015;10:e0118685 pubmed publisher
  • western blot; mouse; 1:100; fig 5,6
Hsiao H, Hsu T, Liu W, Hsieh W, Chou T, Wu Y, et al. Deltex1 antagonizes HIF-1α and sustains the stability of regulatory T cells in vivo. Nat Commun. 2015;6:6353 pubmed publisher
  • flow cytometry; mouse
Spada R, Rojas J, Pérez Yagüe S, Mulens V, Cannata Ortiz P, Bragado R, et al. NKG2D ligand overexpression in lupus nephritis correlates with increased NK cell activity and differentiation in kidneys but not in the periphery. J Leukoc Biol. 2015;97:583-98 pubmed publisher
  • flow cytometry; mouse
Rutz S, Kayagaki N, Phung Q, Eidenschenk C, Noubade R, Wang X, et al. Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells. Nature. 2015;518:417-21 pubmed publisher
  • flow cytometry; mouse
Mouchacca P, Chasson L, Frick M, Foray C, Schmitt Verhulst A, Boyer C. Visualization of granzyme B-expressing CD8 T cells during primary and secondary immune responses to Listeria monocytogenes. Immunology. 2015;145:24-33 pubmed publisher
  • flow cytometry; mouse; fig 2
Boding L, Hansen A, Meroni G, Johansen B, Braunstein T, Bonefeld C, et al. Midline 1 directs lytic granule exocytosis and cytotoxicity of mouse killer T cells. Eur J Immunol. 2014;44:3109-18 pubmed publisher
  • flow cytometry; mouse
Pick J, Arra A, Lingel H, Hegel J, Huber M, Nishanth G, et al. CTLA-4 (CD152) enhances the Tc17 differentiation program. Eur J Immunol. 2014;44:2139-52 pubmed publisher
  • flow cytometry; mouse
Cochain C, Chaudhari S, Koch M, Wiendl H, Eckstein H, Zernecke A. Programmed cell death-1 deficiency exacerbates T cell activation and atherogenesis despite expansion of regulatory T cells in atherosclerosis-prone mice. PLoS ONE. 2014;9:e93280 pubmed publisher
  • flow cytometry; mouse
Takei S, Omoto C, Kitagawa K, Morishita N, Katayama T, Shigemura K, et al. Oral administration of genetically modified Bifidobacterium displaying HCV-NS3 multi-epitope fusion protein could induce an HCV-NS3-specific systemic immune response in mice. Vaccine. 2014;32:3066-74 pubmed publisher
  • flow cytometry; mouse
Samuelson E, Laird R, Papillion A, Tatum A, Princiotta M, Hayes S. Reduced B lymphoid kinase (Blk) expression enhances proinflammatory cytokine production and induces nephrosis in C57BL/6-lpr/lpr mice. PLoS ONE. 2014;9:e92054 pubmed publisher
  • flow cytometry; mouse
Martins K, Steffens J, Van Tongeren S, Wells J, Bergeron A, Dickson S, et al. Toll-like receptor agonist augments virus-like particle-mediated protection from Ebola virus with transient immune activation. PLoS ONE. 2014;9:e89735 pubmed publisher
  • ELISA; mouse; 2 ug/ml
Medina Armenteros Y, Farinha Arcieri L, Braga C, Carromeu C, Tamura R, Ventura A. Mapping of CD8 T cell epitopes in human respiratory syncytial virus L protein. Intervirology. 2014;57:55-64 pubmed publisher
  • flow cytometry; mouse; fig 4
Jayaraman A, Jackson D, Message S, Pearson R, Aniscenko J, Caramori G, et al. IL-15 complexes induce NK- and T-cell responses independent of type I IFN signaling during rhinovirus infection. Mucosal Immunol. 2014;7:1151-64 pubmed publisher
  • flow cytometry; mouse
Kim E, Gasper D, Lee S, Plisch E, Svaren J, Suresh M. Bach2 regulates homeostasis of Foxp3+ regulatory T cells and protects against fatal lung disease in mice. J Immunol. 2014;192:985-95 pubmed publisher
  • blocking or activating experiments; mouse; 5 ug/ml
Iwata A, Kawashima S, Kobayashi M, Okubo A, Kawashima H, Suto A, et al. Th2-type inflammation instructs inflammatory dendritic cells to induce airway hyperreactivity. Int Immunol. 2014;26:103-14 pubmed publisher
  • flow cytometry; mouse
Murapa P, Ward M, Gandhapudi S, Woodward J, D Orazio S. Heat shock factor 1 protects mice from rapid death during Listeria monocytogenes infection by regulating expression of tumor necrosis factor alpha during fever. Infect Immun. 2011;79:177-84 pubmed publisher
  • flow cytometry; mouse; fig 6C
Nakae S, Iwakura Y, Suto H, Galli S. Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17. J Leukoc Biol. 2007;81:1258-68 pubmed
Akgul A, Maddaloni M, Jun S, Nelson A, Odreman V, Hoffman C, et al. Stimulation of regulatory T cells with Lactococcus lactis expressing enterotoxigenic E. coli colonization factor antigen 1 retains salivary flow in a genetic model of Sjögren's syndrome. Arthritis Res Ther. 2021;23:99 pubmed publisher
Harbour S, DiToro D, Witte S, Zindl C, Gao M, Schoeb T, et al. TH17 cells require ongoing classic IL-6 receptor signaling to retain transcriptional and functional identity. Sci Immunol. 2020;5: pubmed publisher
Shu L, Zhong L, Xiao Y, Wu X, Liu Y, Jiang X, et al. Neutrophil elastase triggers the development of autoimmune diabetes by exacerbating innate immune responses in pancreatic islets of non-obese diabetic mice. Clin Sci (Lond). 2020;134:1679-1696 pubmed publisher
Ghergurovich J, García Cañaveras J, Wang J, Schmidt E, Zhang Z, Teslaa T, et al. A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway. Nat Chem Biol. 2020;16:731-739 pubmed publisher
Álvarez Salamero C, Castillo González R, Pastor Fernández G, Mariblanca I, Pino J, Cibrian D, et al. IL-23 signaling regulation of pro-inflammatory T-cell migration uncovered by phosphoproteomics. PLoS Biol. 2020;18:e3000646 pubmed publisher
Okumura G, Iguchi Manaka A, Murata R, Yamashita Kanemaru Y, Shibuya A, Shibuya K. Tumor-derived soluble CD155 inhibits DNAM-1-mediated antitumor activity of natural killer cells. J Exp Med. 2020;217: pubmed publisher
Yan J, Allen S, McDonald E, Das I, Mak J, Liu L, et al. MAIT Cells Promote Tumor Initiation, Growth, and Metastases via Tumor MR1. Cancer Discov. 2019;: pubmed publisher
Wang L, Shen E, Luo L, Rabe H, Wang Q, Yin J, et al. Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor. Cell Rep. 2019;29:1848-1861.e6 pubmed publisher
Petermann F, Pekowska A, Johnson C, Jankovic D, Shih H, Jiang K, et al. The Magnitude of IFN-γ Responses Is Fine-Tuned by DNA Architecture and the Non-coding Transcript of Ifng-as1. Mol Cell. 2019;75:1229-1242.e5 pubmed publisher
Ponzetta A, Carriero R, Carnevale S, Barbagallo M, Molgora M, Perucchini C, et al. Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors. Cell. 2019;178:346-360.e24 pubmed publisher
Sorini C, Cosorich I, Lo Conte M, De Giorgi L, Facciotti F, Lucianò R, et al. Loss of gut barrier integrity triggers activation of islet-reactive T cells and autoimmune diabetes. Proc Natl Acad Sci U S A. 2019;: pubmed publisher
Maynard S, Marshall J, MacGill R, Yu L, Cann J, Cheng L, et al. Vaccination with synthetic long peptide formulated with CpG in an oil-in-water emulsion induces robust E7-specific CD8 T cell responses and TC-1 tumor eradication. BMC Cancer. 2019;19:540 pubmed publisher
Wang W, Green M, Choi J, Gijon M, Kennedy P, Johnson J, et al. CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy. Nature. 2019;569:270-274 pubmed publisher
Yamamoto T, Lee P, Vodnala S, Gurusamy D, Kishton R, Yu Z, et al. T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy. J Clin Invest. 2019;129:1551-1565 pubmed publisher
Salem M, Wallace C, Velegraki M, Li A, Ansa Addo E, Metelli A, et al. GARP Dampens Cancer Immunity by Sustaining Function and Accumulation of Regulatory T Cells in the Colon. Cancer Res. 2019;: pubmed publisher
Chea L, Wyatt L, Gangadhara S, Moss B, Amara R. Novel Modified Vaccinia Virus Ankara Vector Expressing Anti-apoptotic Gene B13R Delays Apoptosis and Enhances Humoral Responses. J Virol. 2019;93: pubmed publisher
Walsh S, Bastin D, Chen L, Nguyen A, Storbeck C, Lefebvre C, et al. Type I IFN blockade uncouples immunotherapy-induced antitumor immunity and autoimmune toxicity. J Clin Invest. 2019;129:518-530 pubmed publisher
Mulati K, Hamanishi J, Matsumura N, Chamoto K, Mise N, Abiko K, et al. VISTA expressed in tumour cells regulates T cell function. Br J Cancer. 2019;120:115-127 pubmed publisher
Grohmann M, Wiede F, Dodd G, Gurzov E, Ooi G, Butt T, et al. Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC. Cell. 2018;175:1289-1306.e20 pubmed publisher
Bhutiani N, Li Q, Anderson C, Gallagher H, De Jesus M, Singh R, et al. Enhanced gut barrier integrity sensitizes colon cancer to immune therapy. Oncoimmunology. 2018;7:e1498438 pubmed publisher
Lee S, Park H, Cheon J, Wu L, Van Kaer L, Hong S. iNKT Cells Suppress Pathogenic NK1.1+CD8+ T Cells in DSS-Induced Colitis. Front Immunol. 2018;9:2168 pubmed publisher
Qiu J, Peng S, Ma Y, Yang A, Farmer E, Cheng M, et al. Epithelial boost enhances antigen expression by vaccinia virus for the generation of potent CD8+ T cell-mediated antitumor immunity following DNA priming vaccination. Virology. 2018;525:205-215 pubmed publisher
Almeida F, Tognarelli S, Marcais A, Kueh A, Friede M, Liao Y, et al. A point mutation in the Ncr1 signal peptide impairs the development of innate lymphoid cell subsets. Oncoimmunology. 2018;7:e1475875 pubmed publisher
Badamchi Zadeh A, Moynihan K, Larocca R, Aid M, Provine N, Iampietro M, et al. Combined HDAC and BET Inhibition Enhances Melanoma Vaccine Immunogenicity and Efficacy. J Immunol. 2018;201:2744-2752 pubmed publisher
Lasso P, Gomez Cadena A, Urueña C, Donda A, Martinez Usatorre A, Barreto A, et al. Prophylactic vs. Therapeutic Treatment With P2Et Polyphenol-Rich Extract Has Opposite Effects on Tumor Growth. Front Oncol. 2018;8:356 pubmed publisher
Giles D, Duncker P, Wilkinson N, Washnock Schmid J, Segal B. CNS-resident classical DCs play a critical role in CNS autoimmune disease. J Clin Invest. 2018;128:5322-5334 pubmed publisher
Tanaka S, Suto A, Iwamoto T, Kageyama T, Tamachi T, Takatori H, et al. Sox12 promotes T reg differentiation in the periphery during colitis. J Exp Med. 2018;215:2509-2519 pubmed publisher
Napier R, Lee E, Vance E, Snow P, Samson K, Dawson C, et al. Nod2 Deficiency Augments Th17 Responses and Exacerbates Autoimmune Arthritis. J Immunol. 2018;201:1889-1898 pubmed publisher
Cheng Y, Zhu X, Wang X, Zhuang Q, Huyan X, Sun X, et al. Trichinella spiralis Infection Mitigates Collagen-Induced Arthritis via Programmed Death 1-Mediated Immunomodulation. Front Immunol. 2018;9:1566 pubmed publisher
Deason K, Troutman T, Jain A, Challa D, Mandraju R, Brewer T, et al. BCAP links IL-1R to the PI3K-mTOR pathway and regulates pathogenic Th17 cell differentiation. J Exp Med. 2018;215:2413-2428 pubmed publisher
Kim Y, Kim K, Ko E, Kim M, Lee Y, Jung Y, et al. Complement C3 Plays a Key Role in Inducing Humoral and Cellular Immune Responses to Influenza Virus Strain-Specific Hemagglutinin-Based or Cross-Protective M2 Extracellular Domain-Based Vaccination. J Virol. 2018;92: pubmed publisher
Maurice D, Costello P, Sargent M, Treisman R. ERK Signaling Controls Innate-like CD8+ T Cell Differentiation via the ELK4 (SAP-1) and ELK1 Transcription Factors. J Immunol. 2018;201:1681-1691 pubmed publisher
Diao J, Gu H, Tang M, Zhao J, Cattral M. Tumor Dendritic Cells (DCs) Derived from Precursors of Conventional DCs Are Dispensable for Intratumor CTL Responses. J Immunol. 2018;201:1306-1314 pubmed publisher
Smithey M, Venturi V, Davenport M, Buntzman A, Vincent B, Frelinger J, et al. Lifelong CMV infection improves immune defense in old mice by broadening the mobilized TCR repertoire against third-party infection. Proc Natl Acad Sci U S A. 2018;115:E6817-E6825 pubmed publisher
Barik S, Miller M, Cattin Roy A, Ukah T, Zaghouani H. A distinct dendritic cell population arises in the thymus of IL-13Rα1-sufficient but not IL-13Rα1-deficient mice. Cell Immunol. 2018;331:130-136 pubmed publisher
Manresa Arraut A, Johansen F, Brakebusch C, Issazadeh Navikas S, Hasseldam H. RhoA Drives T-Cell Activation and Encephalitogenic Potential in an Animal Model of Multiple Sclerosis. Front Immunol. 2018;9:1235 pubmed publisher
Lu J, Duan X, Zhao W, Wang J, Wang H, Zhou K, et al. Aged Mice are More Resistant to Influenza Virus Infection due to Reduced Inflammation and Lung Pathology. Aging Dis. 2018;9:358-373 pubmed publisher
Wei B, Zhang R, Zhai J, Zhu J, Yang F, Yue D, et al. Suppression of Th17 Cell Response in the Alleviation of Dextran Sulfate Sodium-Induced Colitis by Ganoderma lucidum Polysaccharides. J Immunol Res. 2018;2018:2906494 pubmed publisher
Kishta O, Sabourin A, Simon L, McGovern T, Raymond M, Galbas T, et al. March1 E3 Ubiquitin Ligase Modulates Features of Allergic Asthma in an Ovalbumin-Induced Mouse Model of Lung Inflammation. J Immunol Res. 2018;2018:3823910 pubmed publisher
Sen S, He Z, Ghosh S, DERY K, Yang L, Zhang J, et al. PRMT1 Plays a Critical Role in Th17 Differentiation by Regulating Reciprocal Recruitment of STAT3 and STAT5. J Immunol. 2018;201:440-450 pubmed publisher
Zhu J, Liu J, Liu Z, Wu L, Shi M, Zhang J, et al. Interleukin-27 Gene Therapy Prevents the Development of Autoimmune Encephalomyelitis but Fails to Attenuate Established Inflammation due to the Expansion of CD11b+Gr-1+ Myeloid Cells. Front Immunol. 2018;9:873 pubmed publisher
Ngo Thai Bich V, Hongu T, Miura Y, Katagiri N, Ohbayashi N, Yamashita Kanemaru Y, et al. Physiological function of phospholipase D2 in anti-tumor immunity: regulation of CD8+ T lymphocyte proliferation. Sci Rep. 2018;8:6283 pubmed publisher
Zheng X, Fang Z, Liu X, Deng S, Zhou P, Wang X, et al. Increased vessel perfusion predicts the efficacy of immune checkpoint blockade. J Clin Invest. 2018;128:2104-2115 pubmed publisher
Treise I, Huber E, Klein Rodewald T, Heinemeyer W, Grassmann S, Basler M, et al. Defective immuno- and thymoproteasome assembly causes severe immunodeficiency. Sci Rep. 2018;8:5975 pubmed publisher
Khong H, Volmari A, Sharma M, Dai Z, Imo C, Hailemichael Y, et al. Peptide Vaccine Formulation Controls the Duration of Antigen Presentation and Magnitude of Tumor-Specific CD8+ T Cell Response. J Immunol. 2018;200:3464-3474 pubmed publisher
Iampietro M, Larocca R, Provine N, Abbink P, Kang Z, Bricault C, et al. Immunogenicity and Cross-Reactivity of Rhesus Adenoviral Vectors. J Virol. 2018;92: pubmed publisher
Gaddis D, Padgett L, Wu R, McSkimming C, Romines V, Taylor A, et al. Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis. Nat Commun. 2018;9:1095 pubmed publisher
Vaartjes D, Nandakumar K, Holmdahl R, Raposo B. Increased salt exposure affects both lymphoid and myeloid effector functions, influencing innate-associated disease but not T-cell-associated autoimmunity. Immunology. 2018;: pubmed publisher
Hwang M, Bergmann C. Alpha/Beta Interferon (IFN-?/?) Signaling in Astrocytes Mediates Protection against Viral Encephalomyelitis and Regulates IFN-?-Dependent Responses. J Virol. 2018;92: pubmed publisher
Hailemichael Y, Woods A, Fu T, He Q, Nielsen M, Hasan F, et al. Cancer vaccine formulation dictates synergy with CTLA-4 and PD-L1 checkpoint blockade therapy. J Clin Invest. 2018;128:1338-1354 pubmed publisher
Yates K, Bi K, Haining W, Cantor H, Kim H. Comparative transcriptome analysis reveals distinct genetic modules associated with Helios expression in intratumoral regulatory T cells. Proc Natl Acad Sci U S A. 2018;115:2162-2167 pubmed publisher
Zhao M, Tan Y, Peng Q, Huang C, Guo Y, Liang G, et al. IL-6/STAT3 pathway induced deficiency of RFX1 contributes to Th17-dependent autoimmune diseases via epigenetic regulation. Nat Commun. 2018;9:583 pubmed publisher
Dillen C, Pinsker B, Marusina A, Merleev A, Farber O, Liu H, et al. Clonally expanded γδ T cells protect against Staphylococcus aureus skin reinfection. J Clin Invest. 2018;128:1026-1042 pubmed publisher
Cortes J, Ambesi Impiombato A, Couronné L, Quinn S, Kim C, da Silva Almeida A, et al. RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis. Cancer Cell. 2018;33:259-273.e7 pubmed publisher
Hsieh W, Hsu T, Chang Y, Lai M. IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells. Nat Commun. 2018;9:463 pubmed publisher
Kip E, Staal J, Verstrepen L, Tima H, Terryn S, Romano M, et al. MALT1 Controls Attenuated Rabies Virus by Inducing Early Inflammation and T Cell Activation in the Brain. J Virol. 2018;92: pubmed publisher
Linehan J, Harrison O, Han S, Byrd A, Vujkovic Cvijin I, Villarino A, et al. Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair. Cell. 2018;172:784-796.e18 pubmed publisher
Reynolds C, Suleyman O, Ortega Prieto A, Skelton J, Bonnesoeur P, Blohm A, et al. T cell immunity to Zika virus targets immunodominant epitopes that show cross-reactivity with other Flaviviruses. Sci Rep. 2018;8:672 pubmed publisher
Choi I, Wang Z, Ke Q, Hong M, Qian Y, Zhao X, et al. Signaling by the Epstein-Barr virus LMP1 protein induces potent cytotoxic CD4+ and CD8+ T cell responses. Proc Natl Acad Sci U S A. 2018;115:E686-E695 pubmed publisher
Duncker P, Stoolman J, Huber A, Segal B. GM-CSF Promotes Chronic Disability in Experimental Autoimmune Encephalomyelitis by Altering the Composition of Central Nervous System-Infiltrating Cells, but Is Dispensable for Disease Induction. J Immunol. 2018;200:966-973 pubmed publisher
Stutz M, Ojaimi S, Allison C, Preston S, Arandjelovic P, Hildebrand J, et al. Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted. Cell Death Differ. 2018;25:951-965 pubmed publisher
Xu L, Ding W, Stohl L, Zhou X, Azizi S, Chuang E, et al. Regulation of T Helper Cell Responses During Antigen Presentation by Norepinephrine-exposed Endothelial Cells. Immunology. 2017;: pubmed publisher
Wasiuk A, Testa J, Weidlick J, Sisson C, Vitale L, Widger J, et al. CD27-Mediated Regulatory T Cell Depletion and Effector T Cell Costimulation Both Contribute to Antitumor Efficacy. J Immunol. 2017;199:4110-4123 pubmed publisher
Patel S, Yokoyama W. CD8+ T Cells Prevent Lethality from Neonatal Murine Roseolovirus Infection. J Immunol. 2017;199:3212-3221 pubmed publisher
De Feo D, Merlini A, Brambilla E, Ottoboni L, Laterza C, Menon R, et al. Neural precursor cell-secreted TGF-β2 redirects inflammatory monocyte-derived cells in CNS autoimmunity. J Clin Invest. 2017;127:3937-3953 pubmed publisher
Sierra R, Trillo Tinoco J, Mohamed E, Yu L, Achyut B, Arbab A, et al. Anti-Jagged Immunotherapy Inhibits MDSCs and Overcomes Tumor-Induced Tolerance. Cancer Res. 2017;77:5628-5638 pubmed publisher
Chen Z, Stelekati E, Kurachi M, Yu S, Cai Z, Manne S, et al. miR-150 Regulates Memory CD8 T Cell Differentiation via c-Myb. Cell Rep. 2017;20:2584-2597 pubmed publisher
Moroda M, Takamoto M, Iwakura Y, Nakayama J, Aosai F. Interleukin-17A-Deficient Mice Are Highly Susceptible to Toxoplasma gondii Infection Due to Excessively Induced T. gondii HSP70 and Interferon Gamma Production. Infect Immun. 2017;85: pubmed publisher
Madireddi S, Eun S, Mehta A, Birta A, Zajonc D, Niki T, et al. Regulatory T Cell-Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9. J Immunol. 2017;199:2721-2728 pubmed publisher
Muschaweckh A, Petermann F, Korn T. IL-1? and IL-23 Promote Extrathymic Commitment of CD27+CD122- ?? T Cells to ??T17 Cells. J Immunol. 2017;199:2668-2679 pubmed publisher
Poston T, Qu Y, Girardi J, O Connell C, Frazer L, Russell A, et al. A Chlamydia-Specific TCR-Transgenic Mouse Demonstrates Th1 Polyfunctionality with Enhanced Effector Function. J Immunol. 2017;199:2845-2854 pubmed publisher
Kim D, Dastidar H, Zhang C, Zemp F, Lau K, Ernst M, et al. Smac mimetics and oncolytic viruses synergize in driving anticancer T-cell responses through complementary mechanisms. Nat Commun. 2017;8:344 pubmed publisher
Kunnath Velayudhan S, Goldberg M, Saini N, Johndrow C, Ng T, Johnson A, et al. Transcriptome Analysis of Mycobacteria-Specific CD4+ T Cells Identified by Activation-Induced Expression of CD154. J Immunol. 2017;199:2596-2606 pubmed publisher
Bucsek M, Qiao G, MacDonald C, Giridharan T, Evans L, Niedzwecki B, et al. β-Adrenergic Signaling in Mice Housed at Standard Temperatures Suppresses an Effector Phenotype in CD8+ T Cells and Undermines Checkpoint Inhibitor Therapy. Cancer Res. 2017;77:5639-5651 pubmed publisher
Machelart A, Khadrawi A, Demars A, Willemart K, De Trez C, Letesson J, et al. Chronic Brucella Infection Induces Selective and Persistent Interferon Gamma-Dependent Alterations of Marginal Zone Macrophages in the Spleen. Infect Immun. 2017;85: pubmed publisher
Barik S, Ellis J, Cascio J, Miller M, Ukah T, Cattin Roy A, et al. IL-4/IL-13 Heteroreceptor Influences Th17 Cell Conversion and Sensitivity to Regulatory T Cell Suppression To Restrain Experimental Allergic Encephalomyelitis. J Immunol. 2017;199:2236-2248 pubmed publisher
Li D, Ren Z. Cordyceps sinensis promotes immune regulation and enhances bacteriostatic activity of PA-824 via IL-10 in Mycobacterium tuberculosis disease. Braz J Med Biol Res. 2017;50:e6188 pubmed publisher
Ghosh M, Muller H, Walker A. Lactation-Based Maternal Educational Immunity Crosses MHC Class I Barriers and Can Impart Th1 Immunity to Th2-Biased Recipients. J Immunol. 2017;199:1729-1736 pubmed publisher
Nagalingam G, Vinuesa C, Britton W, Saunders B. Modulation of Roquin Function in Myeloid Cells Reduces Mycobacterium tuberculosis-Induced Inflammation. J Immunol. 2017;199:1796-1804 pubmed publisher
Wu X, Dayanand K, Thylur R, Norbury C, Gowda D. Small molecule-based inhibition of MEK1/2 proteins dampens inflammatory responses to malaria, reduces parasite load, and mitigates pathogenic outcomes. J Biol Chem. 2017;292:13615-13634 pubmed publisher
Miosge L, Sontani Y, Chuah A, Horikawa K, Russell T, Mei Y, et al. Systems-guided forward genetic screen reveals a critical role of the replication stress response protein ETAA1 in T cell clonal expansion. Proc Natl Acad Sci U S A. 2017;114:E5216-E5225 pubmed publisher
Ripamonti C, Bishop L, Kovacs J. Pulmonary Interleukin-17-Positive Lymphocytes Increase during Pneumocystis murina Infection but Are Not Required for Clearance of Pneumocystis. Infect Immun. 2017;85: pubmed publisher
Fenske R, Cadena M, Harenda Q, Wienkes H, Carbajal K, Schaid M, et al. The Inhibitory G Protein ?-Subunit, G?z, Promotes Type 1 Diabetes-Like Pathophysiology in NOD Mice. Endocrinology. 2017;158:1645-1658 pubmed publisher
Thylur R, Wu X, Gowda N, Punnath K, Neelgund S, Febbraio M, et al. CD36 receptor regulates malaria-induced immune responses primarily at early blood stage infection contributing to parasitemia control and resistance to mortality. J Biol Chem. 2017;292:9394-9408 pubmed publisher
Bardina S, Brown J, Michlmayr D, Hoffman K, Sum J, Pletnev A, et al. Chemokine Receptor Ccr7 Restricts Fatal West Nile Virus Encephalitis. J Virol. 2017;91: pubmed publisher
Xiang B, Baybutt T, Berman Booty L, Magee M, Waldman S, Alexeev V, et al. Prime-Boost Immunization Eliminates Metastatic Colorectal Cancer by Producing High-Avidity Effector CD8+ T Cells. J Immunol. 2017;198:3507-3514 pubmed publisher
Brandstadter J, Chen H, Jiang S, Huang X, Yang Y. IL-18-dependent NKG2D ligand upregulation on accessory cells is mediated by the PI3K/GSK-3 pathway. J Leukoc Biol. 2017;101:1317-1323 pubmed publisher
Franchi L, Monteleone I, Hao L, Spahr M, Zhao W, Liu X, et al. Inhibiting Oxidative Phosphorylation In Vivo Restrains Th17 Effector Responses and Ameliorates Murine Colitis. J Immunol. 2017;198:2735-2746 pubmed publisher
Markiewski M, Vadrevu S, Sharma S, Chintala N, Ghouse S, Cho J, et al. The Ribosomal Protein S19 Suppresses Antitumor Immune Responses via the Complement C5a Receptor 1. J Immunol. 2017;198:2989-2999 pubmed publisher
Wallberg M, Recino A, Phillips J, Howie D, Vienne M, Paluch C, et al. Anti-CD3 treatment up-regulates programmed cell death protein-1 expression on activated effector T cells and severely impairs their inflammatory capacity. Immunology. 2017;151:248-260 pubmed publisher
Hall O, Nachbagauer R, Vermillion M, Fink A, Phuong V, Krammer F, et al. Progesterone-Based Contraceptives Reduce Adaptive Immune Responses and Protection against Sequential Influenza A Virus Infections. J Virol. 2017;91: pubmed publisher
Tan J, Tedrow J, Nouraie M, Dutta J, Miller D, Li X, et al. Loss of Twist1 in the Mesenchymal Compartment Promotes Increased Fibrosis in Experimental Lung Injury by Enhanced Expression of CXCL12. J Immunol. 2017;198:2269-2285 pubmed publisher
Förster M, Boora R, Petrov J, Fodil N, Albanese I, Kim J, et al. A role for the histone H2A deubiquitinase MYSM1 in maintenance of CD8+ T cells. Immunology. 2017;151:110-121 pubmed publisher
Ehrlich A, Fernández O, Rodriguez Pinto D, Castilho T, Corral Caridad M, Goldsmith Pestana K, et al. Local Delivery of the Toll-Like Receptor 9 Ligand CpG Downregulates Host Immune and Inflammatory Responses, Ameliorating Established Leishmania (Viannia) panamensis Chronic Infection. Infect Immun. 2017;85: pubmed publisher
Opata M, Stephens R. Chronic Plasmodium chabaudi Infection Generates CD4 Memory T Cells with Increased T Cell Receptor Sensitivity but Poor Secondary Expansion and Increased Apoptosis. Infect Immun. 2017;85: pubmed publisher
Li M, Li Z, Yao Y, Jin W, Wood K, Liu Q, et al. Astrocyte-derived interleukin-15 exacerbates ischemic brain injury via propagation of cellular immunity. Proc Natl Acad Sci U S A. 2017;114:E396-E405 pubmed publisher
Li Y, Lu Y, Wang S, Han Z, Zhu F, Ni Y, et al. USP21 prevents the generation of T-helper-1-like Treg cells. Nat Commun. 2016;7:13559 pubmed publisher
Colluru V, McNeel D. B lymphocytes as direct antigen-presenting cells for anti-tumor DNA vaccines. Oncotarget. 2016;7:67901-67918 pubmed publisher
Brennan T, Lin L, Brandstadter J, Rendell V, Dredge K, Huang X, et al. Heparan sulfate mimetic PG545-mediated antilymphoma effects require TLR9-dependent NK cell activation. J Clin Invest. 2016;126:207-19 pubmed publisher
Xu X, Araki K, Li S, Han J, Ye L, Tan W, et al. Autophagy is essential for effector CD8(+) T cell survival and memory formation. Nat Immunol. 2014;15:1152-61 pubmed publisher
Shen P, Roch T, Lampropoulou V, O Connor R, Stervbo U, Hilgenberg E, et al. IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases. Nature. 2014;507:366-370 pubmed publisher
Fife B, Pauken K, Eagar T, Obu T, Wu J, Tang Q, et al. Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal. Nat Immunol. 2009;10:1185-92 pubmed publisher
Evans A, Moser J, Krug L, Pozharskaya V, Mora A, Speck S. A gammaherpesvirus-secreted activator of Vbeta4+ CD8+ T cells regulates chronic infection and immunopathology. J Exp Med. 2008;205:669-84 pubmed publisher
Jacobsen E, Ochkur S, Pero R, Taranova A, Protheroe C, Colbert D, et al. Allergic pulmonary inflammation in mice is dependent on eosinophil-induced recruitment of effector T cells. J Exp Med. 2008;205:699-710 pubmed publisher
Jain R, Tartar D, Gregg R, Divekar R, Bell J, Lee H, et al. Innocuous IFNgamma induced by adjuvant-free antigen restores normoglycemia in NOD mice through inhibition of IL-17 production. J Exp Med. 2008;205:207-18 pubmed publisher
Löhning M, Hegazy A, Pinschewer D, Busse D, Lang K, Hofer T, et al. Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors. J Exp Med. 2008;205:53-61 pubmed publisher
Hirota K, Yoshitomi H, Hashimoto M, Maeda S, Teradaira S, Sugimoto N, et al. Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. J Exp Med. 2007;204:2803-12 pubmed
Yachi P, Lotz C, Ampudia J, Gascoigne N. T cell activation enhancement by endogenous pMHC acts for both weak and strong agonists but varies with differentiation state. J Exp Med. 2007;204:2747-57 pubmed
Shimizu K, Kurosawa Y, Taniguchi M, Steinman R, Fujii S. Cross-presentation of glycolipid from tumor cells loaded with alpha-galactosylceramide leads to potent and long-lived T cell mediated immunity via dendritic cells. J Exp Med. 2007;204:2641-53 pubmed
Miyagi T, Gil M, Wang X, Louten J, Chu W, Biron C. High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells. J Exp Med. 2007;204:2383-96 pubmed
Kastenmuller W, Gasteiger G, Gronau J, Baier R, Ljapoci R, Busch D, et al. Cross-competition of CD8+ T cells shapes the immunodominance hierarchy during boost vaccination. J Exp Med. 2007;204:2187-98 pubmed
Scott Browne J, Shafiani S, Tucker Heard G, Ishida Tsubota K, Fontenot J, Rudensky A, et al. Expansion and function of Foxp3-expressing T regulatory cells during tuberculosis. J Exp Med. 2007;204:2159-69 pubmed
Narni Mancinelli E, Campisi L, Bassand D, Cazareth J, Gounon P, Glaichenhaus N, et al. Memory CD8+ T cells mediate antibacterial immunity via CCL3 activation of TNF/ROI+ phagocytes. J Exp Med. 2007;204:2075-87 pubmed
Ehirchiou D, Xiong Y, Xu G, Chen W, Shi Y, Zhang L. CD11b facilitates the development of peripheral tolerance by suppressing Th17 differentiation. J Exp Med. 2007;204:1519-24 pubmed
Delano M, Scumpia P, Weinstein J, Coco D, Nagaraj S, Kelly Scumpia K, et al. MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis. J Exp Med. 2007;204:1463-74 pubmed
Soares H, Waechter H, Glaichenhaus N, Mougneau E, Yagita H, Mizenina O, et al. A subset of dendritic cells induces CD4+ T cells to produce IFN-gamma by an IL-12-independent but CD70-dependent mechanism in vivo. J Exp Med. 2007;204:1095-106 pubmed
Loeser S, Loser K, Bijker M, Rangachari M, van der Burg S, Wada T, et al. Spontaneous tumor rejection by cbl-b-deficient CD8+ T cells. J Exp Med. 2007;204:879-91 pubmed
Schleicher U, Liese J, Knippertz I, Kurzmann C, Hesse A, Heit A, et al. NK cell activation in visceral leishmaniasis requires TLR9, myeloid DCs, and IL-12, but is independent of plasmacytoid DCs. J Exp Med. 2007;204:893-906 pubmed
Anderson C, Oukka M, Kuchroo V, Sacks D. CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis. J Exp Med. 2007;204:285-97 pubmed
Hirota K, Hashimoto M, Yoshitomi H, Tanaka S, Nomura T, Yamaguchi T, et al. T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis. J Exp Med. 2007;204:41-7 pubmed
Fife B, Guleria I, Gubbels Bupp M, Eagar T, Tang Q, Bour Jordan H, et al. Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway. J Exp Med. 2006;203:2737-47 pubmed
Kullberg M, Jankovic D, Feng C, Hue S, Gorelick P, McKenzie B, et al. IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis. J Exp Med. 2006;203:2485-94 pubmed
Yurchenko E, Tritt M, Hay V, Shevach E, Belkaid Y, Piccirillo C. CCR5-dependent homing of naturally occurring CD4+ regulatory T cells to sites of Leishmania major infection favors pathogen persistence. J Exp Med. 2006;203:2451-60 pubmed
Liang S, Tan X, Luxenberg D, Karim R, Dunussi Joannopoulos K, Collins M, et al. Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J Exp Med. 2006;203:2271-9 pubmed
Yu G, Xu X, Vu M, Kilpatrick E, Li X. NK cells promote transplant tolerance by killing donor antigen-presenting cells. J Exp Med. 2006;203:1851-8 pubmed
Fallon P, Ballantyne S, Mangan N, Barlow J, Dasvarma A, Hewett D, et al. Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion. J Exp Med. 2006;203:1105-16 pubmed
Trumpfheller C, Finke J, LOPEZ C, Moran T, Moltedo B, Soares H, et al. Intensified and protective CD4+ T cell immunity in mice with anti-dendritic cell HIV gag fusion antibody vaccine. J Exp Med. 2006;203:607-17 pubmed
Boscardin S, Hafalla J, Masilamani R, Kamphorst A, Zebroski H, Rai U, et al. Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses. J Exp Med. 2006;203:599-606 pubmed
Bajenoff M, Breart B, Huang A, Qi H, Cazareth J, Braud V, et al. Natural killer cell behavior in lymph nodes revealed by static and real-time imaging. J Exp Med. 2006;203:619-31 pubmed
Wilson M, Taylor M, Balic A, Finney C, Lamb J, Maizels R. Suppression of allergic airway inflammation by helminth-induced regulatory T cells. J Exp Med. 2005;202:1199-212 pubmed
Johansson Lindbom B, Svensson M, Pabst O, Palmqvist C, Marquez G, Forster R, et al. Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing. J Exp Med. 2005;202:1063-73 pubmed
Annacker O, Coombes J, Malmstrom V, Uhlig H, Bourne T, Johansson Lindbom B, et al. Essential role for CD103 in the T cell-mediated regulation of experimental colitis. J Exp Med. 2005;202:1051-61 pubmed
Yasunami Y, Kojo S, Kitamura H, Toyofuku A, Satoh M, Nakano M, et al. Valpha14 NK T cell-triggered IFN-gamma production by Gr-1+CD11b+ cells mediates early graft loss of syngeneic transplanted islets. J Exp Med. 2005;202:913-8 pubmed
Kihara Y, Ishii S, Kita Y, Toda A, Shimada A, Shimizu T. Dual phase regulation of experimental allergic encephalomyelitis by platelet-activating factor. J Exp Med. 2005;202:853-63 pubmed
Samy E, Parker L, Sharp C, Tung K. Continuous control of autoimmune disease by antigen-dependent polyclonal CD4+CD25+ regulatory T cells in the regional lymph node. J Exp Med. 2005;202:771-81 pubmed
Jelley Gibbs D, Brown D, Dibble J, Haynes L, Eaton S, Swain S. Unexpected prolonged presentation of influenza antigens promotes CD4 T cell memory generation. J Exp Med. 2005;202:697-706 pubmed
Yoneyama H, Matsuno K, Toda E, Nishiwaki T, Matsuo N, Nakano A, et al. Plasmacytoid DCs help lymph node DCs to induce anti-HSV CTLs. J Exp Med. 2005;202:425-35 pubmed
Obst R, van Santen H, Mathis D, Benoist C. Antigen persistence is required throughout the expansion phase of a CD4(+) T cell response. J Exp Med. 2005;201:1555-65 pubmed
Fahlén L, Read S, Gorelik L, Hurst S, Coffman R, Flavell R, et al. T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells. J Exp Med. 2005;201:737-46 pubmed
Grenningloh R, Kang B, Ho I. Ets-1, a functional cofactor of T-bet, is essential for Th1 inflammatory responses. J Exp Med. 2005;201:615-26 pubmed
Kim S, Cornberg M, Wang X, Chen H, Selin L, Welsh R. Private specificities of CD8 T cell responses control patterns of heterologous immunity. J Exp Med. 2005;201:523-33 pubmed
Mora J, Cheng G, Picarella D, Briskin M, Buchanan N, von Andrian U. Reciprocal and dynamic control of CD8 T cell homing by dendritic cells from skin- and gut-associated lymphoid tissues. J Exp Med. 2005;201:303-16 pubmed
Tscharke D, Karupiah G, Zhou J, Palmore T, Irvine K, Haeryfar S, et al. Identification of poxvirus CD8+ T cell determinants to enable rational design and characterization of smallpox vaccines. J Exp Med. 2005;201:95-104 pubmed
Amprey J, Im J, Turco S, Murray H, Illarionov P, Besra G, et al. A subset of liver NK T cells is activated during Leishmania donovani infection by CD1d-bound lipophosphoglycan. J Exp Med. 2004;200:895-904 pubmed
Bai X, Li O, Zhou Q, Zhang H, Joshi P, Zheng X, et al. CD24 controls expansion and persistence of autoreactive T cells in the central nervous system during experimental autoimmune encephalomyelitis. J Exp Med. 2004;200:447-58 pubmed
Fujii S, Liu K, Smith C, Bonito A, Steinman R. The linkage of innate to adaptive immunity via maturing dendritic cells in vivo requires CD40 ligation in addition to antigen presentation and CD80/86 costimulation. J Exp Med. 2004;199:1607-18 pubmed
Arens R, Schepers K, Nolte M, van Oosterwijk M, van Lier R, Schumacher T, et al. Tumor rejection induced by CD70-mediated quantitative and qualitative effects on effector CD8+ T cell formation. J Exp Med. 2004;199:1595-605 pubmed
Jahng A, Maricic I, Aguilera C, Cardell S, Halder R, Kumar V. Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide. J Exp Med. 2004;199:947-57 pubmed
Sugimoto T, Ishikawa Y, Yoshimoto T, Hayashi N, Fujimoto J, Nakanishi K. Interleukin 18 acts on memory T helper cells type 1 to induce airway inflammation and hyperresponsiveness in a naive host mouse. J Exp Med. 2004;199:535-45 pubmed
Tyznik A, Sun J, Bevan M. The CD8 population in CD4-deficient mice is heavily contaminated with MHC class II-restricted T cells. J Exp Med. 2004;199:559-65 pubmed
Schmieg J, Yang G, Franck R, Tsuji M. Superior protection against malaria and melanoma metastases by a C-glycoside analogue of the natural killer T cell ligand alpha-Galactosylceramide. J Exp Med. 2003;198:1631-41 pubmed
Berg R, Crossley E, Murray S, Forman J. Memory CD8+ T cells provide innate immune protection against Listeria monocytogenes in the absence of cognate antigen. J Exp Med. 2003;198:1583-93 pubmed
Stetson D, Mohrs M, Reinhardt R, Baron J, Wang Z, Gapin L, et al. Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function. J Exp Med. 2003;198:1069-76 pubmed
Fujii S, Shimizu K, Smith C, Bonifaz L, Steinman R. Activation of natural killer T cells by alpha-galactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein. J Exp Med. 2003;198:267-79 pubmed
Salama A, Chitnis T, Imitola J, Ansari M, Akiba H, Tushima F, et al. Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis. J Exp Med. 2003;198:71-8 pubmed
Sugita S, Streilein J. Iris pigment epithelium expressing CD86 (B7-2) directly suppresses T cell activation in vitro via binding to cytotoxic T lymphocyte-associated antigen 4. J Exp Med. 2003;198:161-71 pubmed
Chen C, Seguin Devaux C, Burke N, Oriss T, Watkins S, Clipstone N, et al. Transforming growth factor beta blocks Tec kinase phosphorylation, Ca2+ influx, and NFATc translocation causing inhibition of T cell differentiation. J Exp Med. 2003;197:1689-99 pubmed
Jaeckel E, Klein L, Martin Orozco N, von Boehmer H. Normal incidence of diabetes in NOD mice tolerant to glutamic acid decarboxylase. J Exp Med. 2003;197:1635-44 pubmed
Wuthrich M, Filutowicz H, Warner T, Deepe G, Klein B. Vaccine immunity to pathogenic fungi overcomes the requirement for CD4 help in exogenous antigen presentation to CD8+ T cells: implications for vaccine development in immune-deficient hosts. J Exp Med. 2003;197:1405-16 pubmed
Reading P, Moore J, Smith G. Steroid hormone synthesis by vaccinia virus suppresses the inflammatory response to infection. J Exp Med. 2003;197:1269-78 pubmed
Linton P, Bautista B, Biederman E, Bradley E, Harbertson J, Kondrack R, et al. Costimulation via OX40L expressed by B cells is sufficient to determine the extent of primary CD4 cell expansion and Th2 cytokine secretion in vivo. J Exp Med. 2003;197:875-83 pubmed
Mauri C, Gray D, Mushtaq N, Londei M. Prevention of arthritis by interleukin 10-producing B cells. J Exp Med. 2003;197:489-501 pubmed
Yu Q, Erman B, Bhandoola A, Sharrow S, Singer A. In vitro evidence that cytokine receptor signals are required for differentiation of double positive thymocytes into functionally mature CD8+ T cells. J Exp Med. 2003;197:475-87 pubmed
Boonstra A, Asselin Paturel C, Gilliet M, Crain C, Trinchieri G, Liu Y, et al. Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligation. J Exp Med. 2003;197:101-9 pubmed
Culley F, Pollott J, Openshaw P. Age at first viral infection determines the pattern of T cell-mediated disease during reinfection in adulthood. J Exp Med. 2002;196:1381-6 pubmed
Nakamoto Y, Kaneko S, Fan H, Momoi T, Tsutsui H, Nakanishi K, et al. Prevention of hepatocellular carcinoma development associated with chronic hepatitis by anti-fas ligand antibody therapy. J Exp Med. 2002;196:1105-11 pubmed
Scheinecker C, McHugh R, Shevach E, Germain R. Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node. J Exp Med. 2002;196:1079-90 pubmed
Vicari A, Chiodoni C, Vaure C, Ait Yahia S, Dercamp C, Matsos F, et al. Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody. J Exp Med. 2002;196:541-9 pubmed
Kullberg M, Jankovic D, Gorelick P, Caspar P, Letterio J, Cheever A, et al. Bacteria-triggered CD4(+) T regulatory cells suppress Helicobacter hepaticus-induced colitis. J Exp Med. 2002;196:505-15 pubmed
Yoneyama H, Narumi S, Zhang Y, Murai M, Baggiolini M, Lanzavecchia A, et al. Pivotal role of dendritic cell-derived CXCL10 in the retention of T helper cell 1 lymphocytes in secondary lymph nodes. J Exp Med. 2002;195:1257-66 pubmed
Campbell D, Butcher E. Rapid acquisition of tissue-specific homing phenotypes by CD4(+) T cells activated in cutaneous or mucosal lymphoid tissues. J Exp Med. 2002;195:135-41 pubmed
Small B, Dressel S, Lawrence C, Drake D, Stoler M, Enelow R, et al. CD8(+) T cell-mediated injury in vivo progresses in the absence of effector T cells. J Exp Med. 2001;194:1835-46 pubmed
Wang X, Mosmann T. In vivo priming of CD4 T cells that produce interleukin (IL)-2 but not IL-4 or interferon (IFN)-gamma, and can subsequently differentiate into IL-4- or IFN-gamma-secreting cells. J Exp Med. 2001;194:1069-80 pubmed
Hawiger D, Inaba K, Dorsett Y, Guo M, Mahnke K, Rivera M, et al. Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J Exp Med. 2001;194:769-79 pubmed
Helmby H, Takeda K, Akira S, Grencis R. Interleukin (IL)-18 promotes the development of chronic gastrointestinal helminth infection by downregulating IL-13. J Exp Med. 2001;194:355-64 pubmed
Hogan R, Zhong W, Usherwood E, Cookenham T, Roberts A, Woodland D. Protection from respiratory virus infections can be mediated by antigen-specific CD4(+) T cells that persist in the lungs. J Exp Med. 2001;193:981-6 pubmed
Moser J, Altman J, Lukacher A. Antiviral CD8+ T cell responses in neonatal mice: susceptibility to polyoma virus-induced tumors is associated with lack of cytotoxic function by viral antigen-specific T cells. J Exp Med. 2001;193:595-606 pubmed
Fehniger T, Suzuki K, Ponnappan A, VanDeusen J, Cooper M, Florea S, et al. Fatal leukemia in interleukin 15 transgenic mice follows early expansions in natural killer and memory phenotype CD8+ T cells. J Exp Med. 2001;193:219-31 pubmed
Jember A, Zuberi R, Liu F, Croft M. Development of allergic inflammation in a murine model of asthma is dependent on the costimulatory receptor OX40. J Exp Med. 2001;193:387-92 pubmed
Dieli F, Sireci G, Russo D, Taniguchi M, Ivanyi J, Fernandez C, et al. Resistance of natural killer T cell-deficient mice to systemic Shwartzman reaction. J Exp Med. 2000;192:1645-52 pubmed
Walzl G, Tafuro S, Moss P, Openshaw P, Hussell T. Influenza virus lung infection protects from respiratory syncytial virus-induced immunopathology. J Exp Med. 2000;192:1317-26 pubmed
Panus J, McHeyzer Williams L, McHeyzer Williams M. Antigen-specific T helper cell function: differential cytokine expression in primary and memory responses. J Exp Med. 2000;192:1301-16 pubmed
Usherwood E, Roy D, Ward K, Surman S, Dutia B, Blackman M, et al. Control of gammaherpesvirus latency by latent antigen-specific CD8(+) T cells. J Exp Med. 2000;192:943-52 pubmed
Matsuda J, Naidenko O, Gapin L, Nakayama T, Taniguchi M, Wang C, et al. Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers. J Exp Med. 2000;192:741-54 pubmed
van Hall T -, Sijts A, Camps M, Offringa R, Melief C, Kloetzel P, et al. Differential influence on cytotoxic T lymphocyte epitope presentation by controlled expression of either proteasome immunosubunits or PA28. J Exp Med. 2000;192:483-94 pubmed
Egan P, Carding S. Downmodulation of the inflammatory response to bacterial infection by gammadelta T cells cytotoxic for activated macrophages. J Exp Med. 2000;191:2145-58 pubmed
d Ostiani C, Del Sero G, Bacci A, Montagnoli C, Spreca A, Mencacci A, et al. Dendritic cells discriminate between yeasts and hyphae of the fungus Candida albicans. Implications for initiation of T helper cell immunity in vitro and in vivo. J Exp Med. 2000;191:1661-74 pubmed
Townsend M, Fallon P, Matthews D, Jolin H, McKenzie A. T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses. J Exp Med. 2000;191:1069-76 pubmed
Nishikomori R, Ehrhardt R, Strober W. T helper type 2 cell differentiation occurs in the presence of interleukin 12 receptor beta2 chain expression and signaling. J Exp Med. 2000;191:847-58 pubmed
Nishimura H, Yajima T, Naiki Y, Tsunobuchi H, Umemura M, Itano K, et al. Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivo. J Exp Med. 2000;191:157-70 pubmed
product information
Cat.# :
560661
Brand :
BD Horizon
Name :
IFN
Format :
V450
Clone :
XMG1.2
Isotype :
Rat IgG 1
React :
Ms
Conc :
0.2 mg/ml
Apps :
IC/FCM
Size :
50 µg
Status :
RUO
more info or order :
company information