product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
CD11b/Mac-1
catalog :
560480
quantity :
120 Tests
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
ICRF44
reactivity :
African green monkey, crab eating macaque, human, mouse
application :
immunohistochemistry, flow cytometry, immunohistochemistry - frozen section, blocking or activating experiments
more info or order :
citations: 43
Published Application/Species/Sample/DilutionReference
  • flow cytometry; African green monkey; loading ...; fig 1e
BURNS J, Cotleur B, Walther D, Bajrami B, Rubino S, Wei R, et al. Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain. elife. 2020;9: pubmed publisher
  • flow cytometry; human; 1:200; loading ...; fig 7d
Azcutia V, Kelm M, Luissint A, Boerner K, Flemming S, Quirós M, et al. Neutrophil expressed CD47 regulates CD11b/CD18-dependent neutrophil transepithelial migration in the intestine in vivo. Mucosal Immunol. 2020;: pubmed publisher
  • flow cytometry; human; loading ...; fig 3b, 3c
Bekeschus S, Ressel V, Freund E, Gelbrich N, Mustea A, Stope M. Gas Plasma-Treated Prostate Cancer Cells Augment Myeloid Cell Activity and Cytotoxicity. Antioxidants (Basel). 2020;9: pubmed publisher
  • flow cytometry; human; loading ...; fig 5a
Banki Z, Krabbendam L, Klaver D, Leng T, Kruis S, Mehta H, et al. Antibody opsonization enhances MAIT cell responsiveness to bacteria via a TNF-dependent mechanism. Immunol Cell Biol. 2019;97:538-551 pubmed publisher
  • flow cytometry; human; loading ...; fig 4b
Canté Barrett K, Mendes R, Li Y, Vroegindeweij E, Pike Overzet K, Wabeke T, et al. Loss of CD44dim Expression from Early Progenitor Cells Marks T-Cell Lineage Commitment in the Human Thymus. Front Immunol. 2017;8:32 pubmed publisher
  • flow cytometry; crab eating macaque; fig 3d
Wonderlich E, Swan Z, Bissel S, Hartman A, Carney J, O Malley K, et al. Widespread Virus Replication in Alveoli Drives Acute Respiratory Distress Syndrome in Aerosolized H5N1 Influenza Infection of Macaques. J Immunol. 2017;198:1616-1626 pubmed publisher
  • flow cytometry; human; loading ...; fig 4a
Faivre V, Lukaszewicz A, Payen D. Downregulation of Blood Monocyte HLA-DR in ICU Patients Is Also Present in Bone Marrow Cells. PLoS ONE. 2016;11:e0164489 pubmed publisher
  • flow cytometry; human; loading ...; fig 4e
Machacek C, Supper V, Leksa V, Mitulovic G, Spittler A, Drbal K, et al. Folate Receptor ? Regulates Integrin CD11b/CD18 Adhesion of a Macrophage Subset to Collagen. J Immunol. 2016;197:2229-38 pubmed publisher
  • flow cytometry; human; loading ...
Ashizawa T, Iizuka A, Nonomura C, Kondou R, Maeda C, Miyata H, et al. Antitumor Effect of Programmed Death-1 (PD-1) Blockade in Humanized the NOG-MHC Double Knockout Mouse. Clin Cancer Res. 2017;23:149-158 pubmed publisher
  • flow cytometry; human; loading ...; fig s8a
Theurl I, Hilgendorf I, Nairz M, Tymoszuk P, Haschka D, Asshoff M, et al. On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver. Nat Med. 2016;22:945-51 pubmed publisher
  • flow cytometry; human; 1:25; fig s2c
Reinisch A, Thomas D, Corces M, Zhang X, Gratzinger D, Hong W, et al. A humanized bone marrow ossicle xenotransplantation model enables improved engraftment of healthy and leukemic human hematopoietic cells. Nat Med. 2016;22:812-21 pubmed publisher
  • flow cytometry; African green monkey; loading ...
Phuah J, Wong E, Gideon H, Maiello P, Coleman M, Hendricks M, et al. Effects of B Cell Depletion on Early Mycobacterium tuberculosis Infection in Cynomolgus Macaques. Infect Immun. 2016;84:1301-1311 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 5
Harney A, Arwert E, Entenberg D, Wang Y, Guo P, Qian B, et al. Real-Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage-Derived VEGFA. Cancer Discov. 2015;5:932-43 pubmed publisher
  • blocking or activating experiments; human; fig 7
Hünniger K, Bieber K, Martin R, Lehnert T, Figge M, Löffler J, et al. A second stimulus required for enhanced antifungal activity of human neutrophils in blood is provided by anaphylatoxin C5a. J Immunol. 2015;194:1199-210 pubmed publisher
  • flow cytometry; human; fig 1
Boltjes A, van Montfoort N, Biesta P, Op den Brouw M, Kwekkeboom J, van der Laan L, et al. Kupffer cells interact with hepatitis B surface antigen in vivo and in vitro, leading to proinflammatory cytokine production and natural killer cell function. J Infect Dis. 2015;211:1268-78 pubmed publisher
  • flow cytometry; human; fig 4
Llosa N, Cruise M, Tam A, Wicks E, Hechenbleikner E, Taube J, et al. The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints. Cancer Discov. 2015;5:43-51 pubmed publisher
  • flow cytometry; human; loading ...; fig 5
Weed D, Vella J, Reis I, De La Fuente A, Gomez C, Sargi Z, et al. Tadalafil reduces myeloid-derived suppressor cells and regulatory T cells and promotes tumor immunity in patients with head and neck squamous cell carcinoma. Clin Cancer Res. 2015;21:39-48 pubmed publisher
  • immunohistochemistry; human
Farley A, Morris L, Vroegindeweij E, Depreter M, Vaidya H, Stenhouse F, et al. Dynamics of thymus organogenesis and colonization in early human development. Development. 2013;140:2015-26 pubmed publisher
Stik G, Vidal E, Barrero M, Cuartero S, Vila Casadesús M, Mendieta Esteban J, et al. CTCF is dispensable for immune cell transdifferentiation but facilitates an acute inflammatory response. Nat Genet. 2020;52:655-661 pubmed publisher
Tian R, Pan Y, Etheridge T, Deshmukh H, Gulick D, Gibson G, et al. Pitfalls in Single Clone CRISPR-Cas9 Mutagenesis to Fine-map Regulatory Intervals. Genes (Basel). 2020;11: pubmed publisher
Rashid A, Duan X, Gao F, Yang M, Yen A. Roscovitine enhances all-trans retinoic acid (ATRA)-induced nuclear enrichment of an ensemble of activated signaling molecules and augments ATRA-induced myeloid cell differentiation. Oncotarget. 2020;11:1017-1036 pubmed publisher
Rundgren I, Ersvær E, Ahmed A, Ryningen A, Bruserud Ø. Circulating monocyte subsets in multiple myeloma patients receiving autologous stem cell transplantation - a study of the preconditioning status and the course until posttransplant reconstitution for a consecutive group of patients. BMC Immunol. 2019;20:39 pubmed publisher
Chen Q, Wang J, Zhang Q, Zhang J, Lou Y, Yang J, et al. Tumour cell-derived debris and IgG synergistically promote metastasis of pancreatic cancer by inducing inflammation via tumour-associated macrophages. Br J Cancer. 2019;121:786-795 pubmed publisher
Kim Y, Lee S, Kim S, Jang H, Hwang I, Jin S, et al. Toll-like receptor mediated inflammation requires FASN-dependent MYD88 palmitoylation. Nat Chem Biol. 2019;15:907-916 pubmed publisher
Yoyen Ermis D, Tunali G, Tavukcuoglu E, Horzum U, Ozkazanç D, Sutlu T, et al. Myeloid maturation potentiates STAT3-mediated atypical IFN-γ signaling and upregulation of PD-1 ligands in AML and MDS. Sci Rep. 2019;9:11697 pubmed publisher
Ruiz Gutierrez M, Bölükbaşı Ö, Alexe G, Kotini A, Ballotti K, Joyce C, et al. Therapeutic discovery for marrow failure with MDS predisposition using pluripotent stem cells. JCI Insight. 2019;5: pubmed publisher
Trump L, Nayak R, Singh A, Emberesh S, Wellendorf A, LUTZKO C, et al. Neutrophils Derived from Genetically Modified Human Induced Pluripotent Stem Cells Circulate and Phagocytose Bacteria In Vivo. Stem Cells Transl Med. 2019;8:557-567 pubmed publisher
Kennedy J, Steain M, Slobedman B, Abendroth A. Infection and Functional Modulation of Human Monocytes and Macrophages by Varicella-Zoster Virus. J Virol. 2019;93: pubmed publisher
Barth N, Marwick J, Heeb M, Gale A, Rossi A, Dransfield I. Augmentation of Human Monocyte Responses to Lipopolysaccharide by the Protein S and Mer/Tyro3 Receptor Tyrosine Kinase Axis. J Immunol. 2018;201:2602-2611 pubmed publisher
Kiffin R, Grauers Wiktorin H, Nilsson M, Aurelius J, Aydin E, Lenox B, et al. Anti-Leukemic Properties of Histamine in Monocytic Leukemia: The Role of NOX2. Front Oncol. 2018;8:218 pubmed publisher
Bartlett D, Willis L, Slentz C, Hoselton A, KELLY L, Huebner J, et al. Ten weeks of high-intensity interval walk training is associated with reduced disease activity and improved innate immune function in older adults with rheumatoid arthritis: a pilot study. Arthritis Res Ther. 2018;20:127 pubmed publisher
Qian P, De Kumar B, He X, Nolte C, Gogol M, Ahn Y, et al. Retinoid-Sensitive Epigenetic Regulation of the Hoxb Cluster Maintains Normal Hematopoiesis and Inhibits Leukemogenesis. Cell Stem Cell. 2018;22:740-754.e7 pubmed publisher
Pircher J, Czermak T, Ehrlich A, Eberle C, Gaitzsch E, Margraf A, et al. Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation. Nat Commun. 2018;9:1523 pubmed publisher
Messlinger H, Sebald H, Heger L, Dudziak D, Bogdan C, Schleicher U. Monocyte-Derived Signals Activate Human Natural Killer Cells in Response to Leishmania Parasites. Front Immunol. 2018;9:24 pubmed publisher
Di Costanzo A, Del Gaudio N, Conte L, Dell aversana C, Vermeulen M, De The H, et al. The HDAC inhibitor SAHA regulates CBX2 stability via a SUMO-triggered ubiquitin-mediated pathway in leukemia. Oncogene. 2018;37:2559-2572 pubmed publisher
Macdonald R, Shrimp J, Jiang H, Zhang L, Lin H, Yen A. Probing the requirement for CD38 in retinoic acid-induced HL-60 cell differentiation with a small molecule dimerizer and genetic knockout. Sci Rep. 2017;7:17406 pubmed publisher
Raffel S, Falcone M, Kneisel N, Hansson J, Wang W, Lutz C, et al. BCAT1 restricts ?KG levels in AML stem cells leading to IDHmut-like DNA hypermethylation. Nature. 2017;551:384-388 pubmed publisher
Bracq L, Xie M, Lambelé M, Vu L, Matz J, Schmitt A, et al. T Cell-Macrophage Fusion Triggers Multinucleated Giant Cell Formation for HIV-1 Spreading. J Virol. 2017;91: pubmed publisher
Mattila J, Beaino W, Maiello P, Coleman M, White A, Scanga C, et al. Positron Emission Tomography Imaging of Macaques with Tuberculosis Identifies Temporal Changes in Granuloma Glucose Metabolism and Integrin ?4?1-Expressing Immune Cells. J Immunol. 2017;199:806-815 pubmed publisher
Bzowska M, Nogieć A, Bania K, Zygmunt M, Zarebski M, Dobrucki J, et al. Involvement of cell surface 90 kDa heat shock protein (HSP90) in pattern recognition by human monocyte-derived macrophages. J Leukoc Biol. 2017;102:763-774 pubmed publisher
Nouri Shirazi M, Bible B, Zeng M, Tamjidi S, Bossart G. Phenotyping and comparing the immune cell populations of free-ranging Atlantic bottlenose dolphins (Tursiops truncatus) and dolphins under human care. BMC Vet Res. 2017;13:78 pubmed publisher
Hafezi Moghadam A, Thomas K, Prorock A, Huo Y, Ley K. L-selectin shedding regulates leukocyte recruitment. J Exp Med. 2001;193:863-72 pubmed
Kjøller L, Hall A. Rac mediates cytoskeletal rearrangements and increased cell motility induced by urokinase-type plasminogen activator receptor binding to vitronectin. J Cell Biol. 2001;152:1145-57 pubmed
product information
Cat.# :
560480
Brand :
BD Horizon
Name :
CD11b/Mac-1
Format :
V450
Clone :
ICRF44 (also known as 44
Isotype :
Ms IgG 1
React :
Hu
Apps :
FCM
Size :
120 Tests
Status :
RUO
more info or order :
company information