product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
CD117
catalog :
560558
quantity :
50 µg
price :
167.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
2B8
reactivity :
human, mouse
application :
flow cytometry, chromatin immunoprecipitation
more info or order :
citations: 42
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig s5a
Chorzalska A, Morgan J, Ahsan N, Treaba D, Olszewski A, Petersen M, et al. Bone marrow-specific loss of ABI1 induces myeloproliferative neoplasm with features resembling human myelofibrosis. Blood. 2018;: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4a
Stefani F, Eberstål S, Vergani S, Kristiansen T, Bengzon J. Low-dose irradiated mesenchymal stromal cells break tumor defensive properties in vivo. Int J Cancer. 2018;143:2200-2212 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig s4a
Yeh C, Nojima T, Kuraoka M, Kelsoe G. Germinal center entry not selection of B cells is controlled by peptide-MHCII complex density. Nat Commun. 2018;9:928 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s5
Stremmel C, Schuchert R, Wagner F, Thaler R, Weinberger T, Pick R, et al. Yolk sac macrophage progenitors traffic to the embryo during defined stages of development. Nat Commun. 2018;9:75 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1c
Mingay M, Chaturvedi A, Bilenky M, Cao Q, Jackson L, Hui T, et al. Vitamin C-induced epigenomic remodelling in IDH1 mutant acute myeloid leukaemia. Leukemia. 2018;32:11-20 pubmed publisher
  • flow cytometry; mouse; fig 1a
Anderson D, Grajales Reyes G, Satpathy A, Vasquez Hueichucura C, Murphy T, Murphy K. Revisiting the specificity of the MHC class?II transactivator CIITA in classical murine dendritic cells in vivo. Eur J Immunol. 2017;47:1317-1323 pubmed publisher
  • flow cytometry; human; loading ...
Salvatori G, Foligno S, Sirleto P, Genovese S, Russo S, Coletti V, et al. Sometimes it is better to wait: First Italian case of a newborn with transient abnormal myelopoiesis and a favorable prognosis. Oncol Lett. 2017;13:191-195 pubmed publisher
  • flow cytometry; mouse; loading ...
Nakamura Y, Ishimaru K, Shibata S, Nakao A. Regulation of plasma histamine levels by the mast cell clock and its modulation by stress. Sci Rep. 2017;7:39934 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2b
Corbineau S, Lassalle B, Givelet M, Souissi Sarahoui I, Firlej V, Romeo P, et al. Spermatogonial stem cells and progenitors are refractory to reprogramming to pluripotency by the transcription factors Oct3/4, c-Myc, Sox2 and Klf4. Oncotarget. 2017;8:10050-10063 pubmed publisher
  • flow cytometry; mouse; loading ...; fig st1
Johnston L, Hsu C, Krier Burris R, Chhiba K, Chien K, McKenzie A, et al. IL-33 Precedes IL-5 in Regulating Eosinophil Commitment and Is Required for Eosinophil Homeostasis. J Immunol. 2016;197:3445-3453 pubmed
  • flow cytometry; mouse; loading ...; fig 2b
Waterstrat A, Rector K, Geiger H, Liang Y. Quantitative trait gene Slit2 positively regulates murine hematopoietic stem cell numbers. Sci Rep. 2016;6:31412 pubmed publisher
  • flow cytometry; mouse; fig s1e
Yu Q, Song W, Wang D, Zeng Y. Identification of blood vascular endothelial stem cells by the expression of protein C receptor. Cell Res. 2016;26:1079-1098 pubmed publisher
  • flow cytometry; mouse; fig 3
Goetz B, An W, Mohapatra B, Zutshi N, Iseka F, Storck M, et al. A novel CBL-Bflox/flox mouse model allows tissue-selective fully conditional CBL/CBL-B double-knockout: CD4-Cre mediated CBL/CBL-B deletion occurs in both T-cells and hematopoietic stem cells. Oncotarget. 2016;7:51107-51123 pubmed publisher
  • flow cytometry; mouse; 1:100; fig 7
Miller M, Rosten P, Lemieux M, Lai C, Humphries R. Meis1 Is Required for Adult Mouse Erythropoiesis, Megakaryopoiesis and Hematopoietic Stem Cell Expansion. PLoS ONE. 2016;11:e0151584 pubmed publisher
  • flow cytometry; mouse; fig 2a
Lu K, Nakagawa M, Thummar K, RATHINAM C. Slicer Endonuclease Argonaute 2 Is a Negative Regulator of Hematopoietic Stem Cell Quiescence. Stem Cells. 2016;34:1343-53 pubmed publisher
  • flow cytometry; mouse
Catarinella M, Monestiroli A, Escobar G, Fiocchi A, Tran N, Aiolfi R, et al. IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment. EMBO Mol Med. 2016;8:155-70 pubmed publisher
  • flow cytometry; mouse; 1:100
Tate M, Robinson E, Green B, McDermott B, Grieve D. Exendin-4 attenuates adverse cardiac remodelling in streptozocin-induced diabetes via specific actions on infiltrating macrophages. Basic Res Cardiol. 2016;111:1 pubmed publisher
  • flow cytometry; mouse; fig s1
Aparicio Domingo P, Romera Hernandez M, Karrich J, Cornelissen F, Papazian N, Lindenbergh Kortleve D, et al. Type 3 innate lymphoid cells maintain intestinal epithelial stem cells after tissue damage. J Exp Med. 2015;212:1783-91 pubmed publisher
  • flow cytometry; mouse; fig 2
Zhang J, Li L, Baldwin A, Friedman A, Paz Priel I. Loss of IKKβ but Not NF-κB p65 Skews Differentiation towards Myeloid over Erythroid Commitment and Increases Myeloid Progenitor Self-Renewal and Functional Long-Term Hematopoietic Stem Cells. PLoS ONE. 2015;10:e0130441 pubmed publisher
  • flow cytometry; mouse; 1:50; fig 5
Roarty K, Shore A, Creighton C, Rosen J. Ror2 regulates branching, differentiation, and actin-cytoskeletal dynamics within the mammary epithelium. J Cell Biol. 2015;208:351-66 pubmed publisher
  • flow cytometry; mouse; fig 2
Velardi E, Tsai J, Holland A, Wertheimer T, Yu V, Zakrzewski J, et al. Sex steroid blockade enhances thymopoiesis by modulating Notch signaling. J Exp Med. 2014;211:2341-9 pubmed publisher
  • flow cytometry; mouse
Rai S, Tanaka H, Suzuki M, Ogoh H, Taniguchi Y, Morita Y, et al. Clathrin assembly protein CALM plays a critical role in KIT signaling by regulating its cellular transport from early to late endosomes in hematopoietic cells. PLoS ONE. 2014;9:e109441 pubmed publisher
  • flow cytometry; mouse
Meraz I, Hearnden C, Liu X, Yang M, Williams L, Savage D, et al. Multivalent presentation of MPL by porous silicon microparticles favors T helper 1 polarization enhancing the anti-tumor efficacy of doxorubicin nanoliposomes. PLoS ONE. 2014;9:e94703 pubmed publisher
  • flow cytometry; mouse
Chan I, Jain R, Tessmer M, Gorman D, Mangadu R, Sathe M, et al. Interleukin-23 is sufficient to induce rapid de novo gut tumorigenesis, independent of carcinogens, through activation of innate lymphoid cells. Mucosal Immunol. 2014;7:842-56 pubmed publisher
  • flow cytometry; mouse
Xu Y, Swartz K, Siu K, Bhattacharyya M, Minella A. Fbw7-dependent cyclin E regulation ensures terminal maturation of bone marrow erythroid cells by restraining oxidative metabolism. Oncogene. 2014;33:3161-71 pubmed publisher
  • flow cytometry; mouse; 1:100
Forand A, Beck L, Leroy C, Rousseau A, Boitez V, Cohen I, et al. EKLF-driven PIT1 expression is critical for mouse erythroid maturation in vivo and in vitro. Blood. 2013;121:666-78 pubmed publisher
  • flow cytometry; mouse
Ohmori S, Takai J, Ishijima Y, Suzuki M, Moriguchi T, Philipsen S, et al. Regulation of GATA factor expression is distinct between erythroid and mast cell lineages. Mol Cell Biol. 2012;32:4742-55 pubmed publisher
  • chromatin immunoprecipitation; mouse
Stone J, McMillan R, Skaar D, Bradshaw J, Jirtle R, Sikes M. DNA double-strand breaks relieve USF-mediated repression of D?2 germline transcription in developing thymocytes. J Immunol. 2012;188:2266-75 pubmed publisher
Matte Martone C, Liu J, Zhou M, Chikina M, Green D, Harty J, et al. Differential requirements for myeloid leukemia IFN-γ conditioning determine graft-versus-leukemia resistance and sensitivity. J Clin Invest. 2017;127:2765-2776 pubmed publisher
Liu W, Yu W, Zhang J, Chan R, Loh M, Zhang Z, et al. Inhibition of the Gab2/PI3K/mTOR signaling ameliorates myeloid malignancy caused by Ptpn11 (Shp2) gain-of-function mutations. Leukemia. 2017;31:1415-1422 pubmed publisher
Olsson A, Venkatasubramanian M, Chaudhri V, Aronow B, Salomonis N, Singh H, et al. Single-cell analysis of mixed-lineage states leading to a binary cell fate choice. Nature. 2016;537:698-702 pubmed publisher
Souilhol C, Gonneau C, Lendínez J, Batsivari A, Rybtsov S, Wilson H, et al. Inductive interactions mediated by interplay of asymmetric signalling underlie development of adult haematopoietic stem cells. Nat Commun. 2016;7:10784 pubmed publisher
Regha K, Assi S, Tsoulaki O, Gilmour J, Lacaud G, Bonifer C. Developmental-stage-dependent transcriptional response to leukaemic oncogene expression. Nat Commun. 2015;6:7203 pubmed publisher
Lujan E, Zunder E, Ng Y, Goronzy I, Nolan G, Wernig M. Early reprogramming regulators identified by prospective isolation and mass cytometry. Nature. 2015;521:352-6 pubmed publisher
Cunha M, Lima F, Vinolo M, Hastreiter A, Curi R, Borelli P, et al. Protein malnutrition induces bone marrow mesenchymal stem cells commitment to adipogenic differentiation leading to hematopoietic failure. PLoS ONE. 2013;8:e58872 pubmed publisher
Krueger A, Garbe A, von Boehmer H. Phenotypic plasticity of T cell progenitors upon exposure to Notch ligands. J Exp Med. 2006;203:1977-84 pubmed
Iwasaki H, Mizuno S, Mayfield R, Shigematsu H, Arinobu Y, Seed B, et al. Identification of eosinophil lineage-committed progenitors in the murine bone marrow. J Exp Med. 2005;201:1891-7 pubmed
Weller C, Collington S, Brown J, Miller H, Al Kashi A, Clark P, et al. Leukotriene B4, an activation product of mast cells, is a chemoattractant for their progenitors. J Exp Med. 2005;201:1961-71 pubmed
Dakic A, Metcalf D, Di Rago L, Mifsud S, Wu L, Nutt S. PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis. J Exp Med. 2005;201:1487-502 pubmed
Nutt S, Metcalf D, D Amico A, Polli M, Wu L. Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors. J Exp Med. 2005;201:221-31 pubmed
Yuasa T, Ono M, Watanabe T, Takai T. Lyn is essential for fcgamma receptor III-mediated systemic anaphylaxis but not for the Arthus reaction. J Exp Med. 2001;193:563-72 pubmed
Lohoff M, Duncan G, Ferrick D, Mittrucker H, Bischof S, Prechtl S, et al. Deficiency in the transcription factor interferon regulatory factor (IRF)-2 leads to severely compromised development of natural killer and T helper type 1 cells. J Exp Med. 2000;192:325-36 pubmed
product information
Cat.# :
560558
Brand :
BD Horizon
Name :
CD117
Format :
V450
Clone :
2B8
Isotype :
Rat IgG 2b
React :
Ms
Conc :
0.2 mg/ml
Apps :
FCM
Size :
50 µg
Status :
RUO
List Price :
167.00 USD
more info or order :
company information