product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Ly-6G and Ly-6C Gr-1
catalog :
560453
quantity :
0.1 mg
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
RB6-8C5
reactivity :
human, mouse
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 201
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig s1e
Gopal A, Ibrahim R, Fuller M, Umlandt P, Parker J, Tran J, et al. TIRAP drives myelosuppression through an Ifnγ-Hmgb1 axis that disrupts the endothelial niche in mice. J Exp Med. 2022;219: pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 3b
Yin H, Zhang X, Yang P, Zhang X, Peng Y, Li D, et al. RNA m6A methylation orchestrates cancer growth and metastasis via macrophage reprogramming. Nat Commun. 2021;12:1394 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 1a
Crespo M, González Terán B, Nikolic I, Mora A, Folgueira C, Rodriguez E, et al. Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
Aydin E, Hallner A, Grauers Wiktorin H, Staffas A, Hellstrand K, Martner A. NOX2 inhibition reduces oxidative stress and prolongs survival in murine KRAS-induced myeloproliferative disease. Oncogene. 2019;38:1534-1543 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2c
Chang S, Kim Y, Kim Y, Kim Y, Moon S, Lee Y, et al. Taurodeoxycholate Increases the Number of Myeloid-Derived Suppressor Cells That Ameliorate Sepsis in Mice. Front Immunol. 2018;9:1984 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4a
Li H, Li D, He Z, Fan J, Li Q, Liu X, et al. The effects of Nrf2 knockout on regulation of benzene-induced mouse hematotoxicity. Toxicol Appl Pharmacol. 2018;358:56-67 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s4a
Metghalchi S, Vandestienne M, Haddad Y, Esposito B, Dairou J, Tedgui A, et al. Indoleamine 2 3-dioxygenase knockout limits angiotensin II-induced aneurysm in low density lipoprotein receptor-deficient mice fed with high fat diet. PLoS ONE. 2018;13:e0193737 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s4c
Vo L, Kinney M, Liu X, Zhang Y, Barragan J, Sousa P, et al. Regulation of embryonic haematopoietic multipotency by EZH1. Nature. 2018;553:506-510 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
Laffont S, Blanquart E, Savignac M, Cenac C, Laverny G, Metzger D, et al. Androgen signaling negatively controls group 2 innate lymphoid cells. J Exp Med. 2017;214:1581-1592 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; fig 4b
Klein J, Moses K, Zelinskyy G, Sody S, Buer J, Lang S, et al. Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth. Nat Commun. 2017;8:14600 pubmed publisher
  • flow cytometry; mouse; fig 4e
Kostarnoy A, Gancheva P, Lepenies B, Tukhvatulin A, Dzharullaeva A, Polyakov N, et al. Receptor Mincle promotes skin allergies and is capable of recognizing cholesterol sulfate. Proc Natl Acad Sci U S A. 2017;114:E2758-E2765 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 6B
Mirotti L, Alberca Custódio R, Gomes E, Rammauro F, de Araujo E, Garcia Calich V, et al. CpG-ODN Shapes Alum Adjuvant Activity Signaling via MyD88 and IL-10. Front Immunol. 2017;8:47 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4b
Jiang X, Park C, Geddes Sweeney J, Yoo M, Gaide O, Kupper T. Dermal ?? T Cells Do Not Freely Re-Circulate Out of Skin and Produce IL-17 to Promote Neutrophil Infiltration during Primary Contact Hypersensitivity. PLoS ONE. 2017;12:e0169397 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3a
Wiesmeier M, Gautam S, Kirschnek S, Hacker G. Characterisation of Neutropenia-Associated Neutrophil Elastase Mutations in a Murine Differentiation Model In Vitro and In Vivo. PLoS ONE. 2016;11:e0168055 pubmed publisher
  • flow cytometry; mouse; loading ...
Cecchinato V, Bernasconi E, Speck R, Proietti M, Sauermann U, D Agostino G, et al. Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization. J Immunol. 2017;198:184-195 pubmed
  • flow cytometry; mouse; loading ...; fig 6c
Leibacher J, Dauber K, Ehser S, Brixner V, Kollar K, Vogel A, et al. Human mesenchymal stromal cells undergo apoptosis and fragmentation after intravenous application in immune-competent mice. Cytotherapy. 2017;19:61-74 pubmed publisher
  • flow cytometry; mouse; loading ...
Ramirez Carrozzi V, Sambandam A, Zhou M, Yan D, Kang J, Wu X, et al. Combined blockade of the IL-13 and IL-33 pathways leads to a greater inhibition of type 2 inflammation over inhibition of either pathway alone. J Allergy Clin Immunol. 2017;139:705-708.e6 pubmed publisher
  • flow cytometry; mouse; fig 3
Jacoby E, Nguyen S, Fountaine T, Welp K, Gryder B, Qin H, et al. CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity. Nat Commun. 2016;7:12320 pubmed publisher
  • flow cytometry; mouse; 1:50; loading ...; fig 2g
  • western blot; human; 1:1000; fig 5g
Zhang Y, Velez Delgado A, Mathew E, Li D, Mendez F, Flannagan K, et al. Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancer. Gut. 2017;66:124-136 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2
Goto Y, Aoyama M, Sekiya T, Kakita H, Waguri Nagaya Y, Miyazawa K, et al. CXCR4+ CD45- Cells are Niche Forming for Osteoclastogenesis via the SDF-1, CXCL7, and CX3CL1 Signaling Pathways in Bone Marrow. Stem Cells. 2016;34:2733-2743 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2b
Lo T, Silveira P, Fromm P, Verma N, Vu P, Kupresanin F, et al. Characterization of the Expression and Function of the C-Type Lectin Receptor CD302 in Mice and Humans Reveals a Role in Dendritic Cell Migration. J Immunol. 2016;197:885-98 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b
Patenaude J, Perreault C. Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile. J Immunol. 2016;196:4760-70 pubmed publisher
  • flow cytometry; mouse; fig 4
Fend L, Remy Ziller C, Foloppe J, Kempf J, Cochin S, Barraud L, et al. Oncolytic virotherapy with an armed vaccinia virus in an orthotopic model of renal carcinoma is associated with modification of the tumor microenvironment. Oncoimmunology. 2016;5:e1080414 pubmed
  • flow cytometry; mouse; fig s3
Sim C, Cho Y, Kim B, Baek I, Kim Y, Lee M. 2'-5' Oligoadenylate synthetase-like 1 (OASL1) deficiency in mice promotes an effective anti-tumor immune response by enhancing the production of type I interferons. Cancer Immunol Immunother. 2016;65:663-75 pubmed publisher
  • flow cytometry; mouse; 1:500; fig 2
Miller M, Rosten P, Lemieux M, Lai C, Humphries R. Meis1 Is Required for Adult Mouse Erythropoiesis, Megakaryopoiesis and Hematopoietic Stem Cell Expansion. PLoS ONE. 2016;11:e0151584 pubmed publisher
  • flow cytometry; mouse; fig s3
Gurnik S, Devraj K, Macas J, Yamaji M, Starke J, Scholz A, et al. Angiopoietin-2-induced blood-brain barrier compromise and increased stroke size are rescued by VE-PTP-dependent restoration of Tie2 signaling. Acta Neuropathol. 2016;131:753-73 pubmed publisher
  • flow cytometry; mouse; fig s3
Lancaster G, Kammoun H, Kraakman M, Kowalski G, Bruce C, Febbraio M. PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications. Nat Commun. 2016;7:10626 pubmed publisher
  • flow cytometry; mouse
Maelfait J, Roose K, Vereecke L, Mc Guire C, Sze M, Schuijs M, et al. A20 Deficiency in Lung Epithelial Cells Protects against Influenza A Virus Infection. PLoS Pathog. 2016;12:e1005410 pubmed publisher
  • flow cytometry; mouse; loading ...; tbl 1
Goldberg G, Cornish A, Murphy J, Pang E, Lim L, Campbell I, et al. G-CSF and Neutrophils Are Nonredundant Mediators of Murine Experimental Autoimmune Uveoretinitis. Am J Pathol. 2016;186:172-84 pubmed publisher
  • flow cytometry; mouse; fig 4
Scholz A, Harter P, Cremer S, Yalcin B, Gurnik S, Yamaji M, et al. Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma. EMBO Mol Med. 2016;8:39-57 pubmed publisher
  • flow cytometry; mouse
Skeldon A, Morizot A, Douglas T, Santoro N, Kursawe R, Kozlitina J, et al. Caspase-12, but Not Caspase-11, Inhibits Obesity and Insulin Resistance. J Immunol. 2016;196:437-47 pubmed publisher
  • flow cytometry; mouse; fig 2
Majumder K, Arora N, Modi S, Chugh R, Nomura A, Giri B, et al. A Novel Immunocompetent Mouse Model of Pancreatic Cancer with Robust Stroma: a Valuable Tool for Preclinical Evaluation of New Therapies. J Gastrointest Surg. 2016;20:53-65; discussion 65 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500; fig 7
  • flow cytometry; human; 1:200; fig 7
Riesenberg S, Groetchen A, Siddaway R, Bald T, Reinhardt J, Smorra D, et al. MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment. Nat Commun. 2015;6:8755 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a
Becker P, Hervouet C, Mason G, KWON S, Klavinskis L. Skin vaccination with live virus vectored microneedle arrays induce long lived CD8(+) T cell memory. Vaccine. 2015;33:4691-8 pubmed publisher
  • flow cytometry; mouse; fig 5
Lin X, Xu W, Shao M, Fan Q, Wen G, Li C, et al. Shenling Baizhu San supresses colitis associated colorectal cancer through inhibition of epithelial-mesenchymal transition and myeloid-derived suppressor infiltration. BMC Complement Altern Med. 2015;15:126 pubmed publisher
  • flow cytometry; mouse; fig 8
Gardner J, Mamotte C, Patel P, Yeoh T, Jackaman C, Nelson D. Mesothelioma tumor cells modulate dendritic cell lipid content, phenotype and function. PLoS ONE. 2015;10:e0123563 pubmed publisher
  • flow cytometry; mouse; fig 3
Fahl S, Harris B, Coffey F, Wiest D. Rpl22 Loss Impairs the Development of B Lymphocytes by Activating a p53-Dependent Checkpoint. J Immunol. 2015;194:200-9 pubmed
  • flow cytometry; mouse
Rai S, Tanaka H, Suzuki M, Ogoh H, Taniguchi Y, Morita Y, et al. Clathrin assembly protein CALM plays a critical role in KIT signaling by regulating its cellular transport from early to late endosomes in hematopoietic cells. PLoS ONE. 2014;9:e109441 pubmed publisher
  • flow cytometry; mouse
Castro Rojas C, Deason K, Hussain R, Hayardeny L, Cravens P, Yarovinsky F, et al. Testing effects of glatiramer acetate and fingolimod in an infectious model of CNS immune surveillance. J Neuroimmunol. 2014;276:232-5 pubmed publisher
  • flow cytometry; mouse
Parker K, Sinha P, Horn L, Clements V, Yang H, Li J, et al. HMGB1 enhances immune suppression by facilitating the differentiation and suppressive activity of myeloid-derived suppressor cells. Cancer Res. 2014;74:5723-33 pubmed publisher
  • flow cytometry; mouse
Chiu Y, Lin I, Su S, Wang K, Yang S, Tsai D, et al. Transcription factor ABF-1 suppresses plasma cell differentiation but facilitates memory B cell formation. J Immunol. 2014;193:2207-17 pubmed publisher
  • flow cytometry; mouse
Jakobsson T, Vedin L, Hassan T, Venteclef N, Greco D, D AMATO M, et al. The oxysterol receptor LXR? protects against DSS- and TNBS-induced colitis in mice. Mucosal Immunol. 2014;7:1416-28 pubmed publisher
  • flow cytometry; mouse
Zhang Y, Yan W, Mathew E, Bednar F, Wan S, Collins M, et al. CD4+ T lymphocyte ablation prevents pancreatic carcinogenesis in mice. Cancer Immunol Res. 2014;2:423-35 pubmed publisher
  • flow cytometry; mouse
Meraz I, Hearnden C, Liu X, Yang M, Williams L, Savage D, et al. Multivalent presentation of MPL by porous silicon microparticles favors T helper 1 polarization enhancing the anti-tumor efficacy of doxorubicin nanoliposomes. PLoS ONE. 2014;9:e94703 pubmed publisher
  • flow cytometry; mouse
Pilling D, Gomer R. Persistent lung inflammation and fibrosis in serum amyloid P component (APCs-/-) knockout mice. PLoS ONE. 2014;9:e93730 pubmed publisher
  • flow cytometry; mouse; fig s2
Bignon A, Gaudin F, Hemon P, Tharinger H, Mayol K, Walzer T, et al. CCR1 inhibition ameliorates the progression of lupus nephritis in NZB/W mice. J Immunol. 2014;192:886-96 pubmed publisher
  • flow cytometry; mouse
Chan I, Jain R, Tessmer M, Gorman D, Mangadu R, Sathe M, et al. Interleukin-23 is sufficient to induce rapid de novo gut tumorigenesis, independent of carcinogens, through activation of innate lymphoid cells. Mucosal Immunol. 2014;7:842-56 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Watanabe J, Shetty A, Hattiangady B, Kim D, Foraker J, Nishida H, et al. Administration of TSG-6 improves memory after traumatic brain injury in mice. Neurobiol Dis. 2013;59:86-99 pubmed publisher
  • flow cytometry; mouse; fig 5
Godfrey D, Kennedy J, Mombaerts P, Tonegawa S, Zlotnik A. Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8- thymocyte differentiation. J Immunol. 1994;152:4783-92 pubmed
Amobi McCloud A, Muthuswamy R, Battaglia S, Yu H, Liu T, Wang J, et al. IDO1 Expression in Ovarian Cancer Induces PD-1 in T Cells via Aryl Hydrocarbon Receptor Activation. Front Immunol. 2021;12:678999 pubmed publisher
Caronni N, Piperno G, Simoncello F, Romano O, Vodret S, Yanagihashi Y, et al. TIM4 expression by dendritic cells mediates uptake of tumor-associated antigens and anti-tumor responses. Nat Commun. 2021;12:2237 pubmed publisher
Sheng W, Liu Y, Chakraborty D, Debo B, Shi Y. Simultaneous Inhibition of LSD1 and TGFβ Enables Eradication of Poorly Immunogenic Tumors with Anti-PD-1 Treatment. Cancer Discov. 2021;11:1970-1981 pubmed publisher
Ajina R, Malchiodi Z, Fitzgerald A, Zuo A, Wang S, Moussa M, et al. Antitumor T-cell Immunity Contributes to Pancreatic Cancer Immune Resistance. Cancer Immunol Res. 2021;9:386-400 pubmed publisher
Wu Y, Chou T, Young L, Hsieh F, Pan H, Mo S, et al. Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation. Cell Death Dis. 2020;11:305 pubmed publisher
Khumalo J, Kirstein F, Scibiorek M, Hadebe S, Brombacher F. Therapeutic and prophylactic deletion of IL-4Ra-signaling ameliorates established ovalbumin induced allergic asthma. Allergy. 2020;75:1347-1360 pubmed publisher
Chen Q, Wang J, Zhang Q, Zhang J, Lou Y, Yang J, et al. Tumour cell-derived debris and IgG synergistically promote metastasis of pancreatic cancer by inducing inflammation via tumour-associated macrophages. Br J Cancer. 2019;121:786-795 pubmed publisher
Shehata L, Maurer D, Wec A, Lilov A, Champney E, Sun T, et al. Affinity Maturation Enhances Antibody Specificity but Compromises Conformational Stability. Cell Rep. 2019;28:3300-3308.e4 pubmed publisher
Kalinina A, Silaeva Y, Kazansky D, Khromykh L. The Role of Recombinant Human Cyclophilin A in the Antitumor Immune Response. Acta Naturae. 2019;11:63-67 pubmed publisher
Mora Cartín R, Gutiérrez Jiménez C, Alfaro Alarcón A, Chaves Olarte E, Chacón Díaz C, Barquero Calvo E, et al. Neutrophils Dampen Adaptive Immunity in Brucellosis. Infect Immun. 2019;87: pubmed publisher
Salem M, Wallace C, Velegraki M, Li A, Ansa Addo E, Metelli A, et al. GARP Dampens Cancer Immunity by Sustaining Function and Accumulation of Regulatory T Cells in the Colon. Cancer Res. 2019;: pubmed publisher
Lee Y, Ju J, Shon W, Oh S, Min C, Kang M, et al. Skewed Dendritic Cell Differentiation of MyD88-Deficient Donor Bone Marrow Cells, Instead of Massive Expansion as Myeloid-Derived Suppressor Cells, Aggravates GVHD. Immune Netw. 2018;18:e44 pubmed publisher
Wilson A, Wilson K, Bilandzic M, Moffitt L, Makanji M, Gorrell M, et al. Non-Invasive Fluorescent Monitoring of Ovarian Cancer in an Immunocompetent Mouse Model. Cancers (Basel). 2018;11: pubmed publisher
Szappanos D, Tschismarov R, Perlot T, Westermayer S, Fischer K, Platanitis E, et al. The RNA helicase DDX3X is an essential mediator of innate antimicrobial immunity. PLoS Pathog. 2018;14:e1007397 pubmed publisher
Nakagawa M, RATHINAM C. Constitutive Activation of the Canonical NF-κB Pathway Leads to Bone Marrow Failure and Induction of Erythroid Signature in Hematopoietic Stem Cells. Cell Rep. 2018;25:2094-2109.e4 pubmed publisher
Grohmann M, Wiede F, Dodd G, Gurzov E, Ooi G, Butt T, et al. Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC. Cell. 2018;175:1289-1306.e20 pubmed publisher
Hsu J, Dayaram T, Tovy A, De Braekeleer E, Jeong M, Wang F, et al. PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy. Cell Stem Cell. 2018;23:700-713.e6 pubmed publisher
Bennett J, Singh K, Welle S, Boule L, Lawrence B, Gasiewicz T. Conditional deletion of Ahr alters gene expression profiles in hematopoietic stem cells. PLoS ONE. 2018;13:e0206407 pubmed publisher
Abeln M, Albers I, Peters Bernard U, Flächsig Schulz K, Kats E, Kispert A, et al. Sialic acid is a critical fetal defense against maternal complement attack. J Clin Invest. 2019;129:422-436 pubmed publisher
Mulati K, Hamanishi J, Matsumura N, Chamoto K, Mise N, Abiko K, et al. VISTA expressed in tumour cells regulates T cell function. Br J Cancer. 2019;120:115-127 pubmed publisher
Ravindranathan S, Nguyen K, Kurtz S, Frazier H, Smith S, Koppolu B, et al. Tumor-derived granulocyte colony-stimulating factor diminishes efficacy of breast tumor cell vaccines. Breast Cancer Res. 2018;20:126 pubmed publisher
Irons E, Lau J. Systemic ST6Gal-1 Is a Pro-survival Factor for Murine Transitional B Cells. Front Immunol. 2018;9:2150 pubmed publisher
Singhal M, Liu X, Inverso D, Jiang K, Dai J, He H, et al. Endothelial cell fitness dictates the source of regenerating liver vasculature. J Exp Med. 2018;215:2497-2508 pubmed publisher
Thyagarajan H, Lancaster J, Lira S, Ehrlich L. CCR8 is expressed by post-positive selection CD4-lineage thymocytes but is dispensable for central tolerance induction. PLoS ONE. 2018;13:e0200765 pubmed publisher
Diao J, Gu H, Tang M, Zhao J, Cattral M. Tumor Dendritic Cells (DCs) Derived from Precursors of Conventional DCs Are Dispensable for Intratumor CTL Responses. J Immunol. 2018;201:1306-1314 pubmed publisher
Matesanz N, Nikolic I, Leiva M, Pulgarín Alfaro M, Santamans A, Bernardo E, et al. p38α blocks brown adipose tissue thermogenesis through p38δ inhibition. PLoS Biol. 2018;16:e2004455 pubmed publisher
Wei B, Zhang R, Zhai J, Zhu J, Yang F, Yue D, et al. Suppression of Th17 Cell Response in the Alleviation of Dextran Sulfate Sodium-Induced Colitis by Ganoderma lucidum Polysaccharides. J Immunol Res. 2018;2018:2906494 pubmed publisher
Melo Cardenas J, Xu Y, Wei J, Tan C, Kong S, Gao B, et al. USP22 deficiency leads to myeloid leukemia upon oncogenic Kras activation through a PU.1 dependent mechanism. Blood. 2018;: pubmed publisher
Jehle J, Schöne B, Bagheri S, Avraamidou E, Danisch M, Frank I, et al. Elevated levels of 2-arachidonoylglycerol promote atherogenesis in ApoE-/- mice. PLoS ONE. 2018;13:e0197751 pubmed publisher
Stefani F, Eberstål S, Vergani S, Kristiansen T, Bengzon J. Low-dose irradiated mesenchymal stromal cells break tumor defensive properties in vivo. Int J Cancer. 2018;143:2200-2212 pubmed publisher
Zhu J, Liu J, Liu Z, Wu L, Shi M, Zhang J, et al. Interleukin-27 Gene Therapy Prevents the Development of Autoimmune Encephalomyelitis but Fails to Attenuate Established Inflammation due to the Expansion of CD11b+Gr-1+ Myeloid Cells. Front Immunol. 2018;9:873 pubmed publisher
Baba O, Horie T, Nakao T, Hakuno D, Nakashima Y, Nishi H, et al. MicroRNA 33 Regulates the Population of Peripheral Inflammatory Ly6Chigh Monocytes through Dual Pathways. Mol Cell Biol. 2018;38: pubmed publisher
Zheng X, Fang Z, Liu X, Deng S, Zhou P, Wang X, et al. Increased vessel perfusion predicts the efficacy of immune checkpoint blockade. J Clin Invest. 2018;128:2104-2115 pubmed publisher
Treise I, Huber E, Klein Rodewald T, Heinemeyer W, Grassmann S, Basler M, et al. Defective immuno- and thymoproteasome assembly causes severe immunodeficiency. Sci Rep. 2018;8:5975 pubmed publisher
Gopinath S, Kim M, Rakib T, Wong P, Van Zandt M, Barry N, et al. Topical application of aminoglycoside antibiotics enhances host resistance to viral infections in a microbiota-independent manner. Nat Microbiol. 2018;3:611-621 pubmed publisher
Vogl T, Stratis A, Wixler V, Voller T, Thurainayagam S, Jorch S, et al. Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation. J Clin Invest. 2018;128:1852-1866 pubmed publisher
Li Q, Dai C, Xue R, Wang P, Chen L, Han Y, et al. S100A4 Protects Myeloid-Derived Suppressor Cells from Intrinsic Apoptosis via TLR4-ERK1/2 Signaling. Front Immunol. 2018;9:388 pubmed publisher
Tusi B, Wolock S, Weinreb C, Hwang Y, Hidalgo D, Zilionis R, et al. Population snapshots predict early haematopoietic and erythroid hierarchies. Nature. 2018;555:54-60 pubmed publisher
Khoramian Tusi B, Socolovsky M. High-throughput single-cell fate potential assay of murine hematopoietic progenitors in vitro. Exp Hematol. 2018;60:21-29.e3 pubmed publisher
Zhang Q, Lee W, Kang J, Kim L, Kim Y. Integrin CD11b negatively regulates Mincle-induced signaling via the Lyn-SIRPα-SHP1 complex. Exp Mol Med. 2018;50:e439 pubmed publisher
Hsieh W, Hsu T, Chang Y, Lai M. IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells. Nat Commun. 2018;9:463 pubmed publisher
Hsu C, Meeker S, Escobar S, Brabb T, Paik J, Park H, et al. Murine norovirus inhibits B cell development in the bone marrow of STAT1-deficient mice. Virology. 2018;515:123-133 pubmed publisher
Stutz M, Ojaimi S, Allison C, Preston S, Arandjelovic P, Hildebrand J, et al. Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted. Cell Death Differ. 2018;25:951-965 pubmed publisher
Hermida M, Malta R, de S Santos M, dos Santos W. Selecting the right gate to identify relevant cells for your assay: a study of thioglycollate-elicited peritoneal exudate cells in mice. BMC Res Notes. 2017;10:695 pubmed publisher
Veselits M, Tanaka A, Chen Y, Hamel K, Mandal M, Kandasamy M, et al. Ig? ubiquitination activates PI3K signals required for endosomal sorting. J Exp Med. 2017;214:3775-3790 pubmed publisher
Fernández Ruiz D, Lau L, Ghazanfari N, Jones C, Ng W, Davey G, et al. Development of a Novel CD4+ TCR Transgenic Line That Reveals a Dominant Role for CD8+ Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-Stage Malaria. J Immunol. 2017;199:4165-4179 pubmed publisher
Lee M, Tanabe O, Shi L, Jearawiriyapaisarn N, Lucas D, Engel J. The orphan nuclear receptor TR4 regulates erythroid cell proliferation and maturation. Blood. 2017;130:2537-2547 pubmed publisher
Isoda T, Moore A, He Z, Chandra V, Aida M, Denholtz M, et al. Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate. Cell. 2017;171:103-119.e18 pubmed publisher
Xiao S, Shterev I, Zhang W, Young L, Shieh J, Moore M, et al. Sublethal Total Body Irradiation Causes Long-Term Deficits in Thymus Function by Reducing Lymphoid Progenitors. J Immunol. 2017;199:2701-2712 pubmed publisher
Sierra R, Trillo Tinoco J, Mohamed E, Yu L, Achyut B, Arbab A, et al. Anti-Jagged Immunotherapy Inhibits MDSCs and Overcomes Tumor-Induced Tolerance. Cancer Res. 2017;77:5628-5638 pubmed publisher
Jung K, Heishi T, Incio J, Huang Y, Beech E, Pinter M, et al. Targeting CXCR4-dependent immunosuppressive Ly6Clow monocytes improves antiangiogenic therapy in colorectal cancer. Proc Natl Acad Sci U S A. 2017;114:10455-10460 pubmed publisher
Bucsek M, Qiao G, MacDonald C, Giridharan T, Evans L, Niedzwecki B, et al. β-Adrenergic Signaling in Mice Housed at Standard Temperatures Suppresses an Effector Phenotype in CD8+ T Cells and Undermines Checkpoint Inhibitor Therapy. Cancer Res. 2017;77:5639-5651 pubmed publisher
Bainor A, Deng F, Wang Y, Lee P, Cantor D, Logan S, et al. Chromatin-Associated Protein SIN3B Prevents Prostate Cancer Progression by Inducing Senescence. Cancer Res. 2017;77:5339-5348 pubmed publisher
Shi X, Lin Y, Gao B, Zhang P. Impairment of Hematopoietic Precursor Cell Activation during the Granulopoietic Response to Bacteremia in Mice with Chronic-Plus-Binge Alcohol Administration. Infect Immun. 2017;85: pubmed publisher
Savage A, Liang H, Locksley R. The Development of Steady-State Activation Hubs between Adult LTi ILC3s and Primed Macrophages in Small Intestine. J Immunol. 2017;199:1912-1922 pubmed publisher
Patsalos A, Pap A, Varga T, Trencsenyi G, Contreras G, Garai I, et al. In situ macrophage phenotypic transition is affected by altered cellular composition prior to acute sterile muscle injury. J Physiol. 2017;595:5815-5842 pubmed publisher
Wu X, Dayanand K, Thylur R, Norbury C, Gowda D. Small molecule-based inhibition of MEK1/2 proteins dampens inflammatory responses to malaria, reduces parasite load, and mitigates pathogenic outcomes. J Biol Chem. 2017;292:13615-13634 pubmed publisher
Percopo C, Ma M, Rosenberg H. Administration of immunobiotic Lactobacillus plantarum delays but does not prevent lethal pneumovirus infection in Rag1-/- mice. J Leukoc Biol. 2017;102:905-913 pubmed publisher
Dudakov J, Mertelsmann A, O Connor M, Jenq R, Velardi E, Young L, et al. Loss of thymic innate lymphoid cells leads to impaired thymopoiesis in experimental graft-versus-host disease. Blood. 2017;130:933-942 pubmed publisher
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product information
Cat.# :
560453
Brand :
BD Horizon
Name :
Ly-6G and Ly-6C Gr-1
Format :
V450
Clone :
RB6-8C5
Isotype :
Rat IgG 2b
React :
Ms
Conc :
0.2 mg/ml
Apps :
FCM
Size :
0.1 mg
Status :
RUO
more info or order :
company information